Zonisamide and aspartate aminotransferase increased Patient Reports February 12, 2012

Zonisamide Side Effects Report #5216237-8
Zonisamide side effect was reported by a Consumer or non-health professional from on Jan 17, 2007. Male patient, 35 years of age, was diagnosed with weight decreased and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, cholestasis, chromaturia, fatigue, jaundice . Zonisamide dosage: unknown. During the same period patient was treated with PHENTERMINE HYDROCHLORIDE, TOPIRAMATE. Patient recovered.

Zonisamide Side Effects Report #5802610-3
Zonisamide side effect was reported by a Physician from JAPAN on June 19, 2008. Female patient, 68 years of age, was diagnosed with trigeminal neuralgia , pharyngitis and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, graft versus host disease, no therapeutic response, pemphigoid, scleroderma . Zonisamide dosage: unknown. During the same period patient was treated with CARBAMAZEPINE, MINOCYCLINE HYDROCHLORIDE. Patient recovered.

Zonisamide Side Effects Report #5097545-0
Zonisamide side effect was reported by a Physician from JAPAN on Aug 21, 2006. Male patient, 58 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood pressure decreased, diarrhoea, disseminated intravascular coagulation, eosinophilia, flatulence, haemodialysis. Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with ADALAT, VALPROATE, PHENOBARBITAL, ALLELOCK, HOMOCLOMIN, LASIX, PREDNISOLONE. Patient was hospitalized. Patient died on 07/08/2006.

Zonisamide Side Effects Report #5161376-3
Zonisamide side effect was reported by a Physician from JAPAN on Nov 06, 2006. Male patient, 58 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, anuria, aspartate aminotransferase increased, blood bilirubin increased, blood disorder, convulsion, dermatitis exfoliative, diarrhoea. Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with ADALAT, VALPROATE, PHENOBARBITAL, ALLELOCK, HOMOCLOMIN, LASIX, PREDNISOLONE. Patient died on 07/08/2006.


Zonisamide Side Effects Report #4968604-5
Zonisamide side effect was reported by a Physician from JAPAN on Mar 28, 2006. Male patient, 47 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, conjunctival adhesion, conjunctival erosion, lacrimation decreased, liver disorder, toxic epidermal necrolysis, urine output decreased. Zonisamide dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Zonisamide Side Effects Report #5518819-2
Zonisamide side effect was reported by a Physician from JAPAN on Nov 05, 2007. Male patient, 40 years of age, was diagnosed with epilepsy , peripheral nerve injury and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood alkaline phosphatase increased, liver disorder, pyrexia, rash . Zonisamide dosage: 300 MG, ORAL. During the same period patient was treated with CARBAMAZEPINE, PYRAZOLONE, PHENYTOIN, CLONAZEPAM. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5015054-1
Zonisamide side effect was reported by a Physician from JAPAN on May 22, 2006. Female patient, 38 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal, hypersensitivity, rash , viral infection . Zonisamide dosage: 100 MG, ORAL. During the same period patient was treated with FAMOTIDINE, MUCOSTA, BUFFERIN, CEFDINIR, ALLELOCK. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5034529-2
Zonisamide side effect was reported by a Physician from JAPAN on June 09, 2006. Female patient, 38 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, cytomegalovirus infection , epstein-barr virus infection, gamma-glutamyltransferase increased, oedema, respiratory disorder. Zonisamide dosage: 200 MG, ORAL. During the same period patient was treated with FAMOTIDINE, MUCOSTA, VOLTAREN, PHENYTOIN. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5106358-2
Zonisamide side effect was reported by a Physician from JAPAN on Aug 29, 2006. Female patient, 30 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, disease recurrence, gamma-glutamyltransferase increased, hepatic function abnormal, human herpes virus 6 serology positive, lymphadenopathy. Zonisamide dosage: 400 MG, 2 IN 1 D, ORAL. During the same period patient was treated with LOXONIN, MUCOSTA, FAMOTIDINE, ZOLPIDEM TARTRATE. Patient was hospitalized. Patient recovered.


