Xigris and international normalised ratio increased Patient Reports February 12, 2012

Xigris Side Effects Report #4872684-5
Xigris side effect was reported by a Physician from ITALY on Dec 21, 2005. Male patient, 78 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haematoma, condition aggravated, convulsion, haemorrhage intracranial, infusion related reaction, international normalised ratio increased, prothrombin time prolonged, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, NOREPINEPHRINE BITARTRATE, DOBUTAMINE. Patient was hospitalized. Patient died on 09/05/2005.

Xigris Side Effects Report #4545957-3
Xigris side effect was reported by a Physician from on Dec 10, 2004. Female patient, 66 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4579462-5
Xigris side effect was reported by a Consumer or non-health professional from on Jan 19, 2005. Male patient, 65 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, depressed level of consciousness, hydrocephalus , international normalised ratio increased, intracranial pressure increased, mydriasis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient died on 12/25/2004.

Xigris Side Effects Report #4630493-6
Xigris side effect was reported by a Physician from on Mar 18, 2005. Male patient, 54 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. Patient recovered.


Xigris Side Effects Report #4719185-2
Xigris side effect was reported by a Health Professional from UNITED KINGDOM on June 30, 2005. Female patient, 25 years of age, weighting 88.18 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time shortened, haemorrhage, haemorrhage subcutaneous, haemothorax, international normalised ratio increased, pleural effusion, pneumothorax, purpura fulminans. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4741463-1
Xigris side effect was reported by a Physician from UNITED KINGDOM on July 26, 2005. Female patient, 25 years of age, weighting 88.18 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, haemorrhage subcutaneous, haemothorax, international normalised ratio abnormal, international normalised ratio increased, pneumothorax, post procedural complication, purpura fulminans. Xigris dosage: unknown. During the same period patient was treated with CEFUROXIME, METRONIDAZOLE, RIFAMPICIN, CIPROFLOXACIN, STREPTOMYCIN, ISONIAZID, ALBUTEROL SULPHATE HFA, RANITIDINE. Patient died on 07/01/2005.

Xigris Side Effects Report #5094430-5
Xigris side effect was reported by a Pharmacist from CANADA on Aug 08, 2006. Female patient was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5756984-2
Xigris side effect was reported by a Physician from CANADA on May 23, 2008. Female patient, weighting 224.9 lb, was diagnosed with septic shock, blood pressure decreased, endotracheal intubation and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac fibrillation, disseminated intravascular coagulation, haemoglobin decreased, international normalised ratio increased, neutropenia, pneumonia staphylococcal, renal failure, septic shock, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSIN, PROPOFOL, FENTANYL, HEPARIN. Patient died on 04/16/2008.

Xigris Side Effects Report #5002354-4
Xigris side effect was reported by a Pharmacist from CANADA on Apr 27, 2006. Female patient was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. Patient recovered.


Xigris Side Effects Report #5247723-2
Xigris side effect was reported by a Physician from UNITED STATES on Feb 19, 2007. Female patient, 82 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, hepatic enzyme abnormal, international normalised ratio increased, platelet count decreased, sepsis . Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient died on 12/12/2006.

Xigris Side Effects Report #5179523-6
Xigris side effect was reported by a Physician from UNITED STATES on Dec 12, 2006. Female patient, 82 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: hepatic enzyme abnormal, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient recovered.

Xigris Side Effects Report #4870183-8
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 14, 2005. Female patient, 81 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemoglobin decreased, international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with CEFOTETAN, HEPARIN, NOREPINEPHRINE BITARTRATE, ALBUMIN. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4600095-6
Xigris side effect was reported by a Physician from on Feb 11, 2005. Male patient, 80 years of age, weighting 165.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, catheter site haemorrhage, convulsion, haemorrhage intracranial, incision site haemorrhage, international normalised ratio increased, platelet count decreased, prothrombin time prolonged, upper gastrointestinal haemorrhage. Xigris dosage: unknown. During the same period patient was treated with PIPERACILLIN W, MEROPENEM, METROGYL, PANTOPRAZOLE, LASIX, MANNITOL, TAXIM. Patient died on 12/30/2004.

