Xigris and multi-organ failure Patient Reports February 12, 2012

Xigris Side Effects Report #6077712-X
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 11, 2009. Female patient, 73 years of age, was diagnosed with urosepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Xigris dosage: unknown. Patient died on 11/11/2008.

Xigris Side Effects Report #4890573-7
Xigris side effect was reported by a Health Professional from UNITED STATES on Jan 06, 2006. Female patient, 56 years of age, was diagnosed with urosepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died on 12/24/2005.

Xigris Side Effects Report #5071736-7
Xigris side effect was reported by a Physician from GERMANY on July 14, 2006. Male patient was diagnosed with systemic inflammatory response syndrome and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, off label use. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5405152-2
Xigris side effect was reported by a Physician from MEXICO on July 19, 2007. Female patient, 48 years of age, was diagnosed with shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal sepsis, epistaxis, gastrointestinal haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MEROPENEM, OMEPRAZOLE, METRONIDAZOLE, AMINOPHYLLINE. Patient died on 06/17/2007.


Xigris Side Effects Report #5430524-X
Xigris side effect was reported by a Physician from MEXICO on Aug 20, 2007. Female patient, 48 years of age, was diagnosed with shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal sepsis, epistaxis, gastrointestinal haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MEROPENEM, OMEPRAZOLE, METRONIDAZOLE, AMINOPHYLLINE. Patient died on 06/17/2007.

Xigris Side Effects Report #4860691-8
Xigris side effect was reported by a Physician from UNITED STATES on Dec 02, 2005. Female patient, 68 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute myocardial infarction, multi-organ failure. Xigris dosage: unknown. Patient died on 11/01/2005.

Xigris Side Effects Report #5680230-1
Xigris side effect was reported by a Physician from FRANCE on Mar 14, 2008. Male patient, 61 years of age, weighting 251.3 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haematoma, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, NORADRENALINE, DOBUTREX, CLAFORAN, TAVANIC. Patient was hospitalized. Patient died on 02/25/2008.

Xigris Side Effects Report #5823481-5
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on July 17, 2008. Female patient, 60 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died on 05/28/2008.

Xigris Side Effects Report #5828726-3
Xigris side effect was reported by a Physician from UNITED STATES on July 23, 2008. Female patient, 60 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiopulmonary failure, multi-organ failure, septic shock. Xigris dosage: unknown. Patient died.


Xigris Side Effects Report #5232826-9
Xigris side effect was reported by a Pharmacist from UNITED STATES on Feb 06, 2007. Female patient, 59 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: anaemia, multi-organ failure, post procedural haemorrhage. Xigris dosage: unknown. Patient was hospitalized and became disabled. Patient recovered.

Xigris Side Effects Report #5022700-5
Xigris side effect was reported by a Consumer or non-health professional from FRANCE on May 22, 2006. Male patient, 53 years of age, weighting 194.0 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, epistaxis, meningorrhagia, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with ASPEGIC, HYDROCORTISONE, NIMBEX, INSULIN, PERFALGAN, ALPRAZOLAM, LIORESAL, EZETROL. Patient died on 01/30/2006.

Xigris Side Effects Report #5533520-7
Xigris side effect was reported by a Physician from CANADA on Nov 28, 2007. Male patient, 52 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died on 11/01/2007.

Xigris Side Effects Report #5407378-0
Xigris side effect was reported by a Physician from UNITED STATES on July 30, 2007. Female patient, 44 years of age, weighting 142.0 lb, was diagnosed with septic shock, prophylaxis and was treated with Xigris. After drug was administered, patient experienced the following side effects: deep vein thrombosis , multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with LOVENOX, LEVOPHED, VASOPRESSIN, COMBIVENT, ROCEPHIN, PEPCID, INSULIN, HYDROCORTISONE. Patient died on 04/24/2007.

Xigris Side Effects Report #5113947-8
Xigris side effect was reported by a Physician from AUSTRALIA on Aug 30, 2006. Female patient, 81 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with EPINEPHRINE, NORADRENALINE, VASOPRESSIN AND ANALOGUES. Patient died on 08/10/2006.


Xigris Side Effects Report #6101115-2
Xigris side effect was reported by a Physician from INDIA on Feb 27, 2009. Male patient, 80 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Xigris dosage: unknown. Patient was hospitalized. Patient died on 02/26/2009.

