Zonisamide and hepatic function abnormal Patient Reports February 12, 2012

Zonisamide Side Effects Report #5300377-9
Zonisamide side effect was reported by a Physician from JAPAN on Apr 03, 2007. Female patient, 55 years of age, was diagnosed with temporal lobe epilepsy and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: hepatic function abnormal, human herpesvirus 6 infection, lymphocyte morphology abnormal, white blood cell count increased. Zonisamide dosage: 200 MG, 1 IN 1 D, ORAL. During the same period patient was treated with NARON, BENZA BLOCK. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5268623-8
Zonisamide side effect was reported by a Physician from JAPAN on Feb 28, 2007. Female patient was diagnosed with hippocampal sclerosis and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: hepatic function abnormal, lymphocyte morphology abnormal. Zonisamide dosage: unknown. During the same period patient was treated with NARON. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5034566-8
Zonisamide side effect was reported by a Physician from JAPAN on June 14, 2006. Male patient, 85 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: anorexia, hepatic function abnormal, liver disorder, oedema peripheral, pneumonia , pulmonary oedema. Zonisamide dosage: 200 MG, ORAL. During the same period patient was treated with ASPIRIN, HALCION, OPALMON, AMAZOLON, FERROMIA, CLARITHROMYCIN, MUCODYNE, LEFTOSE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5636660-7
Zonisamide side effect was reported by a Physician from JAPAN on Feb 13, 2008. Male patient, 60 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: blister, conjunctivitis, hepatic function abnormal, pyrexia. Zonisamide dosage: 200 MG, 1 IN 1 D, ORAL. During the same period patient was treated with SPIRIVA, FLUTIDE DISKUS, VERAPAMIL HYDROCHLORIDE, DIGOXIN, ASPIRIN, FAMOTIDINE. Patient was hospitalized. Patient recovered.


Zonisamide Side Effects Report #5484876-5
Zonisamide side effect was reported by a Physician from JAPAN on Oct 02, 2007. Female patient, child 6 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: cough, cytomegalovirus infection , hepatic function abnormal, human herpesvirus 6 infection, lymphocyte stimulation test positive, respiratory disorder, viral myocarditis. Zonisamide dosage: unknown. Patient was hospitalized. Patient died on 09/10/2007.

Zonisamide Side Effects Report #5500192-7
Zonisamide side effect was reported by a Physician from JAPAN on Oct 17, 2007. Female patient, child 6 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: cardiac hypertrophy, cytomegalovirus infection , erythema infectiosum, hepatic function abnormal, human herpesvirus 6 infection, lymphocyte stimulation test positive, measles antibody positive. Zonisamide dosage: unknown. Patient was hospitalized. Patient died on 09/10/2007.

Zonisamide Side Effects Report #5015054-1
Zonisamide side effect was reported by a Physician from JAPAN on May 22, 2006. Female patient, 38 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal, hypersensitivity, rash , viral infection . Zonisamide dosage: 100 MG, ORAL. During the same period patient was treated with FAMOTIDINE, MUCOSTA, BUFFERIN, CEFDINIR, ALLELOCK. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5106358-2
Zonisamide side effect was reported by a Physician from JAPAN on Aug 29, 2006. Female patient, 30 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, disease recurrence, gamma-glutamyltransferase increased, hepatic function abnormal, human herpes virus 6 serology positive, lymphadenopathy. Zonisamide dosage: 400 MG, 2 IN 1 D, ORAL. During the same period patient was treated with LOXONIN, MUCOSTA, FAMOTIDINE, ZOLPIDEM TARTRATE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4961259-5
Zonisamide side effect was reported by a Physician from JAPAN on Mar 20, 2006. Male patient, 28 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alopecia universalis, diabetes mellitus insulin-dependent, hepatic function abnormal, loss of consciousness, tonic convulsion. Zonisamide dosage: 200 MG, 1 IN 1 D, ORAL. During the same period patient was treated with DEPAKENE. Patient was hospitalized. Patient recovered.


Zonisamide Side Effects Report #4929498-7
Zonisamide side effect was reported by a Health Professional from JAPAN on Feb 15, 2006. Male patient, 17 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal, stevens-johnson syndrome. Zonisamide dosage: 300 MG, 1 IN 1 D, ORAL. During the same period patient was treated with CALONAL, POLARAMINE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4934270-8
Zonisamide side effect was reported by a Health Professional from JAPAN on Feb 15, 2006. Male patient, 17 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, infection , stevens-johnson syndrome. Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with CALONAL, POLARAMINE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4954427-X
Zonisamide side effect was reported by a Health Professional from JAPAN on Mar 10, 2006. Male patient, 17 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal, nasopharyngitis, stevens-johnson syndrome. Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with CALONAL, POLARAMINE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5117943-6
Zonisamide side effect was reported by a Physician from JAPAN on Sept 14, 2006. Female patient, 15 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: anorexia, aplasia pure red cell, hepatic function abnormal, pallor, weight decreased. Zonisamide dosage: unknown. During the same period patient was treated with CARBAMAZEPINE, VALPROATE, CLOBAZAM. Patient recovered.

