Yondelis and bone marrow failure Patient Reports February 12, 2012

Yondelis Side Effects Report #5331004-2
Yondelis side effect was reported by a Physician from UNITED STATES on May 11, 2007. Female patient, weighting 138.0 lb, was diagnosed with ovarian cancer and was treated with Yondelis. After drug was administered, patient experienced the following side effects: arterial thrombosis limb, aspartate aminotransferase increased, blood glucose increased, bone marrow failure, bradycardia, cardiac arrest , catheter related infection, cough, dehydration. Yondelis dosage: unknown. During the same period patient was treated with DOXIL, PROTONIX, AMBIEN, MARINOL. Patient was hospitalized. Patient died on 03/21/2006.

Yondelis Side Effects Report #5511041-5
Yondelis side effect was reported by a Physician from UNITED STATES on Nov 02, 2007. Female patient, weighting 138.0 lb, was diagnosed with ovarian cancer and was treated with Yondelis. After drug was administered, patient experienced the following side effects: arterial thrombosis limb, bone marrow failure, bradycardia, cardiac arrest , catheter related infection, dehydration, disseminated intravascular coagulation, electromechanical dissociation, escherichia infection. Yondelis dosage: unknown. During the same period patient was treated with DOXIL, PROTONIX, AMBIEN, MARINOL. Patient was hospitalized. Patient died on 03/21/2006.

Yondelis Side Effects Report #4958142-8
Yondelis side effect was reported by a Physician from UNITED STATES on Mar 22, 2006. Female patient, weighting 138.0 lb, was diagnosed with ovarian cancer and was treated with Yondelis. After drug was administered, patient experienced the following side effects: blood sodium decreased, bone marrow failure, bradycardia, catheter related infection, dehydration, disseminated intravascular coagulation, electromechanical dissociation, haemorrhagic diathesis, hypocalcaemia. Yondelis dosage: unknown. During the same period patient was treated with DOXIL. Patient was hospitalized. Patient died on 03/21/2006.

Yondelis Side Effects Report #5511555-8
Yondelis side effect was reported by a Physician from CHINA on Oct 29, 2007. Female patient, weighting 149.9 lb, was diagnosed with ovarian cancer metastatic and was treated with Yondelis. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bone marrow failure, leukopenia, neutrophil count decreased. Yondelis dosage: unknown. During the same period patient was treated with DOXIL, ODANSETRON, NEUPOGEN. Patient was hospitalized. Patient recovered.


Yondelis Side Effects Report #5546714-1
Yondelis side effect was reported by a Physician from CHINA on Dec 03, 2007. Female patient, weighting 149.9 lb, was diagnosed with ovarian cancer metastatic and was treated with Yondelis. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bone marrow failure, leukopenia, neutrophil count decreased. Yondelis dosage: unknown. During the same period patient was treated with DOXIL, ODANSETRON, NEUPOGEN. Patient recovered.