Xigris Side Effects Report #4734250-1
Xigris side effect was reported by a Pharmacist from UNITED STATES on July 07, 2005. Male patient, 78 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, c-reactive protein increased, immune system disorder, international normalised ratio increased, pyrexia, red blood cell sedimentation rate increased. Xigris dosage: unknown. During the same period patient was treated with LOTREL, ASPIRIN, LASIX, ALLOPURINOL, PREVACID, LEVOPHED, ATIVAN. Patient recovered.


Xigris Side Effects Report #4957338-9
Xigris side effect was reported by a Pharmacist from UNITED STATES on Mar 15, 2006. Female patient, 76 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiac arrest , cardio-respiratory arrest, hypotension, international normalised ratio increased, laboratory test interference, pneumothorax, respiratory failure. Xigris dosage: unknown. Patient died on 03/08/2006.

Xigris Side Effects Report #5446157-5
Xigris side effect was reported by a Physician from UNITED STATES on Aug 29, 2007. Male patient, 73 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood bilirubin increased, hepatic failure, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with AMINO ACIDS NOS, CIPRO, DIGOXIN. Patient recovered.

Xigris Side Effects Report #5968410-9
Xigris side effect was reported by a Physician from UNITED STATES on Nov 17, 2008. Female patient, 72 years of age, was diagnosed with sepsis , mechanical ventilation and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with OXYGEN. Patient recovered.

Xigris Side Effects Report #4824526-1
Xigris side effect was reported by a Health Professional from UNITED KINGDOM on Oct 22, 2005. Male patient, 72 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE, DOBUTAMINE, HEPARIN. Patient recovered.

Xigris Side Effects Report #4806285-1
Xigris side effect was reported by a Pharmacist from UNITED STATES on Sept 30, 2005. Female patient, 71 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. Patient recovered.


Xigris Side Effects Report #5200040-9
Xigris side effect was reported by a Physician from UNITED STATES on Dec 27, 2006. Female patient, 70 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MORPHINE, PEPCID, LIDOCAINE, ATIVAN, ROCEPHIN, INSULIN, ZYVOX, LEVOPHED. Patient died on 12/28/2006.

Xigris Side Effects Report #4791673-2
Xigris side effect was reported by a Physician from UNITED KINGDOM on Sept 16, 2005. Female patient, 70 years of age, weighting 121.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood culture positive, international normalised ratio increased, platelet count decreased, pseudomonas infection, sputum culture positive. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE, NORADRENALINE, TAZOCIN, METRONIDAZOLE, CEFTAZIDIME. Patient died on 09/08/2005.

Xigris Side Effects Report #5071853-1
Xigris side effect was reported by a Pharmacist from UNITED STATES on July 18, 2006. Female patient, 69 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE BITARTRATE, PROTONIX, ZOSYN, MORPHINE, ATIVAN, PRIMAXIN, INSULIN. Patient recovered.

Xigris Side Effects Report #5299597-1
Xigris side effect was reported by a Physician from UNITED STATES on Apr 06, 2007. Male patient, 65 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with MILRINONE, LEVOPHED. Patient recovered.

Xigris Side Effects Report #4648368-5
Xigris side effect was reported by a Physician from on Apr 13, 2005. Male patient, 65 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood fibrinogen increased, cerebral haemorrhage, depressed level of consciousness, encephalopathy, hydrocephalus , international normalised ratio increased, intracranial pressure increased, mydriasis. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient died on 12/25/2004.


