Xigris and renal failure Patient Reports February 12, 2012

Xigris Side Effects Report #4801897-3
Xigris side effect was reported by a Pharmacist from UNITED STATES on Oct 14, 2005. Male patient, 51 years of age, weighting 171.1 lb, was diagnosed with systemic inflammatory response syndrome and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, culture stool positive, enterococcal infection, renal failure, respiratory failure, shock. Xigris dosage: unknown. During the same period patient was treated with DOBUTAMINE, VASOPRESSIN, NOREPINEPHRINE, PANTOPRAZOLE, PRIMAXIN, METRONIDAZOLE, FLUCONAZOLE, BICARBONATE. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5105895-4
Xigris side effect was reported by a Physician from UNITED STATES on Aug 24, 2006. Female patient, 65 years of age, was diagnosed with splenectomy and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemoglobin decreased, haemorrhage, renal failure. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5966098-4
Xigris side effect was reported by a Physician from ITALY on Nov 12, 2008. Male patient, 66 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: catheter site haemorrhage, gastrointestinal haemorrhage, post procedural haemorrhage, renal failure, respiratory failure. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, ANTIBIOTICS, IMMUNOSUPPRESSIVE AGENTS, CORTICOSTEROID NOS. Patient recovered.

Xigris Side Effects Report #5756984-2
Xigris side effect was reported by a Physician from CANADA on May 23, 2008. Female patient, weighting 224.9 lb, was diagnosed with septic shock, blood pressure decreased, endotracheal intubation and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac fibrillation, disseminated intravascular coagulation, haemoglobin decreased, international normalised ratio increased, neutropenia, pneumonia staphylococcal, renal failure, septic shock, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSIN, PROPOFOL, FENTANYL, HEPARIN. Patient died on 04/16/2008.


Xigris Side Effects Report #5514608-3
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 02, 2007. Female patient, 75 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: platelet count decreased, renal failure. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5322139-9
Xigris side effect was reported by a Physician from GERMANY on May 08, 2007. Male patient, 70 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: hepatic failure, renal failure, respiratory failure, sepsis . Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4898662-8
Xigris side effect was reported by a Pharmacist from UNITED STATES on Jan 11, 2006. Male patient, 70 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: hypotension, renal failure, respiratory failure. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient died on 01/05/2006.

Xigris Side Effects Report #4827613-7
Xigris side effect was reported by a Physician from UNITED STATES on Nov 01, 2005. Male patient, 69 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , catheter related complication, dialysis , pericardial effusion, renal failure. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4832393-5
Xigris side effect was reported by a Physician from UNITED STATES on Nov 01, 2005. Male patient, 69 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , catheter related complication, dialysis , pericardial haemorrhage, renal failure. Xigris dosage: unknown. Patient died.


Xigris Side Effects Report #4833372-4
Xigris side effect was reported by a Physician from UNITED STATES on Nov 07, 2005. Male patient, 69 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , dialysis , procedural complication, renal failure. Xigris dosage: unknown. Patient died on 02/13/2005.

Xigris Side Effects Report #5493470-1
Xigris side effect was reported by a Physician from UNITED STATES on Oct 10, 2007. Male patient, 64 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: catheter site haemorrhage, renal failure, wound haemorrhage. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4815826-X
Xigris side effect was reported by a Pharmacist from UNITED STATES on Oct 10, 2005. Male patient, 61 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemoglobin abnormal, haemorrhage, platelet count abnormal, renal failure. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4821516-X
Xigris side effect was reported by a Physician from UNITED STATES on Oct 17, 2005. Male patient, 61 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, dialysis , haemoglobin decreased, operative haemorrhage, renal failure, wound haemorrhage. Xigris dosage: unknown. During the same period patient was treated with CIPROFLOXACIN, CLINDAMYCIN, CEFTRIAXONE, DOPAMINE, MIDAZOLAM, NOREPINEPHRINE, INSULIN, PANTOPRAZOLE. Patient recovered.

Xigris Side Effects Report #5015414-9
Xigris side effect was reported by a Pharmacist from UNITED STATES on May 30, 2006. Male patient, 59 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood lactic acid increased, bradycardia, haemorrhage, hypokalaemia, post procedural complication, renal failure, sedation. Xigris dosage: unknown. Patient recovered.


Xigris Side Effects Report #4713951-5
Xigris side effect was reported by a Physician from UNITED KINGDOM on June 24, 2005. Female patient, 57 years of age, weighting 132.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemodialysis, haemorrhage intracranial, mouth haemorrhage, multi-organ failure, oesophageal haemorrhage, renal failure, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with FENTANYL, PROPOFOL, NORADRENALINE, CLARITHROMYCIN, CEFOTAXIME, FLOLAN, ACYCLOVIR. Patient was hospitalized. Patient died on 11/18/2004.