Zonisamide Side Effects Report #5564594-5
Zonisamide side effect was reported by a Physician from JAPAN on Dec 05, 2007. Female patient, 30 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: abdominal pain upper, alanine aminotransferase increased, aspartate aminotransferase increased, blood immunoglobulin g increased, gamma-glutamyltransferase increased, human herpes virus 6 serology positive, immunoglobulins decreased, lymphocyte stimulation test positive. Zonisamide dosage: 200 MG OR 400 MG OR 800 MG, ORAL. During the same period patient was treated with LOXONIN, MUCOSTA, GASPER D, ZOLPIDEM TARTRATE, CERES. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4991804-5
Zonisamide side effect was reported by a Physician from JAPAN on Apr 25, 2006. Female patient, 25 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, dermatitis exfoliative, disease recurrence, herpes virus infection, lymphadenopathy. Zonisamide dosage: unknown. During the same period patient was treated with DEPAKENE, PHENYTOIN. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5613453-8
Zonisamide side effect was reported by a Health Professional from JAPAN on Jan 10, 2008. Male patient, 24 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: aggression, agitation, alanine aminotransferase increased, aspartate aminotransferase increased, incontinence, neuroleptic malignant syndrome, somnolence. Zonisamide dosage: 300 MG,. During the same period patient was treated with CARBAMAZEPINE, CLONAZEPAM. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5292453-4
Zonisamide side effect was reported by a Physician from JAPAN on Mar 26, 2007. Male patient, 20 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, dermatitis exfoliative, lymphocyte percentage increased, pigmentation disorder, purpura. Zonisamide dosage: 400 MG, ORAL. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4929498-7
Zonisamide side effect was reported by a Health Professional from JAPAN on Feb 15, 2006. Male patient, 17 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal, stevens-johnson syndrome. Zonisamide dosage: 300 MG, 1 IN 1 D, ORAL. During the same period patient was treated with CALONAL, POLARAMINE. Patient was hospitalized. Patient recovered.


Zonisamide Side Effects Report #4934270-8
Zonisamide side effect was reported by a Health Professional from JAPAN on Feb 15, 2006. Male patient, 17 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, infection , stevens-johnson syndrome. Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with CALONAL, POLARAMINE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4954427-X
Zonisamide side effect was reported by a Health Professional from JAPAN on Mar 10, 2006. Male patient, 17 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal, nasopharyngitis, stevens-johnson syndrome. Zonisamide dosage: 200 MG, 2 IN 1 D, ORAL. During the same period patient was treated with CALONAL, POLARAMINE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5636666-8
Zonisamide side effect was reported by a Physician from JAPAN on Feb 08, 2008. Male patient, 15 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, exfoliative rash, human herpesvirus 6 infection, nasopharyngitis. Zonisamide dosage: 300 MG, ORAL. During the same period patient was treated with CLARITHROMYCIN, CALONAL, FLAVERIC, HOKUNALIN TAPE. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5572348-9
Zonisamide side effect was reported by a Physician from JAPAN on Dec 11, 2007. Female patient, child 12 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, body temperature increased. Zonisamide dosage: unknown. During the same period patient was treated with CLARITHROMYCIN, AGENT COMMON COLD. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5581055-8
Zonisamide side effect was reported by a Physician from JAPAN on Dec 11, 2007. Male patient, child 12 years of age, was diagnosed with epilepsy  and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, nasopharyngitis. Zonisamide dosage: unknown. During the same period patient was treated with CLARITHROMYCIN, AGENT COMMON COLD. Patient was hospitalized. Patient recovered.


Zonisamide Side Effects Report #4957769-7
Zonisamide side effect was reported by a Physician from JAPAN on Mar 16, 2006. Female patient, 43 years of age, was diagnosed with depressed level of consciousness, head injury and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal, thrombocytopenia. Zonisamide dosage: 200 MG, 1 IN 1 D; ORAL. During the same period patient was treated with PASIL, CEREB. Patient recovered.

