Xigris and activated partial thromboplastin time prolonged Patient Reports February 12, 2012

Xigris Side Effects Report #5383276-6
Xigris side effect was reported by a Physician from UNITED STATES on July 05, 2007. Male patient, 75 years of age, was diagnosed with systemic inflammatory response syndrome, thrombosis prophylaxis and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, prothrombin time prolonged, subarachnoid haemorrhage. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, ASPIRIN. Patient died on 04/08/2007.

Xigris Side Effects Report #4579397-8
Xigris side effect was reported by a Health Professional from on Jan 21, 2005. Female patient, 81 years of age, weighting 183.0 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haematocrit decreased, haemoglobin decreased, haemoptysis, platelet count decreased, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, LOVENOX, NOREPINEPHRINE BITARTRATE. Patient died on 01/04/2005.

Xigris Side Effects Report #4872684-5
Xigris side effect was reported by a Physician from ITALY on Dec 21, 2005. Male patient, 78 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haematoma, condition aggravated, convulsion, haemorrhage intracranial, infusion related reaction, international normalised ratio increased, prothrombin time prolonged, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, NOREPINEPHRINE BITARTRATE, DOBUTAMINE. Patient was hospitalized. Patient died on 09/05/2005.

Xigris Side Effects Report #4549348-0
Xigris side effect was reported by a Physician from on Dec 20, 2004. Female patient, 76 years of age, weighting 154.3 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, antithrombin iii decreased, blood fibrinogen increased, disseminated intravascular coagulation, epistaxis, fibrin d dimer increased, haemoglobin decreased, injection site haemorrhage, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with ANTITHROMBIN III, HEPARIN, MIDAZOLAM, CISATRACURIUM, FENTANYL, NORADRENALINE, DOPAMINE, DOBUTAMINE. Patient died on 12/16/2004.

Xigris Side Effects Report #5409678-7
Xigris side effect was reported by a Physician from UNITED STATES on Aug 02, 2007. Female patient, 52 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulation factor xi level decreased, coagulation factor xii level decreased, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient recovered.

Xigris Side Effects Report #4995381-4
Xigris side effect was reported by a Physician from UNITED STATES on Apr 18, 2006. Female patient, 50 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, platelet count decreased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5299598-3
Xigris side effect was reported by a Physician from UNITED STATES on Apr 10, 2007. Male patient, 46 years of age, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with PLASMA. Patient recovered.

Xigris Side Effects Report #4994344-2
Xigris side effect was reported by a Physician from UNITED KINGDOM on Apr 19, 2006. Female patient, 23 years of age, weighting 130.1 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, alanine aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, gamma-glutamyltransferase increased, pancytopenia, puncture site haemorrhage. Xigris dosage: unknown. During the same period patient was treated with VANCOMYCIN, ABELCET, ACYCLOVIR, MEROPENEM, HYDROCORTISONE, NORADRENALINE, MORPHINE. Patient recovered.

Xigris Side Effects Report #4600059-2
Xigris side effect was reported by a Pharmacist from on Feb 16, 2005. Male patient, 17 years of age, weighting 165.3 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, adrenal cortex necrosis, adrenal haemorrhage, blood fibrinogen decreased, cerebral haemorrhage, nervous system disorder, petechiae. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE. Patient died on 01/01/2005.

Xigris Side Effects Report #4608419-0
Xigris side effect was reported by a Pharmacist from on Feb 18, 2005. Male patient, 17 years of age, weighting 165.3 lb, was diagnosed with septic shock and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, adrenal haemorrhage, cerebral haemorrhage, haemorrhage intracranial, necrosis, petechiae, platelet count decreased, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE. Patient died on 01/01/2005.

Xigris Side Effects Report #4929323-4
Xigris side effect was reported by a Physician from UNITED STATES on Feb 01, 2006. Male patient, 87 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: acquired haemophilia, activated partial thromboplastin time prolonged, factor viii inhibition, fall

, gastrointestinal haemorrhage, haemarthrosis, haematocrit decreased, haematuria, haemoglobin decreased. Xigris dosage: unknown. Patient was hospitalized. Patient died on 03/03/2005.

Xigris Side Effects Report #5247723-2
Xigris side effect was reported by a Physician from UNITED STATES on Feb 19, 2007. Female patient, 82 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, hepatic enzyme abnormal, international normalised ratio increased, platelet count decreased, sepsis

. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient died on 12/12/2006.

