Valproate and hyperammonaemia Patient Reports February 13, 2012

Valproate Side Effects Report #4899415-7
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 10, 1995. Female patient, 25 years of age, was diagnosed with suicide attempt, epilepsy  and was treated with Valproate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, coma, gamma-glutamyltransferase increased, hyperammonaemia, overdose, suicide attempt. Valproate dosage: unknown. During the same period patient was treated with VALPROATE CHRONO, PIMOZIDE, PHENOBARBITAL, CAFFEINE, CLOBAZAM. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #4901888-8
Valproate side effect was reported by a Consumer or non-health professional from on July 01, 1993. Male patient, 19 years of age, was diagnosed with suicide attempt and was treated with Valproate. After drug was administered, patient experienced the following side effects: brain oedema, coma, hyperammonaemia, intentional overdose, suicide attempt. Valproate dosage: unknown. During the same period patient was treated with FLUOXETINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #6136781-9
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 20, 2009. Male patient, child 5 years of age, was diagnosed with simple partial seizures and was treated with Valproate. After drug was administered, patient experienced the following side effects: hyperammonaemia, metabolic encephalopathy, mood altered. Valproate dosage: unknown. During the same period patient was treated with CARBAMAZEPINE, CLOBAZAM. Patient recovered.

Valproate Side Effects Report #5000215-8
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on May 02, 2006. Female patient, 36 years of age, was diagnosed with partial seizures, grand mal convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: anaemia, c-reactive protein increased, electroencephalogram abnormal, gamma-glutamyltransferase increased, hyperammonaemia, hypothermia . Valproate dosage: unknown. During the same period patient was treated with TOPIRAMATE, PHENOBARBITAL. Patient was hospitalized. Patient recovered.


Valproate Side Effects Report #5000568-0
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on May 02, 2006. Female patient, 36 years of age, was diagnosed with partial seizures, grand mal convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: anaemia, c-reactive protein increased, electroencephalogram abnormal, gamma-glutamyltransferase increased, hyperammonaemia, hypothermia . Valproate dosage: unknown. During the same period patient was treated with TOPIRAMATE, PHENOBARBITAL. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #6135611-9
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 20, 2009. Female patient, 26 years of age, was diagnosed with meningitis tuberculous, grand mal convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: hyperammonaemia, metabolic encephalopathy, mood altered. Valproate dosage: unknown. During the same period patient was treated with CLOBAZAM. Patient recovered.

Valproate Side Effects Report #5953682-7
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Nov 06, 2008. Female patient, 72 years of age, was diagnosed with mania, bipolar i disorder and was treated with Valproate. After drug was administered, patient experienced the following side effects: asterixis, asthenia, electroencephalogram abnormal, hyperammonaemia, hyperammonaemic encephalopathy, lethargy, metabolic encephalopathy, tremor. Valproate dosage: unknown. During the same period patient was treated with LAMOTRIGINE, CLOZAPINE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #6138155-3
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 23, 2009. Female patient, child 6 years of age, was diagnosed with lennox-gastaut syndrome and was treated with Valproate. After drug was administered, patient experienced the following side effects: confusional state, convulsion, hyperammonaemia, metabolic encephalopathy. Valproate dosage: unknown. During the same period patient was treated with CLONAZEPAM. Patient recovered.

Valproate Side Effects Report #6138345-X
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 23, 2009. Female patient, 17 years of age, was diagnosed with grand mal convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: convulsion, hyperammonaemia, metabolic encephalopathy, mood altered. Valproate dosage: unknown. During the same period patient was treated with CARBAMAZEPINE. Patient recovered.


Valproate Side Effects Report #6101178-4
Valproate side effect was reported by a Consumer or non-health professional from UNITED STATES on June 14, 2000. Male patient, child 2 years of age, weighting 28.66 lb, was diagnosed with epilepsy  and was treated with Valproate. After drug was administered, patient experienced the following side effects: hyperammonaemia. Valproate dosage: 120MG-500MG PER DAY. Patient recovered.

