Xigris and cerebral haemorrhage Patient Reports February 12, 2012

Xigris Side Effects Report #4801897-3
Xigris side effect was reported by a Pharmacist from UNITED STATES on Oct 14, 2005. Male patient, 51 years of age, weighting 171.1 lb, was diagnosed with systemic inflammatory response syndrome and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, culture stool positive, enterococcal infection, renal failure, respiratory failure, shock. Xigris dosage: unknown. During the same period patient was treated with DOBUTAMINE, VASOPRESSIN, NOREPINEPHRINE, PANTOPRAZOLE, PRIMAXIN, METRONIDAZOLE, FLUCONAZOLE, BICARBONATE. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5485635-X
Xigris side effect was reported by a Physician from GERMANY on Oct 04, 2007. Female patient, 76 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac failure, cerebral haemorrhage, mydriasis. Xigris dosage: 24 MG/KG/HOUR. Patient died on 09/25/2007.

Xigris Side Effects Report #5486382-0
Xigris side effect was reported by a Physician from GERMANY on Oct 04, 2007. Female patient, 76 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac failure, cerebral haemorrhage, mydriasis. Xigris dosage: 24 MG/KG/HOUR. Patient died on 09/25/2007.

Xigris Side Effects Report #4579462-5
Xigris side effect was reported by a Consumer or non-health professional from on Jan 19, 2005. Male patient, 65 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, depressed level of consciousness, hydrocephalus , international normalised ratio increased, intracranial pressure increased, mydriasis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient died on 12/25/2004.


Xigris Side Effects Report #4718878-0
Xigris side effect was reported by a Physician from FRANCE on July 05, 2005. Male patient, 54 years of age, weighting 156.5 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, carbon dioxide abnormal, catheter site haemorrhage, cerebellar haemorrhage, cerebral haemorrhage, coma. Xigris dosage: unknown. During the same period patient was treated with HUMULIN, HEPARIN, ACUPAN, TAZOCILLINE, MIDAZOLAM, FLUCONAZOLE, HYDROCORTISONE, MORPHINE. Patient died on 05/03/2005.

Xigris Side Effects Report #5022700-5
Xigris side effect was reported by a Consumer or non-health professional from FRANCE on May 22, 2006. Male patient, 53 years of age, weighting 194.0 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, epistaxis, meningorrhagia, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with ASPEGIC, HYDROCORTISONE, NIMBEX, INSULIN, PERFALGAN, ALPRAZOLAM, LIORESAL, EZETROL. Patient died on 01/30/2006.

Xigris Side Effects Report #4600165-2
Xigris side effect was reported by a Physician from on Feb 16, 2005. Female patient, 51 years of age, weighting 149.9 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood disorder, cerebral haemorrhage, lung infection, multi-organ disorder, nervous system disorder, pupils unequal, renal failure acute, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, DOBUTAMINE, LIDOCAINE W. Patient was hospitalized. Patient died on 02/11/2005.

Xigris Side Effects Report #4618251-X
Xigris side effect was reported by a Physician from on Mar 03, 2005. Female patient, 51 years of age, weighting 149.9 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal mass, catheter site haemorrhage, cerebral haemorrhage, cholecystitis, coma, condition aggravated, depressed level of consciousness, disseminated intravascular coagulation. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, DOBUTAMINE, LIDOCAINE W, GLIPRESSINA, MERREM, ZITHROMAX, TARGOSID, METRONIDAZOLE. Patient was hospitalized. Patient died on 02/11/2005.

Xigris Side Effects Report #5528960-6
Xigris side effect was reported by a Physician from FRANCE on Nov 16, 2007. Male patient, 49 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. During the same period patient was treated with KARDEGIC, INSULINE, MIDAZOLAM, ADRENALINE, TIENAM, NEBCIN, INEXIUM. Patient died on 10/08/2007.


Xigris Side Effects Report #4546383-3
Xigris side effect was reported by a Consumer or non-health professional from on Dec 09, 2004. Male patient, 49 years of age, weighting 209.4 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: 24 MG/KG/HR. During the same period patient was treated with HYDROCORTISONE, TAZOCIN, NORADRENALINE, DOPEXAMINE. Patient died on 09/25/2004.

Xigris Side Effects Report #5496481-5
Xigris side effect was reported by a Physician from FRANCE on Oct 15, 2007. Male patient, 40 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. Patient died on 10/01/2007.

