Zevalin and multi-organ failure 
Zevalin and multi-organ failure Patient Reports February 12, 2012
Zevalin Side Effects Report #6122309-6
Zevalin side effect was reported by a Physician from SPAIN on Mar 13, 2009. Male patient, 60 years of age, weighting 163.1 lb, was diagnosed with stem cell transplant, b-cell lymphoma, prophylaxis against graft versus host disease and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute respiratory failure, catheter related infection, cytomegalovirus colitis, cytomegalovirus infection
, hepatic function abnormal, multi-organ failure, pancytopenia, pseudomonal bacteraemia, pyrexia. Zevalin dosage: unknown. During the same period patient was treated with YTRACIS, FLUDARABINE PHOSPHATE, RITUXIMAB, MELPHALAN, THIOTEPA, PREDNISONE. Patient was hospitalized. Patient died on 02/26/2009.Zevalin Side Effects Report #5920179-X
Zevalin side effect was reported by a Physician from SPAIN on Oct 09, 2008. Male patient, 58 years of age, weighting 123.5 lb, was diagnosed with non-hodgkin's lymphoma, thrombosis prophylaxis, prophylaxis against gastrointestinal ulcer, graft versus host disease and was treated with Zevalin. After drug was administered, patient experienced the following side effects: aspergillosis, cytomegalovirus colitis, graft versus host disease, multi-organ failure, sepsis
, septic shock. Zevalin dosage: unknown. During the same period patient was treated with YTRACIS, RITUXIMAB, FLUDARABINE PHOSPHATE, MELPHALAN, FRAXIPARINE, OMEPRAZOLE, METHYLPREDNISOLONE. Patient died on 10/01/2008.Zevalin Side Effects Report #5921769-0
Zevalin side effect was reported by a Physician from SPAIN on Oct 09, 2008. Male patient, 58 years of age, weighting 123.5 lb, was diagnosed with non-hodgkin's lymphoma, thrombosis prophylaxis, prophylaxis against gastrointestinal ulcer, graft versus host disease and was treated with Zevalin. After drug was administered, patient experienced the following side effects: aspergillosis, cytomegalovirus colitis, graft versus host disease, multi-organ failure, sepsis
, septic shock. Zevalin dosage: unknown. During the same period patient was treated with YTRACIS, RITUXIMAB, FLUDARABINE PHOSPHATE, MELPHALAN, FRAXIPARINE, OMEPRAZOLE, METHYLPREDNISOLONE. Patient died on 10/01/2008.Zevalin Side Effects Report #6112241-6
Zevalin side effect was reported by a Health Professional from SPAIN on Feb 26, 2009. Male patient, 58 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute graft versus host disease, aspergillosis, complications of transplant surgery, cytomegalovirus colitis, hypoxia, multi-organ failure, neutropenia, septic shock. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, FLUDARABINE PHOSPHATE, MELPHALAN, FRAXIPARINE, OMEPRAZOLE, METHYLPREDNISOLONE, GANCICLOVIR, AMBISOME. Patient died on 10/01/2008.
Zevalin Side Effects Report #4546713-2
Zevalin side effect was reported by a Consumer or non-health professional from on Dec 27, 2004. Male patient, 56 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: febrile neutropenia, intervertebral disc protrusion, multi-organ failure, pancytopenia, renal failure, sepsis
. Zevalin dosage: 500 MG; 1X; IV; 1200 MBQ;1X; IV. During the same period patient was treated with CEFTRIAXONE, CLINDAMYCIN, HYDROCHLORIDE, FILGRASTIM, LEVOFLOXACIN, FLUCONAZOLE. Patient was hospitalized. Patient died on 10/08/2004.Zevalin Side Effects Report #4662307-2
Zevalin side effect was reported by a Physician from on May 02, 2005. Male patient, 56 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: febrile neutropenia, intervertebral disc protrusion, malignant neoplasm progression, multi-organ failure, pancytopenia, renal failure, sepsis
. Zevalin dosage: unknown. During the same period patient was treated with CEFTRIAXONE, CLINDAMYCIN HYDROCHLORIDE, FILGRASTIM, LEVOFLOXACIN, FLUCONAZOLE. Patient was hospitalized. Patient died on 10/08/2004.Zevalin Side Effects Report #5301116-8
Zevalin side effect was reported by a Health Professional from ISRAEL on Aug 03, 2004. Male patient, 55 years of age, weighting 158.7 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute myocardial infarction, atrial fibrillation
, haemodialysis, hypotension, multi-organ failure, nervous system disorder, renal failure acute. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, TAMBOCOR. Patient was hospitalized. Patient died on 06/27/2004.Zevalin Side Effects Report #5055436-5
Zevalin side effect was reported by a Health Professional from GERMANY on June 28, 2006. Female patient, 63 years of age, weighting 350.5 lb, was diagnosed with central nervous system lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, asthenia, blood glucose abnormal, leukopenia, multi-organ failure, neutropenia, neutrophilia, pancytopenia. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, FORTECORTIN, CARMEN, COSAAR PLUS, PANTOZOL, VITAMIN B CAP, AMPHO. Patient was hospitalized. Patient died on 04/22/2006.
