Valproate and metabolic encephalopathy Patient Reports February 13, 2012

Valproate Side Effects Report #6136781-9
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 20, 2009. Male patient, child 5 years of age, was diagnosed with simple partial seizures and was treated with Valproate. After drug was administered, patient experienced the following side effects: hyperammonaemia, metabolic encephalopathy, mood altered. Valproate dosage: unknown. During the same period patient was treated with CARBAMAZEPINE, CLOBAZAM. Patient recovered.

Valproate Side Effects Report #6135611-9
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 20, 2009. Female patient, 26 years of age, was diagnosed with meningitis tuberculous, grand mal convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: hyperammonaemia, metabolic encephalopathy, mood altered. Valproate dosage: unknown. During the same period patient was treated with CLOBAZAM. Patient recovered.

Valproate Side Effects Report #5953682-7
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Nov 06, 2008. Female patient, 72 years of age, was diagnosed with mania, bipolar i disorder and was treated with Valproate. After drug was administered, patient experienced the following side effects: asterixis, asthenia, electroencephalogram abnormal, hyperammonaemia, hyperammonaemic encephalopathy, lethargy, metabolic encephalopathy, tremor. Valproate dosage: unknown. During the same period patient was treated with LAMOTRIGINE, CLOZAPINE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #6138155-3
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 23, 2009. Female patient, child 6 years of age, was diagnosed with lennox-gastaut syndrome and was treated with Valproate. After drug was administered, patient experienced the following side effects: confusional state, convulsion, hyperammonaemia, metabolic encephalopathy. Valproate dosage: unknown. During the same period patient was treated with CLONAZEPAM. Patient recovered.


Valproate Side Effects Report #6138345-X
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 23, 2009. Female patient, 17 years of age, was diagnosed with grand mal convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: convulsion, hyperammonaemia, metabolic encephalopathy, mood altered. Valproate dosage: unknown. During the same period patient was treated with CARBAMAZEPINE. Patient recovered.

Valproate Side Effects Report #4649731-9
Valproate side effect was reported by a Consumer or non-health professional from on Apr 15, 2005. Female patient, 55 years of age, was diagnosed with epilepsy  and was treated with Valproate. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, apathy, balance disorder, csf protein increased, cytolytic hepatitis, hypothermia , metabolic encephalopathy, neutropenia, social avoidant behaviour. Valproate dosage: unknown. During the same period patient was treated with HYDROCORTISONE, LEVOTHYROXINE, HEPTAMINOL HYDROCHLORIDE, ENDOTELON, ALLOPURINOL, PHENYTOIN, LEVETIRACETAM. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #4641335-7
Valproate side effect was reported by a Consumer or non-health professional from on Apr 06, 2005. Female patient, 55 years of age, was diagnosed with craniopharyngioma, epilepsy  and was treated with Valproate. After drug was administered, patient experienced the following side effects: activated partial thromboplastin time prolonged, apathy, balance disorder, cytolytic hepatitis, hypothermia , metabolic encephalopathy, neutropenia, social avoidant behaviour, somnolence. Valproate dosage: unknown. During the same period patient was treated with HYDROCORTISONE, LEVOTHYROXINE, HEPTAMINOL HYDROCHLORIDE, ENDOTELON, ALLOPURINOL. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5806357-9
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on July 03, 2008. Female patient, 71 years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: apraxia, asterixis, hyperammonaemia, metabolic encephalopathy. Valproate dosage: unknown. During the same period patient was treated with LAMOTRIGINE. Patient recovered.

Valproate Side Effects Report #6137284-8
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 23, 2009. Female patient, 30 years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: confusional state, hyperammonaemia, metabolic encephalopathy. Valproate dosage: unknown. Patient recovered.


Valproate Side Effects Report #6048736-3
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Jan 13, 2009. Female patient, 58 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hyperammonaemia, hyperammonaemic encephalopathy, metabolic encephalopathy. Valproate dosage: unknown. Patient recovered.

Valproate Side Effects Report #6073694-5
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Feb 02, 2009. Female patient, 58 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hyperammonaemia, hyperammonaemic encephalopathy, metabolic encephalopathy. Valproate dosage: 900-1200 MG. During the same period patient was treated with HENYTOIN, LACTULOSE. Patient recovered.

Valproate Side Effects Report #6093874-2
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Feb 18, 2009. Female patient, 58 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hyperammonaemia, hyperammonaemic encephalopathy, metabolic encephalopathy. Valproate dosage: 900-1200 MG. During the same period patient was treated with HENYTOIN, LACTULOSE. Patient recovered.

Valproate Side Effects Report #5006869-4
Valproate side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 01, 2005. Female patient, 57 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: hyperammonaemia, metabolic encephalopathy. Valproate dosage: 250 MG, 2 IN 1 D. During the same period patient was treated with ASPIRIN. Patient was hospitalized. Patient recovered.