Zyvox and lactic acidosis Patient Reports February 10, 2012

Zyvox Side Effects Report #4764474-9
Zyvox side effect was reported by a Physician from SWITZERLAND on Aug 29, 2005. Male patient, 47 years of age, weighting 132.3 lb, was diagnosed with wound infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: alcoholism , cardiac failure, coma, hepatic cirrhosis, ketoacidosis, lactic acidosis, shock, upper gastrointestinal haemorrhage. Zyvox dosage: unknown. During the same period patient was treated with SPIROLACTONE, VITAMINS, MIDAZOLAM, VANCOMYCIN, LEVOFLOXACIN, CORDARONE, NITRAZEPAM. Patient was hospitalized. Patient died on 08/02/2005.

Zyvox Side Effects Report #5827940-0
Zyvox side effect was reported by a Physician from CHILE on July 18, 2008. Female patient, 60 years of age, was diagnosed with urinary tract infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: arrhythmia , asthenia, bradycardia, lactic acidosis, nausea . Zyvox dosage: unknown. Patient was hospitalized. Patient recovered.

Zyvox Side Effects Report #5845982-6
Zyvox side effect was reported by a Physician from CHILE on Aug 04, 2008. Female patient, weighting 136.7 lb, was diagnosed with urinary tract infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: arrhythmia , asthenia, bradycardia, lactic acidosis, nausea . Zyvox dosage: unknown. During the same period patient was treated with DILTIAZEM, AMIODARONE, FUROSEMIDE, ACETAMINOPHEN, FLUCONAZOLE, TRAMADOL, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Zyvox Side Effects Report #4837921-1
Zyvox side effect was reported by a Physician from SWITZERLAND on Nov 10, 2005. Male patient, child 7 years of age, was diagnosed with tuberculosis  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: anaemia, anorexia, fatigue, lactic acidosis, thrombocytopenia, vomiting. Zyvox dosage: unknown. During the same period patient was treated with COMBIVIR, KALETRA, NOPIL, VITAMIN B6, ISOZID, MYAMBUTOL, AVELOX, AMPHO. Patient was hospitalized. Patient recovered.


Zyvox Side Effects Report #4974808-8
Zyvox side effect was reported by a Health Professional from BELGIUM on Mar 28, 2006. Female patient, 63 years of age, was diagnosed with staphylococcal infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: encephalopathy, haemodialysis, hepatic steatosis, lactic acidosis, lethargy, mitochondrial myopathy, muscle atrophy. Zyvox dosage: 1200 MG (600 MG, 2 IN 1 D). During the same period patient was treated with RIFAMPICIN, CIPROFLOXACIN, CLONIDINE, BISOPROLOL FUMARATE, AMLODIPINE, PANTOPRAZOLE, METOCLOPRAMIDE, LORAZEPAM. Patient was hospitalized. Patient recovered.

Zyvox Side Effects Report #4745691-0
Zyvox side effect was reported by a Physician from JAPAN on Aug 02, 2005. Male patient, 23 years of age, was diagnosed with staphylococcal bacteraemia and was treated with Zyvox. After drug was administered, patient experienced the following side effects: complications of transplanted liver, condition aggravated, hepatic cirrhosis, lactic acidosis. Zyvox dosage: 1200 MG (600 MG, 2 IN 1 D), INTRAVENOUS. Patient died on 07/13/2005.

Zyvox Side Effects Report #4693379-7
Zyvox side effect was reported by a Physician from on May 25, 2005. Female patient, 53 years of age, was diagnosed with sepsis  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: atrial fibrillation , confusional state, diarrhoea, embolic stroke, lactic acidosis, lethargy, leukaemia recurrent, mycobacterial infection, nausea . Zyvox dosage: 1200 MG (600 MG, BID),ORAL. During the same period patient was treated with ZITHROMAX, VANCOMYCIN, MEROPENEM. Patient was hospitalized. Patient recovered.

Zyvox Side Effects Report #4960869-9
Zyvox side effect was reported by a Physician from FRANCE on Mar 15, 2006. Female patient, 25 years of age, weighting 132.3 lb, was diagnosed with sepsis , systemic lupus erythematosus and was treated with Zyvox. After drug was administered, patient experienced the following side effects: abdominal pain , catheter related infection, glomerulonephritis, hypercalcaemia, lactic acidosis, metabolic acidosis, pyrexia, renal failure, staphylococcal sepsis. Zyvox dosage: 1200 MG (2 IN 1 D), ORAL. During the same period patient was treated with CYCLOPHOSPHAMIDE, ENDOXAN, CIPROFLOXACINE, OLIVE HUILE, ALBUMINE HUMAINE, GLUCOSE. Patient was hospitalized. Patient recovered.

Zyvox Side Effects Report #4989774-9
Zyvox side effect was reported by a Physician from SWITZERLAND on Apr 19, 2006. Female patient, 67 years of age, was diagnosed with retroperitoneal infection, ill-defined disorder and was treated with Zyvox. After drug was administered, patient experienced the following side effects: coagulation factor decreased, diarrhoea, dyspnoea, haematoma infection, haemodialysis, international normalised ratio abnormal, lactic acidosis, metabolic acidosis. Zyvox dosage: 300 MG (300 MG), ORAL. During the same period patient was treated with MARCUMAR, DIFLUCAN, CIPROFLOXACIN, METRONIDAZOLE, TENORMIN, TOREM, NEXIUM. Patient was hospitalized. Patient recovered.


