Xigris and gastrointestinal haemorrhage Patient Reports February 12, 2012

Xigris Side Effects Report #5085009-X
Xigris side effect was reported by a Pharmacist from UNITED STATES on July 30, 2006. Male patient, 73 years of age, was diagnosed with urosepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, post procedural complication. Xigris dosage: 1.8 MG, EVERY HOUR, INTRAVENOUS. Patient died.

Xigris Side Effects Report #5405152-2
Xigris side effect was reported by a Physician from MEXICO on July 19, 2007. Female patient, 48 years of age, was diagnosed with shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal sepsis, epistaxis, gastrointestinal haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MEROPENEM, OMEPRAZOLE, METRONIDAZOLE, AMINOPHYLLINE. Patient died on 06/17/2007.

Xigris Side Effects Report #5430524-X
Xigris side effect was reported by a Physician from MEXICO on Aug 20, 2007. Female patient, 48 years of age, was diagnosed with shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal sepsis, epistaxis, gastrointestinal haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MEROPENEM, OMEPRAZOLE, METRONIDAZOLE, AMINOPHYLLINE. Patient died on 06/17/2007.

Xigris Side Effects Report #4625577-2
Xigris side effect was reported by a Physician from on Mar 10, 2005. Male patient, 79 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, haematocrit decreased, ileus paralytic. Xigris dosage: unknown. Patient was hospitalized. Patient died on 03/06/2005.


Xigris Side Effects Report #4630265-2
Xigris side effect was reported by a Physician from on Mar 16, 2005. Male patient, 79 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, haematocrit decreased, ileus paralytic. Xigris dosage: unknown. Patient was hospitalized. Patient died on 03/06/2005.

Xigris Side Effects Report #5961486-4
Xigris side effect was reported by a Physician from UNITED STATES on Nov 10, 2008. Male patient, 77 years of age, was diagnosed with septic shock, thrombosis prophylaxis and was treated with Xigris. After drug was administered, patient experienced the following side effects: bradycardia, gastrointestinal haemorrhage, hypotension, pseudomembranous colitis, sepsis . Xigris dosage: unknown. During the same period patient was treated with HEPARIN, ESOMEPRAZOLE MAGNESIUM, PHYTONADIONE, OXYGEN. Patient died on 10/21/2008.

Xigris Side Effects Report #5048758-5
Xigris side effect was reported by a Consumer or non-health professional from FRANCE on June 15, 2006. Male patient, 76 years of age, weighting 176.4 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, meningorrhagia, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with LASIX, PLAVIX, AMLODIPINE BESYLATE, POTASSIUM CHLORIDE, CEFTAZIDIME PENTAHYDRATE, CIFLOX. Patient died on 04/18/2006.

Xigris Side Effects Report #5579334-3
Xigris side effect was reported by a Physician from ITALY on Dec 19, 2007. Male patient, 75 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: unknown. Patient died on 01/08/2004.

Xigris Side Effects Report #6089371-0
Xigris side effect was reported by a Physician from SWITZERLAND on Feb 13, 2009. Female patient, 67 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, organ failure. Xigris dosage: unknown. Patient recovered.


Xigris Side Effects Report #5966098-4
Xigris side effect was reported by a Physician from ITALY on Nov 12, 2008. Male patient, 66 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: catheter site haemorrhage, gastrointestinal haemorrhage, post procedural haemorrhage, renal failure, respiratory failure. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, ANTIBIOTICS, IMMUNOSUPPRESSIVE AGENTS, CORTICOSTEROID NOS. Patient recovered.

Xigris Side Effects Report #4620191-7
Xigris side effect was reported by a Pharmacist from on Mar 21, 2005. Male patient, 61 years of age, weighting 174.2 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: 9.5 ML HOUR INTRAVENOU. During the same period patient was treated with AMIODARONE, BACITRACIN, DIGOXIN, ATROVENT, XOPENEX, TERBINAFINE, PEPCID, HYDROCORTIS. Patient recovered.

Xigris Side Effects Report #5284633-9
Xigris side effect was reported by a Physician from on Mar 26, 2007. Female patient, 54 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, thrombocytopenia. Xigris dosage: 40 MG, OTHER. During the same period patient was treated with NORADRENALINE, DOBUTAMINE, FUROSEMIDE, NEXIUM, LINEZOLID, DEFLAMON, DALACIN C PHOSPHAT, URBASON. Patient recovered.

Xigris Side Effects Report #5646843-8
Xigris side effect was reported by a Physician from ITALY on Feb 20, 2008. Female patient was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: 15.8 ML, EVERY HOUR. During the same period patient was treated with IMIPENEM, CEFEPIME, NOREPINEPHRINE, DIFLUCAN, ZYVOX, LASIX. Patient died on 12/29/2004.

