Xigris and coagulopathy Patient Reports February 12, 2012

Xigris Side Effects Report #5170032-7
Xigris side effect was reported by a Physician from GERMANY on Dec 04, 2006. Female patient, 70 years of age, was diagnosed with toxic shock syndrome streptococcal and was treated with Xigris. After drug was administered, patient experienced the following side effects: brain stem haemorrhage, coagulopathy, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with HEPARIN. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4718881-0
Xigris side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on July 01, 2005. Female patient, 75 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, coma, subarachnoid haemorrhage, thrombocytopenia. Xigris dosage: 24 MG/KG/HR. During the same period patient was treated with HEPARIN, ACTRAPID, ADRENALINE, AMIODARONE, FLOLAN, GLUTAMINE, PROPOFOL, FENTANYL. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4752538-5
Xigris side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Aug 04, 2005. Female patient, 75 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, coma, subarachnoid haemorrhage, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, ACTRAPID, ADRENALINE, AMIODARONE, FLOLAN, GLUTAMINE, PROPOFOL, FENTANYL. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4821814-X
Xigris side effect was reported by a Physician from UNITED KINGDOM on Oct 13, 2005. Female patient, 76 years of age, weighting 154.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, ACETAMINOPHEN, HYDROCORTISONE, ANTIBIOTIC. Patient died on 09/29/2005.


Xigris Side Effects Report #4781777-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Sept 13, 2005. Female patient, 72 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, acute respiratory distress syndrome, blood creatine phosphokinase increased, blood urea increased, coagulopathy, condition aggravated, culture urine positive, escherichia infection, faeces discoloured. Xigris dosage: 24 MG/KG/HR. During the same period patient was treated with LOVENOX, DOPAMINE, ASPIRIN, FENTANYL, LORAZEPAM, QUININE, PANTOPRAZOLE. Patient recovered.

Xigris Side Effects Report #4870273-X
Xigris side effect was reported by a Physician from SPAIN on Nov 29, 2005. Male patient, 71 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal distension, coagulopathy, kaolin cephalin clotting time prolonged, multi-organ failure, peritoneal haemorrhage, splenic rupture. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5697133-9
Xigris side effect was reported by a Physician from UNITED STATES on Mar 27, 2008. Female patient, 65 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, haemorrhage. Xigris dosage: unknown. During the same period patient was treated with IMMUNOSUPPRESSIVE AGENTS, LEVOPHED. Patient died on 03/01/2008.

Xigris Side Effects Report #5140412-4
Xigris side effect was reported by a Health Professional from UNITED KINGDOM on Oct 05, 2006. Male patient, 64 years of age, weighting 196.2 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, haemorrhage intracranial, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, FENTANYL CITRATE, VECURONIUM BROMIDE, SALBUTAMOL, ERYTHROMYCIN, AUGMENTIN, ENOXAPARIN, HYDROCORTISONE. Patient recovered.

Xigris Side Effects Report #5051708-9
Xigris side effect was reported by a Pharmacist from UNITED STATES on July 12, 2006. Male patient, 62 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, haemorrhage. Xigris dosage: unknown. Patient recovered.


Xigris Side Effects Report #4614086-2
Xigris side effect was reported by a Physician from on Feb 25, 2005. Male patient, 34 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy. Xigris dosage: unknown. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4638058-7
Xigris side effect was reported by a Pharmacist from on Mar 28, 2005. Female patient, 32 years of age, weighting 169.8 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood creatine phosphokinase increased, blood creatinine increased, blood lactate dehydrogenase increased, coagulopathy, fasciitis. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSINECTION, DIPRIVAN, CLEOCIN, VANCOMYCIN, LEVAQUIN, GENTAMICIN. Patient died on 03/25/2005.

Xigris Side Effects Report #5241718-0
Xigris side effect was reported by a Physician from LEBANON on Feb 08, 2007. Female patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, condition aggravated, endocarditis , oliguria. Xigris dosage: unknown. Patient died on 01/01/2006.

