Trastuzumab and ejection fraction decreased Patient Reports February 11, 2012

Trastuzumab Side Effects Report #4664142-8
Trastuzumab side effect was reported by a Physician from on May 16, 2005. Female patient, weighting 132.0 lb, was diagnosed with breast cancer stage ii and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: chronic obstructive pulmonary disease, cough, ejection fraction decreased, rhonchi, wheezing. Trastuzumab dosage: 120MG DAYS 1,8,15,22 INTRAVENOUS. Patient recovered.

Trastuzumab Side Effects Report #5296028-2
Trastuzumab side effect was reported by a Health Professional from GREECE on Mar 21, 2007. Female patient, 72 years of age, was diagnosed with breast cancer metastatic and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: blood bilirubin increased, breast cancer metastatic, diarrhoea, ejection fraction decreased, liver disorder, malignant neoplasm progression. Trastuzumab dosage: 2 MG/KG, UNK, INTRAVENOUS. During the same period patient was treated with LAPATINIB. Patient died on 01/19/2007.

Trastuzumab Side Effects Report #4844541-1
Trastuzumab side effect was reported by a Physician from UNITED STATES on Nov 30, 2005. Female patient, 49 years of age, weighting 197.0 lb, was diagnosed with breast cancer metastatic and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: asthenia, cardiac failure congestive, cardiogenic shock, cardiomyopathy , dilatation ventricular, dysphonia, ejection fraction decreased, fatigue, hypotension. Trastuzumab dosage: 191 MG QWK IV. During the same period patient was treated with BEVACIZUMAB, NIFEDIPINE, GREEN FOOD, ATIVAN, ORIGINS, PAXIL. Patient was hospitalized. Patient recovered.

Trastuzumab Side Effects Report #5356016-4
Trastuzumab side effect was reported by a Physician from UNITED KINGDOM on May 30, 2007. Female patient was diagnosed with breast cancer metastatic and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: ejection fraction decreased, hepatotoxicity. Trastuzumab dosage: 8 MG/KG, Q3W. During the same period patient was treated with VINORELBINE. Patient recovered.


Trastuzumab Side Effects Report #5307282-2
Trastuzumab side effect was reported by a Physician from UNITED KINGDOM on Apr 13, 2007. Female patient, weighting 196.2 lb, was diagnosed with breast cancer  and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: ejection fraction decreased, syncope, tachycardia. Trastuzumab dosage: 680 MG, UNK. During the same period patient was treated with CAPECITABINE, DOCETAXEL, EPIRUBICIN, CYCLOPHOSPHAMIDE, FRAXIPARIN, METOCLOPRAMIDE, DIMENHYDRINATE. Patient was hospitalized. Patient recovered.

Trastuzumab Side Effects Report #5950687-7
Trastuzumab side effect was reported by a Physician from UNITED KINGDOM on Oct 31, 2008. Female patient was diagnosed with breast cancer  and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: chest pain , ejection fraction decreased, tachycardia. Trastuzumab dosage: 4 MG/KG, SINGLE. During the same period patient was treated with BISOPROLOL FUMARATE, ANASTROZOLE, FUMARIC ACID, MAGNESIUM CARBONATE, MAGNESIUM CHLORIDE, EUNOVA. Patient was hospitalized. Patient recovered.

Trastuzumab Side Effects Report #5449127-6
Trastuzumab side effect was reported by a Physician from UNITED KINGDOM on Aug 29, 2007. Female patient was diagnosed with breast cancer metastatic and was treated with Trastuzumab. After drug was administered, patient experienced the following side effects: disease progression, ejection fraction decreased. Trastuzumab dosage: 2 MG/KG, 1/WEEK. During the same period patient was treated with LAPATINIB. Patient died on 01/19/2007.