Trisenox and gamma-glutamyltransferase increased Patient Reports February 13, 2012

Trisenox Side Effects Report #5536194-4
Trisenox side effect was reported by a Physician from JAPAN on Nov 20, 2007. Male patient, 88 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood alkaline phosphatase increased, c-reactive protein increased, electrocardiogram qt prolonged, fluid retention, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 7.05 MG QD INTRAVENOUS DRIP. During the same period patient was treated with SULFAMETHOXAZOLE AND TRIMETHOPRIM, POLYMYXIN B SULPHATE. Patient recovered.

Trisenox Side Effects Report #6073095-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 28, 2009. Male patient, 85 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, blood lactate dehydrogenase increased, diarrhoea, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hyperglycaemia, leukocytosis, leukopenia. Trisenox dosage: 8.4 MG DAILY INTRAVENOUS. During the same period patient was treated with GABEXATE MESILATE. Patient recovered.

Trisenox Side Effects Report #5309186-8
Trisenox side effect was reported by a Physician from JAPAN on Apr 09, 2007. Female patient, 77 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood lactate dehydrogenase increased, electrocardiogram qt prolonged, fibrin d dimer increased, gamma-glutamyltransferase increased, protein total decreased, white blood cell count decreased. Trisenox dosage: 9.315 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FAMOTIDINE, SIMVASTATIN. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5081599-1
Trisenox side effect was reported by a Physician from JAPAN on July 27, 2006. Female patient, 77 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood albumin decreased, blood lactate dehydrogenase increased, c-reactive protein increased, electrocardiogram qt prolonged, fibrin d dimer increased, gamma-glutamyltransferase increased, protein total decreased. Trisenox dosage: 9.315 MG QD INTRAVENOUS DRIP. Patient recovered.


Trisenox Side Effects Report #4609439-2
Trisenox side effect was reported by a Physician from on Feb 21, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #4618289-2
Trisenox side effect was reported by a Physician from on Mar 02, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #4675632-6
Trisenox side effect was reported by a Physician from on Feb 14, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 4.8 MG (4.8 MG,), INTRAVENOUS. Patient recovered.

Trisenox Side Effects Report #4686792-5
Trisenox side effect was reported by a Physician from on May 08, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal. Trisenox dosage: 4.8 MG (4.8 MG) INTRAVENOUS. Patient recovered.

Trisenox Side Effects Report #4781090-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 07, 2005. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6 MG (6 MG, IVI). During the same period patient was treated with BIAPENEM, VANCOMYCIN, CLINDAMYCIN, CEFTAZIDIME, ALLOPURINOL, TOSUFOXACIN, FLUCONAZOLE, FAMOTIDINE. Patient recovered.


Trisenox Side Effects Report #4950882-X
Trisenox side effect was reported by a Physician from JAPAN on Mar 01, 2006. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6.6 MG QD INTRAVENOUS DRIP. During the same period patient was treated with BIAPENEM, TOSUFLOXACIN TOSILATE, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #5589390-4
Trisenox side effect was reported by a Physician from JAPAN on Dec 26, 2007. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, depressed level of consciousness, gamma-glutamyltransferase increased, herpes simplex , pancytopenia, respiratory failure, shock. Trisenox dosage: 8.4 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE. Patient was hospitalized. Patient died on 12/02/2007.

Trisenox Side Effects Report #5872002-X
Trisenox side effect was reported by a Physician from JAPAN on Aug 19, 2008. Male patient, 70 years of age, weighting 158.7 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, decreased appetite, diarrhoea, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, nausea , pancytopenia. Trisenox dosage: 10.627 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FLUCONAZOLE, SULFAMETHOXAZOLE AND TRIMETHOPRIM, POLAPREZINC, BROTIZOLAM, FOSFLUCONAZOLE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5233587-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 23, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5248064-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 07, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, white blood cell count decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.