Xigris Side Effects Report #6128216-7
Xigris side effect was reported by a Physician from INDIA on Mar 17, 2009. Male patient, 80 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Xigris dosage: unknown. Patient was hospitalized. Patient died on 02/26/2009.

Xigris Side Effects Report #4565361-1
Xigris side effect was reported by a Pharmacist from on Jan 11, 2005. Male patient, 77 years of age, weighting 70.55 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute myocardial infarction, immunosuppression, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with CLINDAMYCIN, ROCEPHIN, VANCOMYCIN, DOPAMINE, MEROPENEM. Patient died on 11/02/2005.

Xigris Side Effects Report #4821814-X
Xigris side effect was reported by a Physician from UNITED KINGDOM on Oct 13, 2005. Female patient, 76 years of age, weighting 154.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, ACETAMINOPHEN, HYDROCORTISONE, ANTIBIOTIC. Patient died on 09/29/2005.

Xigris Side Effects Report #4608743-1
Xigris side effect was reported by a Consumer or non-health professional from on Feb 22, 2005. Male patient, 73 years of age, weighting 143.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute myocardial infarction, bacterial sepsis, confusional state, epistaxis, hydronephrosis, mouth haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE, CIPROFLOXACIN, NORADRENALINE. Patient recovered.


Xigris Side Effects Report #4870273-X
Xigris side effect was reported by a Physician from SPAIN on Nov 29, 2005. Male patient, 71 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal distension, coagulopathy, kaolin cephalin clotting time prolonged, multi-organ failure, peritoneal haemorrhage, splenic rupture. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5200040-9
Xigris side effect was reported by a Physician from UNITED STATES on Dec 27, 2006. Female patient, 70 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MORPHINE, PEPCID, LIDOCAINE, ATIVAN, ROCEPHIN, INSULIN, ZYVOX, LEVOPHED. Patient died on 12/28/2006.

Xigris Side Effects Report #5002907-3
Xigris side effect was reported by a Health Professional from UNITED STATES on Apr 28, 2006. Female patient, 68 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, post procedural haemorrhage. Xigris dosage: unknown. Patient died on 03/01/2006.

Xigris Side Effects Report #5197091-X
Xigris side effect was reported by a Physician from UNITED KINGDOM on Dec 22, 2006. Female patient, 66 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, multi-organ failure, septic shock. Xigris dosage: 9.7 ML, EVERY HOUR. During the same period patient was treated with ALFENTANIL, ATRACURIUM BESYLATE, CEFTRIAXONE, DOPEXAMINE, ENOXAPARIN, FLOLAN, HYDROCORTISONE, METRONIDAZOLE. Patient died on 11/30/2006.

Xigris Side Effects Report #5813511-9
Xigris side effect was reported by a Physician from UNITED STATES on July 07, 2008. Male patient, 66 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cystitis klebsiella, multi-organ failure, pneumonia , shock, staphylococcal bacteraemia, staphylococcal sepsis. Xigris dosage: unknown. During the same period patient was treated with ZOSYN, VANCOMYCIN HYDROCHLORIDE, FLAGYL, LINEZOLID. Patient was hospitalized. Patient died on 06/10/2008.


Xigris Side Effects Report #5346004-6
Xigris side effect was reported by a Physician from AUSTRALIA on May 30, 2007. Female patient, 61 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiogenic shock, cor pulmonale, hypovolaemic shock, multi-organ failure, septic shock. Xigris dosage: unknown. Patient was hospitalized. Patient died on 05/25/2007.

Xigris Side Effects Report #5349501-2
Xigris side effect was reported by a Physician from IRELAND on May 30, 2007. Female patient, 61 years of age, weighting 132.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, multi-organ failure, sepsis . Xigris dosage: 1.44 MG, EVERY HOUR. During the same period patient was treated with VENTOLIN, SPIRIVA, AMITRIPTYLINE, ZOLPIDEM TARTRATE. Patient died on 03/08/2007.

Xigris Side Effects Report #4562911-6
Xigris side effect was reported by a Health Professional from on Dec 30, 2004. Male patient, 61 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, multi-organ failure, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with HIGH DOSE VASOPRESSORS, METRONIDAZOLE. Patient recovered.

