Xigris and condition aggravated 
Xigris and condition aggravated Patient Reports February 12, 2012
Xigris Side Effects Report #4872684-5
Xigris side effect was reported by a Physician from ITALY on Dec 21, 2005. Male patient, 78 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haematoma, condition aggravated, convulsion, haemorrhage intracranial, infusion related reaction, international normalised ratio increased, prothrombin time prolonged, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, NOREPINEPHRINE BITARTRATE, DOBUTAMINE. Patient was hospitalized. Patient died on 09/05/2005.
Xigris Side Effects Report #4752408-2
Xigris side effect was reported by a Physician from CHILE on Aug 09, 2005. Female patient, 56 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, disease progression, platelet count decreased. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.
Xigris Side Effects Report #4618251-X
Xigris side effect was reported by a Physician from on Mar 03, 2005. Female patient, 51 years of age, weighting 149.9 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal mass, catheter site haemorrhage, cerebral haemorrhage, cholecystitis, coma, condition aggravated, depressed level of consciousness, disseminated intravascular coagulation. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, DOBUTAMINE, LIDOCAINE W, GLIPRESSINA, MERREM, ZITHROMAX, TARGOSID, METRONIDAZOLE. Patient was hospitalized. Patient died on 02/11/2005.
Xigris Side Effects Report #5017139-2
Xigris side effect was reported by a Physician from UNITED STATES on May 04, 2006. Male patient, 77 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, condition aggravated. Xigris dosage: unknown. Patient died on 05/01/2006.Xigris Side Effects Report #4781777-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Sept 13, 2005. Female patient, 72 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, acute respiratory distress syndrome, blood creatine phosphokinase increased, blood urea increased, coagulopathy, condition aggravated, culture urine positive, escherichia infection, faeces discoloured. Xigris dosage: 24 MG/KG/HR. During the same period patient was treated with LOVENOX, DOPAMINE, ASPIRIN, FENTANYL, LORAZEPAM, QUININE, PANTOPRAZOLE. Patient recovered.Xigris Side Effects Report #4733707-7
Xigris side effect was reported by a Physician from FRANCE on July 11, 2005. Female patient, 69 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, thrombocytopenia. Xigris dosage: unknown. Patient recovered.Xigris Side Effects Report #4824148-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Oct 20, 2005. Male patient, 65 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated. Xigris dosage: unknown. Patient recovered.Xigris Side Effects Report #4821516-X
Xigris side effect was reported by a Physician from UNITED STATES on Oct 17, 2005. Male patient, 61 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, dialysis , haemoglobin decreased, operative haemorrhage, renal failure, wound haemorrhage. Xigris dosage: unknown. During the same period patient was treated with CIPROFLOXACIN, CLINDAMYCIN, CEFTRIAXONE, DOPAMINE, MIDAZOLAM, NOREPINEPHRINE, INSULIN, PANTOPRAZOLE. Patient recovered.Xigris Side Effects Report #4898270-9
Xigris side effect was reported by a Physician from UNITED STATES on Jan 19, 2006. Female patient, 61 years of age, weighting 205.0 lb, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: brain oedema, condition aggravated, gastrointestinal haemorrhage, performance status decreased, septic shock. Xigris dosage: unknown. Patient was hospitalized. Patient died on 11/17/2005.Xigris Side Effects Report #4831001-7
Xigris side effect was reported by a Consumer or non-health professional from SPAIN on Oct 24, 2005. Female patient, 59 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, platelet count decreased. Xigris dosage: unknown. Patient recovered.Xigris Side Effects Report #4889211-9
Xigris side effect was reported by a Pharmacist from UNITED STATES on Jan 20, 2006. Male patient, 58 years of age, weighting 185.2 lb, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, pulmonary alveolar haemorrhage. Xigris dosage: unknown. During the same period patient was treated with ZITHROMAX, ROCEPHIN, DOPAMINE, DOBUTAMINE, NOVEPIN, PLATELETS, VANCO. Patient died on 03/01/2005.Xigris Side Effects Report #5531387-4
Xigris side effect was reported by a Physician from GERMANY on Sept 28, 2007. Male patient, 55 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, condition aggravated, multi-organ failure, pneumonia , renal failure, respiratory failure, sepsis , shock. Xigris dosage: unknown. During the same period patient was treated with TAVANIC, TAZOBACTAM, NORADRENALIN. Patient died on 07/14/2007.Xigris Side Effects Report #4758587-5
Xigris side effect was reported by a Pharmacist from CANADA on Aug 08, 2005. Female patient, 55 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, disseminated intravascular coagulation, haemorrhage, international normalised ratio increased, renal failure chronic, thrombocytopenia. Xigris dosage: unknown. Patient died on 07/18/2005.Xigris Side Effects Report #4608739-X
Xigris side effect was reported by a Physician from on Feb 21, 2005. Female patient, 51 years of age, weighting 149.9 lb, was diagnosed with sepsis
, septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, condition aggravated, depressed level of consciousness, haemorrhage intracranial, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, DOBUTAMINE, LIDOCAINE W, GLIPRESSINA, MERREM, ZITHROMAX, TARGOSID. Patient was hospitalized. Patient died on 02/11/2005.Xigris Side Effects Report #4686712-3
Xigris side effect was reported by a Consumer or non-health professional from on May 20, 2005. Male patient, 49 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, condition aggravated, haemorrhage intracranial, international normalised ratio increased, platelet count decreased, vessel puncture site haemorrhage. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN. Patient was hospitalized. Patient died on 03/29/2005.Xigris Side Effects Report #5278041-4
Xigris side effect was reported by a Physician from GERMANY on Mar 20, 2007. Male patient, 45 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, multi-organ failure, sepsis , septic shock. Xigris dosage: 3.9 ML, EVERY HOUR. Patient died on 03/01/2007.Xigris Side Effects Report #4790517-2
Xigris side effect was reported by a Health Professional from UNITED STATES on Sept 15, 2005. Female patient, 44 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, gastrointestinal disorder. Xigris dosage: unknown. Patient recovered.Xigris Side Effects Report #4625579-6
Xigris side effect was reported by a Physician from on Mar 11, 2005. Female patient, 41 years of age, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: atelectasis, condition aggravated, endocarditis , haematoma, haemothorax, left ventricular failure, multi-organ failure, petechiae, phlebothrombosis. Xigris dosage: unknown. Patient died on 03/09/2005.Xigris Side Effects Report #4703749-6
Xigris side effect was reported by a Physician from on June 15, 2005. Male patient, 40 years of age, weighting 180.8 lb, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: candidiasis, catheter site haemorrhage, condition aggravated, disseminated intravascular coagulation, fungaemia, gastritis erosive, gastrointestinal haemorrhage, sepsis . Xigris dosage: unknown. During the same period patient was treated with PRIMAXIN, STEROIDS, HEPARIN, INSULIN, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, VASOPRESSINECTION, NEOSYNEPHRINE. Patient died on 03/01/2005.Xigris Side Effects Report #4949360-3
Xigris side effect was reported by a Physician from UNITED STATES on Feb 24, 2006. Female patient, 33 years of age, weighting 123.5 lb, was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, condition aggravated, fibrin d dimer increased, fibrin degradation products increased, haemoglobin decreased, international normalised ratio increased, prothrombin time prolonged. Xigris dosage: unknown. Patient recovered.Xigris Side Effects Report #5241718-0
Xigris side effect was reported by a Physician from LEBANON on Feb 08, 2007. Female patient was diagnosed with sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, condition aggravated, endocarditis , oliguria. Xigris dosage: unknown. Patient died on 01/01/2006.Xigris Side Effects Report #4549342-X
Xigris side effect was reported by a Physician from on Dec 20, 2004. Male patient, 69 years of age, weighting 165.3 lb, was diagnosed with multi-organ failure, sepsis
and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood fibrinogen increased, coagulation test abnormal, condition aggravated, haematocrit decreased, haematuria, haemoglobin decreased, infusion related reaction, leukocytosis. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, LINEZOLID, MEROPENEM, CIPROFLOXACIN, VORICONAZOLE, FUROSEMIDE, MANNITOL. Patient recovered.Xigris Side Effects Report #4928192-6
Xigris side effect was reported by a Physician from GERMANY on Feb 03, 2006. Male patient, 15 years of age, weighting 154.3 lb, was diagnosed with meningococcal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: circulatory collapse, condition aggravated, meningococcal sepsis, multi-organ failure, renal failure, respiratory failure. Xigris dosage: unknown. During the same period patient was treated with CLAFORAN, ARIVEN, NORADRENALINE, DORMICUM ROCHE, SUFENTA, HYDROCORTISONE, OMEPRAZOLE. Patient was hospitalized. Patient died on 01/29/2006.
Xigris Side Effects Report #5985922-2
Xigris side effect was reported by a Health Professional from UNITED STATES on Dec 05, 2008. Male patient, 72 years of age, weighting 173.7 lb, was diagnosed with cerebrovascular accident and was treated with Xigris. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, condition aggravated, pyrexia, unresponsive to stimuli, white blood cell count increased. Xigris dosage: unknown. During the same period patient was treated with LOVASTATIN, ASPIRIN, NICODERM CQ, SIMVASTATIN, ACETAMINOPHEN, NYSTATIN, MANNITOL. Patient died on 09/14/2008.
Xigris Side Effects Report #4692891-4
Xigris side effect was reported by a Consumer or non-health professional from on June 01, 2005. Male patient was treated with Xigris. After drug was administered, patient experienced the following side effects: condition aggravated, epistaxis, medical device complication, obstruction, pharyngeal haemorrhage, pneumothorax, respiratory disorder, thrombosis. Xigris dosage: unknown. During the same period patient was treated with NEXIUM, VASOPRESSINECTION, EPINEPHRINE, ZINACEF. Patient died on 03/13/2005.