Zevalin and bone marrow failure Patient Reports February 12, 2012

Zevalin Side Effects Report #5176458-X
Zevalin side effect was reported by a Health Professional from NORWAY on Nov 21, 2006. Female patient, 63 years of age, weighting 196.2 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, bone marrow failure, diverticulum intestinal, haematuria, hypersensitivity, myelodysplastic syndrome. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, LEVOTHYROXINE, INSULIN, ACETAMINOPHEN, METFORMIN, CYCLOPHOSPHAMIDE W, DEXCHLORPHENIRAMINE. Patient was hospitalized and became disabled. Patient died on 10/07/2006.

Zevalin Side Effects Report #4866777-6
Zevalin side effect was reported by a Consumer or non-health professional from GERMANY on Dec 05, 2005. Female patient, 63 years of age, weighting 196.2 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, bone marrow failure, diverticulum intestinal, haematuria, hypersensitivity, oedema. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, LEVOTHYROXINE, INSULIN, PARACETAMOL, METFORMIN, CYCLOPHOSPHAMIDE W. Patient was hospitalized and became disabled. Patient recovered.

Zevalin Side Effects Report #5080826-4
Zevalin side effect was reported by a Health Professional from THAILAND on July 26, 2006. Female patient, 58 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, hepatitis . Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #5110824-3
Zevalin side effect was reported by a Consumer or non-health professional from THAILAND on Sept 05, 2006. Female patient, 58 years of age, was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, hepatitis . Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.


Zevalin Side Effects Report #5253791-4
Zevalin side effect was reported by a Consumer or non-health professional from GERMANY on Feb 08, 2007. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: blood blister, bone marrow failure, contusion, epistaxis, haemorrhage subcutaneous, petechiae, pyrexia, thrombocytopenia. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #5261423-4
Zevalin side effect was reported by a Health Professional from GERMANY on Feb 20, 2007. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: blood blister, bone marrow failure, epistaxis, treatment noncompliance. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #5262005-0
Zevalin side effect was reported by a Health Professional from GERMANY on Feb 20, 2007. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: blood blister, bone marrow failure, bone marrow toxicity, macrocytosis, mucosal haemorrhage, neutropenia, oral mucosal blistering, red blood cell count decreased, thrombocytopenia. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #5298285-5
Zevalin side effect was reported by a Health Professional from UNITED KINGDOM on Mar 23, 2007. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: blood blister, bone marrow failure, contusion, epistaxis, haemorrhage, infection , macrocytosis, mucosal haemorrhage. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #5394946-8
Zevalin side effect was reported by a Health Professional from GERMANY on July 05, 2007. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, contusion, epistaxis, leukopenia, lip disorder, neutropenia, oral mucosal blistering, petechiae, thrombocytopenia. Zevalin dosage: unknown. During the same period patient was treated with RITUXAN. Patient was hospitalized. Patient recovered.


Zevalin Side Effects Report #4896999-X
Zevalin side effect was reported by a Health Professional from GERMANY on Jan 11, 2006. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: blood blister, bone marrow failure, contusion, epistaxis, neutropenia, petechiae. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #4897057-0
Zevalin side effect was reported by a Consumer or non-health professional from GERMANY on Jan 12, 2006. Female patient was diagnosed with non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: blood blister, bone marrow failure, contusion, epistaxis, mucosal haemorrhage, oral mucosal blistering, petechiae, pyrexia. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #6088770-0
Zevalin side effect was reported by a Health Professional from JAPAN on Feb 04, 2009. Male patient, 61 years of age, was diagnosed with mantle cell lymphoma stage iv and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, nausea , pyrexia. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, POLARAMINE, BAKTAR, BARACLUDE, OMEPRAL, FLUDARA, FLUDEOXYGLUCOSE. Patient recovered.

Zevalin Side Effects Report #6138748-3
Zevalin side effect was reported by a Health Professional from JAPAN on Mar 12, 2009. Male patient was diagnosed with mantle cell lymphoma stage iv and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, condition aggravated, nausea , pyrexia, sepsis . Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, POLARAMINE, BAKTAR, BARACLUDE, OMEPRAL, FLUDARA, FLUDEOXYGLUCOSE. Patient died.

Zevalin Side Effects Report #5911879-6
Zevalin side effect was reported by a Health Professional from ITALY on Sept 18, 2008. Female patient, 68 years of age, was diagnosed with central nervous system lymphoma, neoplasm recurrence and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, nausea . Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, CORTICOSTEROIDS, TEMOZOLOMIDE, METHOTREXATE. Patient recovered.


Zevalin Side Effects Report #5911876-0
Zevalin side effect was reported by a Health Professional from ITALY on Sept 18, 2008. Female patient, 51 years of age, was diagnosed with central nervous system lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, TEMOZOLOMIDE, METHOTREXATE, CYTARABINE, CORTICOSTEROIDS. Patient recovered.

Zevalin Side Effects Report #4845817-4
Zevalin side effect was reported by a Health Professional from FRANCE on Nov 15, 2005. Male patient, 47 years of age, weighting 202.8 lb, was diagnosed with bone marrow conditioning regimen, non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, bone marrow toxicity, stem cell transplant. Zevalin dosage: unknown. During the same period patient was treated with ACYCLOVIR, CASPOFUNGIN, AMPHOTERICIN B, HEPARIN, PANTOPRAZOLE, MORPHINE, NEFOPAM. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #4847579-3
Zevalin side effect was reported by a Health Professional from FRANCE on Nov 18, 2005. Male patient, 47 years of age, weighting 202.8 lb, was diagnosed with bone marrow conditioning regimen, non-hodgkin's lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, neutropenia, stem cell transplant. Zevalin dosage: unknown. During the same period patient was treated with ACYCLOVIR, CASPOFUNGIN, AMPHOTERICIN B, HEPARIN, PANTOPRAZOLE, MORPHINE, NEFOPAM. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #5063497-2
Zevalin side effect was reported by a Health Professional from FRANCE on July 06, 2006. Female patient, 44 years of age, weighting 198.4 lb, was diagnosed with bone marrow conditioning regimen and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, haemodialysis, renal failure acute, stem cell transplant. Zevalin dosage: unknown. During the same period patient was treated with RITUXIMAB, CARMUSTINE, ETOPOSIDE, ARACYTINE, MELPHALAN, ALIZAPRIDE, BENZNIDAZOLE, TRAMADOL. Patient was hospitalized. Patient recovered.

Zevalin Side Effects Report #5383599-0
Zevalin side effect was reported by a Health Professional from FINLAND on June 21, 2007. Female patient, 59 years of age, was diagnosed with b-cell lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure. Zevalin dosage: unknown. During the same period patient was treated with PANTOPRAZOLE, IBUMAX, PRIMPERAN, KYTRIL. Patient recovered.


Zevalin Side Effects Report #5391797-5
Zevalin side effect was reported by a Health Professional from FINLAND on July 05, 2007. Female patient, 59 years of age, was diagnosed with b-cell lymphoma and was treated with Zevalin. After drug was administered, patient experienced the following side effects: bone marrow failure, thrombosis. Zevalin dosage: unknown. During the same period patient was treated with RITUXAN, PANTOPRAZOLE, IBUMAX, PRIMPERAN, KYTRIL. Patient recovered.