Xigris Side Effects Report #4949358-5
Xigris side effect was reported by a Pharmacist from UNITED STATES on Feb 23, 2006. Female patient, 61 years of age, weighting 330.0 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, international normalised ratio increased, multi-organ failure, platelet count decreased, sepsis . Xigris dosage: unknown. During the same period patient was treated with PROTONIX, HYDROCORTISONE, DIFLUCAN, LEVAQUINN, ZYVOX, BACTRIM, PRIMAXIN. Patient died.

Xigris Side Effects Report #4949921-1
Xigris side effect was reported by a Physician from UNITED STATES on Mar 02, 2006. Female patient, 61 years of age, weighting 205.0 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: brain oedema, disease progression, gastrointestinal haemorrhage, international normalised ratio abnormal, multi-organ failure, septic shock. Xigris dosage: unknown. Patient was hospitalized. Patient died on 11/17/2005.


Xigris Side Effects Report #5767290-4
Xigris side effect was reported by a Physician from UNITED STATES on June 02, 2008. Female patient, 60 years of age, was diagnosed with sepsis , pneumonia  and was treated with Xigris. After drug was administered, patient experienced the following side effects: malignant neoplasm progression, multi-organ failure, sepsis . Xigris dosage: unknown. During the same period patient was treated with ROCEPHIN, LEVAQUIN. Patient was hospitalized. Patient died on 05/01/2008.

Xigris Side Effects Report #5278060-8
Xigris side effect was reported by a Physician from UNITED STATES on Mar 20, 2007. Male patient, 58 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, multi-organ failure. Xigris dosage: unknown. Patient died on 03/08/2007.

Xigris Side Effects Report #4600093-2
Xigris side effect was reported by a Physician from on Feb 16, 2005. Male patient, 57 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with GLYCOPYRROLATE, VITAMIN K, LASIX, HYDROCORTISONE, NORADRENALINE, VASOPRESSOR, MOXIFLOXACIN, CIPROFLOXACIN. Patient was hospitalized. Patient died on 01/22/2005.

Xigris Side Effects Report #4713951-5
Xigris side effect was reported by a Physician from UNITED KINGDOM on June 24, 2005. Female patient, 57 years of age, weighting 132.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemodialysis, haemorrhage intracranial, mouth haemorrhage, multi-organ failure, oesophageal haemorrhage, renal failure, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with FENTANYL, PROPOFOL, NORADRENALINE, CLARITHROMYCIN, CEFOTAXIME, FLOLAN, ACYCLOVIR. Patient was hospitalized. Patient died on 11/18/2004.

Xigris Side Effects Report #5300636-X
Xigris side effect was reported by a Physician from ARGENTINA on Apr 03, 2007. Male patient, 56 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: 24 MG/KG, EVERY HOUR. Patient died on 02/28/2007.


Xigris Side Effects Report #4638245-8
Xigris side effect was reported by a Physician from on Mar 25, 2005. Female patient, 56 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: mouth haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with DOPAMINE, LEVOPHED, NEOSYNEPHRINE. Patient died on 02/16/2005.

Xigris Side Effects Report #5478571-6
Xigris side effect was reported by a Physician from GERMANY on Sept 28, 2007. Male patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with TAVANIC, TAZOBACTAM, NORADRENALIN. Patient died on 07/14/2007.

Xigris Side Effects Report #5507830-3
Xigris side effect was reported by a Physician from GERMANY on Nov 02, 2007. Male patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with TAVANIC, TAZOBACTAM, NORADRENALIN. Patient died on 07/14/2007.

Xigris Side Effects Report #5508519-7
Xigris side effect was reported by a Physician from GERMANY on Sept 26, 2007. Male patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with TAVANIC, TAZOBACTAM, NORADRENALIN. Patient died on 07/14/2007.

Xigris Side Effects Report #5528929-1
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 15, 2007. Male patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Xigris dosage: unknown. Patient died on 11/13/2007.


Xigris Side Effects Report #5531387-4
Xigris side effect was reported by a Physician from GERMANY on Sept 28, 2007. Male patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, condition aggravated, multi-organ failure, pneumonia , renal failure, respiratory failure, sepsis , shock. Xigris dosage: unknown. During the same period patient was treated with TAVANIC, TAZOBACTAM, NORADRENALIN. Patient died on 07/14/2007.

Xigris Side Effects Report #5653646-7
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 28, 2008. Female patient, 55 years of age, was diagnosed with sepsis , mechanical ventilation and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with OXYGEN. Patient died on 11/01/2007.