Trisenox Side Effects Report #5248065-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 06, 2007. Male patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, catheter related infection, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hyperglycaemia, pathogen resistance, staphylococcal infection . Trisenox dosage: 9.69 MG Q1D INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, METHYLPHENIDATE, ALPRAZOLAM, MILNACIPRAN HYDROCHLORIDE, AMIKACIN SULPHATE, PAROXETINE HYDROCHLORIDE. Patient recovered.

Trisenox Side Effects Report #5257757-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 15, 2007. Female patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, febrile neutropenia, gamma-glutamyltransferase increased, hepatic function abnormal, platelet count decreased, protein total decreased. Trisenox dosage: 7.95 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5306139-0
Trisenox side effect was reported by a Physician from JAPAN on Apr 02, 2007. Male patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, cardio-respiratory arrest, electrocardiogram qt prolonged, febrile neutropenia, gamma-glutamyltransferase increased, hyperglycaemia, staphylococcal sepsis. Trisenox dosage: 9.69 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, QUETIAPINE FUMARATE, VANCOMYCIN HYDROCHLORIDE, CEFEPIME DIHYDROCHLORIDE, METHYLPHENIDATE, PAROXETINE. Patient died on 01/19/2006.

Trisenox Side Effects Report #5390810-9
Trisenox side effect was reported by a Physician from JAPAN on July 06, 2007. Male patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, catheter related infection, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hyperglycaemia, staphylococcal infection . Trisenox dosage: 9.69 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, METHYLPHENIDATE, ALPRAZOLAM, MILNACIPRAN HYDROCHLORIDE, AMIKACIN SULPHATE, PAROXETINE HYDROCHLORIDE HYDRATE. Patient recovered.

Trisenox Side Effects Report #5393083-6
Trisenox side effect was reported by a Physician from JAPAN on June 27, 2007. Male patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood lactate dehydrogenase increased, cardio-respiratory arrest, electrocardiogram qt prolonged, febrile neutropenia, gamma-glutamyltransferase increased, hyperglycaemia, staphylococcal sepsis. Trisenox dosage: 9.69 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, QUETIAPINE FUMARATE, VANCOMYCIN HYDROCHLORIDE, CEFEPIME DIHYDROCHLORIDE, METHYLPHENIDATE, PAROXETINE HYDROCHLORIDE HYDRATE. Patient died on 01/19/2006.


Trisenox Side Effects Report #6016196-4
Trisenox side effect was reported by a Health Professional from JAPAN on Nov 13, 2008. Female patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, gamma-glutamyltransferase increased, hepatic function abnormal, pericardial effusion, pseudomembranous colitis. Trisenox dosage: 4.75 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ANTITHROMBIN, INSULIN. Patient recovered.

Trisenox Side Effects Report #5047198-2
Trisenox side effect was reported by a Physician from JAPAN on June 23, 2006. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased. Trisenox dosage: 8.76 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, IDARUBICIN, MEXILETINE HYDROCHLORIDE, GABEXATE MESILATE, AMIKACIN SULPHATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4938437-4
Trisenox side effect was reported by a Physician from JAPAN on Feb 21, 2006. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.76 MG QD INTRAVENOUS. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, CYTARABINE, GABEXATE MESILATE, AMIKACIN SULPHATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5220983-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 09, 2007. Female patient, 62 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, leukocytosis. Trisenox dosage: 8.19 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN HDYROCHLORIDE, CYTARABINE, DANAPAROID. Patient recovered.

Trisenox Side Effects Report #5175209-2
Trisenox side effect was reported by a Physician from JAPAN on Nov 22, 2006. Female patient, 62 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: gamma-glutamyltransferase increased. Trisenox dosage: 8.19 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DANAPAROID, IDARUBICIN, CYTARABINE. Patient recovered.


Trisenox Side Effects Report #5706352-4
Trisenox side effect was reported by a Physician from JAPAN on Mar 31, 2008. Female patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.175 MG QD INTRAVENOUS DRIP. During the same period patient was treated with POLYMYXIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient recovered.

