Topotecan and haemoglobin decreased Patient Reports February 11, 2012

Topotecan Side Effects Report #4725529-8
Topotecan side effect was reported by a Pharmacist from UNITED STATES on July 22, 2005. Female patient, 76 years of age, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, haematocrit decreased, haemoglobin decreased, international normalised ratio increased, petechiae, platelet count decreased. Topotecan dosage: unknown. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4594170-2
Topotecan side effect was reported by a Physician from on Jan 12, 2005. Female patient, 65 years of age, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: gastrointestinal motility disorder, haemoglobin decreased, infrequent bowel movements, international normalised ratio increased, nausea , nodule, peritoneal disorder, platelet count increased, subileus. Topotecan dosage: 4MG PER DAY. During the same period patient was treated with GEMCITABINE, ZOPHREN, LIPANTHYL, ESBERIVEN, PRAXILENE, PREVISCAN, PLITICAN, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5253103-6
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 28, 2007. Female patient, 57 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chest pain , condition aggravated, decreased appetite, dehydration, diarrhoea, dyspnoea, haematocrit decreased, haemoglobin decreased, heart rate increased. Topotecan dosage: 2.16MG CYCLIC. During the same period patient was treated with ERLOTINIB, ATIVAN, ANZEMET, ARANESP. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5052556-6
Topotecan side effect was reported by a Physician from UNITED STATES on June 29, 2006. Female patient was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal distension, dizziness , haemoglobin decreased, neutropenia. Topotecan dosage: 3.5MGM2 CYCLIC. During the same period patient was treated with TAXOTERE, COUMADIN, ATENOLOL. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5112711-3
Topotecan side effect was reported by a Physician from GERMANY on Sept 18, 2006. Female patient, weighting 222.7 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, haemoglobin decreased, leukopenia, platelet count decreased, thrombocytopenia, white blood cell count decreased. Topotecan dosage: 2.48MG PER DAY. During the same period patient was treated with BELOC ZOK, DELIX, TORSEMIDE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5157506-X
Topotecan side effect was reported by a Physician from GERMANY on Sept 18, 2006. Female patient, weighting 222.7 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, haemoglobin decreased, leukopenia, platelet count decreased, thrombocytopenia, white blood cell count decreased. Topotecan dosage: 2.48MG PER DAY. During the same period patient was treated with BELOC ZOK, DELIX, TORSEMIDE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5494950-5
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 22, 2007. Male patient, 60 years of age, was diagnosed with neoplasm and was treated with Topotecan. After drug was administered, patient experienced the following side effects: epistaxis, haematuria, haemoglobin decreased, headache , neutrophil toxic granulation present, platelet count decreased, rhinitis, sinus congestion, sinus headache. Topotecan dosage: 1.2MGM2 CYCLIC. During the same period patient was treated with DIMETICONE, OMEPRAZOLE, GEMFIBROZIL, TELMISARTAN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5527800-9
Topotecan side effect was reported by a Physician from UNITED STATES on Nov 21, 2007. Male patient, 60 years of age, was diagnosed with neoplasm and was treated with Topotecan. After drug was administered, patient experienced the following side effects: epistaxis, haematuria, haemoglobin decreased, headache , neutrophil toxic granulation present, platelet count decreased, rhinitis, sinus congestion, sinus headache. Topotecan dosage: 1.2MGM2 CYCLIC. During the same period patient was treated with DIMETICONE, OMEPRAZOLE, GEMFIBROZIL, TELMISARTAN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5527837-X
Topotecan side effect was reported by a Physician from UNITED STATES on Nov 21, 2007. Male patient, 60 years of age, was diagnosed with neoplasm and was treated with Topotecan. After drug was administered, patient experienced the following side effects: epistaxis, flank pain, haematuria, haemoglobin decreased, headache , neutrophil toxic granulation present, platelet count decreased, rhinitis, sinus congestion. Topotecan dosage: 1.2MGM2 CYCLIC. During the same period patient was treated with DIMETICONE, OMEPRAZOLE, GEMFIBROZIL, TELMISARTAN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4683367-9
Topotecan side effect was reported by a Health Professional from on June 06, 2005. Male patient, 71 years of age, weighting 203.0 lb, was diagnosed with malignant neoplasm of islets of langerhans and was treated with Topotecan. After drug was administered, patient experienced the following side effects: catheter related infection, coronary artery atherosclerosis, dyspnoea exertional, haemoglobin decreased, streptococcal bacteraemia. Topotecan dosage: unknown. During the same period patient was treated with COUMADIN, ATENOLOL, SPIRONOLACTONE, INSULIN, FOSINOPRIL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5040813-9
Topotecan side effect was reported by a Health Professional from UNITED STATES on June 29, 2006. Female patient, 66 years of age, weighting 119.9 lb, was diagnosed with disease recurrence, ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dizziness , haematocrit decreased, haemoglobin decreased, hypotension. Topotecan dosage: 3.5 MG/M2 WEEKLY X 3 IV DRIP. During the same period patient was treated with TAXOTERE. Patient recovered.