Xigris Side Effects Report #5197192-6
Xigris side effect was reported by a Physician from UNITED STATES on Dec 22, 2006. Male patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: convulsion, multi-organ failure. Xigris dosage: unknown. Patient died on 10/29/2006.

Xigris Side Effects Report #5052115-5
Xigris side effect was reported by a Physician from SPAIN on June 19, 2006. Male patient, 52 years of age, weighting 165.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal pain upper, cerebral haemorrhage, diabetes insipidus , hypotension, hypothermia , multi-organ failure, pneumonia , respiratory failure. Xigris dosage: unknown. During the same period patient was treated with MIDAZOLAM HYDROCHLORIDE, ANTIBIOTICS, CORTICOSTEROIDS, DOPAMINE, NORADRENALINE, PANTOPRAZOLE. Patient was hospitalized. Patient died on 04/01/2006.

Xigris Side Effects Report #5977818-7
Xigris side effect was reported by a Physician from UNITED STATES on Nov 26, 2008. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: anaemia, multi-organ failure, septic shock, thrombocytopenia. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5030002-6
Xigris side effect was reported by a Physician from SPAIN on May 26, 2006. Male patient, 52 years of age, weighting 165.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal pain upper, cerebral haemorrhage, diabetes insipidus , hypotension, hypothermia , multi-organ failure, nosocomial infection, pneumonia , respiratory failure. Xigris dosage: unknown. During the same period patient was treated with MIDAZOLAM, ANTIBIOTICS. Patient was hospitalized. Patient died on 04/01/2006.

Xigris Side Effects Report #4747035-7
Xigris side effect was reported by a Pharmacist from UNITED STATES on July 28, 2005. Male patient, 49 years of age, weighting 130.1 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiovascular disorder, metabolic acidosis, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with DOPAMINE, NOREPINEPHRINE, PHENYLEPHRINE, EPHEDRINE. Patient recovered.

Xigris Side Effects Report #4570794-3
Xigris side effect was reported by a Consumer or non-health professional from on Jan 14, 2005. Male patient, 47 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, septic shock. Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE, MORPHINE, FRUSEMIDE, BICARBONATE, THIAMINE, ZANTAC, VENTOLIN, ATROVENT. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4579516-3
Xigris side effect was reported by a Consumer or non-health professional from on Jan 21, 2005. Male patient, 47 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, septic shock. Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE, MORPHINE, FRUSEMIDE, BICARBONATE IN PLASTIC CONTAINER, THIAMINE, ZANTAC, VENTOLIN, ATROVENT. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4595869-4
Xigris side effect was reported by a Health Professional from on Feb 08, 2005. Male patient, 47 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, septic shock. Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE, MORPHINE, FRUSEMIDE, BICARBONATE, THIAMINE, ZANTAC, VENTOLIN, ATROVENT. Patient was hospitalized. Patient died on 01/09/2005.


Xigris Side Effects Report #5278041-4
Xigris side effect was reported by a Physician from GERMANY on Mar 20, 2007. Male patient, 45 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, multi-organ failure, sepsis , septic shock. Xigris dosage: 3.9 ML, EVERY HOUR. Patient died on 03/01/2007.

Xigris Side Effects Report #5284638-8
Xigris side effect was reported by a Physician from GERMANY on Mar 23, 2007. Male patient, 45 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis , septic shock. Xigris dosage: 3.9 ML, EVERY HOUR. Patient died on 03/01/2007.

Xigris Side Effects Report #6128217-9
Xigris side effect was reported by a Physician from INDIA on Mar 17, 2009. Male patient, 44 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Xigris dosage: unknown. Patient was hospitalized. Patient died on 02/17/2009.

Xigris Side Effects Report #4704453-0
Xigris side effect was reported by a Physician from on June 09, 2005. Male patient, 44 years of age, weighting 121.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, pulmonary tuberculosis. Xigris dosage: 1.4 MG/HR. During the same period patient was treated with PROPOFOL, ALFENTANIL, NORADRENALINE, PANTOPRAZOLE, METRONIDAZOLE, RIFAMPICIN, ISONIAZID. Patient was hospitalized. Patient died on 05/22/2005.

