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Tisseel side effects: Mastoid pain and wound purulent drainage 4 days post-op skull base surgery for pulsatile tinnitus. Tisseel and teflon fibers used to separate cerebellar artery from auditory nerve.

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September 5, 2008 · Filed Under Tisseel side effects 



Episode #54
Side Effect Date:2007-08-14
Symptoms:
Mastoid pain and wound purulent drainage 4 days post-op skull base surgery for pulsatile tinnitus. Tisseel and teflon fibers used to separate cerebellar artery from auditory nerve.
Medication Name:
TISSEEL
Diagnosis or Reason for Use:
Seal and separate teflon from the AICA and auditory nerve. Surgery was endoscopic.
Outcomes Attributed to Side Effect:
Death
Life-threatening
Hospitalization – initial or prolonged
Disability or Permanent Damage
Congenital Anomaly/Birth Defect
Required Intervention to Prevent Permanent Damage
Other Serious (Important Medical Events)
Describe Event, Problem or Product Use Error:
Enterobacter aerogenes bacterial meningitis with subdural abscess. Suspect contaminated batch of Tisseel.
Medication dose: Few CC mixed in OR by nurse
Frequency of Use: Once
Other medications used at the time of event:
None
Other Relevant History, Including Preexisting Medical Conditions:
None

Patient’s Age at the time of event: 57
Patient’s gender: M
Patient’s weight at the timeof event: 210
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