Valproate and hepatotoxicity Patient Reports February 13, 2012

Valproate Side Effects Report #5296682-5
Valproate side effect was reported by a Consumer or non-health professional from AUSTRALIA on Apr 06, 2007. Male patient, 19 years of age, was diagnosed with epilepsy , convulsion prophylaxis and was treated with Valproate. After drug was administered, patient experienced the following side effects: abnormal behaviour, hepatotoxicity, mouth injury, tooth injury. Valproate dosage: unknown. During the same period patient was treated with PHENYTOIN, CARBAMAZEPINE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5095544-6
Valproate side effect was reported by a Consumer or non-health professional from AUSTRALIA on Aug 22, 2006. Male patient, 19 years of age, was diagnosed with epilepsy , convulsion prophylaxis and was treated with Valproate. After drug was administered, patient experienced the following side effects: face injury, hepatotoxicity. Valproate dosage: unknown. During the same period patient was treated with PHENYTOIN, CARBAMAZEPINE, CLONAZEPAM. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5092179-6
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 8. years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: apathy, coma, convulsion, hepatotoxicity. Valproate dosage: unknown. During the same period patient was treated with SULTIAME. Patient died.

Valproate Side Effects Report #5092177-2
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Female patient, child 5 years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hepatotoxicity. Valproate dosage: unknown. During the same period patient was treated with PHENYTOIN. Patient was hospitalized. Patient recovered.


Valproate Side Effects Report #5092220-0
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 3. years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: convulsion, grand mal convulsion, hepatotoxicity, reye's syndrome, somnolence. Valproate dosage: unknown. During the same period patient was treated with ETHOSUXIMIDE, CLOBAZEPAM. Patient recovered.

Valproate Side Effects Report #5092216-9
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 2. years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: convulsion, hepatotoxicity, reye's syndrome, somnolence. Valproate dosage: unknown. Patient recovered.

Valproate Side Effects Report #5092217-0
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Female patient, child 2. years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: anorexia, apathy, coagulopathy, convulsion, hepatotoxicity, pancreatitis, reye's syndrome. Valproate dosage: unknown. During the same period patient was treated with ETHOSUXIMIDE. Patient recovered.

Valproate Side Effects Report #5092218-2
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 12 years of age, was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: anorexia, convulsion, hepatotoxicity, nausea . Valproate dosage: unknown. During the same period patient was treated with ETHOSUXIMIDE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #5092223-6
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient was diagnosed with convulsion and was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hepatotoxicity. Valproate dosage: unknown. During the same period patient was treated with PHENOBARBITAL. Patient recovered.


Valproate Side Effects Report #5685136-X
Valproate side effect was reported by a Consumer or non-health professional from TURKEY on Mar 18, 2008. Male patient, 38 years of age, was diagnosed with bipolar i disorder and was treated with Valproate. After drug was administered, patient experienced the following side effects: haematotoxicity, hepatotoxicity. Valproate dosage: unknown. During the same period patient was treated with OLANZAPINE. Patient was hospitalized. Patient recovered.

Valproate Side Effects Report #6101535-6
Valproate side effect was reported by a Physician from UNITED STATES on Nov 08, 2002. Female patient, child 6 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: hepatotoxicity. Valproate dosage: unknown. Patient recovered.

Valproate Side Effects Report #5092224-8
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Female patient, child 5 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, coordination abnormal, hepatotoxicity, lactic acidosis. Valproate dosage: unknown. During the same period patient was treated with PHENYTOIN. Patient died.

Valproate Side Effects Report #5092227-3
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Female patient, child 5 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hepatotoxicity, pneumonia . Valproate dosage: unknown. During the same period patient was treated with PHENYTOIN, LOBAZEPAM. Patient died.

Valproate Side Effects Report #5136467-3
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Female patient, child 5 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, coordination abnormal, grand mal convulsion, hepatic cirrhosis, hepatic steatosis, hepatocellular damage, hepatotoxicity, lactic acidosis. Valproate dosage: unknown. During the same period patient was treated with PHENYTOIN. Patient died.


Valproate Side Effects Report #4638668-7
Valproate side effect was reported by a Pharmacist from on Apr 15, 2005. Male patient, 25 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, bipolar disorder , hepatotoxicity. Valproate dosage: unknown. During the same period patient was treated with QUETIAPINE FUMARATE. Patient recovered.

Valproate Side Effects Report #5091640-8
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 2. years of age, was diagnosed with grand mal convulsion, lennox-gastaut syndrome and was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hepatotoxicity. Valproate dosage: unknown. Patient died.

Valproate Side Effects Report #5136475-2
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 2. years of age, was diagnosed with grand mal convulsion, lennox-gastaut syndrome and was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, grand mal convulsion, hepatic cirrhosis, hepatic steatosis, hepatocellular damage, hepatotoxicity, status epilepticus. Valproate dosage: unknown. Patient died.

Valproate Side Effects Report #5092226-1
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 11 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, disseminated intravascular coagulation, hepatotoxicity, thrombocytopenia. Valproate dosage: unknown. Patient died.

Valproate Side Effects Report #5092221-2
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 1 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, hepatic cirrhosis, hepatic steatosis, hepatotoxicity, infantile spasms. Valproate dosage: unknown. During the same period patient was treated with CORTICOTROPIN. Patient died.


Valproate Side Effects Report #5092222-4
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 1 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hepatic cirrhosis, hepatic steatosis, hepatotoxicity, infantile spasms. Valproate dosage: unknown. During the same period patient was treated with DEXAMETHASONE. Patient died.

Valproate Side Effects Report #5136464-8
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Male patient, child 1 years of age, was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, hepatic cirrhosis, hepatocellular damage, hepatotoxicity, infantile spasms. Valproate dosage: unknown. During the same period patient was treated with CORTICOTROPIN. Patient died.

Valproate Side Effects Report #5215954-3
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Jan 17, 2007. Female patient was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, hepatotoxicity, lactic acidosis. Valproate dosage: unknown. During the same period patient was treated with DIAZEPAM. Patient died.

Valproate Side Effects Report #5091639-1
Valproate side effect was reported by a Consumer or non-health professional from GERMANY on Aug 18, 2006. Female patient was treated with Valproate. After drug was administered, patient experienced the following side effects: coma, convulsion, grand mal convulsion, hepatic cirrhosis, hepatotoxicity, lactic acidosis, status epilepticus. Valproate dosage: unknown. During the same period patient was treated with DIAZEPAM. Patient died.

Valproate Side Effects Report #5676529-5
Valproate side effect was reported by a Health Professional from GERMANY on Mar 12, 2008. Female patient was treated with Valproate. After drug was administered, patient experienced the following side effects: hepatotoxicity. Valproate dosage: 50 MG/KG, QD. During the same period patient was treated with TOPIRAMATE. Patient recovered.