Xigris Side Effects Report #4656144-2
Xigris side effect was reported by a Physician from on Apr 18, 2005. Female patient, 43 years of age, weighting 218.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4662557-5
Xigris side effect was reported by a Physician from on Apr 26, 2005. Female patient, 43 years of age, weighting 218.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4625579-6
Xigris side effect was reported by a Physician from on Mar 11, 2005. Female patient, 41 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: atelectasis, condition aggravated, endocarditis , haematoma, haemothorax, left ventricular failure, multi-organ failure, petechiae, phlebothrombosis. Xigris dosage: unknown. Patient died on 03/09/2005.

Xigris Side Effects Report #4630263-9
Xigris side effect was reported by a Physician from on Mar 17, 2005. Female patient, 41 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac failure, chronic right ventricular failure, contusion, dilatation atrial, endocarditis , haematoma, haemothorax, multi-organ failure, muscle disorder . Xigris dosage: unknown. Patient died on 03/09/2005.

Xigris Side Effects Report #4692890-2
Xigris side effect was reported by a Consumer or non-health professional from on May 26, 2005. Male patient, 41 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, petechiae, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with VITAMIN K. Patient died on 05/26/2005.

Xigris Side Effects Report #4752378-7
Xigris side effect was reported by a Physician from INDIA on Aug 08, 2005. Male patient, 40 years of age, weighting 154.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, brain oedema, haemorrhage intracranial, multi-organ failure, mydriasis, platelet count decreased, pupil fixed. Xigris dosage: unknown. During the same period patient was treated with ARTESUNATE, MEROPENEM, VANCOMYCIN, LASIX, NORADRENALINE, DOBUTAMINE, PANTOCID, FENTANYL. Patient died on 07/20/2005.


Xigris Side Effects Report #5034299-8
Xigris side effect was reported by a Physician from UNITED KINGDOM on June 01, 2006. Female patient, 39 years of age, weighting 99.21 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: convulsion, disseminated intravascular coagulation, haemorrhagic fever, multi-organ failure, rectal haemorrhage, subarachnoid haemorrhage, vaginal haemorrhage. Xigris dosage: unknown. Patient died on 03/13/2006.

Xigris Side Effects Report #5411921-5
Xigris side effect was reported by a Physician from AUSTRALIA on Aug 06, 2007. Male patient, 35 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died on 07/01/2007.

Xigris Side Effects Report #4570795-5
Xigris side effect was reported by a Consumer or non-health professional from on Jan 14, 2005. Female patient, 34 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: 24 MG OTHER. During the same period patient was treated with ACTRAPID, ZANTAC, HYDROCORTISONE, LEVOPHED, ERYTHROMYCIN, MORPHINE, VASOPRESSINECTION, BICARBONATE. Patient was hospitalized. Patient died on 01/10/2005.

Xigris Side Effects Report #5400680-8
Xigris side effect was reported by a Physician from AUSTRALIA on July 19, 2007. Female patient, 32 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died on 07/01/2007.

Xigris Side Effects Report #4595423-4
Xigris side effect was reported by a Health Professional from on Feb 04, 2005. Female patient, 30 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, multi-organ failure. Xigris dosage: unknown. Patient died on 01/18/2005.

Xigris Side Effects Report #5871658-5
Xigris side effect was reported by a Physician from UNITED STATES on Aug 21, 2008. Female patient, 28 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, meningitis , multi-organ failure. Xigris dosage: unknown. Patient died on 03/01/2008.

Xigris Side Effects Report #5883885-1
Xigris side effect was reported by a Physician from UNITED STATES on Sept 02, 2008. Female patient, 28 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, multi-organ failure. Xigris dosage: unknown. Patient died on 03/01/2008.

Xigris Side Effects Report #4936371-7
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 13, 2006. Female patient, 21 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died on 02/01/2006.

Xigris Side Effects Report #5200049-5
Xigris side effect was reported by a Physician from UNITED STATES on Dec 28, 2006. Female patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: incision site haemorrhage, multi-organ failure, post procedural haemorrhage, sepsis . Xigris dosage: unknown. Patient died on 01/01/2006.

Xigris Side Effects Report #5278043-8
Xigris side effect was reported by a Physician from UNITED STATES on Mar 21, 2007. Male patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died on 03/01/2007.


Xigris Side Effects Report #5319981-7
Xigris side effect was reported by a Physician from UNITED STATES on May 01, 2007. Female patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, multi-organ failure. Xigris dosage: unknown. Patient died on 03/20/2007.

