Trisenox and condition aggravated Patient Reports February 13, 2012

Trisenox Side Effects Report #4747951-6
Trisenox side effect was reported by a Health Professional from UNITED STATES on Aug 05, 2005. Female patient, 62 years of age, was diagnosed with multiple myeloma  and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, hyperglycaemia, hypertension, neuropathy peripheral, tremor. Trisenox dosage: (14 MG, QD), IVI. During the same period patient was treated with MELPHALAN, ASCORBIC ACID, DEXAMETHASONE, KYTRIL, MIACALCIN, CALCIUM GLUCONATE, AREDIA, ZOMETA. Patient recovered.

Trisenox Side Effects Report #5245997-5
Trisenox side effect was reported by a Physician from JAPAN on Feb 02, 2007. Female patient, 85 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia, condition aggravated, disseminated intravascular coagulation, respiratory distress, sepsis . Trisenox dosage: 5 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE, DANAPAROID, FUROSEMIDE, SPIRONOLACTONE, NICORANDIL, AMLODIPNE BESILATE, FAMOTIDINE, ALLOPURINOL. Patient recovered.

Trisenox Side Effects Report #5320876-3
Trisenox side effect was reported by a Physician from JAPAN on Apr 24, 2007. Male patient, 73 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia, cerebral haemorrhage, cheilitis, chills, condition aggravated, disseminated intravascular coagulation, hyperhidrosis, pyrexia, rash . Trisenox dosage: 9.075 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FAMOTIDINE, CANDESARTAN CILEXETIL, MEROPENEM TRIHYDRATE, LENOGRASTIM. Patient was hospitalized. Patient died on 03/22/2007.

Trisenox Side Effects Report #5325380-4
Trisenox side effect was reported by a Physician from JAPAN on Apr 26, 2007. Female patient, 73 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: altered state of consciousness, blood bilirubin increased, cerebral haemorrhage, condition aggravated, dialysis , disseminated intravascular coagulation, hyperglycaemia, leukocytosis, pulmonary haemorrhage. Trisenox dosage: 7.62 MG QD INTRAVENOUS DRIP. During the same period patient was treated with ETOPOSIDE, TEICOPLANIN, NAFAMOSTAT MESILATE, MICONAZOLE, HYDROCORTISONE SUCCINATE, FAMOTIDINE. Patient died on 11/09/2005.


Trisenox Side Effects Report #5325386-5
Trisenox side effect was reported by a Physician from JAPAN on Apr 24, 2007. Male patient, 73 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: altered state of consciousness, cerebral hypoperfusion, cerebral infarction, condition aggravated, dysarthria, dysphagia, electrocardiogram qt prolonged, haemodialysis, renal failure. Trisenox dosage: 10.05 MG QD INTRAVENOUS DRIP. During the same period patient was treated with TRETINOIN, GABEXATE MESILATE, DALTEPARIN, GABEXATE MESILATE, CALCIUM GLUCONATE. Patient recovered.

Trisenox Side Effects Report #4609439-2
Trisenox side effect was reported by a Physician from on Feb 21, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #4618289-2
Trisenox side effect was reported by a Physician from on Mar 02, 2005. Female patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, condition aggravated, gamma-glutamyltransferase increased, haemoglobin decreased, hepatic function abnormal. Trisenox dosage: unknown. Patient recovered.

Trisenox Side Effects Report #4781090-3
Trisenox side effect was reported by a Physician from JAPAN on Sept 07, 2005. Male patient, 72 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, hypokalaemia. Trisenox dosage: 6 MG (6 MG, IVI). During the same period patient was treated with BIAPENEM, VANCOMYCIN, CLINDAMYCIN, CEFTAZIDIME, ALLOPURINOL, TOSUFOXACIN, FLUCONAZOLE, FAMOTIDINE. Patient recovered.

Trisenox Side Effects Report #5622337-0
Trisenox side effect was reported by a Physician from JAPAN on Jan 22, 2008. Male patient, 68 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, electrocardiogram qt prolonged, lung disorder, respiratory failure. Trisenox dosage: 8.1 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN, DALTEPARIN, TRANEXAMIC ACID, FUROSEMIDE, POTASSIUM REPLACEMENT. Patient died on 01/02/2008.


Trisenox Side Effects Report #4732834-8
Trisenox side effect was reported by a Physician from JAPAN on July 12, 2005. Male patient, 63 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: central nervous system lesion, condition aggravated, depressed level of consciousness, disseminated intravascular coagulation, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, hypocalcaemia, hyponatraemia, leukocytosis. Trisenox dosage: unknown. During the same period patient was treated with DAUNORUBICIN HYDROCHLORIDE, ITRACONAZOLE, SULFAMETHOXAZOLE, DALTEPARIN, METHOTREXATE, CYTARABINE. Patient recovered.

Trisenox Side Effects Report #5220983-X
Trisenox side effect was reported by a Physician from JAPAN on Jan 09, 2007. Female patient, 62 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, condition aggravated, gamma-glutamyltransferase increased, hepatic function abnormal, leukocytosis. Trisenox dosage: 8.19 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN HDYROCHLORIDE, CYTARABINE, DANAPAROID. Patient recovered.

Trisenox Side Effects Report #5127284-9
Trisenox side effect was reported by a Physician from JAPAN on Sept 26, 2006. Female patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: aspartate aminotransferase increased, c-reactive protein increased, condition aggravated, electrocardiogram qt prolonged, hepatic function abnormal, rash , white blood cell count decreased. Trisenox dosage: 9.15 MG QD INTRAVENOUS DRIP. During the same period patient was treated with SULFAMETHOXAZOLE, FLUCONAZOLE. Patient recovered.