Topotecan Side Effects Report #5605607-1
Topotecan side effect was reported by a Health Professional from UNITED STATES on Jan 25, 2008. Female patient, weighting 135.3 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: haematocrit decreased, haemoglobin decreased, vaginal haemorrhage. Topotecan dosage: unknown. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4758768-0
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 31, 2005. Female patient, weighting 193.8 lb, was diagnosed with cervix carcinoma, squamous cell carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: cervix carcinoma recurrent, dizziness , fatigue, haematocrit decreased, haemoglobin decreased, neutrophil count decreased, platelet count decreased, squamous cell carcinoma, white blood cell count decreased. Topotecan dosage: unknown. During the same period patient was treated with CISPLATIN, TOPROL, LISINOPRIL, LANTUS. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4762178-X
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 06, 2005. Female patient, weighting 139.0 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: constipation , haemoglobin decreased, hydronephrosis, urinary tract infection . Topotecan dosage: 0.98 MG/DAY 1-5, IV. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4876071-5
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 06, 2006. Female patient, weighting 119.2 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood magnesium decreased, cervix carcinoma recurrent, haemoglobin decreased, oedema peripheral, ureteric obstruction. Topotecan dosage: unknown. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4768744-X
Topotecan side effect was reported by a Physician from JAPAN on Sept 05, 2005. Male patient, 77 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, haemoglobin decreased, platelet count decreased, red blood cell count decreased, respiratory failure, white blood cell count decreased. Topotecan dosage: 1MG PER DAY. During the same period patient was treated with CEFTRIAXZONE, RINGERS ACETATE, CARBAZOCHROME SULFONATE, TRANEXAMIC ACID, ONDANSETRON, LANSOPRAZOLE, ASPIRIN, LACTOMIN. Patient died on 12/05/2002.

Topotecan Side Effects Report #5477201-7
Topotecan side effect was reported by a Health Professional from JAPAN on Oct 02, 2007. Male patient, 76 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: haemoglobin decreased, neutrophil count decreased, neutrophil count increased, platelet count decreased, red blood cell count decreased, white blood cell count increased. Topotecan dosage: 2MG PER DAY. During the same period patient was treated with NEUPOGEN, ZOFRAN. Patient recovered.

Topotecan Side Effects Report #5520854-5
Topotecan side effect was reported by a Health Professional from JAPAN on Nov 16, 2007. Male patient, 76 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: haemoglobin decreased, neutrophil count decreased, platelet count decreased, red blood cell count decreased, white blood cell count decreased. Topotecan dosage: 2MG PER DAY. During the same period patient was treated with NEUPOGEN, ZOFRAN. Patient recovered.

Topotecan Side Effects Report #4781267-7
Topotecan side effect was reported by a Physician from JAPAN on Sept 14, 2005. Male patient, 76 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, haemoglobin decreased, neutrophil count decreased, platelet count decreased, red blood cell count decreased, white blood cell count decreased. Topotecan dosage: unknown. During the same period patient was treated with AMRUBICIN HYDROCHLORIDE, GRANISETRON, ZOLPIDEM TARTRATE, MAGNESIUM OXIDE, NORFLOXACIN, CEFDINIR, FILGRASTIM, CEFAZOLIN. Patient recovered.


Topotecan Side Effects Report #4791700-2
Topotecan side effect was reported by a Physician from JAPAN on Sept 14, 2005. Male patient, 76 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, blood alkaline phosphatase increased, blood lactate dehydrogenase increased, haemoglobin decreased, neutrophil count decreased, platelet count decreased, red blood cell count decreased, white blood cell count decreased. Topotecan dosage: unknown. During the same period patient was treated with AMRUBICIN HYDROCHLORIDE, GRANISETRON, ZOLPIDEM TARTRATE, MAGNESIUM OXIDE, NORFLOXACIN, CEFDINIR, FILGRASTIM, CEFAZOLIN. Patient recovered.

