Zoledronate and aseptic necrosis bone Patient Reports February 12, 2012

Zoledronate Side Effects Report #4672868-5
Zoledronate side effect was reported by a Physician from on May 14, 2005. Male patient, 45 years of age, was diagnosed with osteoporosis  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, impaired healing, sinusitis . Zoledronate dosage: 4 MG, ONCE A YEAR. During the same period patient was treated with CALCIUM GLUCONATE, VITAMIN D3, ACYCLOVIR, ISOCILLIN, URSO FALK, PANTOPRAZOLE, PREDNISOLONE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.

Zoledronate Side Effects Report #4685464-0
Zoledronate side effect was reported by a Physician from on June 01, 2005. Female patient was diagnosed with osteoporosis  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone. Zoledronate dosage: unknown. Patient recovered.

Zoledronate Side Effects Report #4744229-1
Zoledronate side effect was reported by a Physician from UNITED STATES on June 21, 2005. Female patient, 67 years of age, was diagnosed with multiple myeloma  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone debridement, bone disorder, bone erosion, bone infection, bone scan abnormal, fistula , impaired healing, incisional drainage. Zoledronate dosage: 4 MG MONTHLY. During the same period patient was treated with DEXAMETHASONE. Patient recovered.

Zoledronate Side Effects Report #4704094-5
Zoledronate side effect was reported by a Physician from on June 21, 2005. Female patient, 65 years of age, was diagnosed with multiple myeloma  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone debridement, bone disorder, bone erosion, bone scan abnormal, impaired healing, incisional drainage, mouth ulceration, oral pain. Zoledronate dosage: 4 MG, QMO. During the same period patient was treated with DEXAMETHASONE. Patient recovered.


Zoledronate Side Effects Report #4668491-9
Zoledronate side effect was reported by a Health Professional from on June 15, 2004. Female patient, 53 years of age, was diagnosed with multiple myeloma  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone debridement, bone disorder, bone lesion, gingivitis, haemorrhage, mucosal inflammation, primary sequestrum. Zoledronate dosage: 4 MG, 28 DAYS. During the same period patient was treated with THALIDOMIDE, DEXAMETASON. Patient recovered.

Zoledronate Side Effects Report #4714915-8
Zoledronate side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 07, 2005. Female patient, 45 years of age, was diagnosed with multiple myeloma  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone disorder, malignant neoplasm progression, multiple myeloma , tooth extraction. Zoledronate dosage: 4 MG MONTHLY. During the same period patient was treated with DECADRON, AREDIA. Patient died on 02/04/2005.

Zoledronate Side Effects Report #4756606-3
Zoledronate side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 07, 2005. Female patient, 45 years of age, was diagnosed with multiple myeloma  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone disorder, malignant neoplasm progression, tooth extraction. Zoledronate dosage: 4 MG MONTHLY. During the same period patient was treated with DECADRON, AREDIA. Patient died on 01/31/2005.

Zoledronate Side Effects Report #4668683-9
Zoledronate side effect was reported by a Consumer or non-health professional from on Mar 29, 2005. Female patient, 74 years of age, was diagnosed with metastases to bone, breast cancer metastatic, hypothyroidism, asthma , cardiac disorder, insomnia, pain , arthritis  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, dental treatment, gingival bleeding, pain in jaw, periodontitis, wound debridement. Zoledronate dosage: 4 MG, QMO. During the same period patient was treated with FEMARA, SYNTHROID, FLOVENT, ASPIRIN, AMBIEN, ULTRACET, NAPROXEN, SEREVENT. Patient recovered.

Zoledronate Side Effects Report #4746089-1
Zoledronate side effect was reported by a Physician from ITALY on Aug 05, 2005. Female patient, 70 years of age, weighting 152.1 lb, was diagnosed with metastases to bone and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone pain, dental cleaning, dental operation, gingival infection, hyperaemia, local swelling, lymphadenopathy, medical device removal. Zoledronate dosage: 4 MG, QMO. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, FLUOROURACIL. Patient recovered.


Zoledronate Side Effects Report #4760302-6
Zoledronate side effect was reported by a Physician from AUSTRALIA on Aug 22, 2005. Male patient, 70 years of age, was diagnosed with metastases to bone, prostate cancer  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, discomfort, gingival pain. Zoledronate dosage: 4 MG, Q3MO. During the same period patient was treated with LUCRIN. Patient recovered.

Zoledronate Side Effects Report #4772010-6
Zoledronate side effect was reported by a Physician from ITALY on Aug 05, 2005. Female patient, 70 years of age, weighting 152.1 lb, was diagnosed with metastases to bone and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone pain, dental cleaning, dental operation, gingival infection, hyperaemia, local swelling, lymphadenopathy, medical device removal. Zoledronate dosage: 4 MG, QMO. During the same period patient was treated with CYCLOPHOSPHAMIDE, METHOTREXATE, FLUOROURACIL. Patient recovered.

Zoledronate Side Effects Report #4668252-0
Zoledronate side effect was reported by a Physician from on Apr 01, 2005. Female patient, 68 years of age, weighting 180.8 lb, was diagnosed with metastases to bone and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, jaw disorder, malignant neoplasm progression, osteonecrosis , tooth abscess. Zoledronate dosage: 4 MG EVERY 4 WEEKS. Patient recovered.

Zoledronate Side Effects Report #4750443-1
Zoledronate side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 14, 2005. Female patient, 59 years of age, was diagnosed with metastases to bone, breast cancer  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone graft , gingival erosion. Zoledronate dosage: 4 MG EVEY 6 MONTHS. During the same period patient was treated with FEMARA. Patient recovered.

Zoledronate Side Effects Report #4649798-8
Zoledronate side effect was reported by a Physician from on Apr 06, 2005. Female patient, 48 years of age, weighting 167.6 lb, was diagnosed with breast cancer  and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, gingival infection, tooth extraction, tooth infection. Zoledronate dosage: 4 MG, UNK. During the same period patient was treated with NOLVADEX, ZOLADEX. Patient recovered.


Zoledronate Side Effects Report #4770180-7
Zoledronate side effect was reported by a Health Professional from GERMANY on Sept 01, 2005. Male patient, 69 years of age, was diagnosed with myelodysplastic syndrome and was treated with Zoledronate. After drug was administered, patient experienced the following side effects: actinomycosis, aseptic necrosis bone, bone trimming, impaired healing, lip and/or oral cavity cancer, osteomyelitis chronic, osteonecrosis , plastic surgery, wound debridement. Zoledronate dosage: unknown. During the same period patient was treated with PAMIDRONATE DI. Patient recovered.

Zoledronate Side Effects Report #4763793-X
Zoledronate side effect was reported by a Physician from UNITED STATES on Aug 29, 2005. Female patient, 30 years of age, was treated with Zoledronate. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, osteonecrosis . Zoledronate dosage: unknown. Patient recovered.