Xigris Side Effects Report #4781678-X
Xigris side effect was reported by a Health Professional from ICELAND on Sept 08, 2005. Male patient, 40 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, cerebral infarction, cerebral ischaemia, loss of consciousness, nervous system disorder. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4848696-4
Xigris side effect was reported by a Consumer or non-health professional from ICELAND on Nov 17, 2005. Male patient, 40 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, cerebral ischaemia, csf protein increased, loss of consciousness. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4964476-3
Xigris side effect was reported by a Consumer or non-health professional from FRANCE on Mar 23, 2006. Female patient, 23 years of age, weighting 202.8 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: 40 MG, DAILY (1/D), INTRAVENOUS. Patient recovered.


Xigris Side Effects Report #5030750-8
Xigris side effect was reported by a Consumer or non-health professional from FRANCE on June 06, 2006. Female patient, 23 years of age, weighting 202.8 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, quadriparesis. Xigris dosage: 40 MG, DAILY (1/D), INTRAVENOUS. During the same period patient was treated with MIDAZOLAM, SUFENTA. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4600059-2
Xigris side effect was reported by a Pharmacist from on Feb 16, 2005. Male patient, 17 years of age, weighting 165.3 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, adrenal cortex necrosis, adrenal haemorrhage, blood fibrinogen decreased, cerebral haemorrhage, nervous system disorder, petechiae. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE. Patient died on 01/01/2005.

Xigris Side Effects Report #4608419-0
Xigris side effect was reported by a Pharmacist from on Feb 18, 2005. Male patient, 17 years of age, weighting 165.3 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, adrenal haemorrhage, cerebral haemorrhage, haemorrhage intracranial, necrosis, petechiae, platelet count decreased, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE. Patient died on 01/01/2005.

Xigris Side Effects Report #5566687-5
Xigris side effect was reported by a Physician from ITALY on Dec 14, 2007. Male patient was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, coma. Xigris dosage: unknown. During the same period patient was treated with VANCOMYCIN HYDROCHLORIDE, ADRENALINE, NORADRENALINE, LEVOFLOXACIN, PIPERACILLIN W. Patient died on 10/30/2007.

Xigris Side Effects Report #5697134-0
Xigris side effect was reported by a Physician from ITALY on Mar 28, 2008. Male patient was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, thrombocytopenia. Xigris dosage: 0.024 MG/KG, AS NEEDED. During the same period patient was treated with NORADRENALINE, MIDAZOLAM, MORPHINE, VANCOMYCIN, METRONIDAZOLE, MEROPENEM, FLUCONAZOLE, FUROSEMIDE. Patient died on 03/05/2008.


Xigris Side Effects Report #5874242-2
Xigris side effect was reported by a Physician from GERMANY on Aug 27, 2008. Male patient, weighting 138.9 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, hypoxia. Xigris dosage: unknown. During the same period patient was treated with HEPARIN. Patient died on 05/18/2008.

Xigris Side Effects Report #5874253-7
Xigris side effect was reported by a Physician from GERMANY on Aug 27, 2008. Female patient, weighting 183.0 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , cerebral haemorrhage. Xigris dosage: 2.9 MG, EVERY HOUR (48 MG). During the same period patient was treated with HEPARIN, NORADRENALINE, VASOPRESSIN, EPINEPHRINE. Patient died on 01/21/2008.

Xigris Side Effects Report #5898196-8
Xigris side effect was reported by a Physician from INDIA on Sept 13, 2008. Female patient, 69 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, cerebral haemorrhage. Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE, DOPAMINE, VASOPRESSIN. Patient was hospitalized. Patient died on 09/12/2008.

Xigris Side Effects Report #4648368-5
Xigris side effect was reported by a Physician from on Apr 13, 2005. Male patient, 65 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood fibrinogen increased, cerebral haemorrhage, depressed level of consciousness, encephalopathy, hydrocephalus , international normalised ratio increased, intracranial pressure increased, mydriasis. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient died on 12/25/2004.

Xigris Side Effects Report #5573520-4
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 20, 2007. Female patient, 61 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, coma, hypoxia, no therapeutic response, respiratory distress, septic shock, subdural haematoma, unresponsive to stimuli, urine output increased. Xigris dosage: unknown. Patient died on 11/14/2007.


Xigris Side Effects Report #4570792-X
Xigris side effect was reported by a Consumer or non-health professional from on Jan 12, 2005. Male patient, 60 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: catheter site haemorrhage, cerebral haemorrhage, injection site haemorrhage, platelet count decreased. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4987932-0
Xigris side effect was reported by a Consumer or non-health professional from SPAIN on Apr 07, 2006. Female patient, 58 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5626283-8
Xigris side effect was reported by a Physician from UNITED STATES on Feb 05, 2008. Female patient, 57 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, disseminated intravascular coagulation. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSIN, OXYGEN. Patient died on 12/01/2007.