Topotecan Side Effects Report #5208979-5
Topotecan side effect was reported by a Physician from GERMANY on Jan 12, 2007. Male patient, 74 years of age, weighting 187.4 lb, was diagnosed with hypertension and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, c-reactive protein increased, cough, haemoglobin decreased, hypokalaemia, nausea , platelet count decreased, productive cough. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, FENTANYL TRANSDERMAL SYSTEM, CAPTOPRIL, PRAVASTATIN, THEOPHYLLINE, ALLOPURINOL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4770847-0
Topotecan side effect was reported by a Physician from JAPAN on Sept 05, 2005. Male patient, 71 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, blood lactate dehydrogenase increased, haemoglobin decreased, liver disorder, neutrophil count decreased, platelet count decreased, pre-existing disease, red blood cell count decreased, white blood cell count decreased. Topotecan dosage: 1.43MG PER DAY. During the same period patient was treated with AMRUBICIN HYDROCHLORIDE, GRANISETRON, SOLITA, AMINOPHYLLINE, METHYLPREDNISOLONE SUCCINATE, LENOGRASTIM, REBAMIPIDE, GLIMEPIRIDE. Patient was hospitalized. Patient died on 10/19/2004.

Topotecan Side Effects Report #4766051-2
Topotecan side effect was reported by a Health Professional from JAPAN on Sept 07, 2005. Male patient, 63 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: haemoglobin decreased, lung neoplasm, neutropenia, platelet count decreased. Topotecan dosage: 1.3MG PER DAY. During the same period patient was treated with AMRUBICIN HYDROCHLORIDE, LENOGRASTIM, GRANISETRON, MAGNESIUM OXIDE, CLARITHROMYCIN, CARBAZOCHROME SULFONATE, TRANEXAMIC ACID, LEVOFLOXACIN. Patient was hospitalized. Patient died on 04/19/2005.

Topotecan Side Effects Report #4779967-8
Topotecan side effect was reported by a Physician from JAPAN on Sept 14, 2005. Male patient, 61 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: haemoglobin decreased, leukopenia, reticulocyte count decreased, thrombocytopenia. Topotecan dosage: 1.1MG PER DAY. During the same period patient was treated with CARBOPLATIN, NARTOGRASTIM. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4698164-8
Topotecan side effect was reported by a Physician from on Apr 06, 2005. Female patient, 60 years of age, weighting 136.7 lb, was diagnosed with prophylaxis and was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood glucose increased, bronchial obstruction, dyspnoea exacerbated, haematocrit decreased, haemoglobin decreased, lung neoplasm malignant, lymphangiosis carcinomatosa, malignant neoplasm progression, pneumonia . Topotecan dosage: 1.22MG PER DAY. During the same period patient was treated with CISPLATIN, METOCLOPRAMIDE HYDROCHLORIDE. Patient was hospitalized. Patient died on 05/05/2005.

Topotecan Side Effects Report #4785569-X
Topotecan side effect was reported by a Physician from GERMANY on May 30, 2005. Male patient, 59 years of age, weighting 172.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: angina pectoris, blood potassium decreased, cardiac disorder, diarrhoea, haemoglobin decreased, hypovolaemia, pancreatitis, vomiting. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, CONCOR, NOVALGIN, PASPERTIN, PANTOZOL, ENALAPRIL, CEFOTIAM HYDROCHLORIDE. Patient was hospitalized. Patient died on 08/17/2005.

Topotecan Side Effects Report #4730170-7
Topotecan side effect was reported by a Physician from UNITED STATES on July 22, 2005. Female patient, 53 years of age, weighting 152.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: haematocrit decreased, haematuria, haemoglobin decreased, neutropenia, pyrexia, thrombocytopenia. Topotecan dosage: .75MGM2 CYCLIC. During the same period patient was treated with CISPLATIN, ALLEGRA, FOLATE, VICODIN, ZOFRAN, AMBIEN, ATIVAN, SERZONE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4770843-3
Topotecan side effect was reported by a Physician from JAPAN on Sept 05, 2005. Female patient, 53 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, haemoglobin decreased, leukopenia, pancytopenia, vomiting. Topotecan dosage: unknown. During the same period patient was treated with ZOPICLONE, SENNOSIDE, GRANISETRON, PICOSULPHATE, BROTIZOLAM, MORPHINE HYDROCHLORIDE, LOXOPROFEN, REBAMIPIDE. Patient died on 12/15/2003.

Topotecan Side Effects Report #5486888-4
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 12, 2007. Female patient, weighting 158.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: activities of daily living impaired, decreased appetite, failure to thrive, fatigue, haemoglobin decreased, nausea , oral intake reduced, pyrexia. Topotecan dosage: 11 MG. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4727252-2
Topotecan side effect was reported by a Physician from UNITED STATES on July 22, 2005. Female patient, weighting 99.21 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: haemoglobin decreased, vaginal haemorrhage. Topotecan dosage: .75MGM2 CYCLIC. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 04/22/2002.

Topotecan Side Effects Report #5027785-8
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 14, 2006. Female patient, weighting 104.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, bedridden, decreased appetite, dehydration, fatigue, haemoglobin decreased, hypomagnesaemia, hyponatraemia, nausea . Topotecan dosage: 12 MG. Patient was hospitalized. Patient recovered.