Xigris Side Effects Report #4764484-1
Xigris side effect was reported by a Physician from UNITED STATES on Aug 22, 2005. Female patient, 64 years of age, weighting 138.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood ph decreased, haematocrit decreased, haemoglobin decreased, international normalised ratio increased, oxygen saturation decreased, pco2 decreased, platelet count decreased, septic shock. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, VALSOPRESSINECTION, ASPIRIN, SEVELAMER, CILASTATIN W, ALLOPURINOL, LEVOFLOXACIN, HYDROCHLROTISONE. Patient died on 08/17/2005.

Xigris Side Effects Report #5427432-7
Xigris side effect was reported by a Physician from UNITED STATES on Aug 22, 2007. Female patient, 62 years of age, weighting 451.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with FLUCONAZOLE, MERREM, VANCOMYCIN, PHENYLEPHRINE, NOREPINEPHRINE, REGLAN, PROCRIT. Patient recovered.

Xigris Side Effects Report #5202321-1
Xigris side effect was reported by a Physician from UNITED KINGDOM on Dec 29, 2006. Female patient, 61 years of age, weighting 176.4 lb, was diagnosed with sepsis , analgesic effect, sedation and was treated with Xigris. After drug was administered, patient experienced the following side effects: accidental overdose, activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: 2.304 MG/KG, UNK. During the same period patient was treated with CIPROFLOXACIN, PENICILLIN G, NORADRENALINE, FENTANYL TRANSDERMAL SYSTEM, MIDAZOLAM HYDROCHLORIDE. Patient recovered.

Xigris Side Effects Report #5144352-6
Xigris side effect was reported by a Physician from UNITED STATES on Oct 18, 2006. Female patient, 61 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4935902-0
Xigris side effect was reported by a Pharmacist from UNITED STATES on Feb 13, 2006. Female patient, 61 years of age, weighting 330.0 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: disease recurrence, haemorrhage, international normalised ratio increased, platelet count decreased, sepsis . Xigris dosage: unknown. During the same period patient was treated with PROTONIX, HYDROCORTISONE, DIFLUCAN, LEVAQUIN, ZYVOX, BACTRIM, PRIMAXIN. Patient died.


Xigris Side Effects Report #4949358-5
Xigris side effect was reported by a Pharmacist from UNITED STATES on Feb 23, 2006. Female patient, 61 years of age, weighting 330.0 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, international normalised ratio increased, multi-organ failure, platelet count decreased, sepsis . Xigris dosage: unknown. During the same period patient was treated with PROTONIX, HYDROCORTISONE, DIFLUCAN, LEVAQUINN, ZYVOX, BACTRIM, PRIMAXIN. Patient died.

Xigris Side Effects Report #5031391-9
Xigris side effect was reported by a Pharmacist from UNITED KINGDOM on May 31, 2006. Female patient, 61 years of age, weighting 143.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: accidental overdose, activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4746254-3
Xigris side effect was reported by a Health Professional from UNITED STATES on Aug 03, 2005. Female patient, 60 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5278060-8
Xigris side effect was reported by a Physician from UNITED STATES on Mar 20, 2007. Male patient, 58 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, multi-organ failure. Xigris dosage: unknown. Patient died on 03/08/2007.

Xigris Side Effects Report #4883849-0
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 29, 2005. Female patient, 58 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSINECTION, DOPAMINE, HEPARN. Patient recovered.


Xigris Side Effects Report #4898950-5
Xigris side effect was reported by a Pharmacist from UNITED STATES on Jan 17, 2006. Female patient, 58 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, hepatic failure, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSINECTION, DOPAMINE, HEPARIN. Patient died on 12/30/2005.

Xigris Side Effects Report #5200045-8
Xigris side effect was reported by a Physician from UNITED STATES on Dec 28, 2006. Male patient, 56 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased, prothrombin time prolonged. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4752537-3
Xigris side effect was reported by a Pharmacist from CANADA on Aug 08, 2005. Female patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood pressure decreased, disseminated intravascular coagulation, haemorrhage, international normalised ratio increased, renal failure chronic, thrombocytopenia. Xigris dosage: unknown. Patient died on 07/18/2005.

