Trisenox and pancytopenia 
Trisenox and pancytopenia Patient Reports February 13, 2012
Trisenox Side Effects Report #5934904-5
Trisenox side effect was reported by a Physician from UNITED STATES on Oct 16, 2008. Male patient, 58 years of age, weighting 176.8 lb, was diagnosed with multiple myeloma
and was treated with Trisenox. After drug was administered, patient experienced the following side effects: autoimmune disorder, body temperature increased, chest discomfort, liver function test abnormal, pancytopenia, pericarditis, viral infection , wheezing, white blood cell count decreased. Trisenox dosage: unknown. During the same period patient was treated with ASCORBIC ACID, ASPIRIN, REGLAN. Patient was hospitalized. Patient recovered.Trisenox Side Effects Report #4615938-X
Trisenox side effect was reported by a Physician from on Feb 28, 2005. Female patient, 83 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: pancytopenia, ventricular extrasystoles. Trisenox dosage: 0.15 MG/KG, QD (5X/WK)), IVI. During the same period patient was treated with MEXILETINE. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #4644261-2
Trisenox side effect was reported by a Physician from on Feb 28, 2005. Female patient, 83 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: anaemia, pancytopenia, ventricular extrasystoles. Trisenox dosage: 0.15 MG/KG, QD. During the same period patient was treated with MEXILETINE. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #5608248-5
Trisenox side effect was reported by a Physician from JAPAN on Jan 11, 2008. Male patient, 80 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enterocolitis, hepatic function abnormal, pancytopenia, renal impairment. Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #5671610-9
Trisenox side effect was reported by a Physician from JAPAN on Feb 29, 2008. Male patient, 80 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enterocolitis, hepatic function abnormal, pancytopenia, renal impairment. Trisenox dosage: 8.25 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DISOPYRAMIDE PHOSPHATE, MEXILETINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #5015868-8
Trisenox side effect was reported by a Physician from JAPAN on May 17, 2006. Female patient, 75 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: pancytopenia. Trisenox dosage: 9.9 MG QD INTRAVENOUS DRIP. Patient recovered.
Trisenox Side Effects Report #5956013-1
Trisenox side effect was reported by a Health Professional from FRANCE on Nov 04, 2008. Male patient, 74 years of age, was diagnosed with acute promyelocytic leukaemia, acute myeloid leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: atelectasis, catheter related infection, interstitial lung disease, lung infiltration, pancytopenia, pericardial effusion, pulmonary embolism
, sepsis , staphylococcal infection . Trisenox dosage: 12 MG DAYS 1-5 INTRAVENOUS. During the same period patient was treated with ZEVEDOS, GRANOCYTE, ONDANSETRON, SOLUPRED, VESANOID. Patient was hospitalized. Patient recovered.Trisenox Side Effects Report #5979412-0
Trisenox side effect was reported by a Physician from FRANCE on Nov 07, 2008. Male patient, 74 years of age, was diagnosed with acute promyelocytic leukaemia, acute myeloid leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: catheter related infection, interstitial lung disease, pancytopenia, pericardial effusion, pulmonary embolism
, sepsis . Trisenox dosage: 12 MG DAYS 1-5 INTRAVENOUS. During the same period patient was treated with ZAVEDOS, GRANOCYTE, ONDANSETRON, ROCEPHIN, OFLOCET, SOLUPRED. Patient was hospitalized. Patient recovered.Trisenox Side Effects Report #5584462-2
Trisenox side effect was reported by a Physician from JAPAN on Dec 17, 2007. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, depressed level of consciousness, hepatic function abnormal, oral herpes, pancytopenia. Trisenox dosage: 8.4 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, PREDNISOLONE ACETATE, METHOTREXATE. Patient was hospitalized. Patient died on 12/02/2007.
Trisenox Side Effects Report #5589390-4
Trisenox side effect was reported by a Physician from JAPAN on Dec 26, 2007. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, depressed level of consciousness, gamma-glutamyltransferase increased, herpes simplex
, pancytopenia, respiratory failure, shock. Trisenox dosage: 8.4 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE. Patient was hospitalized. Patient died on 12/02/2007.Trisenox Side Effects Report #5746296-5
Trisenox side effect was reported by a Physician from JAPAN on May 08, 2008. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: decreased appetite, diarrhoea, nausea
, pancytopenia. Trisenox dosage: unknown. Patient recovered.Trisenox Side Effects Report #5856707-2
Trisenox side effect was reported by a Physician from JAPAN on Aug 12, 2008. Male patient, 70 years of age, weighting 158.7 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, decreased appetite, diarrhoea, electrocardiogram qt prolonged, nausea
, pancytopenia. Trisenox dosage: 10.627 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FLUCONAZOLE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, POLAPREZINC, BROTIZOLAM. Patient recovered.Trisenox Side Effects Report #4758956-3
Trisenox side effect was reported by a Health Professional from JAPAN on Aug 11, 2005. Male patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, pancytopenia. Trisenox dosage: 9.3 MG QD INTRAVENOUS DRIP. During the same period patient was treated with AMOXICILLIN AND CLAVULANATE POTASSIUM, ASCORBIC ACIDQ, CALCIUM PANTOTHENATE, DANAPAROID, GABEXATE MESILATE. Patient recovered.
