Trisenox and electrocardiogram qt corrected interval prolonged Patient Reports February 13, 2012

Trisenox Side Effects Report #5354590-5
Trisenox side effect was reported by a Physician from JAPAN on June 04, 2007. Male patient, 73 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: altered state of consciousness, brain stem infarction, dysphagia, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, haemodialysis. Trisenox dosage: 10.05 MG QD, INTRAVENOUS DRIP. During the same period patient was treated with TRETINOIN, GABEXATE MESILATE, DALTEPARIN, CALCIUM GLUCONATE. Patient recovered.

Trisenox Side Effects Report #5201251-9
Trisenox side effect was reported by a Physician from JAPAN on Dec 20, 2006. Male patient, 70 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, ventricular extrasystoles, ventricular tachycardia. Trisenox dosage: 77.8 MG QD INTRAVENOUS DRIP. During the same period patient was treated with TRETINOIN, HYDROXYCARBAMIDE, NAFAMOSTAT MESILATE, CEFMETAZOLE, SPIRONOLACTONE. Patient recovered.

Trisenox Side Effects Report #4712344-4
Trisenox side effect was reported by a Physician from JAPAN on June 20, 2005. Male patient, 67 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, chest x-ray abnormal, dyspnoea exacerbated, electrocardiogram qt corrected interval prolonged, lung injury, ventricular extrasystoles, white blood cell count increased. Trisenox dosage: 8 MG (8 MG,), IVI. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4661118-1
Trisenox side effect was reported by a Physician from on Apr 26, 2005. Male patient, 66 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: body temperature increased, disseminated intravascular coagulation, dyspnoea, electrocardiogram qt corrected interval prolonged, leukocytosis, platelet count decreased, ventricular tachycardia, white blood cell count decreased. Trisenox dosage: unknown. During the same period patient was treated with NAFAMOSTAT, MAGNESIUM SULPHATE. Patient recovered.


Trisenox Side Effects Report #4831873-6
Trisenox side effect was reported by a Physician from JAPAN on Nov 01, 2005. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged. Trisenox dosage: 8.76 MG QD INTRAVENOUS. During the same period patient was treated with MEXILETINE HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4938437-4
Trisenox side effect was reported by a Physician from JAPAN on Feb 21, 2006. Male patient, 64 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: 8.76 MG QD INTRAVENOUS. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, CYTARABINE, GABEXATE MESILATE, AMIKACIN SULPHATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4716462-6
Trisenox side effect was reported by a Physician from JAPAN on July 05, 2005. Male patient, 63 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: depressed level of consciousness, disseminated intravascular coagulation, electrocardiogram qt corrected interval prolonged, hypocalcaemia, hyponatraemia, leukocytosis, nervous system disorder, restlessness. Trisenox dosage: unknown. During the same period patient was treated with DAUNORUBICIN HYDROCHLORIDE, ITRACONAZOLE, SULFAMETHOXAZOLE, DALTEPARIN, METHOTREXATE, CYTARABINE, DEXAMETHASONE PHOSPHATE. Patient recovered.

Trisenox Side Effects Report #4732834-8
Trisenox side effect was reported by a Physician from JAPAN on July 12, 2005. Male patient, 63 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: central nervous system lesion, condition aggravated, depressed level of consciousness, disseminated intravascular coagulation, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hypocalcaemia, hyponatraemia, leukocytosis. Trisenox dosage: unknown. During the same period patient was treated with DAUNORUBICIN HYDROCHLORIDE, ITRACONAZOLE, SULFAMETHOXAZOLE, DALTEPARIN, METHOTREXATE, CYTARABINE. Patient recovered.

Trisenox Side Effects Report #5136828-2
Trisenox side effect was reported by a Physician from JAPAN on Oct 05, 2006. Female patient, 62 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hepatic function abnormal, white blood cell count decreased. Trisenox dosage: 6.975 MG QD INTRAVENOUS DRIP. Patient recovered.


Trisenox Side Effects Report #4758956-3
Trisenox side effect was reported by a Health Professional from JAPAN on Aug 11, 2005. Male patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, pancytopenia. Trisenox dosage: 9.3 MG QD INTRAVENOUS DRIP. During the same period patient was treated with AMOXICILLIN AND CLAVULANATE POTASSIUM, ASCORBIC ACIDQ, CALCIUM PANTOTHENATE, DANAPAROID, GABEXATE MESILATE. Patient recovered.

Trisenox Side Effects Report #5301184-3
Trisenox side effect was reported by a Physician from JAPAN on Mar 26, 2007. Female patient, 59 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, pancytopenia. Trisenox dosage: 7.065 MG QD INTRAVENOUS DRIP. During the same period patient was treated with METHOTREXATE, PREDNISOLONE ACETATE. Patient recovered.

Trisenox Side Effects Report #5320868-4
Trisenox side effect was reported by a Physician from JAPAN on Apr 24, 2007. Male patient, 53 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, ascites, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, neuropathy peripheral, pancytopenia, pleural effusion, respiratory failure, weight increased. Trisenox dosage: 8.25 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, FUROSEMIDE, DANAPAROID. Patient recovered.

Trisenox Side Effects Report #4638293-8
Trisenox side effect was reported by a Physician from on Mar 14, 2005. Female patient, 52 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: basophilia, electrocardiogram qt corrected interval prolonged, leukocytosis, pyrexia. Trisenox dosage: unknown. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4848006-2
Trisenox side effect was reported by a Physician from JAPAN on Aug 24, 2005. Female patient, 52 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: basophilia, electrocardiogram qt corrected interval prolonged, leukocytosis, pyrexia. Trisenox dosage: 9.52 MG QD INTRAVENOUS DRIP. During the same period patient was treated with INSULIN, SPIRONOLACTONE, LANSOPRAZOLE, LEVOFLOXACIN, TAZOBACTAM, VANCOMYCIN HYDROCHLORIDE. Patient was hospitalized. Patient recovered.