Xigris Side Effects Report #5735869-1
Xigris side effect was reported by a Physician from UNITED STATES on May 05, 2008. Female patient, 57 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, disseminated intravascular coagulation, sepsis . Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSIN, OXYGEN, PREVACID. Patient died on 01/04/2008.

Xigris Side Effects Report #4665093-5
Xigris side effect was reported by a Physician from on Apr 28, 2005. Female patient, 57 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. Patient died.


Xigris Side Effects Report #5961367-6
Xigris side effect was reported by a Physician from SPAIN on Nov 07, 2008. Male patient, 56 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haemorrhage, epistaxis, thrombocytopenia, wound haemorrhage. Xigris dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with HEPARIN. Patient died.

Xigris Side Effects Report #6037332-X
Xigris side effect was reported by a Physician from SPAIN on Jan 07, 2009. Male patient, 56 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haemorrhage, epistaxis, thrombocytopenia, wound haemorrhage. Xigris dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with HEPARIN. Patient died on 06/16/2008.

Xigris Side Effects Report #4614079-5
Xigris side effect was reported by a Physician from on Mar 02, 2005. Male patient, 56 years of age, weighting 141.1 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, intraventricular haemorrhage, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with VASOPRESSORS, NOREPINERPHRINE. Patient died.

Xigris Side Effects Report #5604764-0
Xigris side effect was reported by a Physician from FRANCE on Jan 16, 2008. Female patient, 55 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4546441-3
Xigris side effect was reported by a Physician from on Dec 13, 2004. Female patient, 54 years of age, weighting 136.7 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal abscess, activated partial thromboplastin time shortened, acute pulmonary oedema, basophilia, blood bilirubin increased, brain oedema, cerebral haemorrhage, metastases to central nervous system, mydriasis. Xigris dosage: unknown. During the same period patient was treated with PARECOXIB, AUGMENTINE, IMIPENEM, AMIKACINE, FRAXIPARINE, KETOROLAC, EPOGEN, HYDROCORTISONE. Patient was hospitalized. Patient died on 11/13/2004.


Xigris Side Effects Report #4883823-4
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 28, 2005. Male patient, 54 years of age, weighting 176.4 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cardiac arrest , cerebral haemorrhage, convulsion, international normalised ratio increased, pyothorax, septic embolus. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, DILANTIN, CEFTRIAXONE, DIFLUCAN, NAFCILLIN, FENTANYL CITRATE, PEPCID, ATROVENT. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4886472-7
Xigris side effect was reported by a Pharmacist from UNITED STATES on Jan 05, 2006. Male patient, 54 years of age, weighting 176.4 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood potassium increased, cardiac arrest , cerebral haemorrhage, convulsion, empyema, endocarditis , septic embolus. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, DILANTIN, CEFTRIAXONE, DIFLUCAN, NAFICILLIN, FENTANYL CITRATE, PEPCID, ATROVENT. Patient was hospitalized. Patient died on 08/02/2005.

Xigris Side Effects Report #4599912-8
Xigris side effect was reported by a Physician from on Feb 11, 2005. Male patient, 53 years of age, weighting 143.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood calcium increased, blood sodium increased, brain oedema, brain scan abnormal, cerebral haemorrhage, haemoglobin decreased, international normalised ratio decreased. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, CEFTRIAXONE, METRONIDAZOLE, CHLORAMPHENICOL, ALBUMIN NOS, HYDROCORTISONE, VITAMIN K, CAPTOPRIL. Patient was hospitalized and became disabled. Patient died.

Xigris Side Effects Report #4638492-5
Xigris side effect was reported by a Physician from on Mar 29, 2005. Male patient, 53 years of age, weighting 143.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOL, CEFTRIAXONE, METRONIDAZOLE, CHLORAMPHENICOL, TRAMADOL, ALBUMIN NOS, HYDROCORTISONE, VITMAIN K. Patient was hospitalized and became disabled. Patient died.

Xigris Side Effects Report #4665001-7
Xigris side effect was reported by a Physician from on May 02, 2005. Male patient, 53 years of age, weighting 143.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood sodium increased, brain oedema, cerebral haemorrhage, haemoglobin decreased, intraventricular haemorrhage, platelet count increased, prothrombin time prolonged, white blood cell count increased. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOL, CEFTRIAXONE, METRONIDAZOLE, CHLORAMPHENICOL, TRAMADOL, ALBUMIN NOS, HYDROCORTISONE, VITAMIN K. Patient was hospitalized and became disabled. Patient died on 01/20/2005.