Trisenox Side Effects Report #5301184-3
Trisenox side effect was reported by a Physician from JAPAN on Mar 26, 2007. Female patient, 59 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, pancytopenia. Trisenox dosage: 7.065 MG QD INTRAVENOUS DRIP. During the same period patient was treated with METHOTREXATE, PREDNISOLONE ACETATE. Patient recovered.
Trisenox Side Effects Report #6140196-7
Trisenox side effect was reported by a Health Professional from JAPAN on Mar 19, 2009. Male patient, 54 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: pancytopenia, stem cell transplant. Trisenox dosage: 0.15 MG/KG (0.15 MG/KG, 1 IN 1 D), INTRAVENOUS. Patient recovered.
Trisenox Side Effects Report #4701607-4
Trisenox side effect was reported by a Physician from on June 07, 2005. Female patient, 54 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood albumin decreased, blood alkaline phosphatase increased, blood urea decreased, electrocardiogram qt prolonged, hyperglycaemia, pancytopenia, protein total decreased. Trisenox dosage: 5.67 MG (5.67 MG, QD), IVI. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #5320868-4
Trisenox side effect was reported by a Physician from JAPAN on Apr 24, 2007. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, ascites, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, neuropathy peripheral, pancytopenia, pleural effusion, respiratory failure, weight increased. Trisenox dosage: 8.25 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, FUROSEMIDE, DANAPAROID. Patient recovered.
Trisenox Side Effects Report #5635741-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 05, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia, convulsion prophylaxis and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blister, convulsion, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, meningitis
, pancytopenia, pseudomonas infection. Trisenox dosage: 10.425 MG,QD,INTRAVENOUS DRIP. During the same period patient was treated with VALPROATE, CYTARABINE, METHOTREXATE, PREDNISOLONE ACETATE, NAFAMOSTATE. Patient was hospitalized. Patient recovered.Trisenox Side Effects Report #5643136-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 13, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia, convulsion prophylaxis and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, catheter site infection, central nervous system leukaemia, electrocardiogram qt prolonged, hepatic function abnormal, herpes zoster, meningitis
, pancytopenia, pseudomonas infection. Trisenox dosage: 10.425 MG QD INTRAVENOUS DRIP. During the same period patient was treated with VALPROATE, CYTARABINE, METHOTREXATE, PREDNISOLONE ACETATE, NAFAMOSTATE. Patient was hospitalized. Patient recovered.Trisenox Side Effects Report #5701451-5
Trisenox side effect was reported by a Health Professional from JAPAN on Mar 24, 2008. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt prolonged, hepatic function abnormal, pancytopenia. Trisenox dosage: 10.095 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, PREDNISOLONE. Patient recovered.
Trisenox Side Effects Report #5413103-X
Trisenox side effect was reported by a Consumer or non-health professional from JAPAN on July 09, 2007. Female patient, 51 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, pancytopenia. Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #6140101-3
Trisenox side effect was reported by a Consumer or non-health professional from JAPAN on Mar 19, 2009. Male patient, 40 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood product transfusion dependent, bone marrow failure, pancytopenia, stem cell transplant. Trisenox dosage: (0.15 MG/KG), INTRAVENOUS; 2 COURSES (ACCUMULATED DOSE, 950 MG TOTAL DOSE), INTRAVENOUS. Patient recovered.
Trisenox Side Effects Report #5281885-6
Trisenox side effect was reported by a Physician from JAPAN on Mar 12, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hypokalaemia, pancytopenia. Trisenox dosage: 8.85 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CEFDINIR, ETIZOLAM, FEXOFENADINE HYDROCHLORIDE, RANITIDINE HYDROCHLORIDE, ZOLPIDEM TARTRATE, GEFARNATE. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #5397292-1
Trisenox side effect was reported by a Physician from JAPAN on July 05, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, c-reactive protein increased, electrocardiogram qt prolonged, hepatic function abnormal, hypocalcaemia, pancytopenia. Trisenox dosage: 9.15 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FEXOFENADINE HYDROCHLORIDE, RANITIDINE HYDROCHLORIDE, GEFARNATE, ETIZOLAM, ZOLPIDEM TARTRATE. Patient recovered.
Trisenox Side Effects Report #6039384-X
Trisenox side effect was reported by a Physician from UNITED KINGDOM on Jan 06, 2009. Male patient, 76 years of age, was diagnosed with acute myeloid leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: pancytopenia. Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.
Trisenox Side Effects Report #5574047-6
Trisenox side effect was reported by a Physician from JAPAN on Dec 12, 2007. Male patient, 70 years of age, was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, dry mouth, herpes simplex
, oral intake reduced, pancytopenia. Trisenox dosage: unknown. Patient died on 11/25/2007.Trisenox Side Effects Report #5278708-8
Trisenox side effect was reported by a Physician from JAPAN on Mar 05, 2007. Male patient, 53 years of age, was treated with Trisenox. After drug was administered, patient experienced the following side effects: pancytopenia, respiratory failure. Trisenox dosage: unknown. Patient recovered.
Trisenox Side Effects Report #5588255-1
Trisenox side effect was reported by a Physician from JAPAN on Dec 26, 2007. Female patient was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, enteritis, hepatic function abnormal, pancytopenia. Trisenox dosage: unknown. Patient recovered.