Xigris and epistaxis Patient Reports February 12, 2012

Xigris Side Effects Report #5405152-2
Xigris side effect was reported by a Physician from MEXICO on July 19, 2007. Female patient, 48 years of age, was diagnosed with shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal sepsis, epistaxis, gastrointestinal haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MEROPENEM, OMEPRAZOLE, METRONIDAZOLE, AMINOPHYLLINE. Patient died on 06/17/2007.

Xigris Side Effects Report #5430524-X
Xigris side effect was reported by a Physician from MEXICO on Aug 20, 2007. Female patient, 48 years of age, was diagnosed with shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal sepsis, epistaxis, gastrointestinal haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with MEROPENEM, OMEPRAZOLE, METRONIDAZOLE, AMINOPHYLLINE. Patient died on 06/17/2007.

Xigris Side Effects Report #4549348-0
Xigris side effect was reported by a Physician from on Dec 20, 2004. Female patient, 76 years of age, weighting 154.3 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen increased, disseminated intravascular coagulation, epistaxis, fibrin d dimer increased, haemoglobin decreased, injection site haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with ANTITHROMBIN III, HEPARIN, MIDAZOLAM, CISATRACURIUM, FENTANYL, NORADRENALINE, DOPAMINE, DOBUTAMINE. Patient died on 12/16/2004.

Xigris Side Effects Report #5022700-5
Xigris side effect was reported by a Consumer or non-health professional from FRANCE on May 22, 2006. Male patient, 53 years of age, weighting 194.0 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, epistaxis, meningorrhagia, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with ASPEGIC, HYDROCORTISONE, NIMBEX, INSULIN, PERFALGAN, ALPRAZOLAM, LIORESAL, EZETROL. Patient died on 01/30/2006.


Xigris Side Effects Report #5618825-3
Xigris side effect was reported by a Physician from ITALY on Jan 25, 2008. Male patient was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, pancreatitis haemorrhagic, pancreatitis necrotising, shock haemorrhagic. Xigris dosage: unknown. During the same period patient was treated with GENTAMICIN, DOPAMINE, NORADRENALINE, TAZOCIN, NEXIUM, CLEXANE, DEFLAMON. Patient died on 01/11/2008.

Xigris Side Effects Report #4608743-1
Xigris side effect was reported by a Consumer or non-health professional from on Feb 22, 2005. Male patient, 73 years of age, weighting 143.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute myocardial infarction, bacterial sepsis, confusional state, epistaxis, hydronephrosis, mouth haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE, CIPROFLOXACIN, NORADRENALINE. Patient recovered.

Xigris Side Effects Report #6077713-1
Xigris side effect was reported by a Physician from SPAIN on Feb 03, 2009. Male patient, 69 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, pneumonia . Xigris dosage: unknown. During the same period patient was treated with OXYGEN. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4691978-X
Xigris side effect was reported by a Pharmacist from on June 16, 2005. Male patient, 65 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, haemorrhage, hypotension, mouth haemorrhage. Xigris dosage: 63 MG Q 24 HOURS INTRAVENOU. Patient died on 12/02/2004.

Xigris Side Effects Report #5740413-9
Xigris side effect was reported by a Physician from SPAIN on May 06, 2008. Male patient, 56 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, thrombocytopenia, wound haemorrhage. Xigris dosage: 0.024 MG/KG, EVERY HOUR. Patient was hospitalized. Patient recovered.


Xigris Side Effects Report #5961367-6
Xigris side effect was reported by a Physician from SPAIN on Nov 07, 2008. Male patient, 56 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haemorrhage, epistaxis, thrombocytopenia, wound haemorrhage. Xigris dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with HEPARIN. Patient died.

Xigris Side Effects Report #6037332-X
Xigris side effect was reported by a Physician from SPAIN on Jan 07, 2009. Male patient, 56 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haemorrhage, epistaxis, thrombocytopenia, wound haemorrhage. Xigris dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with HEPARIN. Patient died on 06/16/2008.