Zonisamide Side Effects Report #5121944-1
Zonisamide side effect was reported by a Physician from JAPAN on Sept 26, 2006. Female patient, 15 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: aplasia pure red cell, decreased appetite, hepatic function abnormal, pallor, weight decreased. Zonisamide dosage: unknown. During the same period patient was treated with CARBAMAZEPINE, VALPROATE, MYSTAN, LEVOTHYROXINE, CAFFEINE AND BENZOATE. Patient recovered.


Zonisamide Side Effects Report #4957769-7
Zonisamide side effect was reported by a Physician from JAPAN on Mar 16, 2006. Female patient, 43 years of age, was diagnosed with depressed level of consciousness, head injury and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal, thrombocytopenia. Zonisamide dosage: 200 MG, 1 IN 1 D; ORAL. During the same period patient was treated with PASIL, CEREB. Patient recovered.

Zonisamide Side Effects Report #4690976-X
Zonisamide side effect was reported by a Consumer or non-health professional from on June 03, 2005. Male patient, 56 years of age, was diagnosed with convulsion prophylaxis, hypertension and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: erythema, hepatic function abnormal, malaise, nausea , pigmentation disorder, pyrexia, rash . Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with CALBLOCK, EPADEL S, PERSANTIN. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4717271-4
Zonisamide side effect was reported by a Health Professional from JAPAN on June 03, 2005. Male patient, 56 years of age, was diagnosed with convulsion prophylaxis, hypertension and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: erythema, hepatic function abnormal, malaise, nausea , pyrexia. Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with CALBLOCK, EPADEL S, PERSANTIN. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5087153-X
Zonisamide side effect was reported by a Physician from JAPAN on Aug 04, 2006. Female patient, 46 years of age, was diagnosed with convulsion prophylaxis, pain  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: conjunctivitis, hepatic function abnormal, hypersensitivity, keratitis, mucosal inflammation. Zonisamide dosage: 400 MG, 2 IN 1 D, ORAL. During the same period patient was treated with LOXONIN, LACTEC, EVAMYL. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5352374-5
Zonisamide side effect was reported by a Physician from JAPAN on May 29, 2007. Female patient, 41 years of age, was diagnosed with convulsion prophylaxis and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alopecia, autoimmune disorder, fatigue, hepatic function abnormal, human herpes virus 6 serology positive, lymphocyte stimulation test positive, musculoskeletal stiffness, pancytopenia. Zonisamide dosage: 200 MG, 1 IN 1 D, ORAL. During the same period patient was treated with BETAMETHASONE, ACYCLOVIR. Patient was hospitalized. Patient recovered.


Zonisamide Side Effects Report #5087152-8
Zonisamide side effect was reported by a Physician from JAPAN on Aug 07, 2006. Female patient, 33 years of age, was diagnosed with convulsion prophylaxis and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: erythema, hepatic function abnormal, hypersensitivity, lymphadenopathy, pyrexia. Zonisamide dosage: unknown. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5106360-0
Zonisamide side effect was reported by a Physician from JAPAN on Aug 29, 2006. Female patient, 33 years of age, was diagnosed with convulsion prophylaxis and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: hepatic function abnormal, human herpes virus 6 serology positive, lymphadenopathy, pyrexia. Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with PHENOBARBITAL, PHENYTOIN, DEPAKENE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5120065-1
Zonisamide side effect was reported by a Physician from JAPAN on Sept 14, 2006. Female patient, 33 years of age, was diagnosed with convulsion prophylaxis and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alopecia, erythema, face oedema, flushing, hepatic function abnormal, human herpes virus 6 serology positive, lymphadenopathy. Zonisamide dosage: unknown. During the same period patient was treated with PHENOBARBITAL, PHENYTOIN, DEPAKENE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5755252-2
Zonisamide side effect was reported by a Physician from JAPAN on May 16, 2008. Male patient, 70 years of age, was diagnosed with convulsion and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: diarrhoea, hepatic function abnormal, hiccups, renal disorder. Zonisamide dosage: unknown. During the same period patient was treated with AMLODIPINE BESYLATE, CANDESARTAN CILEXETIL, GASMOTIN, AMOBAN, HASEN, LIPITOR, AMARYL. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5765602-9
Zonisamide side effect was reported by a Physician from JAPAN on May 21, 2008. Male patient, 70 years of age, was diagnosed with convulsion and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: anorexia, dehydration, dermatitis exfoliative, diarrhoea, eosinophilia, feeding disorder, hepatic function abnormal, hyperglycaemia, renal impairment. Zonisamide dosage: 200 MG, ORAL. During the same period patient was treated with AMLODIPINE BESYLATE, CANDESARTAN CILEXETIL, GASMOTIN, AMOBAN, BASEN, LIPITOR, AMARYL, METFORMIN HYDROCHLORIDE. Patient was hospitalized. Patient recovered.