Trisenox Side Effects Report #4758956-3
Trisenox side effect was reported by a Health Professional from JAPAN on Aug 11, 2005. Male patient, 61 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, electrocardiogram qt corrected interval prolonged, electrocardiogram qt prolonged, pancytopenia. Trisenox dosage: 9.3 MG QD INTRAVENOUS DRIP. During the same period patient was treated with AMOXICILLIN AND CLAVULANATE POTASSIUM, ASCORBIC ACIDQ, CALCIUM PANTOTHENATE, DANAPAROID, GABEXATE MESILATE. Patient recovered.

Trisenox Side Effects Report #4732841-5
Trisenox side effect was reported by a Physician from JAPAN on July 12, 2005. Female patient, 60 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, haemoglobin decreased, leukopenia, neutropenia. Trisenox dosage: 8.85 MG (8.85 MG), IVI. Patient recovered.


Trisenox Side Effects Report #5125019-7
Trisenox side effect was reported by a Physician from JAPAN on Sept 22, 2006. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood bilirubin increased, cerebral haemorrhage, condition aggravated, disseminated intravascular coagulation, hepatic function abnormal, hypercalcaemia, hyperglycaemia, hyponatraemia. Trisenox dosage: 9 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE, DANAPAROID, FUROSEMIDE, VORICONAZOLE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient died on 05/16/2006.

Trisenox Side Effects Report #5179504-2
Trisenox side effect was reported by a Physician from JAPAN on Nov 30, 2006. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood bilirubin increased, cerebral haemorrhage, condition aggravated, disseminated intravascular coagulation, febrile neutropenia, fungal infection , hepatic function abnormal, hypercalcaemia. Trisenox dosage: 9 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE, DANAPAROID, FUROSEMIDE, VORICONAZOLE, SULFAMETHOXAZOLE W. Patient was hospitalized. Patient died on 05/16/2006.

Trisenox Side Effects Report #5197209-9
Trisenox side effect was reported by a Physician from JAPAN on Dec 12, 2006. Male patient, 58 years of age, weighting 132.3 lb, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, condition aggravated, disseminated intravascular coagulation, febrile neutropenia, fungal infection , hypercalcaemia, hyperglycaemia, hyponatraemia, oliguria. Trisenox dosage: 9 MG QD INTRAVENOUS DRIP. During the same period patient was treated with GABEXATE MESILATE, DANAPAROID, FUROSEMIDE, VORICONAZOLE, SULFAMETHOXAZOLE. Patient was hospitalized. Patient died on 05/16/2006.

Trisenox Side Effects Report #5266132-3
Trisenox side effect was reported by a Physician from JAPAN on Feb 27, 2007. Female patient, 57 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia differentiation syndrome, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood bilirubin increased, blood lactate dehydrogenase increased, c-reactive protein increased, condition aggravated, disseminated intravascular coagulation. Trisenox dosage: unknown. During the same period patient was treated with CYTARABINE, IDARUBICIN, DANAPAROID, CARBAZOCHROME SULFONATE, TRANEXAMIC ACID, MONOAMMONIUM GLYCYRRHIZINATE. Patient died on 12/31/2006.

Trisenox Side Effects Report #5084863-5
Trisenox side effect was reported by a Physician from JAPAN on July 31, 2006. Male patient, 50 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: acute promyelocytic leukaemia, condition aggravated, headache , leukaemic infiltration brain, leukocytosis, myalgia, promyelocyte count increased, pyrexia, subarachnoid haemorrhage. Trisenox dosage: 11.692 MG QD INTRAVENOUS DRIP. During the same period patient was treated with IDARUBICIN. Patient recovered.


Trisenox Side Effects Report #4892030-0
Trisenox side effect was reported by a Physician from JAPAN on Jan 10, 2006. Female patient, 41 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, disseminated intravascular coagulation, leukocytosis, leukopenia. Trisenox dosage: 7.32 MG QD INTRAVENOUS DRIP. Patient recovered.

Trisenox Side Effects Report #4903384-0
Trisenox side effect was reported by a Physician from JAPAN on Jan 25, 2006. Female patient, 41 years of age, was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, disseminated intravascular coagulation, leukocytosis, leukopenia. Trisenox dosage: 7.32 MG QD INTRAVENOUS DRIP. During the same period patient was treated with FAMOTIDINE, HEPARIN, IDARUBICIN, FUROSEMIDE. Patient was hospitalized. Patient recovered.

Trisenox Side Effects Report #5391723-9
Trisenox side effect was reported by a Physician from JAPAN on July 10, 2007. Male patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: altered state of consciousness, blood creatinine increased, cerebral hypoperfusion, cerebral infarction, condition aggravated, dysarthria, dysphagia, electrocardiogram qt prolonged, haemodialysis. Trisenox dosage: 10.05 MG QD INTRAVENOUS DRIP. During the same period patient was treated with TRETINOIN, GABEXATE MESILATE, DALTEPARIN, GABEXATE MESILATE, CALCIUM GLUCONATE. Patient recovered.

Trisenox Side Effects Report #5603320-8
Trisenox side effect was reported by a Physician from JAPAN on Jan 09, 2008. Female patient was diagnosed with acute promyelocytic leukaemia and was treated with Trisenox. After drug was administered, patient experienced the following side effects: condition aggravated, liver disorder, lung disorder. Trisenox dosage: unknown. During the same period patient was treated with TRETINOIN. Patient died.