Xigris Side Effects Report #4758587-5
Xigris side effect was reported by a Pharmacist from CANADA on Aug 08, 2005. Female patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, disseminated intravascular coagulation, haemorrhage, international normalised ratio increased, renal failure chronic, thrombocytopenia. Xigris dosage: unknown. Patient died on 07/18/2005.

Xigris Side Effects Report #5735865-4
Xigris side effect was reported by a Physician from UNITED STATES on May 06, 2008. Female patient, 54 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haematuria, haemorrhage, incision site haemorrhage, international normalised ratio increased, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with LOVENOX. Patient died on 03/18/2008.


Xigris Side Effects Report #6010527-7
Xigris side effect was reported by a Physician from UNITED KINGDOM on Dec 04, 2008. Male patient, 54 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with ANTIBIOTICS, ANABOLIC STEROIDS, ALBUTEROL. Patient recovered.

Xigris Side Effects Report #4827612-5
Xigris side effect was reported by a Pharmacist from UNITED STATES on Oct 31, 2005. Male patient, 54 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4871521-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 16, 2005. Male patient, 54 years of age, weighting 166.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiac arrest , haematocrit decreased, haemodialysis, international normalised ratio increased, thrombocytopenia, ventricular fibrillation, wound haemorrhage. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4875933-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 25, 2005. Male patient, 54 years of age, weighting 166.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , international normalised ratio increased, thrombocytopenia, ventricular fibrillation, wound haemorrhage. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4883823-4
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 28, 2005. Male patient, 54 years of age, weighting 176.4 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , cerebral haemorrhage, convulsion, international normalised ratio increased, pyothorax, septic embolus. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, DILANTIN, CEFTRIAXONE, DIFLUCAN, NAFCILLIN, FENTANYL CITRATE, PEPCID, ATROVENT. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4890987-5
Xigris side effect was reported by a Pharmacist from UNITED STATES on Jan 12, 2006. Male patient, 54 years of age, weighting 166.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , haematocrit decreased, haemodialysis, international normalised ratio increased, thrombocytopenia, ventricular fibrillation, wound haemorrhage. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4718879-2
Xigris side effect was reported by a Physician from UNITED KINGDOM on June 30, 2005. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count, platelet count decreased, urinary bladder haemorrhage. Xigris dosage: unknown. During the same period patient was treated with TERLIPRESSIN, DOBUTAMINE IN DEXTROSE, NORADRENALINE, CEFTRIAXONE, HYDROCORTISONE, PROPOFOL, ALFENTANIL, TAZOCIN. Patient recovered.

Xigris Side Effects Report #4815032-9
Xigris side effect was reported by a Health Professional from INDIA on Oct 07, 2005. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time, activated partial thromboplastin time prolonged, blood creatinine increased, cerebral haemorrhage, international normalised ratio increased, loss of consciousness, mydriasis, peritoneal dialysis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with SEDATIVE, MUSCLE RELAXANT, ANTIBIOTIC. Patient was hospitalized. Patient died on 09/28/2005.

Xigris Side Effects Report #4822100-4
Xigris side effect was reported by a Consumer or non-health professional from INDIA on Oct 14, 2005. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood creatine increased, cerebral haemorrhage, international normalised ratio increased, loss of consciousness, mydriasis, peritoneal dialysis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with SEDATIVE, MUSCLE RELAXANT, ANTIBIOTIC. Patient was hospitalized. Patient died on 09/28/2005.

Xigris Side Effects Report #5206082-1
Xigris side effect was reported by a Physician from UNITED STATES on Jan 02, 2007. Female patient, 51 years of age, was diagnosed with sepsis , infection  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with CIPROFLOXACIN, LEVOFLOXACIN, IMIPENEM, VANCOMYCIN HYDROCHLORIDE, CLINDAMYCIN, DIFLUCAN, FLAGYL. Patient recovered.