Zyvox Side Effects Report #5321675-9
Zyvox side effect was reported by a Health Professional from FRANCE on May 01, 2007. Male patient, 48 years of age, was diagnosed with pulmonary tuberculosis and was treated with Zyvox. After drug was administered, patient experienced the following side effects: abdominal pain , abdominal pain upper, anaemia, deafness neurosensory, dyspepsia, hepatic failure, hypothyroidism, lactic acidosis, neuropathy. Zyvox dosage: unknown. During the same period patient was treated with PARA AMINOSALICYLIC ACID, IZILOX, ETHIONAMIDE, CAPREOMYCIN, CYCLOSERINE, ETHAMBUTOL HYDROCHLORIDE, RIMIFON. Patient was hospitalized. Patient recovered.

Zyvox Side Effects Report #5118987-0
Zyvox side effect was reported by a Physician from BRAZIL on Sept 14, 2006. Male patient, 70 years of age, was diagnosed with pneumonia staphylococcal and was treated with Zyvox. After drug was administered, patient experienced the following side effects: cardiac failure, disease progression, haemorrhage, lactic acidosis, septic shock. Zyvox dosage: unknown. During the same period patient was treated with MEROPENEM, NORADRENALINE, FLUCONAZOLE. Patient died on 08/01/2006.

Zyvox Side Effects Report #5526482-X
Zyvox side effect was reported by a Pharmacist from UNITED STATES on Nov 21, 2007. Male patient, 73 years of age, weighting 216.1 lb, was diagnosed with osteomyelitis and was treated with Zyvox. After drug was administered, patient experienced the following side effects: electrolyte imbalance, haemodialysis, lactic acidosis, renal failure acute, thrombocytopenia. Zyvox dosage: 600 MG TWICE DAILY PO. Patient was hospitalized and became disabled. Patient recovered.

Zyvox Side Effects Report #5531029-8
Zyvox side effect was reported by a Pharmacist from UNITED STATES on Nov 20, 2007. Male patient, 73 years of age, weighting 102.2 lb, was diagnosed with osteomyelitis, diabetes mellitus and was treated with Zyvox. After drug was administered, patient experienced the following side effects: lactic acidosis, renal failure acute. Zyvox dosage: unknown. During the same period patient was treated with INSULIN. Patient recovered.

Zyvox Side Effects Report #5633441-5
Zyvox side effect was reported by a Pharmacist from UNITED STATES on Feb 09, 2008. Male patient, weighting 102.2 lb, was diagnosed with osteomyelitis, diabetes mellitus and was treated with Zyvox. After drug was administered, patient experienced the following side effects: acidosis, atrial fibrillation , lactic acidosis, renal failure acute. Zyvox dosage: unknown. During the same period patient was treated with INSULIN. Patient was hospitalized. Patient died on 11/21/2007.


Zyvox Side Effects Report #5525839-0
Zyvox side effect was reported by a Physician from FRANCE on Nov 14, 2007. Female patient, weighting 220.5 lb, was diagnosed with infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: cholestasis, lactic acidosis, septic shock. Zyvox dosage: unknown. During the same period patient was treated with FORTUM, TAZOCILLINE, PARACETAMOL, TRIFLUCAN, FONZYLANE, NEURONTIN, HEPARIN CALCIUM, NOREPINEPHRINE. Patient died on 10/19/2007.

Zyvox Side Effects Report #5839283-X
Zyvox side effect was reported by a Consumer or non-health professional from UNITED STATES on July 29, 2008. Male patient, weighting 155.0 lb, was diagnosed with infection  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: asthenia, dry mouth, dysgeusia, fatigue, gait disturbance, lactic acidosis. Zyvox dosage: unknown. During the same period patient was treated with COREG, LINEZOLID, LASIX, DILTIAZEM, WARFARIN. Patient recovered.

Zyvox Side Effects Report #5209909-2
Zyvox side effect was reported by a Physician from UNITED STATES on Oct 08, 2005. Female patient, 13 years of age, was diagnosed with ill-defined disorder and was treated with Zyvox. After drug was administered, patient experienced the following side effects: lactic acidosis. Zyvox dosage: unknown. Patient recovered.

Zyvox Side Effects Report #5090164-1
Zyvox side effect was reported by a Physician from UNITED STATES on Aug 10, 2006. Female patient, 74 years of age, weighting 114.6 lb, was diagnosed with enterococcal infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: abdominal pain upper, acidosis, arrhythmia , haematocrit decreased, haemoglobin decreased, lactic acidosis, malaise, platelet count decreased, white blood cell count decreased. Zyvox dosage: 1500 MG (500 MG, 3 IN 1 D), ORAL. During the same period patient was treated with ASPIRIN, BETA BLOCKER AGENTS. Patient died on 08/09/2006.