Xigris Side Effects Report #4870183-8
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 14, 2005. Female patient, 81 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemoglobin decreased, international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with CEFOTETAN, HEPARIN, NOREPINEPHRINE BITARTRATE, ALBUMIN. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4562954-2
Xigris side effect was reported by a Physician from on Jan 10, 2005. Male patient, 80 years of age, weighting 165.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, convulsion, haemorrhage intracranial, incision site haemorrhage, international normalised ratio decreased, platelet count decreased, prothrombin time prolonged, upper gastrointestinal haemorrhage, wound haemorrhage. Xigris dosage: unknown. During the same period patient was treated with PIPERACILLIN W, MEROPENEM, METROGYL, PANTOPRAZOLE, LASIX, MANNITOL, TAXIM. Patient died on 12/30/2004.

Xigris Side Effects Report #4600095-6
Xigris side effect was reported by a Physician from on Feb 11, 2005. Male patient, 80 years of age, weighting 165.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, catheter site haemorrhage, convulsion, haemorrhage intracranial, incision site haemorrhage, international normalised ratio increased, platelet count decreased, prothrombin time prolonged, upper gastrointestinal haemorrhage. Xigris dosage: unknown. During the same period patient was treated with PIPERACILLIN W, MEROPENEM, METROGYL, PANTOPRAZOLE, LASIX, MANNITOL, TAXIM. Patient died on 12/30/2004.

Xigris Side Effects Report #5505422-3
Xigris side effect was reported by a Physician from UNITED STATES on Oct 26, 2007. Female patient, 79 years of age, weighting 198.4 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, disseminated intravascular coagulation. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4734250-1
Xigris side effect was reported by a Pharmacist from UNITED STATES on July 07, 2005. Male patient, 78 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, c-reactive protein increased, immune system disorder, international normalised ratio increased, pyrexia, red blood cell sedimentation rate increased. Xigris dosage: unknown. During the same period patient was treated with LOTREL, ASPIRIN, LASIX, ALLOPURINOL, PREVACID, LEVOPHED, ATIVAN. Patient recovered.

Xigris Side Effects Report #5017139-2
Xigris side effect was reported by a Physician from UNITED STATES on May 04, 2006. Male patient, 77 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, condition aggravated. Xigris dosage: unknown. Patient died on 05/01/2006.

Xigris Side Effects Report #4821814-X
Xigris side effect was reported by a Physician from UNITED KINGDOM on Oct 13, 2005. Female patient, 76 years of age, weighting 154.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, multi-organ failure. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, ACETAMINOPHEN, HYDROCORTISONE, ANTIBIOTIC. Patient died on 09/29/2005.

Xigris Side Effects Report #4957338-9
Xigris side effect was reported by a Pharmacist from UNITED STATES on Mar 15, 2006. Female patient, 76 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiac arrest

, cardio-respiratory arrest, hypotension, international normalised ratio increased, laboratory test interference, pneumothorax, respiratory failure. Xigris dosage: unknown. Patient died on 03/08/2006.

Xigris Side Effects Report #5253408-9
Xigris side effect was reported by a Physician from SPAIN on Feb 16, 2007. Male patient, 73 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, platelet count decreased. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #5267394-9
Xigris side effect was reported by a Physician from SPAIN on Mar 07, 2007. Male patient, 73 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5968410-9
Xigris side effect was reported by a Physician from UNITED STATES on Nov 17, 2008. Female patient, 72 years of age, was diagnosed with sepsis

, mechanical ventilation and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with OXYGEN. Patient recovered.

Xigris Side Effects Report #4781777-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Sept 13, 2005. Female patient, 72 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, acute respiratory distress syndrome, blood creatine phosphokinase increased, blood urea increased, coagulopathy, condition aggravated, culture urine positive, escherichia infection, faeces discoloured. Xigris dosage: 24 MG/KG/HR. During the same period patient was treated with LOVENOX, DOPAMINE, ASPIRIN, FENTANYL, LORAZEPAM, QUININE, PANTOPRAZOLE. Patient recovered.

Xigris Side Effects Report #4824526-1
Xigris side effect was reported by a Health Professional from UNITED KINGDOM on Oct 22, 2005. Male patient, 72 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE, DOBUTAMINE, HEPARIN. Patient recovered.