Xigris Side Effects Report #5017020-9
Xigris side effect was reported by a Physician from UNITED STATES on May 16, 2006. Male patient, 51 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with HEPARIN. Patient recovered.

Xigris Side Effects Report #4871401-2
Xigris side effect was reported by a Physician from UNITED STATES on Dec 14, 2005. Female patient, 50 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. Patient died on 12/13/2005.

Xigris Side Effects Report #4872724-3
Xigris side effect was reported by a Physician from UNITED STATES on Dec 21, 2005. Female patient, 50 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4686712-3
Xigris side effect was reported by a Consumer or non-health professional from on May 20, 2005. Male patient, 49 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, condition aggravated, haemorrhage intracranial, international normalised ratio increased, platelet count decreased, vessel puncture site haemorrhage. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN. Patient was hospitalized. Patient died on 03/29/2005.

Xigris Side Effects Report #6112621-9
Xigris side effect was reported by a Physician from UNITED STATES on Mar 03, 2009. Male patient, 43 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5657504-3
Xigris side effect was reported by a Physician from UNITED STATES on Feb 27, 2008. Female patient, 42 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood glucose increased, diabetic ketoacidosis, international normalised ratio increased, liver function test abnormal, sepsis . Xigris dosage: unknown. During the same period patient was treated with CYMBALTA, ANTIBIOTICS, NEOSYNEPHRINE, LEVOPHED. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5671149-0
Xigris side effect was reported by a Physician from UNITED STATES on Mar 05, 2008. Female patient, 42 years of age, was diagnosed with sepsis , depression  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, diabetes mellitus, diabetic ketoacidosis, international normalised ratio increased, liver function test abnormal, sepsis . Xigris dosage: unknown. During the same period patient was treated with CYMBALTA. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4561534-2
Xigris side effect was reported by a Pharmacist from on Jan 05, 2005. Female patient, 38 years of age, weighting 121.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, international normalised ratio increased, mental status changes, platelet count decreased, prothrombin time prolonged, subdural haematoma. Xigris dosage: unknown. During the same period patient was treated with IMMUNOSUPPRESSANTS. Patient died on 11/17/2004.

Xigris Side Effects Report #4630497-3
Xigris side effect was reported by a Pharmacist from on Mar 19, 2005. Female patient, 37 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: 16.8 ML/HR. Patient recovered.

Xigris Side Effects Report #4686726-3
Xigris side effect was reported by a Physician from on May 20, 2005. Female patient, 36 years of age, weighting 132.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, haematuria, international normalised ratio increased, platelet count decreased. Xigris dosage: 34.3 MG/1 DAY. During the same period patient was treated with ANTITHROMBIN III. Patient recovered.


Xigris Side Effects Report #4949360-3
Xigris side effect was reported by a Physician from UNITED STATES on Feb 24, 2006. Female patient, 33 years of age, weighting 123.5 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, condition aggravated, fibrin d dimer increased, fibrin degradation products increased, haemoglobin decreased, international normalised ratio increased, prothrombin time prolonged. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4618701-9
Xigris side effect was reported by a Pharmacist from on Mar 07, 2005. Female patient, 32 years of age, weighting 169.8 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4746255-5
Xigris side effect was reported by a Pharmacist from UNITED STATES on Aug 02, 2005. Female patient, 23 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with PRESSORS. Patient recovered.

Xigris Side Effects Report #4764308-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Aug 23, 2005. Male patient, 23 years of age, weighting 176.4 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, disseminated intravascular coagulation, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with IMIPENEM, VANCOMYCIN, FLAGYL, PREVACID. Patient recovered.

Xigris Side Effects Report #5097094-X
Xigris side effect was reported by a Physician from UNITED STATES on Aug 17, 2006. Male patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with COUMADIN. Patient recovered.