Zyvox Side Effects Report #4982627-1
Zyvox side effect was reported by a Physician from UNITED STATES on Apr 07, 2006. Female patient, 35 years of age, weighting 101.4 lb, was diagnosed with enterococcal infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: clostridial infection, lactic acidosis. Zyvox dosage: 1200 MG (600 MG, 2 IN 1 D), INTRAVENOUS. During the same period patient was treated with TENOFOVIR, EMTRICITABINE, SUSTIVA, VALTREX, ETHAMBUTOL, ATOVAQUONE, MOXIFLOXACIN. Patient recovered.


Zyvox Side Effects Report #4659369-5
Zyvox side effect was reported by a Physician from on Apr 27, 2005. Female patient, 54 years of age, was diagnosed with endocarditis bacterial, leukopenia, anaemia and was treated with Zyvox. After drug was administered, patient experienced the following side effects: agitation, hyperventilation, lactic acidosis, psychomotor agitation, vomiting. Zyvox dosage: unknown. During the same period patient was treated with FILGRASTIM, ERYTHROPOIETIN, LENOGRASTIM, ASPIRIN, BLOPRESS PLUS, LANSOPRAZOLE, SPIRONOLACTONE. Patient died on 04/24/2005.

Zyvox Side Effects Report #5209818-9
Zyvox side effect was reported by a Physician from UNITED STATES on Nov 11, 2005. Male patient, 55 years of age, was diagnosed with endocarditis  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: lactic acidosis. Zyvox dosage: 1200 MG (600 MG, BID), PARENTERAL. During the same period patient was treated with SELECTIVE BETA. Patient recovered.

Zyvox Side Effects Report #4861678-1
Zyvox side effect was reported by a Physician from UNITED STATES on Mar 02, 2005. Male patient, 55 years of age, was diagnosed with endocarditis  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: lactic acidosis. Zyvox dosage: 1200 MG (600 MG,BID),PARENTERAL. During the same period patient was treated with SELECTIVE BETA. Patient recovered.

Zyvox Side Effects Report #4705896-1
Zyvox side effect was reported by a Physician from on June 21, 2005. Male patient, 45 years of age, was diagnosed with endocarditis , ill-defined disorder and was treated with Zyvox. After drug was administered, patient experienced the following side effects: carnitine deficiency, haemorrhage, hepatic failure, hepatitis fulminant, lactic acidosis, lung disorder, metabolic acidosis, prothrombin time prolonged, shock. Zyvox dosage: 1200 MG (600 MG, BID INTERVAL: EVERY DAY) INTRAVENOUS. During the same period patient was treated with AZACTAM, PANTOPRAZOLE, VANCOMYCIN, CANCIDAS. Patient was hospitalized. Patient died on 06/03/2005.

Zyvox Side Effects Report #4769787-2
Zyvox side effect was reported by a Physician from FRANCE on Sept 01, 2005. Male patient, 45 years of age, was diagnosed with endocarditis , ill-defined disorder and was treated with Zyvox. After drug was administered, patient experienced the following side effects: carnitine deficiency, haemorrhage, hepatic failure, hepatitis fulminant, lactic acidosis, lung disorder, metabolic acidosis, shock. Zyvox dosage: 1200 MG (600 MG, BID), INTRAVENOUS. During the same period patient was treated with AZACTAM, PANTOPRAZOLE, VANCOMYCIN, CANCIDAS. Patient was hospitalized. Patient died on 06/03/2005.


Zyvox Side Effects Report #5585968-2
Zyvox side effect was reported by a Physician from UNITED STATES on May 25, 2007. Female patient, 31 years of age, was diagnosed with endocarditis  and was treated with Zyvox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, carbon dioxide abnormal, lactic acidosis. Zyvox dosage: 1200 MG (600 MG,1 IN 12 HR),INTRAVENOUS. During the same period patient was treated with CUBICIN, COREG, SEROQUEL. Patient was hospitalized and became disabled. Patient recovered.

Zyvox Side Effects Report #5577337-6
Zyvox side effect was reported by a Physician from UNITED STATES on Dec 19, 2007. Female patient, 57 years of age, weighting 211.6 lb, was diagnosed with cellulitis , enterococcal infection and was treated with Zyvox. After drug was administered, patient experienced the following side effects: acidosis, blood albumin increased, blood bicarbonate decreased, blood lactic acid increased, blood ph decreased, dyspnoea, hypoventilation, lactic acidosis, respiratory failure. Zyvox dosage: unknown. Patient was hospitalized. Patient died on 10/28/2007.

Zyvox Side Effects Report #5133063-9
Zyvox side effect was reported by a Physician from JAPAN on Oct 04, 2006. Male patient, 23 years of age, weighting 187.4 lb, was diagnosed with bacteraemia and was treated with Zyvox. After drug was administered, patient experienced the following side effects: hepatic cirrhosis, lactic acidosis. Zyvox dosage: 1200 MG (600 MG, 2 IN 1D), INTRAVENOUS. During the same period patient was treated with URSO, PROGRAF, EMTRICITABINE, VIREAD. Patient died on 07/13/2005.