Xigris Side Effects Report #4791673-2
Xigris side effect was reported by a Physician from UNITED KINGDOM on Sept 16, 2005. Female patient, 70 years of age, weighting 121.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood culture positive, international normalised ratio increased, platelet count decreased, pseudomonas infection, sputum culture positive. Xigris dosage: unknown. During the same period patient was treated with HYDROCORTISONE, NORADRENALINE, TAZOCIN, METRONIDAZOLE, CEFTAZIDIME. Patient died on 09/08/2005.

Xigris Side Effects Report #4806759-3
Xigris side effect was reported by a Consumer or non-health professional from ITALY on Oct 03, 2005. Female patient, 68 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemoglobin decreased, haemothorax, platelet count decreased, prothrombin time prolonged, red blood cell count decreased. Xigris dosage: 37.4 MG. During the same period patient was treated with GABEXATE, SOLDESAM, DIFLUCAN, TRENTAL, FLUIMUCIL, OMEPRAZOLE, ASCORBIC ACID, ISOPTION. Patient was hospitalized. Patient died on 09/20/2005.

Xigris Side Effects Report #4764484-1
Xigris side effect was reported by a Physician from UNITED STATES on Aug 22, 2005. Female patient, 64 years of age, weighting 138.9 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood ph decreased, haematocrit decreased, haemoglobin decreased, international normalised ratio increased, oxygen saturation decreased, pco2 decreased, platelet count decreased, septic shock. Xigris dosage: unknown. During the same period patient was treated with NOREPINEPHRINE, VALSOPRESSINECTION, ASPIRIN, SEVELAMER, CILASTATIN W, ALLOPURINOL, LEVOFLOXACIN, HYDROCHLROTISONE. Patient died on 08/17/2005.

Xigris Side Effects Report #5202321-1
Xigris side effect was reported by a Physician from UNITED KINGDOM on Dec 29, 2006. Female patient, 61 years of age, weighting 176.4 lb, was diagnosed with sepsis

, analgesic effect, sedation and was treated with Xigris. After drug was administered, patient experienced the following side effects: accidental overdose, activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: 2.304 MG/KG, UNK. During the same period patient was treated with CIPROFLOXACIN, PENICILLIN G, NORADRENALINE, FENTANYL TRANSDERMAL SYSTEM, MIDAZOLAM HYDROCHLORIDE. Patient recovered.

Xigris Side Effects Report #5338446-X
Xigris side effect was reported by a Physician from IRELAND on May 22, 2007. Female patient, 61 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, platelet count decreased. Xigris dosage: 1.44 MG, EVERY HOUR. Patient died on 03/08/2007.

Xigris Side Effects Report #5349501-2
Xigris side effect was reported by a Physician from IRELAND on May 30, 2007. Female patient, 61 years of age, weighting 132.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, multi-organ failure, sepsis

. Xigris dosage: 1.44 MG, EVERY HOUR. During the same period patient was treated with VENTOLIN, SPIRIVA, AMITRIPTYLINE, ZOLPIDEM TARTRATE. Patient died on 03/08/2007.

Xigris Side Effects Report #5113939-9
Xigris side effect was reported by a Physician from UNITED KINGDOM on Sept 03, 2006. Male patient, 61 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, prothrombin time prolonged, thrombocytopenia. Xigris dosage: unknown. During the same period patient was treated with NORADRENALINE. Patient recovered.

Xigris Side Effects Report #5031391-9
Xigris side effect was reported by a Pharmacist from UNITED KINGDOM on May 31, 2006. Female patient, 61 years of age, weighting 143.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: accidental overdose, activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4746254-3
Xigris side effect was reported by a Health Professional from UNITED STATES on Aug 03, 2005. Female patient, 60 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSINECTION, DOPAMINE, HEPARN. Patient recovered.

Xigris Side Effects Report #4898950-5
Xigris side effect was reported by a Pharmacist from UNITED STATES on Jan 17, 2006. Female patient, 58 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, hepatic failure, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, VASOPRESSINECTION, DOPAMINE, HEPARIN. Patient died on 12/30/2005.

Xigris Side Effects Report #5740413-9
Xigris side effect was reported by a Physician from SPAIN on May 06, 2008. Male patient, 56 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, thrombocytopenia, wound haemorrhage. Xigris dosage: 0.024 MG/KG, EVERY HOUR. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5961367-6
Xigris side effect was reported by a Physician from SPAIN on Nov 07, 2008. Male patient, 56 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haemorrhage, epistaxis, thrombocytopenia, wound haemorrhage. Xigris dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with HEPARIN. Patient died.