Xigris Side Effects Report #5161955-3
Xigris side effect was reported by a Physician from UNITED STATES on Nov 22, 2006. Male patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5800209-6
Xigris side effect was reported by a Physician from UNITED STATES on June 20, 2008. Female patient, weighting 308.6 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haematuria, haemorrhage, international normalised ratio increased, prothrombin time prolonged, sepsis . Xigris dosage: unknown. During the same period patient was treated with LOVENOX. Patient died on 03/18/2008.

Xigris Side Effects Report #4845473-5
Xigris side effect was reported by a Pharmacist from UNITED STATES on Nov 09, 2005. Male patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage, international normalised ratio increased. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4955113-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Mar 09, 2006. Female patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, laboratory test interference. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4995384-X
Xigris side effect was reported by a Pharmacist from UNITED STATES on Apr 18, 2006. Female patient, weighting 200.6 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. Patient recovered.


Xigris Side Effects Report #4936378-X
Xigris side effect was reported by a Physician from UNITED STATES on Feb 16, 2006. Female patient was diagnosed with pneumonia  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4719083-4
Xigris side effect was reported by a Physician from POLAND on July 01, 2005. Male patient, 64 years of age, weighting 132.3 lb, was diagnosed with multi-organ failure, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiopulmonary failure, coagulopathy, gastrointestinal haemorrhage, international normalised ratio increased, respiratory tract haemorrhage. Xigris dosage: unknown. During the same period patient was treated with MERONMEN, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, MIDAZOLAM, GAMMAGARD. Patient died on 10/31/2004.

Xigris Side Effects Report #4630747-3
Xigris side effect was reported by a Pharmacist from on Mar 17, 2005. Female patient, 57 years of age, weighting 392.4 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemoglobin decreased, haemorrhage urinary tract, international normalised ratio increased, mouth haemorrhage, platelet count decreased, prothrombin time prolonged, septic shock. Xigris dosage: unknown. During the same period patient was treated with GENTAMICIN, ZOSYN, HEPARIN, AVELOX, TYLENOL, PHENYLEPHRINE, DOPAMINE, NOREPINEPHRINE. Patient died on 10/25/2004.

Xigris Side Effects Report #4752412-4
Xigris side effect was reported by a Health Professional from UNITED KINGDOM on Aug 10, 2005. Female patient, 65 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: blood pressure systolic increased, international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4765617-3
Xigris side effect was reported by a Health Professional from UNITED KINGDOM on Aug 19, 2005. Female patient, 61 years of age, weighting 176.4 lb, was treated with Xigris. After drug was administered, patient experienced the following side effects: hypertension, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with CEFUROXIME, ERYTHROMYCIN, RANITIDINE, METRONIDAZOLE, HYDROCORTISONE, METOCLOPRAMIDE, FUROSEMIDE, INSULIN. Patient recovered.

Xigris Side Effects Report #5263915-0
Xigris side effect was reported by a Physician from UNITED STATES on Mar 07, 2007. Male patient, 58 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4648547-7
Xigris side effect was reported by a Pharmacist from on Apr 12, 2005. Female patient, 54 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, laboratory test abnormal. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS, HYDROCORTISONE, RANITIDINE, ADRENALINE, NORADRENALINE. Patient recovered.

Xigris Side Effects Report #6033049-6
Xigris side effect was reported by a Physician from CANADA on Jan 06, 2009. Female patient, 53 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time, haemorrhage subcutaneous, international normalised ratio increased. Xigris dosage: unknown. Patient died on 01/02/2009.

Xigris Side Effects Report #4824555-8
Xigris side effect was reported by a Physician from UNITED KINGDOM on Oct 26, 2005. Female patient was treated with Xigris. After drug was administered, patient experienced the following side effects: international normalised ratio increased, thrombocytopenia. Xigris dosage: 24 MG/KG/HR. Patient recovered.