Trisenox and platelet count decreased Patient Reports February 13, 2012

Trisenox Side Effects Report #4855372-0
Trisenox side effect was reported by a Health Professional from UNITED STATES on Apr 05, 2005. Male patient, 70 years of age, weighting 175.0 lb, was diagnosed with myelodysplastic syndrome and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, av dissociation, fatigue, oedema peripheral, platelet count decreased, pyrexia, rash . Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4591872-9
Trisenox side effect was reported by a Physician from on Nov 02, 2004. Female patient, 66 years of age, was diagnosed with myelodysplastic syndrome and was treated with Trisenox. After drug was administered, patient experienced the following side effects: feeling abnormal, fluid retention, haematocrit decreased, oedema, platelet count decreased, retinoic acid syndrome, white blood cell count decreased. Trisenox dosage: 0.25 MG/KG (0.25 MG/KG, 5 DOSE LOAD), IVI. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4712479-6
Trisenox side effect was reported by a Consumer or non-health professional from UNITED STATES on June 20, 2005. Female patient, 70 years of age, weighting 126.0 lb, was diagnosed with multiple myeloma  and was treated with Trisenox. After drug was administered, patient experienced the following side effects: asthenia, cardiac failure congestive, dyspnoea, platelet count decreased, pyrexia, rash , white blood cell count decreased. Trisenox dosage: 14 MG IVI. During the same period patient was treated with MELPHALAN, ASCORBIC ACID, OXYTROL, SANTURA, FOLIC ACID. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4758899-5
Trisenox side effect was reported by a Physician from UNITED STATES on June 30, 2005. Female patient, 58 years of age, was diagnosed with multiple myeloma  and was treated with Trisenox. After drug was administered, patient experienced the following side effects: aphasia , platelet count decreased. Trisenox dosage: (0.25 MG/KG, 2X/WK), IVI. Patient was hospitalized. Patient recovered.


Trisenox Side Effects Report #5252018-7
Trisenox side effect was reported by a Physician from UNITED STATES on Feb 09, 2007. Male patient, 73 years of age, weighting 202.8 lb, was diagnosed with chronic myelomonocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: nephrolithiasis, platelet count decreased, renal failure. Trisenox dosage: 0.25 MG/KG QD DAYS 1-5, DAYS 8-12 INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, HYDREA. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5047197-0
Trisenox side effect was reported by a Physician from JAPAN on June 21, 2006. Female patient, 84 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: c-reactive protein increased, disseminated intravascular coagulation, haemoglobin decreased, hypokalaemia, malignant neoplasm progression, platelet count decreased, renal failure, respiratory failure. Trisenox dosage: 4.1 MG QD, INTRAVENOUS DRIP. During the same period patient was treated with FUROSEMIDE, MEXILETINE HYDROCHLORIDE, NIFEDIPINE, NIZATIDINE, INSULIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5022383-4
Trisenox side effect was reported by a Physician from JAPAN on May 30, 2006. Female patient, 84 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: c-reactive protein increased, hypokalaemia, platelet count decreased, white blood cell count decreased. Trisenox dosage: 4.1 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FUROSEMIDE, MEXILETINE HYDROCHLORIDE, NIFEDIPINE, NIZATIDINE, INSULIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5029162-2
Trisenox side effect was reported by a Physician from JAPAN on May 31, 2006. Female patient, 84 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia, c-reactive protein increased, haemoglobin decreased, hypokalaemia, malignant neoplasm progression, platelet count decreased, white blood cell count decreased. Trisenox dosage: 4.1 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FUROSEMIDE, MEXILETINE HYDROCHLORIDE, NIFEDIPINE, NIZATIDINE, INSULIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5361222-9
Trisenox side effect was reported by a Physician from JAPAN on June 04, 2007. Male patient, 73 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood pressure systolic decreased, bone marrow failure, c-reactive protein increased, haemoglobin decreased, neutrophil count decreased, platelet count decreased, pleural effusion, respiratory arrest, urine output decreased. Trisenox dosage: 9 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, ARBEKACIN SULPHATE, ARBEKACIN SULPHATE, ARBEKACIN SULPHATE, PREDNISOLONE SUCCINATE, NAFAMOSTAT, LENOGRASTIM. Patient died on 05/06/2007.


Trisenox Side Effects Report #4701597-4
Trisenox side effect was reported by a Physician from on June 07, 2005. Female patient, 73 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: erythema, hot flush, platelet count decreased, white blood cell count decreased. Trisenox dosage: 6.99 MG (6.99 MG, QD), IVI. During the same period patient was treated with SULFAMETHOXAZOLE, TRIMETHOPRIM, POLYMYXIN B SULPHATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5233587-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 23, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5248064-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 07, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5257757-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 15, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, protein total decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #4661118-1
Trisenox side effect was reported by a Physician from on Apr 26, 2005. Male patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: body temperature increased, disseminated intravascular coagulation, dyspnoea, electrocardiogram qt corrected interval prolonged, leukocytosis, platelet count decreased, ventricular tachycardia, white blood cell count decreased. Trisenox dosage: unknown. During the same period patient was treated with NAFAMOSTAT, MAGNESIUM SULPHATE. Patient recovered.


Trisenox Side Effects Report #5087025-0
Trisenox side effect was reported by a Physician from JAPAN on Aug 09, 2006. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, c-reactive protein increased, headache , hepatic function abnormal, platelet count decreased, rash , white blood cell count decreased. Trisenox dosage: 7.77 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #6088508-7
Trisenox side effect was reported by a Physician from JAPAN on Feb 09, 2009. Male patient, 46 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, haemoglobin decreased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.65 MG QD; INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, FILGRASTIM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #6108579-9
Trisenox side effect was reported by a Health Professional from JAPAN on Feb 19, 2009. Male patient, 46 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, haemoglobin decreased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.65 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, FILGRASTIM. Patient was hospitalized and became disabled. Patient recovered.

Trisenox Side Effects Report #6111418-3
Trisenox side effect was reported by a Physician from ITALY on Feb 25, 2009. Male patient, 45 years of age, weighting 264.6 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: cerebrovascular accident, platelet count decreased. Trisenox dosage: 15 MG INTRAVENOUS DRIP. During the same period patient was treated with ALL TRANS RETINOIC ACID. Patient recovered.

Trisenox Side Effects Report #4947900-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 23, 2006. Male patient, 33 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: platelet count decreased, white blood cell count decreased. Trisenox dosage: 10.8 MG QD INTRAVENOUS DRIP. During the same period patient was treated with HEPARIN, FAMOTIDINE, FLUCONAZOLE, SULFAMETHOXAZOLE, ACYCLOVIR. Patient was hospitalized. Patient recovered.


Trisenox Side Effects Report #4622031-9
Trisenox side effect was reported by a Physician from on Mar 08, 2005. Male patient, 78 years of age, was diagnosed with acute myeloid leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: aphasia , blood creatinine abnormal, coma, lung infiltration, platelet count decreased, pyrexia. Trisenox dosage: (0.25 MG/KG, 5 DOSE LOAD: 2X/WK), IVI. During the same period patient was treated with AMBIEN, CYTARABINE. Patient was hospitalized. Patient recovered.