Xigris Side Effects Report #6037332-X
Xigris side effect was reported by a Physician from SPAIN on Jan 07, 2009. Male patient, 56 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cerebral haemorrhage, epistaxis, thrombocytopenia, wound haemorrhage. Xigris dosage: 0.024 MG/KG, EVERY HOUR. During the same period patient was treated with HEPARIN. Patient died on 06/16/2008.

Xigris Side Effects Report #5102327-7
Xigris side effect was reported by a Pharmacist from UNITED STATES on Aug 22, 2006. Female patient, 54 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with HEPARIN. Patient recovered.

Xigris Side Effects Report #4871521-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Dec 16, 2005. Male patient, 54 years of age, weighting 166.9 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiac arrest

, haematocrit decreased, haemodialysis, international normalised ratio increased, thrombocytopenia, ventricular fibrillation, wound haemorrhage. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4886472-7
Xigris side effect was reported by a Pharmacist from UNITED STATES on Jan 05, 2006. Male patient, 54 years of age, weighting 176.4 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood potassium increased, cardiac arrest

, cerebral haemorrhage, convulsion, empyema, endocarditis

, septic embolus. Xigris dosage: unknown. During the same period patient was treated with LEVOPHED, DILANTIN, CEFTRIAXONE, DIFLUCAN, NAFICILLIN, FENTANYL CITRATE, PEPCID, ATROVENT. Patient was hospitalized. Patient died on 08/02/2005.

Xigris Side Effects Report #5389483-0
Xigris side effect was reported by a Physician from UNITED STATES on July 12, 2007. Female patient, 53 years of age, was diagnosed with sepsis

, prophylaxis and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemorrhage. Xigris dosage: unknown. During the same period patient was treated with HEPARIN. Patient died.

Xigris Side Effects Report #4599912-8
Xigris side effect was reported by a Physician from on Feb 11, 2005. Male patient, 53 years of age, weighting 143.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood calcium increased, blood sodium increased, brain oedema, brain scan abnormal, cerebral haemorrhage, haemoglobin decreased, international normalised ratio decreased. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOLE, CEFTRIAXONE, METRONIDAZOLE, CHLORAMPHENICOL, ALBUMIN NOS, HYDROCORTISONE, VITAMIN K, CAPTOPRIL. Patient was hospitalized and became disabled. Patient died.

Xigris Side Effects Report #4665001-7
Xigris side effect was reported by a Physician from on May 02, 2005. Male patient, 53 years of age, weighting 143.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood sodium increased, brain oedema, cerebral haemorrhage, haemoglobin decreased, intraventricular haemorrhage, platelet count increased, prothrombin time prolonged, white blood cell count increased. Xigris dosage: unknown. During the same period patient was treated with OMEPRAZOL, CEFTRIAXONE, METRONIDAZOLE, CHLORAMPHENICOL, TRAMADOL, ALBUMIN NOS, HYDROCORTISONE, VITAMIN K. Patient was hospitalized and became disabled. Patient died on 01/20/2005.

Xigris Side Effects Report #4815032-9
Xigris side effect was reported by a Health Professional from INDIA on Oct 07, 2005. Female patient, 52 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time, activated partial thromboplastin time prolonged, blood creatinine increased, cerebral haemorrhage, international normalised ratio increased, loss of consciousness, mydriasis, peritoneal dialysis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with SEDATIVE, MUSCLE RELAXANT, ANTIBIOTIC. Patient was hospitalized. Patient died on 09/28/2005.

Xigris Side Effects Report #4822100-4
Xigris side effect was reported by a Consumer or non-health professional from INDIA on Oct 14, 2005. Female patient, 52 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood creatine increased, cerebral haemorrhage, international normalised ratio increased, loss of consciousness, mydriasis, peritoneal dialysis, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with SEDATIVE, MUSCLE RELAXANT, ANTIBIOTIC. Patient was hospitalized. Patient died on 09/28/2005.

Xigris Side Effects Report #5206082-1
Xigris side effect was reported by a Physician from UNITED STATES on Jan 02, 2007. Female patient, 51 years of age, was diagnosed with sepsis

, infection

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with CIPROFLOXACIN, LEVOFLOXACIN, IMIPENEM, VANCOMYCIN HYDROCHLORIDE, CLINDAMYCIN, DIFLUCAN, FLAGYL. Patient recovered.

