Trimethoprim and international normalised ratio increased Patient Reports February 11, 2012

Trimethoprim Side Effects Report #5219297-3
Trimethoprim side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 11, 2007. Male patient, 84 years of age, was diagnosed with urinary tract infection , atrial fibrillation  and was treated with Trimethoprim. After drug was administered, patient experienced the following side effects: haematemesis, haemoglobin decreased, international normalised ratio increased. Trimethoprim dosage: 400 MG (200 MG, 2 IN 1 D). During the same period patient was treated with WARFARIN. Patient was hospitalized. Patient recovered.

Trimethoprim Side Effects Report #5224921-5
Trimethoprim side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Jan 16, 2007. Male patient, 84 years of age, was diagnosed with urinary tract infection , atrial fibrillation  and was treated with Trimethoprim. After drug was administered, patient experienced the following side effects: haematemesis, haemoglobin decreased, international normalised ratio increased. Trimethoprim dosage: 200 MG, BID, ORAL. During the same period patient was treated with WARFARIN, ATENOLOL, CODEINE SUL, DOCUSATE, LACTULOSE, PERINDOPRIL ERBUMINE, SENNA, SIMVASTATIN. Patient was hospitalized. Patient recovered.

Trimethoprim Side Effects Report #4988397-5
Trimethoprim side effect was reported by a Physician from UNITED KINGDOM on Apr 20, 2006. Female patient, 60 years of age, was diagnosed with urinary tract infection , pulmonary embolism  and was treated with Trimethoprim. After drug was administered, patient experienced the following side effects: deep vein thrombosis , hypovolaemic shock, international normalised ratio increased, muscle haemorrhage, prothrombin time prolonged, pyrexia, retroperitoneal haematoma, white blood cell count increased. Trimethoprim dosage: unknown. During the same period patient was treated with METRONIDAZOLE, CEPHALEXIN, NIFEDIPINE, ACEBUTOLOL, INDAPAMIDE, WARFARIN. Patient recovered.

Trimethoprim Side Effects Report #5005142-8
Trimethoprim side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Apr 20, 2006. Female patient, 60 years of age, was diagnosed with urinary tract infection , pulmonary embolism  and was treated with Trimethoprim. After drug was administered, patient experienced the following side effects: deep vein thrombosis , hypovolaemic shock, international normalised ratio increased, muscle haemorrhage, pain , retroperitoneal haematoma, ureteral disorder. Trimethoprim dosage: unknown. During the same period patient was treated with METRONIDAZOLE, WARFARIN, CEPHALEXIN, NIFEDIPINE, ACEBUTOLOL, INDAPAMIDE. Patient was hospitalized. Patient recovered.


Trimethoprim Side Effects Report #5012055-4
Trimethoprim side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 13, 2006. Female patient, 60 years of age, was diagnosed with urinary tract infection , pulmonary embolism  and was treated with Trimethoprim. After drug was administered, patient experienced the following side effects: abdominal pain , deep vein thrombosis , haemoglobin decreased, hypovolaemic shock, international normalised ratio increased, muscle haemorrhage, pyrexia, retroperitoneal haematoma. Trimethoprim dosage: unknown. During the same period patient was treated with METRONIDAZOLE, CEPHALEXIN, WARFARIN. Patient was hospitalized. Patient recovered.

Trimethoprim Side Effects Report #5020729-4
Trimethoprim side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on May 17, 2006. Female patient, 60 years of age, was diagnosed with urinary tract infection  and was treated with Trimethoprim. After drug was administered, patient experienced the following side effects: abdominal pain , deep vein thrombosis , haematoma, haemoglobin decreased, hypovolaemic shock, international normalised ratio increased, muscle haemorrhage, pyrexia. Trimethoprim dosage: unknown. During the same period patient was treated with METRONIDAZOLE, CEPHALEXIN. Patient was hospitalized. Patient recovered.

Trimethoprim Side Effects Report #5455298-8
Trimethoprim side effect was reported by a Pharmacist from UNITED STATES on Sept 13, 2007. Male patient, 75 years of age, was diagnosed with infection  and was treated with Trimethoprim. After drug was administered, patient experienced the following side effects: international normalised ratio increased. Trimethoprim dosage: 160MG BID IV. During the same period patient was treated with LEVOFLOXACIN. Patient was hospitalized. Patient recovered.

Trimethoprim Side Effects Report #5507338-5
Trimethoprim side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Oct 18, 2007. Female patient, 76 years of age, was treated with Trimethoprim. After drug was administered, patient experienced the following side effects: contusion, international normalised ratio increased. Trimethoprim dosage: (200 MG) ORAL. During the same period patient was treated with PEGAPTANIB. Patient was hospitalized. Patient recovered.