Xigris and mydriasis Patient Reports February 12, 2012

Xigris Side Effects Report #5485635-X
Xigris side effect was reported by a Physician from GERMANY on Oct 04, 2007. Female patient, 76 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac failure, cerebral haemorrhage, mydriasis. Xigris dosage: 24 MG/KG/HOUR. Patient died on 09/25/2007.

Xigris Side Effects Report #5486382-0
Xigris side effect was reported by a Physician from GERMANY on Oct 04, 2007. Female patient, 76 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac failure, cerebral haemorrhage, mydriasis. Xigris dosage: 24 MG/KG/HOUR. Patient died on 09/25/2007.

Xigris Side Effects Report #4579462-5
Xigris side effect was reported by a Consumer or non-health professional from on Jan 19, 2005. Male patient, 65 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, depressed level of consciousness, hydrocephalus , international normalised ratio increased, intracranial pressure increased, mydriasis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient died on 12/25/2004.

Xigris Side Effects Report #4752541-5
Xigris side effect was reported by a Physician from BRAZIL on Aug 08, 2005. Female patient, 68 years of age, weighting 200.6 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haematoma, cerebrovascular accident, encephalopathy, intracranial pressure increased, mydriasis. Xigris dosage: 25 MG/Q12 HOUR. Patient was hospitalized. Patient died.


Xigris Side Effects Report #4759194-0
Xigris side effect was reported by a Consumer or non-health professional from INDIA on Aug 12, 2005. Male patient, 57 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: bradycardia, convulsion, haemorrhage intracranial, mydriasis. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5407398-6
Xigris side effect was reported by a Physician from UNITED STATES on Aug 01, 2007. Male patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: mydriasis. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5456417-X
Xigris side effect was reported by a Physician from UNITED STATES on Sept 13, 2007. Male patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: deposit eye, mydriasis. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4815032-9
Xigris side effect was reported by a Health Professional from INDIA on Oct 07, 2005. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time, activated partial thromboplastin time prolonged, blood creatinine increased, cerebral haemorrhage, international normalised ratio increased, loss of consciousness, mydriasis, peritoneal dialysis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with SEDATIVE, MUSCLE RELAXANT, ANTIBIOTIC. Patient was hospitalized. Patient died on 09/28/2005.

Xigris Side Effects Report #4822100-4
Xigris side effect was reported by a Consumer or non-health professional from INDIA on Oct 14, 2005. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood creatine increased, cerebral haemorrhage, international normalised ratio increased, loss of consciousness, mydriasis, peritoneal dialysis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with SEDATIVE, MUSCLE RELAXANT, ANTIBIOTIC. Patient was hospitalized. Patient died on 09/28/2005.


Xigris Side Effects Report #4546382-1
Xigris side effect was reported by a Health Professional from on Dec 09, 2004. Male patient, 49 years of age, weighting 209.4 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: bone disorder, brain oedema, haemodialysis, haemorrhage intracranial, hyperglycaemia, mydriasis, pancreatic necrosis, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, NORADRENALINE, DOPEXAMINE, PROPOFOL, ALFENTANIL, ACTRAPID, MEROPENEM, HYDROCORTISONE. Patient was hospitalized. Patient died on 09/25/2004.

Xigris Side Effects Report #6072267-8
Xigris side effect was reported by a Pharmacist from UNITED STATES on Feb 06, 2009. Female patient, 47 years of age, weighting 295.4 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: mydriasis, platelet count decreased, subarachnoid haemorrhage. Xigris dosage: 3.2 MG/HR IV DRIP. Patient died on 01/13/2009.

Xigris Side Effects Report #4704065-9
Xigris side effect was reported by a Physician from on June 09, 2005. Female patient, 45 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: laboratory test interference, mydriasis, white blood cell count decreased. Xigris dosage: unknown. During the same period patient was treated with VASOPRESSOR AGENTS. Patient recovered.

Xigris Side Effects Report #4752378-7
Xigris side effect was reported by a Physician from INDIA on Aug 08, 2005. Male patient, 40 years of age, weighting 154.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, brain oedema, haemorrhage intracranial, multi-organ failure, mydriasis, platelet count decreased, pupil fixed. Xigris dosage: unknown. During the same period patient was treated with ARTESUNATE, MEROPENEM, VANCOMYCIN, LASIX, NORADRENALINE, DOBUTAMINE, PANTOCID, FENTANYL. Patient died on 07/20/2005.

Xigris Side Effects Report #4777997-3
Xigris side effect was reported by a Consumer or non-health professional from INDIA on Sept 06, 2005. Male patient, 38 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, loss of consciousness, mydriasis, thrombosis. Xigris dosage: unknown. Patient was hospitalized. Patient died on 08/18/2005.


Xigris Side Effects Report #4802972-X
Xigris side effect was reported by a Physician from INDIA on Sept 25, 2005. Male patient, 14 years of age, weighting 88.18 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, mydriasis. Xigris dosage: 24 MG/KG/HR. During the same period patient was treated with CEFOPERAZONE, CLINDAMYCIN, MEROPENEM, HEPARIN. Patient was hospitalized. Patient died on 09/25/2005.

Xigris Side Effects Report #4831002-9
Xigris side effect was reported by a Consumer or non-health professional from INDIA on Oct 26, 2005. Male patient, 14 years of age, weighting 88.18 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood disorder, cardiovascular disorder, electroencephalogram abnormal, intracranial pressure increased, metabolic acidosis, multi-organ disorder, mydriasis, renal disorder, respiratory disorder. Xigris dosage: 24 MG/KG/HR. During the same period patient was treated with CEFOPERAZONE, CLINDAMYCIN, MEROPENEM, HEPARIN. Patient was hospitalized. Patient died on 09/25/2005.

Xigris Side Effects Report #4614152-1
Xigris side effect was reported by a Physician from on Feb 28, 2005. Female patient, 50 years of age, was diagnosed with pneumonia staphylococcal and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, intraventricular haemorrhage, mydriasis, peripheral ischaemia, platelet count decreased, pupil fixed. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, ENOXAPARIN, PROSTACYCLIN. Patient recovered.

Xigris Side Effects Report #5886217-8
Xigris side effect was reported by a Physician from CANADA on Sept 04, 2008. Male patient, 51 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: mydriasis. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4781680-8
Xigris side effect was reported by a Consumer or non-health professional from ICELAND on Sept 08, 2005. Female patient, 50 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: blood pressure increased, disseminated intravascular coagulation, multi-organ failure, mydriasis, nervous system disorder, pupillary reflex impaired. Xigris dosage: unknown. Patient recovered.