Zactima and asthenia Patient Reports February 12, 2012

Zactima Side Effects Report #6000210-6
Zactima side effect was reported by a Health Professional from UNITED STATES on Dec 11, 2008. Male patient, weighting 141.3 lb, was diagnosed with glioblastoma multiforme and was treated with Zactima. After drug was administered, patient experienced the following side effects: asthenia, disease progression, peripheral motor neuropathy. Zactima dosage: 300MG QD DAILY X 28 DAYS PO. During the same period patient was treated with GLEEVEC, HYDREA, LAMICTAL, KEPPRA, VALTREX, COLACE, METAMUCIL, DECADRON. Patient was hospitalized. Patient recovered.

Zactima Side Effects Report #6003586-9
Zactima side effect was reported by a Health Professional from UNITED STATES on Dec 12, 2008. Male patient, weighting 141.3 lb, was diagnosed with glioblastoma multiforme and was treated with Zactima. After drug was administered, patient experienced the following side effects: asthenia, disease progression, peripheral motor neuropathy. Zactima dosage: 300MG QD DAILY X 28 DAYS PO. During the same period patient was treated with GLEEVEC, HYDREA, LAMICTAL, KEPPRA, VALTREX, COLACE, METAMUCIL, DECADRON. Patient was hospitalized. Patient recovered.

Zactima Side Effects Report #6023453-4
Zactima side effect was reported by a Health Professional from UNITED STATES on Dec 26, 2008. Male patient, weighting 141.3 lb, was diagnosed with glioblastoma multiforme and was treated with Zactima. After drug was administered, patient experienced the following side effects: asthenia, disease progression, neurological decompensation, peripheral motor neuropathy. Zactima dosage: 300MG QD DAILY X 28 DAYS PO. During the same period patient was treated with HYDREA, GLEEVEC, LAMICTAL, KEPPRA, VALTREX, COLACE, METAMUCIL, DECADRON. Patient died on 12/20/2008.