Zavesca and off label use Patient Reports February 11, 2012

Zavesca Side Effects Report #4652631-1
Zavesca side effect was reported by a Health Professional from on Apr 16, 2005. Female patient, child 9 years of age, was diagnosed with tay-sachs disease and was treated with Zavesca. After drug was administered, patient experienced the following side effects: femur fracture, off label use. Zavesca dosage: unknown. Patient recovered.

Zavesca Side Effects Report #4840016-4
Zavesca side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Nov 15, 2005. Female patient, child 7 years of age, was diagnosed with niemann-pick disease and was treated with Zavesca. After drug was administered, patient experienced the following side effects: diarrhoea, injury asphyxiation, off label use, respiratory tract infection. Zavesca dosage: 100 MG, BID, ORAL. During the same period patient was treated with IMODIUM, LOMOTIL, AUGMENTIN. Patient died on 02/26/2005.

Zavesca Side Effects Report #4650142-0
Zavesca side effect was reported by a Consumer or non-health professional from on Apr 12, 2005. Female patient, child 3 years of age, weighting 22.49 lb, was diagnosed with gaucher's disease and was treated with Zavesca. After drug was administered, patient experienced the following side effects: abdominal distension, deafness, diarrhoea, dysphagia, gastrointestinal hypermotility, off label use, procedural complication, speech disorder developmental. Zavesca dosage: unknown. Patient recovered.

Zavesca Side Effects Report #5776266-2
Zavesca side effect was reported by a Consumer or non-health professional from UNITED STATES on May 30, 2008. Female patient, child 12 years of age, was diagnosed with gaucher's disease and was treated with Zavesca. After drug was administered, patient experienced the following side effects: abasia, disease progression, intestinal perforation, muscular weakness, off label use, progressive muscular atrophy, repair of imperforate rectum, tremor. Zavesca dosage: unknown. Patient recovered.