Trisenox and pericardial effusion Patient Reports February 13, 2012

Trisenox Side Effects Report #5027342-3
Trisenox side effect was reported by a Physician from UNITED STATES on May 30, 2006. Female patient, 70 years of age, was diagnosed with myeloproliferative disorder and was treated with Trisenox. After drug was administered, patient experienced the following side effects: cardiac tamponade, pericardial effusion, pleural effusion, pneumonia . Trisenox dosage: 18 MG Q72HR INTRAVENOUS DRIP. During the same period patient was treated with THALIDOMIDE, DEXAMETHASONE, ASCORBIC ACID. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5041520-9
Trisenox side effect was reported by a Physician from UNITED STATES on June 14, 2006. Female patient, 70 years of age, was diagnosed with myeloproliferative disorder and was treated with Trisenox. After drug was administered, patient experienced the following side effects: cardiac tamponade, pericardial effusion, pleural effusion, pneumonia primary atypical, shoulder pain. Trisenox dosage: 18 MG Q72HR INTRAVENOUS DRIP. During the same period patient was treated with THALIDOMIDE, DEXAMETHASONE, ASCORBIC ACID. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4664229-X
Trisenox side effect was reported by a Physician from on May 04, 2005. Male patient, 75 years of age, weighting 156.1 lb, was diagnosed with multiple myeloma  and was treated with Trisenox. After drug was administered, patient experienced the following side effects: ascites, blood creatinine increased, blood urea increased, intestinal obstruction, nausea , pericardial effusion, pleural effusion. Trisenox dosage: 18 MG (18 MG, BIW), IVI. During the same period patient was treated with ASCORBIC ACID, THALOMID. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5371533-9
Trisenox side effect was reported by a Physician from UNITED STATES on June 15, 2007. Female patient, 55 years of age, weighting 213.8 lb, was diagnosed with multiple myeloma , neoplasm recurrence and was treated with Trisenox. After drug was administered, patient experienced the following side effects: atrial fibrillation , cardiotoxicity, disease progression, ejection fraction decreased, fall , fatigue, pain , pericardial effusion, pleural effusion. Trisenox dosage: 0.25 MG/KG DAYS 1-5 INTRAVENOUS DRIP. During the same period patient was treated with ASCORBIC ACID, BORTEZOMIB, ZYDONE. Patient was hospitalized. Patient recovered.


Trisenox Side Effects Report #5956013-1
Trisenox side effect was reported by a Health Professional from FRANCE on Nov 04, 2008. Male patient, 74 years of age, was diagnosed with acute promyelocytic leukaemia, acute myeloid leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: atelectasis, catheter related infection, interstitial lung disease, lung infiltration, pancytopenia, pericardial effusion, pulmonary embolism , sepsis , staphylococcal infection . Trisenox dosage: 12 MG DAYS 1-5 INTRAVENOUS. During the same period patient was treated with ZEVEDOS, GRANOCYTE, ONDANSETRON, SOLUPRED, VESANOID. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5979412-0
Trisenox side effect was reported by a Physician from FRANCE on Nov 07, 2008. Male patient, 74 years of age, was diagnosed with acute promyelocytic leukaemia, acute myeloid leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: catheter related infection, interstitial lung disease, pancytopenia, pericardial effusion, pulmonary embolism , sepsis . Trisenox dosage: 12 MG DAYS 1-5 INTRAVENOUS. During the same period patient was treated with ZAVEDOS, GRANOCYTE, ONDANSETRON, ROCEPHIN, OFLOCET, SOLUPRED. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5912530-1
Trisenox side effect was reported by a Physician from JAPAN on Aug 05, 2008. Male patient, 68 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt prolonged, pericardial effusion, pleural effusion, ventricular tachycardia. Trisenox dosage: 12.3 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, DAUNORUBICIN, LANATOSIDE C, HYDROCORTISONE SUCCINATE, FUROSEMIDE, ELECTROLYTE. Patient recovered.

Trisenox Side Effects Report #5959554-6
Trisenox side effect was reported by a Physician from JAPAN on Nov 06, 2008. Male patient, 68 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt prolonged, pericardial effusion, pleural effusion, ventricular tachycardia. Trisenox dosage: 12.3 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, DAUNORUBICIN, LANATOSIDE C, HYDROCORTISONE SUCCINATE, FUROSEMIDE, ELECTROLYTE, ELECTORLYTE. Patient recovered.

Trisenox Side Effects Report #5976516-3
Trisenox side effect was reported by a Physician from JAPAN on Nov 12, 2008. Male patient, 68 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt prolonged, pericardial effusion, pleural effusion, ventricular tachycardia. Trisenox dosage: 12.3 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, DAUNORUBICIN HYDROCHLORIDE, LANATOSIDE C, HYDROCORTISONE SUCCINATE, FUROSEMIDE, ELECTROLYTE. Patient recovered.


Trisenox Side Effects Report #6016196-4
Trisenox side effect was reported by a Health Professional from JAPAN on Nov 13, 2008. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, pericardial effusion, pseudomembranous colitis. Trisenox dosage: 4.75 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ANTITHROMBIN, INSULIN. Patient recovered.

Trisenox Side Effects Report #4743883-8
Trisenox side effect was reported by a Physician from JAPAN on July 20, 2005. Female patient, 36 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: pericardial effusion. Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4808174-5
Trisenox side effect was reported by a Physician from JAPAN on Sept 20, 2005. Female patient, 36 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: pericardial effusion. Trisenox dosage: unknown. During the same period patient was treated with SULFAMETHOXAZOLE, MEROPENEM. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #6088489-6
Trisenox side effect was reported by a Health Professional from JAPAN on Feb 09, 2009. Male patient, 25 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: chest pain , haemodynamic instability, pericardial effusion, pleural effusion. Trisenox dosage: 10 MG QD INTRAVENOUS DRIP. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #6108673-2
Trisenox side effect was reported by a Health Professional from JAPAN on Feb 23, 2009. Male patient, 25 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: cardiac tamponade, chest pain , haemoglobin decreased, hepatic enzyme increased, melaena, pericardial effusion, pleural effusion. Trisenox dosage: 10 MG QD INTRAVENOUS DRIP. During the same period patient was treated with PHENYTOIN, TOSUFLOXACIN TOSILATE, OXETHAZAINE, LANSOPRAZOLE, VALPROATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ALENDRONATE, BROTIZOLAM. Patient was hospitalized. Patient recovered.


Trisenox Side Effects Report #6141226-9
Trisenox side effect was reported by a Health Professional from JAPAN on Mar 19, 2009. Male patient, 25 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: cardiac tamponade, cardiovascular insufficiency, gastrointestinal haemorrhage, haemoglobin decreased, hepatic enzyme increased, pericardial effusion, pleural effusion. Trisenox dosage: 10 MG (10 MG, 1 IN 1 D), INTRAVENOUS DRIP. During the same period patient was treated with PHENYTOIN, TOSULFOXACIN TOSILATE, OXETHAZAINE, LANSOPRAZOLE, VALPROATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, ALENDRONATE HYDRATE, BROTIZOLAM. Patient was hospitalized. Patient recovered.