Xigris and brain death Patient Reports February 12, 2012

Xigris Side Effects Report #5117543-8
Xigris side effect was reported by a Physician from ARGENTINA on Sept 07, 2006. Female patient, 35 years of age, was diagnosed with urosepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, nervous system disorder, platelet count decreased, vasculitis . Xigris dosage: unknown. During the same period patient was treated with VALPROIC ACID, NORADRENALINE, FUROSEMIDE, REMIFENTANIL, MIDAZOLAM HYDROCHLORIDE, PIPERACILLIN W, AMIKACIN, RANITIDINE. Patient was hospitalized. Patient died on 09/05/2006.

Xigris Side Effects Report #5141768-9
Xigris side effect was reported by a Physician from ARGENTINA on Oct 12, 2006. Female patient, 35 years of age, was diagnosed with urosepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, intraventricular haemorrhage, thrombocytopenia, vasculitis cerebral. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, VALPROIC ACID, NORADRENALINE, FUROSEMIDE, REMIFENTANIL, MIDAZOLAM, PIPERACILLIN W, AMIKACIN. Patient was hospitalized. Patient died on 09/05/2006.

Xigris Side Effects Report #5154982-3
Xigris side effect was reported by a Physician from ARGENTINA on Sept 07, 2006. Female patient, 35 years of age, was diagnosed with urosepsis, convulsion, intubation, sleep disorder , antibiotic prophylaxis and was treated with Xigris. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with VALPROIC ACID, NORADRENALINE, FUROSEMIDE, REMIFENTANIL, MIDAZOLAM, PIPERACILLIN W. Patient was hospitalized. Patient died on 09/05/2006.

Xigris Side Effects Report #4579462-5
Xigris side effect was reported by a Consumer or non-health professional from on Jan 19, 2005. Male patient, 65 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, depressed level of consciousness, hydrocephalus , international normalised ratio increased, intracranial pressure increased, mydriasis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient died on 12/25/2004.


Xigris Side Effects Report #4571111-5
Xigris side effect was reported by a Physician from on Jan 19, 2005. Male patient, 60 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebellar haemorrhage. Xigris dosage: unknown. Patient died on 12/25/2004.

Xigris Side Effects Report #4600165-2
Xigris side effect was reported by a Physician from on Feb 16, 2005. Female patient, 51 years of age, weighting 149.9 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood disorder, cerebral haemorrhage, lung infection, multi-organ disorder, nervous system disorder, pupils unequal, renal failure acute, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, DOBUTAMINE, LIDOCAINE W. Patient was hospitalized. Patient died on 02/11/2005.

Xigris Side Effects Report #4618251-X
Xigris side effect was reported by a Physician from on Mar 03, 2005. Female patient, 51 years of age, weighting 149.9 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal mass, catheter site haemorrhage, cerebral haemorrhage, cholecystitis, coma, condition aggravated, depressed level of consciousness, disseminated intravascular coagulation. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, DOBUTAMINE, LIDOCAINE W, GLIPRESSINA, MERREM, ZITHROMAX, TARGOSID, METRONIDAZOLE. Patient was hospitalized. Patient died on 02/11/2005.

Xigris Side Effects Report #4600059-2
Xigris side effect was reported by a Pharmacist from on Feb 16, 2005. Male patient, 17 years of age, weighting 165.3 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, adrenal cortex necrosis, adrenal haemorrhage, blood fibrinogen decreased, cerebral haemorrhage, nervous system disorder, petechiae. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE. Patient died on 01/01/2005.

Xigris Side Effects Report #4648368-5
Xigris side effect was reported by a Physician from on Apr 13, 2005. Male patient, 65 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood fibrinogen increased, cerebral haemorrhage, depressed level of consciousness, encephalopathy, hydrocephalus , international normalised ratio increased, intracranial pressure increased, mydriasis. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE. Patient died on 12/25/2004.