Trisenox Side Effects Report #5724215-5
Trisenox side effect was reported by a Physician from JAPAN on Apr 14, 2008. Female patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.175 MG, QD; INTRAVENOUS DRIP. During the same period patient was treated with POLYMYXIN B SULPHATE, SULFAMETHOXAZOLE AND TRIMETHOPRIM. Patient recovered.

Trisenox Side Effects Report #5320869-6
Trisenox side effect was reported by a Physician from JAPAN on Apr 23, 2007. Male patient, 50 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, csf test abnormal, cytology abnormal, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 9.48 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #5933636-7
Trisenox side effect was reported by a Physician from JAPAN on Oct 16, 2008. Male patient, 42 years of age, weighting 133.8 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, cardiomegaly, gamma-glutamyltransferase increased, hyperglycaemia, hyperuricaemia, hypoalbuminaemia. Trisenox dosage: 8.7 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DEXAMETHASONE PHOSPHATE, DEXAMETHASONE PHOSPHATE, DEXAMETHASONE PHOSPHATE, IDARUBICIN HYDROCHLORIDE, LANSOPRAZOLE, ITRACONAZOLE. Patient recovered.

Trisenox Side Effects Report #5486001-3
Trisenox side effect was reported by a Physician from JAPAN on Oct 01, 2007. Female patient, 38 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, gamma-glutamyltransferase increased, oedema, weight increased. Trisenox dosage: unknown. Patient recovered.


Trisenox Side Effects Report #5556932-4
Trisenox side effect was reported by a Physician from JAPAN on Nov 26, 2007. Female patient, 38 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase decreased, blood magnesium decreased, blood potassium decreased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash . Trisenox dosage: 8.55 MG QD; INTRAVENOUS DRIP. During the same period patient was treated with GLYCYRRHIZIN, MAGNESIUM REPLACEMENT, POTASSIUM REPLACEMENT, HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.

Trisenox Side Effects Report #5635799-X
Trisenox side effect was reported by a Physician from JAPAN on Feb 07, 2008. Female patient, 38 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood magnesium decreased, blood potassium decreased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash . Trisenox dosage: 8.55 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GLYCYRRHIZIN, MAGNESIUM REPLACEMENT, POTASSIUM REPLACEMENT, HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.

Trisenox Side Effects Report #5301086-2
Trisenox side effect was reported by a Physician from JAPAN on Mar 26, 2007. Female patient, 37 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: accelerated idioventricular rhythm, alanine aminotransferase increased, alopecia, aspartate aminotransferase increased, c-reactive protein increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased, leukocytosis, nausea . Trisenox dosage: 8.978 MG QD INTRAVENOUS DRIP. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, GRANISETRN HYDROCHLORIDE. Patient recovered.

Trisenox Side Effects Report #5574034-8
Trisenox side effect was reported by a Physician from JAPAN on Dec 14, 2007. Male patient, 28 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, haemoglobin decreased, tonsillitis. Trisenox dosage: 12 MG QD; INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, FLUCONAZOLE, OMEPRAZOLE, ROXATIDINE ACETATE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #5580740-1
Trisenox side effect was reported by a Physician from JAPAN on Dec 06, 2007. Male patient, 28 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase increased, c-reactive protein increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal, tonsillitis. Trisenox dosage: 12 MG QD INTRAVENOUS DRIP. During the same period patient was treated with DALTEPARIN, SULFAMETHOXAZOLE AND TRIMETHOPRIM, FLUCONAZOLE, OMEPRAZOLE, ROXATIDINE ACETATE, FAMOTIDINE. Patient was hospitalized. Patient recovered.


Trisenox Side Effects Report #5507315-4
Trisenox side effect was reported by a Physician from JAPAN on Oct 22, 2007. Female patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt prolonged, gamma-glutamyltransferase increased, hepatic function abnormal, oedema, rash , weight increased. Trisenox dosage: 8.55 MG QD INTRAVENOUS DRIP. During the same period patient was treated with HYDROCORTISONE SUCCINATE, PREDNISOLONE, SPIRONOLACTONE, FUROSEMIDE. Patient recovered.