Xigris Side Effects Report #5150888-4
Xigris side effect was reported by a Physician from INDIA on Nov 03, 2006. Male patient, 51 years of age, weighting 198.4 lb, was diagnosed with sepsis , infection  and was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, haemorrhage, hypotension, lung disorder. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient died on 11/02/2006.

Xigris Side Effects Report #4625668-6
Xigris side effect was reported by a Physician from on Mar 11, 2005. Male patient, 46 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, medical device complication, pulmonary haemorrhage, pulmonary thrombosis, respiratory tract haemorrhage, thrombocytopenia. Xigris dosage: unknown. Patient died on 03/13/2005.

Xigris Side Effects Report #4686726-3
Xigris side effect was reported by a Physician from on May 20, 2005. Female patient, 36 years of age, weighting 132.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, haematuria, international normalised ratio increased, platelet count decreased. Xigris dosage: 34.3 MG/1 DAY. During the same period patient was treated with ANTITHROMBIN III. Patient recovered.


Xigris Side Effects Report #4698750-5
Xigris side effect was reported by a Physician from on June 08, 2005. Female patient, 36 years of age, weighting 132.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, haematuria. Xigris dosage: 34.3 MG/1 DAY. During the same period patient was treated with ANTITHROMBIN III. Patient recovered.

Xigris Side Effects Report #5852877-0
Xigris side effect was reported by a Consumer or non-health professional from BRAZIL on Aug 12, 2008. Female patient, 15 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, mouth haemorrhage. Xigris dosage: unknown. During the same period patient was treated with FLAGYL, VANCOMICINA, INSULIN. Patient was hospitalized. Patient died on 08/08/2008.

Xigris Side Effects Report #4589168-4
Xigris side effect was reported by a Pharmacist from on Feb 15, 2005. Male patient, weighting 138.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, mouth haemorrhage. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4687644-7
Xigris side effect was reported by a Pharmacist from on June 08, 2005. Male patient, 36 years of age, weighting 207.2 lb, was diagnosed with meningitis , sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, mouth haemorrhage, upper gastrointestinal haemorrhage. Xigris dosage: unknown. During the same period patient was treated with DEXAMETHASONE, VANCOMYCIN, CEFOTAXIME, PROPOFOL, ACETAMINOPHEN, INSULIN. Patient recovered.

Xigris Side Effects Report #5759609-5
Xigris side effect was reported by a Physician from MEXICO on May 28, 2008. Female patient, 29 years of age, weighting 330.7 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: bronchial haemorrhage, epistaxis, gastrointestinal haemorrhage, genital haemorrhage, multi-organ failure, urinary bladder haemorrhage. Xigris dosage: unknown. Patient died on 05/27/2008.


Xigris Side Effects Report #5816052-8
Xigris side effect was reported by a Physician from MEXICO on July 09, 2008. Female patient, 29 years of age, weighting 330.7 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: bronchial haemorrhage, epistaxis, gastrointestinal haemorrhage, genital haemorrhage, multi-organ failure, urinary bladder haemorrhage. Xigris dosage: unknown. Patient died on 05/27/2008.

Xigris Side Effects Report #4805491-X
Xigris side effect was reported by a Physician from ARGENTINA on Sept 23, 2005. Female patient, 50 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: bacteraemia, epistaxis. Xigris dosage: unknown. Patient died on 09/05/2005.

Xigris Side Effects Report #4956720-3
Xigris side effect was reported by a Physician from UNITED KINGDOM on Mar 10, 2006. Male patient, 23 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: epistaxis, hepatic enzyme increased, thrombocytopenia. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4692891-4
Xigris side effect was reported by a Consumer or non-health professional from on June 01, 2005. Male patient was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, epistaxis, medical device complication, obstruction, pharyngeal haemorrhage, pneumothorax, respiratory disorder, thrombosis. Xigris dosage: unknown. During the same period patient was treated with NEXIUM, VASOPRESSINECTION, EPINEPHRINE, ZINACEF. Patient died on 03/13/2005.

Xigris Side Effects Report #4883137-2
Xigris side effect was reported by a Health Professional from UNITED STATES on Jan 17, 2006. Female patient, weighting 179.2 lb, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, ear haemorrhage, epistaxis, pharyngeal haemorrhage, platelet count decreased. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.