Zevalin Side Effects Report #5091488-4
Zevalin side effect was reported by a Consumer or non-health professional from GERMANY on Aug 15, 2006. Female patient, 63 years of age, weighting 350.5 lb, was diagnosed with central nervous system lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, asthenia, blood glucose increased, multi-organ failure, neutropenia, pancytopenia, pneumonia
, sepsis . Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, FORTECORTIN, CARMEN, COSAAR PLUS, PANTOZOL, VITAMIN B CAP, AMPHO. Patient was hospitalized. Patient died on 04/22/2006.Zevalin Side Effects Report #6138749-5
Zevalin side effect was reported by a Health Professional from SPAIN on Mar 13, 2009. Male patient, 59 years of age, was diagnosed with b-cell small lymphocytic lymphoma, stem cell transplant and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute respiratory failure, catheter related infection, cytomegalovirus infection
, enterococcal infection, hepatic function abnormal, multi-organ failure, oedema, pancytopenia, pseudomonas infection. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, FLUDARABINE PHOSPHATE, MELPHALAN, THIOTEPA, MYCOPHENOLATE MOFETIL, CYCLOSPORINE, ITRACONAZOLE. Patient was hospitalized. Patient died on 02/26/2009.Zevalin Side Effects Report #5835210-X
Zevalin side effect was reported by a Health Professional from FRANCE on July 21, 2008. Female patient, 62 years of age, was diagnosed with b-cell lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: blood creatine phosphokinase increased, blood creatinine increased, blood urea increased, multi-organ failure, troponin increased. Zevalin dosage: unknown. During the same period patient was treated with MABTHERA, BCNU, ARACYTINE, ETOPOSIDE, ALKERAN. Patient was hospitalized. Patient recovered.
Zevalin Side Effects Report #6099488-2
Zevalin side effect was reported by a Physician from SPAIN on Feb 26, 2009. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with b-cell lymphoma, thrombosis prophylaxis, prophylaxis against gastrointestinal ulcer, cytomegalovirus colitis and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute graft versus host disease, aspergillosis, cytomegalovirus colitis, multi-organ failure, sepsis
, septic shock. Zevalin dosage: unknown. During the same period patient was treated with YTRACIS, RITUXIMAB, FLUDARABINE PHOSPHATE, MELPHALAN, FRAXIPARINE, OMEPRAZOLE, GANCICLOVIR. Patient died on 10/01/2008.Zevalin Side Effects Report #6103290-2
Zevalin side effect was reported by a Physician from SPAIN on Feb 26, 2009. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with b-cell lymphoma, thrombosis prophylaxis, prophylaxis against gastrointestinal ulcer, cytomegalovirus colitis and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute graft versus host disease, aspergillosis, cytomegalovirus colitis, multi-organ failure, sepsis
, septic shock. Zevalin dosage: unknown. During the same period patient was treated with YTRACIS, RITUXIMAB, FLUDARABINE PHOSPHATE, MELPHALAN, FRAXIPARINE, OMEPRAZOLE, GANCICLOVIR. Patient died on 10/01/2008.Zevalin Side Effects Report #6136219-1
Zevalin side effect was reported by a Physician from SPAIN on Mar 25, 2009. Male patient, 52 years of age, weighting 165.3 lb, was diagnosed with b-cell lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bronchopulmonary aspergillosis, diarrhoea, liver injury, mucosal inflammation, multi-organ failure, neutropenia. Zevalin dosage: unknown. During the same period patient was treated with YTRACIS, RITUXIMAB, FLUDARABINE PHOSPHATE, MELPHALAN, METHOTREXATE. Patient died on 03/17/2009.
Zevalin Side Effects Report #5601068-7
Zevalin side effect was reported by a Physician from ITALY on Jan 04, 2008. Female patient was diagnosed with b-cell lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: cardiac failure congestive, disease progression, febrile neutropenia, haematotoxicity, hepatic failure, hepatitis c
, herpes zoster, multi-organ failure, pneumonia bacterial. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, ANTIBIOTIC PROPHYLAXIS. Patient recovered.Zevalin Side Effects Report #5933661-6
Zevalin side effect was reported by a Health Professional from SPAIN on Oct 09, 2008. Male patient was diagnosed with b-cell lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: aspergillosis, cytomegalovirus colitis, graft versus host disease, hypoxia, multi-organ failure, neutropenia, septic shock, stem cell transplant, tachycardia. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, FLUDARABINE PHOSPHATE, MELPHALAN, FRAXIPARINE, OMEPRAZOLE, METHYLPREDNISOLONE, GANCICLOVIR, AMBISOME. Patient died on 10/01/2008.
Zevalin Side Effects Report #5244836-6
Zevalin side effect was reported by a Health Professional from CROATIA (local name: Hrvatska) on Feb 07, 2007. Female patient, 33 years of age, was treated with Zevalin. After drug was administered, patient experienced the following side effects: lung infection pseudomonal, multi-organ failure, no therapeutic response, pathogen resistance, respiratory failure. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, CARMUSTINE, ETOPOSIDE, CYTARABINE, MELPHALAN. Patient was hospitalized. Patient died on 02/06/2007.
Zevalin Side Effects Report #5255142-8
Zevalin side effect was reported by a Health Professional from CROATIA (local name: Hrvatska) on Feb 13, 2007. Female patient, 33 years of age, was treated with Zevalin. After drug was administered, patient experienced the following side effects: multi-organ failure, pneumonia
, pseudomonas infection, respiratory failure. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, CARMUSTINE, ETOPOSIDE, CYTARABINE, MELPHALAN. Patient was hospitalized. Patient died on 02/06/2007.