Zonisamide Side Effects Report #4975378-0
Zonisamide side effect was reported by a Physician from JAPAN on Mar 30, 2006. Female patient, 65 years of age, was diagnosed with convulsion and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal. Zonisamide dosage: unknown. During the same period patient was treated with DEPAS, LOSARTAN POTASSIUM. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4968605-7
Zonisamide side effect was reported by a Physician from JAPAN on Mar 28, 2006. Female patient, 42 years of age, was diagnosed with convulsion, depressed level of consciousness and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal, thrombocytopenia, viral infection . Zonisamide dosage: 200 MG, 1 IN 1 D, ORAL. During the same period patient was treated with PASIL, CEREB. Patient recovered.

Zonisamide Side Effects Report #5531300-X
Zonisamide side effect was reported by a Physician from JAPAN on Nov 15, 2007. Female patient, 30 years of age, was diagnosed with convulsion and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: headache , hepatic function abnormal, liver disorder, stevens-johnson syndrome. Zonisamide dosage: 800 MG, ORAL. During the same period patient was treated with FAMOTIDINE, CEREB, LOXONIN, MUCOSTA, ZOLPIDEM TARTRATE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5694210-3
Zonisamide side effect was reported by a Physician from JAPAN on Mar 19, 2008. Male patient, child 11 years of age, was diagnosed with convulsion and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, dermatitis exfoliative, encephalitis , encephalopathy, hepatic function abnormal, human herpesvirus 6 infection, loss of consciousness, pyrexia. Zonisamide dosage: unknown. During the same period patient was treated with VALPROATE, PHENOBARBITAL, CLONAZEPAM, MIDAZOLAM, PHENYTOIN, ACYCLOVIR, RISPERDAL. Patient recovered.

Zonisamide Side Effects Report #5468379-X
Zonisamide side effect was reported by a Physician from JAPAN on Sept 12, 2007. Male patient, 59 years of age, was treated with Zonisamide. After drug was administered, patient experienced the following side effects: hepatic function abnormal, pyrexia. Zonisamide dosage: unknown. Patient recovered.


Zonisamide Side Effects Report #5203869-6
Zonisamide side effect was reported by a Health Professional from UNITED STATES on Dec 19, 2006. Female patient, 35 years of age, was treated with Zonisamide. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood chloride decreased, blood potassium decreased, coma, hepatic encephalopathy, hepatic function abnormal, intentional overdose. Zonisamide dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, CARBAMAZEPINE, TIZANIDINE, FENTANYL. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5080829-X
Zonisamide side effect was reported by a Physician from JAPAN on Aug 01, 2006. Female patient, 30 years of age, was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, eosinophil percentage increased, gamma-glutamyltransferase increased, hepatic function abnormal, lymphadenopathy. Zonisamide dosage: unknown. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4950265-2
Zonisamide side effect was reported by a Physician from JAPAN on Mar 07, 2006. Male patient, 28 years of age, was treated with Zonisamide. After drug was administered, patient experienced the following side effects: diabetes mellitus insulin-dependent, hepatic function abnormal, pyrexia. Zonisamide dosage: unknown. Patient recovered.

Zonisamide Side Effects Report #5581066-2
Zonisamide side effect was reported by a Physician from JAPAN on Dec 12, 2007. Male patient, child 1 years of age, was treated with Zonisamide. After drug was administered, patient experienced the following side effects: aplasia pure red cell, gene mutation, glucose tolerance impaired, haemolytic anaemia, hepatic function abnormal, infantile spasms, muscle spasms, musculoskeletal disorder, neutropenia. Zonisamide dosage: unknown. During the same period patient was treated with CLOBAZAM, POTASSIUM BROMIDE, VITAMIN B PREPARATIONS. Patient recovered.