Xigris Side Effects Report #5360632-3
Xigris side effect was reported by a Physician from UNITED STATES on June 13, 2007. Female patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5496460-8
Xigris side effect was reported by a Physician from AUSTRALIA on Oct 12, 2007. Male patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4565393-3
Xigris side effect was reported by a Pharmacist from on Jan 19, 2005. Male patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE BITARTRATE, AMIODARONE, VASOPRESSINECTION. Patient died on 01/06/2005.

Xigris Side Effects Report #6033313-0
Xigris side effect was reported by a Physician from INDIA on Jan 05, 2009. Male patient, 89 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Xigris dosage: unknown. Patient was hospitalized. Patient died on 01/03/2009.

Xigris Side Effects Report #6133813-9
Xigris side effect was reported by a Physician from INDIA on Mar 19, 2009. Female patient, 77 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, platelet count decreased, sepsis . Xigris dosage: unknown. Patient was hospitalized. Patient died on 03/19/2009.

Xigris Side Effects Report #6119251-3
Xigris side effect was reported by a Physician from UNITED STATES on Mar 06, 2009. Male patient, 74 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with OXYGEN, ESOMEPRAZOLE, ALBUTEROL, ACETYLCYSTEINE, CALCIUM CHLORIDE, INSULIN REGULAR, MAGNESIUM SULPHATE, POTASSIUM CHLORIDE. Patient died on 12/22/2008.

Xigris Side Effects Report #4842644-9
Xigris side effect was reported by a Physician from UNITED STATES on Nov 11, 2005. Female patient, 68 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute myocardial infarction, acute respiratory distress syndrome, multi-organ failure. Xigris dosage: unknown. Patient died on 11/01/2005.

Xigris Side Effects Report #6124210-0
Xigris side effect was reported by a Physician from INDIA on Mar 13, 2009. Female patient, 65 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, hypotension, multi-organ failure, sepsis . Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS, DOPAMINE. Patient was hospitalized. Patient died.

Xigris Side Effects Report #6119239-2
Xigris side effect was reported by a Physician from INDIA on Mar 09, 2009. Female patient, 64 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, pneumonia . Xigris dosage: unknown. Patient was hospitalized. Patient died on 03/09/2009.


Xigris Side Effects Report #6120081-7
Xigris side effect was reported by a Physician from INDIA on Mar 09, 2009. Female patient, 64 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, pneumonia . Xigris dosage: unknown. Patient was hospitalized. Patient died on 03/09/2009.

Xigris Side Effects Report #5802579-1
Xigris side effect was reported by a Physician from FRANCE on June 24, 2008. Female patient, 47 years of age, weighting 209.4 lb, was diagnosed with multi-organ failure, sedation, intestinal fistula and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MIDAZOLAM, FENTANYL, NIMBEX, SANDOSTATIN, CIFLOX, VANCOMYCIN, TRIFLUCAN. Patient died on 06/07/2008.

Xigris Side Effects Report #6091446-7
Xigris side effect was reported by a Physician from INDIA on Feb 18, 2009. Male patient, 44 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Xigris dosage: unknown. Patient was hospitalized. Patient died on 02/17/2009.

Xigris Side Effects Report #4928192-6
Xigris side effect was reported by a Physician from GERMANY on Feb 03, 2006. Male patient, 15 years of age, weighting 154.3 lb, was diagnosed with meningococcal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: circulatory collapse, condition aggravated, meningococcal sepsis, multi-organ failure, renal failure, respiratory failure. Xigris dosage: unknown. During the same period patient was treated with CLAFORAN, ARIVEN, NORADRENALINE, DORMICUM ROCHE, SUFENTA, HYDROCORTISONE, OMEPRAZOLE. Patient was hospitalized. Patient died on 01/29/2006.

Xigris Side Effects Report #4746749-2
Xigris side effect was reported by a Health Professional from AUSTRALIA on Aug 01, 2005. Male patient, 57 years of age, weighting 242.5 lb, was diagnosed with intestinal perforation, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac failure, multi-organ failure, renal failure. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5072781-8
Xigris side effect was reported by a Physician from UNITED KINGDOM on July 17, 2006. Female patient, 77 years of age, weighting 99.21 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, liver function test abnormal, multi-organ failure. Xigris dosage: 24 UG INTRAVENOUS ; 12 ML EVERY HOUR INTRAVENOUS ; 12 ML EVERY HOUR SUBCUTANEOUS. During the same period patient was treated with CHLORIDE, DIGOXIN, LEVOTHYROXINE, WARFARIN, NICORANDIL, CARVEDILOL. Patient recovered.