Xigris Side Effects Report #4929323-4
Xigris side effect was reported by a Physician from UNITED STATES on Feb 01, 2006. Male patient, 87 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: acquired haemophilia, activated partial thromboplastin time prolonged, factor viii inhibition, fall , gastrointestinal haemorrhage, haemarthrosis, haematocrit decreased, haematuria, haemoglobin decreased. Xigris dosage: unknown. Patient was hospitalized. Patient died on 03/03/2005.


Xigris Side Effects Report #5391530-7
Xigris side effect was reported by a Physician from AUSTRALIA on July 17, 2007. Male patient, 77 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: unknown. Patient died on 07/01/2007.

Xigris Side Effects Report #5520492-4
Xigris side effect was reported by a Physician from AUSTRALIA on Nov 07, 2007. Male patient, 77 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: aspergillosis, gastrointestinal haemorrhage. Xigris dosage: unknown. Patient was hospitalized. Patient died on 07/01/2007.

Xigris Side Effects Report #4851676-6
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 09, 2005. Female patient, 71 years of age, weighting 138.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: 1500 MCG/HR 10 ML/HR IV DRIP. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4649183-9
Xigris side effect was reported by a Pharmacist from on Apr 12, 2005. Female patient, 68 years of age, weighting 224.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: b-cell lymphoma, gastrointestinal haemorrhage, lobar pneumonia. Xigris dosage: unknown. During the same period patient was treated with PRIMAXIN, METHYLPREDNISOLONE, DOPAMINE, LEVOPHED, ALBUTEROL, IPRATROPIUM BROMIDE. Patient died on 03/13/2005.

Xigris Side Effects Report #5197091-X
Xigris side effect was reported by a Physician from UNITED KINGDOM on Dec 22, 2006. Female patient, 66 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, multi-organ failure, septic shock. Xigris dosage: 9.7 ML, EVERY HOUR. During the same period patient was treated with ALFENTANIL, ATRACURIUM BESYLATE, CEFTRIAXONE, DOPEXAMINE, ENOXAPARIN, FLOLAN, HYDROCORTISONE, METRONIDAZOLE. Patient died on 11/30/2006.


Xigris Side Effects Report #5151743-6
Xigris side effect was reported by a Physician from AUSTRALIA on Oct 19, 2006. Female patient, 61 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, intra-abdominal haemorrhage. Xigris dosage: 24 MG/KG. Patient died on 10/18/2006.

Xigris Side Effects Report #4562911-6
Xigris side effect was reported by a Health Professional from on Dec 30, 2004. Male patient, 61 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, multi-organ failure, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with HIGH DOSE VASOPRESSORS, METRONIDAZOLE. Patient recovered.

Xigris Side Effects Report #4898270-9
Xigris side effect was reported by a Physician from UNITED STATES on Jan 19, 2006. Female patient, 61 years of age, weighting 205.0 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: brain oedema, condition aggravated, gastrointestinal haemorrhage, performance status decreased, septic shock. Xigris dosage: unknown. Patient was hospitalized. Patient died on 11/17/2005.

Xigris Side Effects Report #4949921-1
Xigris side effect was reported by a Physician from UNITED STATES on Mar 02, 2006. Female patient, 61 years of age, weighting 205.0 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: brain oedema, disease progression, gastrointestinal haemorrhage, international normalised ratio abnormal, multi-organ failure, septic shock. Xigris dosage: unknown. Patient was hospitalized. Patient died on 11/17/2005.

Xigris Side Effects Report #5104068-9
Xigris side effect was reported by a Physician from POLAND on Aug 21, 2006. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, haemorrhage intracranial, neurological symptom, peritoneal abscess, peritoneal haemorrhage, shock haemorrhagic, upper gastrointestinal haemorrhage. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient was hospitalized. Patient died.


Xigris Side Effects Report #4680442-X
Xigris side effect was reported by a Physician from on May 13, 2005. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, haemorrhage intracranial, neurological symptom, peritoneal haemorrhage. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient was hospitalized. Patient died.

Xigris Side Effects Report #6094325-4
Xigris side effect was reported by a Physician from UNITED STATES on Feb 23, 2009. Male patient, 50 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: unknown. Patient died on 02/01/2009.

Xigris Side Effects Report #4871397-3
Xigris side effect was reported by a Physician from UNITED STATES on Dec 09, 2005. Female patient, 50 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4703749-6
Xigris side effect was reported by a Physician from on June 15, 2005. Male patient, 40 years of age, weighting 180.8 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: candidiasis, catheter site haemorrhage, condition aggravated, disseminated intravascular coagulation, fungaemia, gastritis erosive, gastrointestinal haemorrhage, sepsis . Xigris dosage: unknown. During the same period patient was treated with PRIMAXIN, STEROIDS, HEPARIN, INSULIN, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, VASOPRESSINECTION, NEOSYNEPHRINE. Patient died on 03/01/2005.