Xigris Side Effects Report #5052115-5
Xigris side effect was reported by a Physician from SPAIN on June 19, 2006. Male patient, 52 years of age, weighting 165.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal pain upper, cerebral haemorrhage, diabetes insipidus , hypotension, hypothermia , multi-organ failure, pneumonia , respiratory failure. Xigris dosage: unknown. During the same period patient was treated with MIDAZOLAM HYDROCHLORIDE, ANTIBIOTICS, CORTICOSTEROIDS, DOPAMINE, NORADRENALINE, PANTOPRAZOLE. Patient was hospitalized. Patient died on 04/01/2006.

Xigris Side Effects Report #4815032-9
Xigris side effect was reported by a Health Professional from INDIA on Oct 07, 2005. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time, activated partial thromboplastin time prolonged, blood creatinine increased, cerebral haemorrhage, international normalised ratio increased, loss of consciousness, mydriasis, peritoneal dialysis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with SEDATIVE, MUSCLE RELAXANT, ANTIBIOTIC. Patient was hospitalized. Patient died on 09/28/2005.

Xigris Side Effects Report #4822100-4
Xigris side effect was reported by a Consumer or non-health professional from INDIA on Oct 14, 2005. Female patient, 52 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood creatine increased, cerebral haemorrhage, international normalised ratio increased, loss of consciousness, mydriasis, peritoneal dialysis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with SEDATIVE, MUSCLE RELAXANT, ANTIBIOTIC. Patient was hospitalized. Patient died on 09/28/2005.

Xigris Side Effects Report #5030002-6
Xigris side effect was reported by a Physician from SPAIN on May 26, 2006. Male patient, 52 years of age, weighting 165.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal pain upper, cerebral haemorrhage, diabetes insipidus , hypotension, hypothermia , multi-organ failure, nosocomial infection, pneumonia , respiratory failure. Xigris dosage: unknown. During the same period patient was treated with MIDAZOLAM, ANTIBIOTICS. Patient was hospitalized. Patient died on 04/01/2006.

Xigris Side Effects Report #5284632-7
Xigris side effect was reported by a Physician from FRANCE on Mar 23, 2007. Male patient, 51 years of age, weighting 138.9 lb, was diagnosed with sepsis , septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. During the same period patient was treated with LASIX, HYPNOVEL, NIMBEX, SUFENTA, NORADRENALINE. Patient died on 01/28/2007.

Xigris Side Effects Report #5365395-3
Xigris side effect was reported by a Physician from FRANCE on June 15, 2007. Male patient, 51 years of age, weighting 138.9 lb, was diagnosed with sepsis , septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, ischaemic stroke, meningorrhagia. Xigris dosage: unknown. During the same period patient was treated with LASIX, HYPNOVEL, NIMBEX, SUFENTA, NORADRENALINE, TAZOCILLINE, CIFLOX, ZYVOX. Patient died on 01/28/2007.

Xigris Side Effects Report #4608739-X
Xigris side effect was reported by a Physician from on Feb 21, 2005. Female patient, 51 years of age, weighting 149.9 lb, was diagnosed with sepsis , septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, condition aggravated, depressed level of consciousness, haemorrhage intracranial, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, DOBUTAMINE, LIDOCAINE W, GLIPRESSINA, MERREM, ZITHROMAX, TARGOSID. Patient was hospitalized. Patient died on 02/11/2005.

Xigris Side Effects Report #4777995-X
Xigris side effect was reported by a Physician from BELGIUM on Sept 06, 2005. Female patient, 51 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, intestinal perforation, lactic acidosis, necrotising fasciitis, renal failure acute, respiratory failure, septic shock, thrombocytopenia. Xigris dosage: 35.136 MG DAY. During the same period patient was treated with MIDAZOLAM, NOREPINEPHERINE. Patient was hospitalized. Patient died on 07/02/2005.

Xigris Side Effects Report #4815095-0
Xigris side effect was reported by a Physician from INDIA on Oct 11, 2005. Male patient, 49 years of age, weighting 121.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood creatinine increased, cerebral haemorrhage, convulsion, implant site haemorrhage. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4819013-0
Xigris side effect was reported by a Physician from INDIA on Oct 11, 2005. Male patient, 49 years of age, weighting 121.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, convulsion, feeding tube complication. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.


Xigris Side Effects Report #4714095-9
Xigris side effect was reported by a Physician from UNITED KINGDOM on June 24, 2005. Female patient, 46 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood sodium decreased, cerebral haemorrhage, hemiparesis, nervous system disorder, sedation, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with SUXAMETHONIUM, MIDAZOLAM HYDROCHLORIDE, AMIODARONE, NORADRENALINE, DOPEXAMINE, FENTANYL, CLARITHROMYCIN, CEFOTAXIME. Patient was hospitalized and became disabled. Patient recovered.