Xigris Side Effects Report #4822189-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Oct 14, 2005. Male patient, 51 years of age, weighting 169.8 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiac index increased, central venous pressure increased, culture stool positive, enterococcal infection, haematocrit decreased, haemoglobin decreased, haemorrhage intracranial, international normalised ratio decreased. Xigris dosage: unknown. During the same period patient was treated with ALPRAZOLAM, METRONIDAZOLE, FLUCONAZOLE, BICARBONATE, PANTOPRAZOLE, DOUBTAMINE, VASOPRESSINECTION, NOREPINEPHRINE. Patient recovered.

Xigris Side Effects Report #5017020-9
Xigris side effect was reported by a Physician from UNITED STATES on May 16, 2006. Male patient, 51 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased. Xigris dosage: unknown. During the same period patient was treated with HEPARIN. Patient recovered.

Xigris Side Effects Report #4686712-3
Xigris side effect was reported by a Consumer or non-health professional from on May 20, 2005. Male patient, 49 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, condition aggravated, haemorrhage intracranial, international normalised ratio increased, platelet count decreased, vessel puncture site haemorrhage. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN. Patient was hospitalized. Patient died on 03/29/2005.

Xigris Side Effects Report #5014373-2
Xigris side effect was reported by a Physician from NETHERLANDS on May 02, 2006. Male patient, 47 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, thrombocytopenia. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4741622-8
Xigris side effect was reported by a Physician from MEXICO on July 22, 2005. Female patient, 43 years of age, weighting 176.4 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiopulmonary failure, neurological symptom, prothrombin time prolonged, pulmonary haemorrhage. Xigris dosage: unknown. Patient was hospitalized. Patient died.

Xigris Side Effects Report #4800832-1
Xigris side effect was reported by a Physician from MEXICO on Sept 09, 2005. Female patient, 43 years of age, weighting 176.4 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiopulmonary failure, nervous system disorder, prothrombin time prolonged, pulmonary haemorrhage. Xigris dosage: unknown. Patient was hospitalized. Patient died.

Xigris Side Effects Report #5657504-3
Xigris side effect was reported by a Physician from UNITED STATES on Feb 27, 2008. Female patient, 42 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood glucose increased, diabetic ketoacidosis, international normalised ratio increased, liver function test abnormal, sepsis

. Xigris dosage: unknown. During the same period patient was treated with CYMBALTA, ANTIBIOTICS, NEOSYNEPHRINE, LEVOPHED. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5671149-0
Xigris side effect was reported by a Physician from UNITED STATES on Mar 05, 2008. Female patient, 42 years of age, was diagnosed with sepsis

, depression

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, diabetes mellitus, diabetic ketoacidosis, international normalised ratio increased, liver function test abnormal, sepsis

. Xigris dosage: unknown. During the same period patient was treated with CYMBALTA. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4752378-7
Xigris side effect was reported by a Physician from INDIA on Aug 08, 2005. Male patient, 40 years of age, weighting 154.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, brain oedema, haemorrhage intracranial, multi-organ failure, mydriasis, platelet count decreased, pupil fixed. Xigris dosage: unknown. During the same period patient was treated with ARTESUNATE, MEROPENEM, VANCOMYCIN, LASIX, NORADRENALINE, DOBUTAMINE, PANTOCID, FENTANYL. Patient died on 07/20/2005.

Xigris Side Effects Report #5179527-3
Xigris side effect was reported by a Physician from UNITED STATES on Oct 31, 2006. Female patient, 39 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, myocardial infarction, platelet count decreased. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS. Patient recovered.

Xigris Side Effects Report #5237516-4
Xigris side effect was reported by a Physician from UNITED KINGDOM on Feb 03, 2007. Female patient, 38 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, prothrombin time prolonged. Xigris dosage: 0.024 MG/KG, EVERY HOUR. Patient recovered.

Xigris Side Effects Report #4630497-3
Xigris side effect was reported by a Pharmacist from on Mar 19, 2005. Female patient, 37 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, haematuria, international normalised ratio increased, platelet count decreased. Xigris dosage: 34.3 MG/1 DAY. During the same period patient was treated with ANTITHROMBIN III. Patient recovered.

Xigris Side Effects Report #4698750-5
Xigris side effect was reported by a Physician from on June 08, 2005. Female patient, 36 years of age, weighting 132.3 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, epistaxis, haematuria. Xigris dosage: 34.3 MG/1 DAY. During the same period patient was treated with ANTITHROMBIN III. Patient recovered.