Xigris Side Effects Report #5205627-5
Xigris side effect was reported by a Physician from UNITED STATES on Jan 08, 2007. Female patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: azotaemia, fall , metabolic acidosis, renal failure, rhabdomyolysis, septic shock. Xigris dosage: unknown. Patient died on 11/30/2006.

Xigris Side Effects Report #5531387-4
Xigris side effect was reported by a Physician from GERMANY on Sept 28, 2007. Male patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, condition aggravated, multi-organ failure, pneumonia , renal failure, respiratory failure, sepsis , shock. Xigris dosage: unknown. During the same period patient was treated with TAVANIC, TAZOBACTAM, NORADRENALIN. Patient died on 07/14/2007.

Xigris Side Effects Report #5263909-5
Xigris side effect was reported by a Physician from AUSTRALIA on Feb 26, 2007. Male patient, 50 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: colonic polyp , diabetes mellitus, disorientation, hepatitis cholestatic, pyrexia, renal failure. Xigris dosage: unknown. During the same period patient was treated with VANCOMYCIN HYDROCHLORIDE, PENICILLIN G, CIPROFLOXACIN, CLINDAMYCIN, ANALGESICS, DIGOXIN, METHYLPREDNISOLONE. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4928192-6
Xigris side effect was reported by a Physician from GERMANY on Feb 03, 2006. Male patient, 15 years of age, weighting 154.3 lb, was diagnosed with meningococcal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: circulatory collapse, condition aggravated, meningococcal sepsis, multi-organ failure, renal failure, respiratory failure. Xigris dosage: unknown. During the same period patient was treated with CLAFORAN, ARIVEN, NORADRENALINE, DORMICUM ROCHE, SUFENTA, HYDROCORTISONE, OMEPRAZOLE. Patient was hospitalized. Patient died on 01/29/2006.


Xigris Side Effects Report #5211960-3
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 16, 2007. Male patient, 89 years of age, was diagnosed with lung injury and was treated with Xigris. After drug was administered, patient experienced the following side effects: dialysis , disease progression, haemodynamic instability, organ failure, renal failure, respiratory failure, sepsis . Xigris dosage: unknown. During the same period patient was treated with NIMBEX, FENTANYL TRANSDERMAL SYSTEM, MIDAZOLAM HYDROCHLORIDE, NOREPINEPHRINE BITARTRATE, VASOPRESSIN, DIFLUCIN, MEROPENEM. Patient died on 12/06/2006.

Xigris Side Effects Report #4746749-2
Xigris side effect was reported by a Health Professional from AUSTRALIA on Aug 01, 2005. Male patient, 57 years of age, weighting 242.5 lb, was diagnosed with intestinal perforation, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac failure, multi-organ failure, renal failure. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4776344-0
Xigris side effect was reported by a Health Professional from AUSTRALIA on Sept 01, 2005. Male patient, 57 years of age, weighting 242.5 lb, was diagnosed with intestinal perforation, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac failure, renal failure. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5140788-8
Xigris side effect was reported by a Physician from GERMANY on Oct 11, 2006. Female patient, 69 years of age, was diagnosed with infection  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiomyopathy , pulmonary vascular disorder, renal failure, shock, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with VANCOMYCIN, TAZOBAC. Patient died on 10/10/2006.

Xigris Side Effects Report #5141773-2
Xigris side effect was reported by a Physician from GERMANY on Oct 16, 2006. Female patient, 69 years of age, was diagnosed with infection  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , cardiomyopathy , nephritis, renal failure, sepsis , shock, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with VANCOMYCIN, TAZOBAC. Patient died on 10/10/2006.


Xigris Side Effects Report #4709623-3
Xigris side effect was reported by a Health Professional from UNITED STATES on June 29, 2005. Male patient, 85 years of age, was diagnosed with clostridial infection and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac disorder, dialysis , hypotension, organ failure, renal failure, respiratory failure. Xigris dosage: unknown. Patient died on 05/01/2005.

Xigris Side Effects Report #4713620-1
Xigris side effect was reported by a Health Professional from UNITED STATES on June 28, 2005. Male patient, 85 years of age, was diagnosed with clostridial infection and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac disorder, dialysis , hypotension, renal failure, respiratory failure. Xigris dosage: unknown. Patient died on 05/01/2005.

Xigris Side Effects Report #5716019-4
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 16, 2008. Male patient, 70 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: haemoglobin abnormal, renal failure, vomiting. Xigris dosage: unknown. During the same period patient was treated with INSULIN. Patient died on 10/17/2008.