Valproate Side Effects Report #5806357-9
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on July 03, 2008. Female patient, 71 years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: apraxia, asterixis, hyperammonaemia, metabolic encephalopathy. Valproate dosage: unknown. During the same period patient was treated with LAMOTRIGINE. Patient recovered.

Valproate Side Effects Report #4703602-8
Valproate side effect was reported by a Consumer or non-health professional from on June 20, 2005. Female patient, child 5 years of age, weighting 44.09 lb, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: electroencephalogram abnormal, encephalopathy, hyperammonaemia. Valproate dosage: unknown. During the same period patient was treated with VALPROATE SYRUP, TOPIRAMATE, LAMOTRIGINE, CARBAMAZEPINE. Patient recovered.

Valproate Side Effects Report #6137284-8
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 23, 2009. Female patient, 30 years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: confusional state, hyperammonaemia, metabolic encephalopathy. Valproate dosage: unknown. Patient recovered.

Valproate Side Effects Report #5269242-X
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Mar 09, 2007. Male patient, 19 years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: encephalopathy, hyperammonaemia, status epilepticus, syncope. Valproate dosage: unknown. Patient was hospitalized. Patient recovered.


Valproate Side Effects Report #4660660-7
Valproate side effect was reported by a Consumer or non-health professional from on May 04, 2005. Male patient, 15 years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: convulsion, encephalopathy, hyperammonaemia. Valproate dosage: unknown. During the same period patient was treated with TOPIRAMATE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #4703607-7
Valproate side effect was reported by a Consumer or non-health professional from on June 20, 2005. Male patient, child 12 years of age, weighting 94.80 lb, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: encephalopathy, hyperammonaemia. Valproate dosage: unknown. During the same period patient was treated with TOPIRAMATE, CLONAZEPAM. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5418134-1
Valproate side effect was reported by a Consumer or non-health professional from TURKEY on Aug 07, 2007. Female patient, weighting 9.92 lb, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: brain oedema, hyperammonaemia, overdose. Valproate dosage: unknown. Patient died.

Valproate Side Effects Report #5130817-X
Valproate side effect was reported by a Pharmacist from UNITED STATES on Oct 17, 2006. Male patient, 47 years of age, weighting 266.8 lb, was diagnosed with bipolar disorder , schizophrenia and was treated with Valproate. After drug was administered, patient experienced the following side effects: confusional state, disorientation, hyperammonaemia. Valproate dosage: unknown. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #4687841-0
Valproate side effect was reported by a Consumer or non-health professional from on May 31, 2005. Male patient, 16 years of age, was diagnosed with automatism epileptic, headache  and was treated with Valproate. After drug was administered, patient experienced the following side effects: depersonalisation, depression , electroencephalogram abnormal, hyperammonaemia, obsessive-compulsive disorder , syncope. Valproate dosage: 300 TO APPROXIMATELY 900 MG. During the same period patient was treated with CARBAMAZEPINE. Patient was hospitalized. Patient recovered.


Valproate Side Effects Report #6048736-3
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Jan 13, 2009. Female patient, 58 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hyperammonaemia, hyperammonaemic encephalopathy, metabolic encephalopathy. Valproate dosage: unknown. Patient recovered.

Valproate Side Effects Report #6073694-5
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Feb 02, 2009. Female patient, 58 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hyperammonaemia, hyperammonaemic encephalopathy, metabolic encephalopathy. Valproate dosage: 900-1200 MG. During the same period patient was treated with HENYTOIN, LACTULOSE. Patient recovered.

Valproate Side Effects Report #6093874-2
Valproate side effect was reported by a Consumer or non-health professional from FRANCE on Feb 18, 2009. Female patient, 58 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hyperammonaemia, hyperammonaemic encephalopathy, metabolic encephalopathy. Valproate dosage: 900-1200 MG. During the same period patient was treated with HENYTOIN, LACTULOSE. Patient recovered.

Valproate Side Effects Report #5006869-4
Valproate side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 01, 2005. Female patient, 57 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: hyperammonaemia, metabolic encephalopathy. Valproate dosage: 250 MG, 2 IN 1 D. During the same period patient was treated with ASPIRIN. Patient was hospitalized. Patient recovered.