Xigris Side Effects Report #5660746-4
Xigris side effect was reported by a Physician from UNITED KINGDOM on Feb 27, 2008. Female patient, 34 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemorrhage, thrombocytopenia. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4949360-3
Xigris side effect was reported by a Physician from UNITED STATES on Feb 24, 2006. Female patient, 33 years of age, weighting 123.5 lb, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, condition aggravated, fibrin d dimer increased, fibrin degradation products increased, haemoglobin decreased, international normalised ratio increased, prothrombin time prolonged. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4824063-4
Xigris side effect was reported by a Physician from UNITED STATES on Oct 26, 2005. Female patient, 24 years of age, was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, life support, premature separation of placenta, prothrombin time prolonged, stillbirth. Xigris dosage: unknown. During the same period patient was treated with PHENYLEPHRINE, ATIVAN, VANCOMYCIN, GENTAMICIN, METHADONE, FENTANYL, ATROVENT, HEPARIN. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #5161955-3
Xigris side effect was reported by a Physician from UNITED STATES on Nov 22, 2006. Male patient was diagnosed with sepsis

, multi-organ failure and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, international normalised ratio decreased, respiratory tract haemorrhage, thrombosis. Xigris dosage: unknown. During the same period patient was treated with MERONEM, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, DORMICUM, GAMMAGARD, FUROSEMIDE. Patient recovered.

Xigris Side Effects Report #4955113-2
Xigris side effect was reported by a Pharmacist from UNITED STATES on Mar 09, 2006. Female patient was diagnosed with sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, laboratory test interference. Xigris dosage: unknown. Patient died.

Xigris Side Effects Report #4642958-1
Xigris side effect was reported by a Physician from on Apr 06, 2005. Female patient, 56 years of age, was diagnosed with pneumonia staphylococcal and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, intraventricular haemorrhage, ischaemia, limb injury, platelet count decreased, pupil fixed. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, ENOXAPARIN, FLOLAN. Patient recovered.

Xigris Side Effects Report #4614152-1
Xigris side effect was reported by a Physician from on Feb 28, 2005. Female patient, 50 years of age, was diagnosed with pneumonia staphylococcal and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, intraventricular haemorrhage, mydriasis, peripheral ischaemia, platelet count decreased, pupil fixed. Xigris dosage: unknown. During the same period patient was treated with HEPARIN, ENOXAPARIN, PROSTACYCLIN. Patient recovered.

Xigris Side Effects Report #4936378-X
Xigris side effect was reported by a Physician from UNITED STATES on Feb 16, 2006. Female patient was diagnosed with pneumonia

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood fibrinogen increased, coagulation test abnormal, condition aggravated, haematocrit decreased, haematuria, haemoglobin decreased, infusion related reaction, leukocytosis. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, LINEZOLID, MEROPENEM, CIPROFLOXACIN, VORICONAZOLE, FUROSEMIDE, MANNITOL. Patient recovered.

Xigris Side Effects Report #4564647-4
Xigris side effect was reported by a Physician from on Jan 11, 2005. Male patient, 69 years of age, weighting 165.3 lb, was diagnosed with multi-organ failure, sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood fibrinogen increased, coagulopathy, haematocrit decreased, haematuria, haemoglobin decreased, leukocytosis, petechiae, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with ENOXAPARIN, LINEZOLID, MEROPENEM, CIPROFLOXACIN, VORICONAZOLE, FUROSEMIDE, MANNITOL. Patient recovered.

Xigris Side Effects Report #4719083-4
Xigris side effect was reported by a Physician from POLAND on July 01, 2005. Male patient, 64 years of age, weighting 132.3 lb, was diagnosed with multi-organ failure, sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardiopulmonary failure, coagulopathy, gastrointestinal haemorrhage, international normalised ratio increased, respiratory tract haemorrhage. Xigris dosage: unknown. During the same period patient was treated with MERONMEN, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, MIDAZOLAM, GAMMAGARD. Patient died on 10/31/2004.

Xigris Side Effects Report #4608421-9
Xigris side effect was reported by a Physician from on Feb 22, 2005. Male patient, weighting 132.3 lb, was diagnosed with multi-organ failure, sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, respiratory tract haemorrhage. Xigris dosage: unknown. During the same period patient was treated with MERONEM, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, DORMICUM, GAMMAGARD. Patient recovered.