Xigris Side Effects Report #5697122-4
Xigris side effect was reported by a Physician from UNITED STATES on Mar 27, 2008. Female patient, weighting 160.9 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, haemorrhage, thrombocytopenia. Xigris dosage: 24 UG, OTHER;8.7ML/HOUR. Patient recovered.

Xigris Side Effects Report #5735874-5
Xigris side effect was reported by a Physician from UNITED STATES on May 05, 2008. Female patient, weighting 160.9 lb, was diagnosed with sepsis , catheter related complication and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, haemorrhage, thrombocytopenia. Xigris dosage: 24 UG, OTHER;8.7ML/HOUR. During the same period patient was treated with HEPARIN. Patient recovered.


Xigris Side Effects Report #4588111-1
Xigris side effect was reported by a Physician from on Feb 01, 2005. Male patient was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, haemorrhage, platelet count decreased. Xigris dosage: unknown. Patient died on 01/01/2005.

Xigris Side Effects Report #4613235-X
Xigris side effect was reported by a Physician from on Mar 01, 2005. Male patient, weighting 132.3 lb, was diagnosed with sepsis , multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, international normalised ratio decreased, respiratory tract haemorrhage, thrombosis. Xigris dosage: unknown. During the same period patient was treated with MERONEM, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, DORMICUM, GAMMAGARD, FUROSEMIDE. Patient recovered.

Xigris Side Effects Report #4564647-4
Xigris side effect was reported by a Physician from on Jan 11, 2005. Male patient, 69 years of age, weighting 165.3 lb, was diagnosed with multi-organ failure, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood fibrinogen increased, coagulopathy, haematocrit decreased, haematuria, haemoglobin decreased, leukocytosis, petechiae, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, LINEZOLID, MEROPENEM, CIPROFLOXACIN, VORICONAZOLE, FUROSEMIDE, MANNITOL. Patient recovered.

Xigris Side Effects Report #4719083-4
Xigris side effect was reported by a Physician from POLAND on July 01, 2005. Male patient, 64 years of age, weighting 132.3 lb, was diagnosed with multi-organ failure, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiopulmonary failure, coagulopathy, gastrointestinal haemorrhage, international normalised ratio increased, respiratory tract haemorrhage. Xigris dosage: unknown. During the same period patient was treated with MERONMEN, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, MIDAZOLAM, GAMMAGARD. Patient died on 10/31/2004.

Xigris Side Effects Report #4608421-9
Xigris side effect was reported by a Physician from on Feb 22, 2005. Male patient, weighting 132.3 lb, was diagnosed with multi-organ failure, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, respiratory tract haemorrhage. Xigris dosage: unknown. During the same period patient was treated with MERONEM, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, DORMICUM, GAMMAGARD. Patient recovered.


Xigris Side Effects Report #4648367-3
Xigris side effect was reported by a Physician from on Apr 13, 2005. Male patient, weighting 132.3 lb, was diagnosed with multi-organ failure, sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, international normalised ratio decreased, respiratory tract haemorrhage. Xigris dosage: unknown. During the same period patient was treated with MERONEM, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, DORMICUM, GAMMARGARD. Patient recovered.

Xigris Side Effects Report #5796159-4
Xigris side effect was reported by a Physician from UNITED KINGDOM on June 17, 2008. Male patient, weighting 165.3 lb, was diagnosed with abdominal sepsis, sedation and was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, livedo reticularis, sepsis . Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE, TERLIPRESSIN, PIPERACILLIN AND TAZOBACTAM, METRONIDAZOLE, MORPHINE. Patient died on 03/15/2008.

Xigris Side Effects Report #4827730-1
Xigris side effect was reported by a Health Professional from AUSTRALIA on Oct 27, 2005. Male patient, 74 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: adverse event, coagulopathy, respiratory tract haemorrhage. Xigris dosage: unknown. Patient died on 01/01/2005.

Xigris Side Effects Report #5026171-4
Xigris side effect was reported by a Health Professional from UNITED STATES on May 24, 2006. Female patient, 47 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy, injection site haemorrhage. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4686728-7
Xigris side effect was reported by a Physician from on May 25, 2005. Female patient, 41 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: coagulopathy. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient recovered.