Xigris Side Effects Report #4932194-3
Xigris side effect was reported by a Pharmacist from UNITED STATES on Feb 08, 2006. Female patient, 65 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: convulsion, haemorrhage intracranial. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4599912-8
Xigris side effect was reported by a Physician from on Feb 11, 2005. Male patient, 53 years of age, weighting 143.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood calcium increased, blood sodium increased, brain oedema, brain scan abnormal, cerebral haemorrhage, haemoglobin decreased, international normalised ratio decreased. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, CEFTRIAXONE, METRONIDAZOLE, CHLORAMPHENICOL, ALBUMIN NOS, HYDROCORTISONE, VITAMIN K, CAPTOPRIL. Patient was hospitalized and became disabled. Patient died.

Xigris Side Effects Report #5052115-5
Xigris side effect was reported by a Physician from SPAIN on June 19, 2006. Male patient, 52 years of age, weighting 165.3 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: abdominal pain upper, cerebral haemorrhage, diabetes insipidus , hypotension, hypothermia , multi-organ failure, pneumonia , respiratory failure. Xigris dosage: unknown. During the same period patient was treated with MIDAZOLAM HYDROCHLORIDE, ANTIBIOTICS, CORTICOSTEROIDS, DOPAMINE, NORADRENALINE, PANTOPRAZOLE. Patient was hospitalized. Patient died on 04/01/2006.

Xigris Side Effects Report #4546382-1
Xigris side effect was reported by a Health Professional from on Dec 09, 2004. Male patient, 49 years of age, weighting 209.4 lb, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: bone disorder, brain oedema, haemodialysis, haemorrhage intracranial, hyperglycaemia, mydriasis, pancreatic necrosis, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, NORADRENALINE, DOPEXAMINE, PROPOFOL, ALFENTANIL, ACTRAPID, MEROPENEM, HYDROCORTISONE. Patient was hospitalized. Patient died on 09/25/2004.

Xigris Side Effects Report #5253413-2
Xigris side effect was reported by a Physician from UNITED STATES on Feb 21, 2007. Male patient, 47 years of age, was diagnosed with sepsis  and was treated with Xigris. Xigris dosage: unknown. Patient died on 02/14/2007.


Xigris Side Effects Report #4771038-X
Xigris side effect was reported by a Consumer or non-health professional from INDIA on Aug 30, 2005. Female patient, 24 years of age, was diagnosed with sepsis  and was treated with Xigris. After drug was administered, patient experienced the following side effects: convulsion, haematuria, haemorrhage intracranial, loss of consciousness, upper gastrointestinal haemorrhage. Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE, DOPAMINE, ANTIBIOTICS. Patient was hospitalized. Patient died on 08/31/2005.

Xigris Side Effects Report #4629825-4
Xigris side effect was reported by a Health Professional from on Mar 17, 2005. Female patient, 58 years of age, was diagnosed with multi-organ failure, urosepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, platelet count decreased. Xigris dosage: unknown. Patient died on 02/23/2005.

Xigris Side Effects Report #5797929-9
Xigris side effect was reported by a Physician from MEXICO on June 18, 2008. Female patient, 38 years of age, weighting 132.3 lb, was diagnosed with abdominal sepsis, prophylaxis and was treated with Xigris. After drug was administered, patient experienced the following side effects: blood pressure fluctuation, haemorrhage intracranial, post procedural haemorrhage. Xigris dosage: unknown. During the same period patient was treated with CLEXANE. Patient was hospitalized. Patient died.

Xigris Side Effects Report #5109450-1
Xigris side effect was reported by a Pharmacist from CANADA on Sept 01, 2006. Male patient, 48 years of age, was treated with Xigris. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #5117642-0
Xigris side effect was reported by a Pharmacist from CANADA on Sept 07, 2006. Male patient, 48 years of age, was treated with Xigris. Xigris dosage: unknown. Patient died.


Xigris Side Effects Report #5140433-1
Xigris side effect was reported by a Consumer or non-health professional from FRANCE on Oct 04, 2006. Female patient, 40 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: bradycardia, haemodynamic instability, liver disorder, multi-organ failure, nervous system disorder, renal disorder, respiratory disorder, rhabdomyolysis. Xigris dosage: unknown. During the same period patient was treated with CYMEVAN, WELLVONE, PROGRAF, BACTRIM, IMURAN, CEFIXIME CHEWABLE, CORTICOSTEROIDS. Patient was hospitalized. Patient died on 07/24/2006.