Zonisamide Side Effects Report #4961261-3
Zonisamide side effect was reported by a Physician from JAPAN on Mar 16, 2006. Female patient, 65 years of age, was diagnosed with convulsion and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, erythema, mucosal haemorrhage, pharynx discomfort, pruritus, swelling face. Zonisamide dosage: 100 MG, ORAL. During the same period patient was treated with DEPAS, LOSARTAN POTASSIUM. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4975378-0
Zonisamide side effect was reported by a Physician from JAPAN on Mar 30, 2006. Female patient, 65 years of age, was diagnosed with convulsion and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal. Zonisamide dosage: unknown. During the same period patient was treated with DEPAS, LOSARTAN POTASSIUM. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #4968605-7
Zonisamide side effect was reported by a Physician from JAPAN on Mar 28, 2006. Female patient, 42 years of age, was diagnosed with convulsion, depressed level of consciousness and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, hepatic function abnormal, thrombocytopenia, viral infection . Zonisamide dosage: 200 MG, 1 IN 1 D, ORAL. During the same period patient was treated with PASIL, CEREB. Patient recovered.

Zonisamide Side Effects Report #5330588-8
Zonisamide side effect was reported by a Physician from JAPAN on May 08, 2007. Male patient, 23 years of age, was diagnosed with convulsion and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, dermatitis exfoliative, epilepsy , headache , infectious mononucleosis , liver disorder. Zonisamide dosage: unknown. During the same period patient was treated with FLOMOX, LEVOFLOXACIN. Patient was hospitalized. Patient recovered.


Zonisamide Side Effects Report #5523482-0
Zonisamide side effect was reported by a Health Professional from JAPAN on Nov 05, 2007. Male patient, 24 years of age, was diagnosed with aggression and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: aggression, agitation, aspartate aminotransferase increased, cerebral palsy, dyskinesia, dysphagia. Zonisamide dosage: 160 MG ; 300 MG ; 600 MG. During the same period patient was treated with CARBAMAZEPINE, RISPERIDONE, CLONAZEPAM. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5203869-6
Zonisamide side effect was reported by a Health Professional from UNITED STATES on Dec 19, 2006. Female patient, 35 years of age, was treated with Zonisamide. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, blood chloride decreased, blood potassium decreased, coma, hepatic encephalopathy, hepatic function abnormal, intentional overdose. Zonisamide dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, CARBAMAZEPINE, TIZANIDINE, FENTANYL. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5144502-1
Zonisamide side effect was reported by a Physician from UNITED STATES on Oct 19, 2006. Female patient, 35 years of age, was treated with Zonisamide. After drug was administered, patient experienced the following side effects: ammonia increased, aspartate aminotransferase increased, carbon dioxide decreased, coma, no therapeutic response, overdose, pco2 decreased, po2 increased, prothrombin time prolonged. Zonisamide dosage: unknown. During the same period patient was treated with ACETAMINOPHEN, BUTALBITAL, CARBAMAZEPINE, TIZANIDINE, FENTANYL. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5080829-X
Zonisamide side effect was reported by a Physician from JAPAN on Aug 01, 2006. Female patient, 30 years of age, was treated with Zonisamide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, eosinophil percentage increased, gamma-glutamyltransferase increased, hepatic function abnormal, lymphadenopathy. Zonisamide dosage: unknown. Patient was hospitalized. Patient recovered.

Zonisamide Side Effects Report #5485023-6
Zonisamide side effect was reported by a Health Professional from JAPAN on Oct 05, 2007. Male patient, 24 years of age, was diagnosed with partial seizures and was treated with Zonisamide. After drug was administered, patient experienced the following side effects: abasia, aggression, agitation, aspartate aminotransferase increased, blood creatine phosphokinase increased, choreoathetosis, dysphagia, heart rate increased. Zonisamide dosage: 160 TO 300 MG/DAY. During the same period patient was treated with RISPERIDONE, CLONAZEPAM, CARBAMAZEPINE. Patient was hospitalized. Patient recovered.