Xigris Side Effects Report #4648367-3
Xigris side effect was reported by a Physician from on Apr 13, 2005. Male patient, weighting 132.3 lb, was diagnosed with multi-organ failure, sepsis

and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, coagulopathy, international normalised ratio decreased, respiratory tract haemorrhage. Xigris dosage: unknown. During the same period patient was treated with MERONEM, LEVONOR, DOBUTREX, DOPAMINE, DOLARGAN, DORMICUM, GAMMARGARD. Patient recovered.

Xigris Side Effects Report #5051889-7
Xigris side effect was reported by a Health Professional from UNITED STATES on June 19, 2006. Male patient, 65 years of age, was diagnosed with disseminated intravascular coagulation and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, disseminated intravascular coagulation, gastrointestinal haemorrhage, platelet count decreased, sepsis

. Xigris dosage: unknown. Patient died on 06/01/2006.

Xigris Side Effects Report #4686773-1
Xigris side effect was reported by a Physician from on May 19, 2005. Female patient, 76 years of age, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, cardio-respiratory arrest, haemoglobin decreased, haemorrhage, international normalised ratio decreased, multi-organ failure, platelet count decreased. Xigris dosage: unknown. Patient died on 06/18/2004.

Xigris Side Effects Report #4630747-3
Xigris side effect was reported by a Pharmacist from on Mar 17, 2005. Female patient, 57 years of age, weighting 392.4 lb, was diagnosed with abdominal sepsis and was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, haemoglobin decreased, haemorrhage urinary tract, international normalised ratio increased, mouth haemorrhage, platelet count decreased, prothrombin time prolonged, septic shock. Xigris dosage: unknown. During the same period patient was treated with GENTAMICIN, ZOSYN, HEPARIN, AVELOX, TYLENOL, PHENYLEPHRINE, DOPAMINE, NOREPINEPHRINE. Patient died on 10/25/2004.

Xigris Side Effects Report #4648547-7
Xigris side effect was reported by a Pharmacist from on Apr 12, 2005. Female patient, 54 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, international normalised ratio increased, laboratory test abnormal. Xigris dosage: unknown. During the same period patient was treated with ANTIBIOTICS, HYDROCORTISONE, RANITIDINE, ADRENALINE, NORADRENALINE. Patient recovered.

Xigris Side Effects Report #4614077-1
Xigris side effect was reported by a Physician from on Feb 28, 2005. Male patient, 48 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, prothrombin time prolonged. Xigris dosage: unknown. During the same period patient was treated with ADRENALINE, NORADRENALINE. Patient died on 02/28/2005.

Xigris Side Effects Report #4746747-9
Xigris side effect was reported by a Physician from UNITED KINGDOM on July 30, 2005. Female patient, 38 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood fibrinogen decreased, haemodialysis, haemoglobin decreased, prothrombin time prolonged. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris Side Effects Report #4964474-X
Xigris side effect was reported by a Physician from GERMANY on Mar 20, 2006. Female patient, 38 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged. Xigris dosage: unknown. Patient died on 01/28/2006.

Xigris Side Effects Report #4987756-4
Xigris side effect was reported by a Physician from UNITED KINGDOM on Apr 10, 2006. Female patient, 23 years of age, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, puncture site haemorrhage, surgery

, thrombocytopenia. Xigris dosage: unknown. Patient recovered.

Xigris Side Effects Report #4824064-6
Xigris side effect was reported by a Physician from UNITED STATES on Oct 26, 2005. Male patient, weighting 1625 lb, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, blood pressure abnormal, life support, premature separation of placenta, prothrombin time prolonged, stillbirth. Xigris dosage: unknown. During the same period patient was treated with PHENYLEPHRINE, ATIVAN, NICOTINE, VANCOMYCIN, GENTAMICIN, METHADONE, FENTANYL, ATROVENT. Patient died on 07/19/2005.

Xigris Side Effects Report #4883137-2
Xigris side effect was reported by a Health Professional from UNITED STATES on Jan 17, 2006. Female patient, weighting 179.2 lb, was treated with Xigris. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, ear haemorrhage, epistaxis, pharyngeal haemorrhage, platelet count decreased. Xigris dosage: unknown. Patient was hospitalized. Patient recovered.

Xigris and activated partial thromboplastin time prolonged

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Xigris and activated partial thromboplastin time prolonged Patient Reports February 12, 2012

side effects of Xigris