Xigris Side Effects Report #5324858-7
Xigris side effect was reported by a Physician from MEXICO on May 03, 2007. Male patient, 28 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient died on 03/07/2007.

Xigris Side Effects Report #5731694-6
Xigris side effect was reported by a Physician from UNITED STATES on May 01, 2008. Male patient, 21 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: accidental overdose, cerebral haemorrhage, encephalomalacia. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5786055-0
Xigris side effect was reported by a Physician from UNITED STATES on June 16, 2008. Male patient, 21 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, encephalomalacia. Xigris dosage: unknown. Patient died on 03/01/2008.

Xigris Side Effects Report #4638485-8
Xigris side effect was reported by a Consumer or non-health professional from on Mar 24, 2005. Female patient, 66 years of age, weighting 143.3 lb, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, cerebral haemorrhage. Xigris dosage: 15.6 ML/HR. During the same period patient was treated with METRONIDAZOLE, MEROPENEM, TEICOPLANIN, FLUCONAZOLE, CIPROFLOXACIN. Patient died.

Xigris Side Effects Report #5797935-4
Xigris side effect was reported by a Physician from SPAIN on June 18, 2008. Male patient, 60 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal distension, cerebellar infarction, cerebral haemorrhage, intestinal perforation, peritonitis, platelet count decreased, respiratory disorder. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, ONDASETRON, FENTANYL, NOLOTIL, ENANTYUM, LACTULOSE, TRADONAL, DACORTIN. Patient was hospitalized. Patient died on 06/18/2008.

Xigris Side Effects Report #5804633-7
Xigris side effect was reported by a Physician from SPAIN on June 27, 2008. Male patient, 60 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal distension, cerebral haemorrhage, haemorrhagic cerebral infarction, intestinal perforation, peritonitis, respiratory disorder, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, ONDASETRON, FENTANYL, NOLOTIL, ENANTYUM, LACTULOSE, TRADONAL, DACORTIN. Patient was hospitalized. Patient died on 06/18/2008.

Xigris Side Effects Report #6037336-7
Xigris side effect was reported by a Physician from SPAIN on Jan 12, 2009. Male patient, 60 years of age, was diagnosed with multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, haemorrhagic cerebral infarction, peritonitis, respiratory disorder, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, ONDASETRON, FENTANYL, NOLOTIL, ENANTYUM, LACTULOSE, TRADONAL, DACORTIN. Patient was hospitalized. Patient died on 06/18/2008.

Xigris Side Effects Report #4629825-4
Xigris side effect was reported by a Health Professional from on Mar 17, 2005. Female patient, 58 years of age, was diagnosed with multi-organ failure, urosepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, platelet count decreased. Xigris dosage: unknown. Patient died on 02/23/2005.

Xigris Side Effects Report #4642795-8
Xigris side effect was reported by a Physician from on Apr 04, 2005. Female patient, 58 years of age, was diagnosed with multi-organ failure, urosepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, platelet count decreased, pupil fixed. Xigris dosage: unknown. During the same period patient was treated with ADRENALINE, NORADRENALINE. Patient died on 02/23/2005.


Xigris Side Effects Report #6083841-7
Xigris side effect was reported by a Physician from FRANCE on Feb 13, 2009. Male patient, weighting 154.3 lb, was diagnosed with multi-organ failure, nutritional support , shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, hepatic function abnormal. Xigris dosage: unknown. During the same period patient was treated with OLICLINOMEL, TIENAM, CIFLOX, VFEND, ZYVOXID, INIPOMP, NORADRENALINE. Patient died on 10/11/2008.

Xigris Side Effects Report #6105403-5
Xigris side effect was reported by a Physician from UNITED STATES on Mar 04, 2009. Female patient, 54 years of age, weighting 188.9 lb, was diagnosed with ischaemic stroke and was treated with Xigris. After drug was administered, patient experienced the following side effects: brain herniation, brain oedema, cerebral haemorrhage, cerebral infarction, intracranial pressure increased, stroke in evolution. Xigris dosage: unknown. During the same period patient was treated with LISINOPRIL, NEXIUM, IBUPROPHEN, LIPITOR, ASPIRIN, NORVASC, TYLENOL, LOVENOX. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5319978-7
Xigris side effect was reported by a Physician from UNITED KINGDOM on May 03, 2007. Female patient, 62 years of age, weighting 154.3 lb, was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage. Xigris dosage: unknown. Patient died.