Trisenox Side Effects Report #5114873-0
Trisenox side effect was reported by a Physician from JAPAN on Sept 05, 2006. Female patient, 43 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hepatic function abnormal, white blood cell count decreased. Trisenox dosage: 8.19 MG QD INTRAVENOUS DRIP. During the same period patient was treated with POTASSIUM CHLORIDE, TEPRENONE, MAGNESIUM OXIDE. Patient recovered.

Trisenox Side Effects Report #4801568-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 29, 2005. Female patient, 41 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, ventricular extrasystoles. Trisenox dosage: 8.7 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #4806740-4
Trisenox side effect was reported by a Physician from JAPAN on Oct 12, 2005. Female patient, 41 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, ventricular extrasystoles. Trisenox dosage: 8.7 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #5102981-X
Trisenox side effect was reported by a Physician from JAPAN on Aug 23, 2006. Male patient, 39 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, hypernatraemia, hypokalaemia, white blood cell count decreased. Trisenox dosage: 10.98 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CYTARABINE, METHOTREXATE, DEXAMETHASONE PHOSPHATE, ELECTROLYTE SOLUTION, RANITIDINE HYDROCHLORIDE. Patient recovered.

Trisenox Side Effects Report #5301086-2
Trisenox side effect was reported by a Physician from JAPAN on Mar 26, 2007. Female patient, 37 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: accelerated idioventricular rhythm, alanine aminotransferase increased, alopecia, aspartate aminotransferase increased, c-reactive protein increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased, leukocytosis, nausea . Trisenox dosage: 8.978 MG QD INTRAVENOUS DRIP. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, GRANISETRN HYDROCHLORIDE. Patient recovered.


Trisenox Side Effects Report #5175210-9
Trisenox side effect was reported by a Physician from JAPAN on Nov 22, 2006. Female patient, 37 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: accelerated idioventricular rhythm, acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, alopecia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, c-reactive protein increased, electrocardiogram qt corrected interval prolonged, gamma-glutamyltransferase increased. Trisenox dosage: 8.978 MG QD INTRAVENOUS DRIP. During the same period patient was treated with MEXILETINE HYDROCHLORIDE, GRANISETRON. Patient recovered.

Trisenox Side Effects Report #4801211-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 26, 2005. Female patient, 36 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: bacterial infection , blood bilirubin increased, c-reactive protein increased, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, jaundice , neutrophil count decreased, pyrexia, white blood cell count decreased. Trisenox dosage: 6.93 MG QD INTRAVENOUS DRIP. During the same period patient was treated with LACTOBACILLUS CASEI, LENOGRASTIM, CEFCAPENE PIVOXIL, GENTAMICIN, BUFEXAMAC. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5260932-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 20, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase decreased, blood urea decreased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, protein total decreased, rash , white blood cell count decreased. Trisenox dosage: 7.05 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ELECTROLYTE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5281885-6
Trisenox side effect was reported by a Physician from JAPAN on Mar 12, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hypokalaemia, pancytopenia. Trisenox dosage: 8.85 MG QD INTRAVENOUS DRIP. During the same period patient was treated with CEFDINIR, ETIZOLAM, FEXOFENADINE HYDROCHLORIDE, RANITIDINE HYDROCHLORIDE, ZOLPIDEM TARTRATE, GEFARNATE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5368842-6
Trisenox side effect was reported by a Physician from JAPAN on June 13, 2007. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, anaemia, aspartate aminotransferase increased, c-reactive protein increased, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hepatic function abnormal, hypocalcaemia, leukopenia. Trisenox dosage: 9.15 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FEXOFENADINE HYDROCHLORIDE, RANITIDINE HYDROCHLORIDE, GEFARNATE, ETIZOLAM, ZOLPIDEM TARTRATE. Patient recovered.


Trisenox Side Effects Report #5164850-9
Trisenox side effect was reported by a Physician from JAPAN on Nov 14, 2006. Female patient, 32 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood lactate dehydrogenase decreased, electrocardiogram qt corrected interval prolonged, hepatic function abnormal, protein total decreased, rash , white blood cell count decreased. Trisenox dosage: 7.05 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ELECTROLYTE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #4837395-0
Trisenox side effect was reported by a Physician from JAPAN on Nov 08, 2005. Male patient, 24 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: delirium, depressed level of consciousness, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hypoaesthesia. Trisenox dosage: 0.15 MG QD INTRAVENOUS DRIP. During the same period patient was treated with VANCOMYCIN HYDROCHLORIDE, MICAFUNGIN, BIAPENEM, AMIKACIN SULPHATE, MIRIMOSTIM. Patient recovered.

Trisenox Side Effects Report #4924537-1
Trisenox side effect was reported by a Physician from JAPAN on Feb 06, 2006. Male patient, 24 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: blood potassium decreased, delirium, depressed level of consciousness, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hypoaesthesia, prothrombin time shortened. Trisenox dosage: 12.45 MG QD INTRAVENOUS DRIP. During the same period patient was treated with VANCOMYCIN HYDROCHLORIDE, MICAFUNGIN, BIAPENEM, AMIKACIN SULPHATE, MIRIMOSTIM, ALLOPURINOL. Patient recovered.