Xigris Side Effects Report #5864407-8
Xigris side effect was reported by a Physician from UNITED STATES on Aug 18, 2008. Male patient, 30 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, gastrointestinal haemorrhage. Xigris dosage: unknown. Patient recovered.


Xigris Side Effects Report #4595423-4
Xigris side effect was reported by a Health Professional from on Feb 04, 2005. Female patient, 30 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, multi-organ failure. Xigris dosage: unknown. Patient died on 01/18/2005.

Xigris Side Effects Report #5179486-3
Xigris side effect was reported by a Physician from CANADA on Dec 11, 2006. Male patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5735867-8
Xigris side effect was reported by a Consumer or non-health professional from UNITED STATES on May 05, 2008. Male patient, weighting 207.2 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastric ulcer, gastrointestinal haemorrhage, thrombocytopenia. Xigris dosage: 11.4 ML/HR, UNK. Patient recovered.

Xigris Side Effects Report #5140379-9
Xigris side effect was reported by a Physician from INDIA on Oct 09, 2006. Male patient, 52 years of age, weighting 154.3 lb, was diagnosed with pneumonia  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood bilirubin increased, blood creatinine increased, blood pressure systolic decreased, blood urea increased, catheter site haemorrhage, dengue fever, endotracheal intubation complication, gastrointestinal haemorrhage, haemoglobin decreased. Xigris dosage: unknown. Patient was hospitalized. Patient died on 10/06/2006.

Xigris Side Effects Report #4831012-1
Xigris side effect was reported by a Pharmacist from UNITED STATES on Nov 15, 2005. Male patient, 54 years of age, weighting 113.0 lb, was diagnosed with necrotising fasciitis and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, haematemesis, occult blood positive, wound secretion. Xigris dosage: unknown. During the same period patient was treated with FRAGMIN, LEVAQUIN, CLINDAMYCIN, VANCOMYCIN, PROTONIX. Patient recovered.


Xigris Side Effects Report #4719083-4
Xigris side effect was reported by a Physician from POLAND on July 01, 2005. Male patient, 64 years of age, weighting 132.3 lb, was diagnosed with multi-organ failure, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiopulmonary failure, coagulopathy, gastrointestinal haemorrhage, international normalised ratio increased, respiratory tract haemorrhage. Xigris dosage: unknown. During the same period patient was treated with MERONMEN, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, MIDAZOLAM, GAMMAGARD. Patient died on 10/31/2004.

Xigris Side Effects Report #5051889-7
Xigris side effect was reported by a Health Professional from UNITED STATES on June 19, 2006. Male patient, 65 years of age, was diagnosed with disseminated intravascular coagulation and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, disseminated intravascular coagulation, gastrointestinal haemorrhage, platelet count decreased, sepsis . Xigris dosage: unknown. Patient died on 06/01/2006.

Xigris Side Effects Report #5774874-6
Xigris side effect was reported by a Physician from MEXICO on June 05, 2008. Female patient, 33 years of age, was diagnosed with blood disorder and was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage, pseudomonas infection, thrombocytopenia. Xigris dosage: 20 MG, UNK. During the same period patient was treated with ANTIBIOTICS. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5759609-5
Xigris side effect was reported by a Physician from MEXICO on May 28, 2008. Female patient, 29 years of age, weighting 330.7 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: bronchial haemorrhage, epistaxis, gastrointestinal haemorrhage, genital haemorrhage, multi-organ failure, urinary bladder haemorrhage. Xigris dosage: unknown. Patient died on 05/27/2008.

Xigris Side Effects Report #5816052-8
Xigris side effect was reported by a Physician from MEXICO on July 09, 2008. Female patient, 29 years of age, weighting 330.7 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: bronchial haemorrhage, epistaxis, gastrointestinal haemorrhage, genital haemorrhage, multi-organ failure, urinary bladder haemorrhage. Xigris dosage: unknown. Patient died on 05/27/2008.


Xigris Side Effects Report #4762175-4
Xigris side effect was reported by a Pharmacist from UNITED STATES on Sept 06, 2005. Male patient, 74 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5797937-8
Xigris side effect was reported by a Physician from UNITED STATES on June 18, 2008. Female patient, 70 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: gastric ulcer, gastrointestinal haemorrhage. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4964481-7
Xigris side effect was reported by a Physician from CANADA on Mar 16, 2006. Female patient, 53 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: gastrointestinal haemorrhage. Xigris dosage: unknown. During the same period patient was treated with PREDNISONE, ASPIRIN, URSODIOL, AZATHROPRINE, SYNTHROID, RAMIPRIL, GLYBURIDE, HEPARIN. Patient died.