Xigris Side Effects Report #4686773-1
Xigris side effect was reported by a Physician from on May 19, 2005. Female patient, 76 years of age, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardio-respiratory arrest, haemoglobin decreased, haemorrhage, international normalised ratio decreased, multi-organ failure, platelet count decreased. Xigris dosage: unknown. Patient died on 06/18/2004.

Xigris Side Effects Report #5759609-5
Xigris side effect was reported by a Physician from MEXICO on May 28, 2008. Female patient, 29 years of age, weighting 330.7 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: bronchial haemorrhage, epistaxis, gastrointestinal haemorrhage, genital haemorrhage, multi-organ failure, urinary bladder haemorrhage. Xigris dosage: unknown. Patient died on 05/27/2008.

Xigris Side Effects Report #5816052-8
Xigris side effect was reported by a Physician from MEXICO on July 09, 2008. Female patient, 29 years of age, weighting 330.7 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: bronchial haemorrhage, epistaxis, gastrointestinal haemorrhage, genital haemorrhage, multi-organ failure, urinary bladder haemorrhage. Xigris dosage: unknown. Patient died on 05/27/2008.

Xigris Side Effects Report #4791680-X
Xigris side effect was reported by a Physician from CANADA on Sept 19, 2005. Female patient, 74 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, septic shock. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5208816-9
Xigris side effect was reported by a Physician from UNITED STATES on Jan 09, 2007. Male patient, 63 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: lung neoplasm malignant, multi-organ failure, pharyngeal haemorrhage. Xigris dosage: unknown. During the same period patient was treated with ASPIRIN, PLAVIX. Patient died on 11/01/2006.

Xigris Side Effects Report #5374458-8
Xigris side effect was reported by a Physician from UNITED STATES on June 21, 2007. Male patient, 60 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure. Xigris dosage: unknown. Patient died on 06/01/2007.

Xigris Side Effects Report #4759179-4
Xigris side effect was reported by a Physician from SAUDI ARABIA on Aug 11, 2005. Male patient, 52 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, multi-organ failure, thrombocytopenia. Xigris dosage: 2.16 MG HOUR. During the same period patient was treated with CEFEPIME, CIPROFLOXACIN, NEUPOGEN, HYDROCORTISONE, FLUCONAZOLE, VANCOMYCIN. Patient died on 06/15/2005.

Xigris Side Effects Report #4781680-8
Xigris side effect was reported by a Consumer or non-health professional from ICELAND on Sept 08, 2005. Female patient, 50 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: blood pressure increased, disseminated intravascular coagulation, multi-organ failure, mydriasis, nervous system disorder, pupillary reflex impaired. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5140433-1
Xigris side effect was reported by a Consumer or non-health professional from FRANCE on Oct 04, 2006. Female patient, 40 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: bradycardia, haemodynamic instability, liver disorder, multi-organ failure, nervous system disorder, renal disorder, respiratory disorder, rhabdomyolysis. Xigris dosage: unknown. During the same period patient was treated with CYMEVAN, WELLVONE, PROGRAF, BACTRIM, IMURAN, CEFIXIME CHEWABLE, CORTICOSTEROIDS. Patient was hospitalized. Patient died on 07/24/2006.

Xigris Side Effects Report #5164685-7
Xigris side effect was reported by a Physician from FRANCE on Oct 04, 2006. Female patient, 40 years of age, was diagnosed with pneumocystis jiroveci pneumonia and was treated with Xigris. After drug was administered, patient experienced the following side effects: bradycardia, multi-organ failure, rhabdomyolysis, ventricular tachycardia. Xigris dosage: unknown. During the same period patient was treated with CYMEVAN, PROGRAF, BACTRIM, IMUREL, OROKEN, CORTICOSTEROIDS. Patient was hospitalized. Patient died on 07/24/2006.

Xigris Side Effects Report #5683087-8
Xigris side effect was reported by a Physician from CANADA on Mar 17, 2008. Female patient was treated with Xigris. After drug was administered, patient experienced the following side effects: multi-organ failure, septic shock. Xigris dosage: unknown. Patient died on 03/01/2008.