Topotecan and fatigue Patient Reports February 11, 2012

Topotecan Side Effects Report #5256466-0
Topotecan side effect was reported by a Physician from UNITED STATES on Mar 01, 2007. Male patient, 53 years of age, weighting 238.5 lb, was diagnosed with small cell lung cancer metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, disorientation, fatigue, mental status changes. Topotecan dosage: 3MGM2 CYCLIC. During the same period patient was treated with BORTEZOMIB. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5975846-9
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 02, 2008. Female patient, 60 years of age, weighting 160.1 lb, was diagnosed with ovarian cancer recurrent and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cough, dizziness , dyspnoea, fatigue, pleural effusion, pneumonitis. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with BEVACIZUMAB, LEVOFLOXACIN, FEXOFENADINE, LORAZEPAM, DEXAMETHASONE, PRILOSEC, SUDAFED, TYLENOL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4728740-5
Topotecan side effect was reported by a Physician from CANADA on July 25, 2005. Female patient, 71 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, fatigue, intestinal perforation, neutropenia, pyrexia, sepsis , urinary tract infection . Topotecan dosage: .75MGM2 CYCLIC. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 07/21/2005.

Topotecan Side Effects Report #5157493-4
Topotecan side effect was reported by a Physician from GERMANY on Nov 17, 2005. Female patient, 64 years of age, weighting 152.1 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood potassium decreased, fatigue, ileus, vomiting. Topotecan dosage: 2.18MG PER DAY. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5219159-1
Topotecan side effect was reported by a Physician from GERMANY on Jan 19, 2007. Female patient, 59 years of age, weighting 141.1 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, condition aggravated, fatigue, feeling abnormal, ileus. Topotecan dosage: 6.92MG WEEKLY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5167104-X
Topotecan side effect was reported by a Physician from GERMANY on Sept 22, 2006. Female patient, 46 years of age, weighting 160.9 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: fatigue, peripheral sensory neuropathy. Topotecan dosage: 7MG WEEKLY. During the same period patient was treated with KEVATRIL, FORTECORTIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5157495-8
Topotecan side effect was reported by a Physician from GERMANY on Dec 30, 2005. Female patient, weighting 148.8 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: fatigue, malignant ascites. Topotecan dosage: unknown. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5167105-1
Topotecan side effect was reported by a Physician from GERMANY on Oct 04, 2006. Female patient, weighting 160.9 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: fatigue, peripheral sensory neuropathy. Topotecan dosage: 7MG WEEKLY. During the same period patient was treated with KEVATRIL, FORTECORTIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5717988-9
Topotecan side effect was reported by a Physician from GERMANY on Apr 18, 2008. Female patient, weighting 154.3 lb, was diagnosed with neoplasm malignant, hypertonia, bone pain and was treated with Topotecan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, fatigue, mucosal inflammation, nausea . Topotecan dosage: unknown. During the same period patient was treated with ATENOLOL, BUPRENORPHINE. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5380752-7
Topotecan side effect was reported by a Physician from HUNGARY on July 04, 2007. Female patient, 64 years of age, weighting 174.2 lb, was diagnosed with metastases to central nervous system and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, bedridden, fatigue, heart rate increased, impaired self-care, leukopenia, neutropenia, pancytopenia. Topotecan dosage: 1.1MGM2 PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4821271-3
Topotecan side effect was reported by a Health Professional from UNITED STATES on Nov 04, 2005. Female patient, 23 years of age, weighting 153.7 lb, was diagnosed with cervix carcinoma stage ii and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, back pain , blood creatinine increased, fatigue, hydronephrosis, respiratory rate increased. Topotecan dosage: 0.15 MG/M2 CONT IV. During the same period patient was treated with CISPLATIN, BENADRYL, PERCOCET. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5530651-2
Topotecan side effect was reported by a Physician from GERMANY on Nov 23, 2007. Female patient, 30 years of age, weighting 121.3 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, fatigue, malnutrition. Topotecan dosage: 2.9MG WEEKLY. During the same period patient was treated with PACLITAXEL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4758768-0
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 31, 2005. Female patient, weighting 193.8 lb, was diagnosed with cervix carcinoma, squamous cell carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: cervix carcinoma recurrent, dizziness , fatigue, haematocrit decreased, haemoglobin decreased, neutrophil count decreased, platelet count decreased, squamous cell carcinoma, white blood cell count decreased. Topotecan dosage: unknown. During the same period patient was treated with CISPLATIN, TOPROL, LISINOPRIL, LANTUS. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5422395-2
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 20, 2007. Male patient, 83 years of age, weighting 188.5 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: accidental poisoning, dehydration, dysuria, fatigue, nausea , renal failure acute. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5468320-X
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 25, 2007. Male patient, 83 years of age, weighting 188.5 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: accidental poisoning, dehydration, disease progression, dysuria, fatigue, nausea , pneumonia , renal failure acute. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 08/25/2007.

Topotecan Side Effects Report #4882231-X
Topotecan side effect was reported by a Health Professional from UNITED STATES on Jan 13, 2006. Female patient, 79 years of age, weighting 122.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, lung infiltration, radiation pneumonitis. Topotecan dosage: 1.5 MG/M2 X 5 DAYS IV X 4 CYCLES. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4891171-1
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 13, 2006. Female patient, 79 years of age, weighting 122.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, hypoxia, radiation pneumonitis. Topotecan dosage: 1.5MGM2 CYCLIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4893705-X
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 13, 2006. Female patient, 79 years of age, weighting 122.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, hypoxia. Topotecan dosage: 1.5MGM2 CYCLIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4894706-8
Topotecan side effect was reported by a Health Professional from UNITED STATES on Jan 27, 2006. Female patient, 79 years of age, weighting 122.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, hypoxia, lung infiltration. Topotecan dosage: 1.5MG/M2 X 5 DAYS IV 4 CYCLES. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5534451-9
Topotecan side effect was reported by a Physician from DENMARK on Nov 28, 2007. Male patient, 74 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: fatigue, febrile neutropenia, malaise, nausea . Topotecan dosage: 3.96MG PER DAY. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 11/13/2007.

Topotecan Side Effects Report #5828622-1
Topotecan side effect was reported by a Physician from UNITED STATES on July 23, 2008. Female patient, 73 years of age, weighting 107.1 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, dehydration, fatigue. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5851104-8
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 14, 2008. Female patient, 73 years of age, weighting 107.1 lb, was diagnosed with sleep disorder  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, dehydration, fatigue. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, AMBIEN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5316893-X
Topotecan side effect was reported by a Physician from DENMARK on Apr 29, 2007. Female patient, 72 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anorexia, blood pressure decreased, body temperature increased, confusional state, dehydration, dizziness , dysphagia, fatigue, fungal infection . Topotecan dosage: 3.2MG PER DAY. During the same period patient was treated with CISPLATIN, MAGNESIUM SULPHATE, METOCLOPRAMIDE, METHYLPREDNISOLONE SUCCINATE, POTASSIUM ACETATE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5330001-0
Topotecan side effect was reported by a Physician from DENMARK on May 14, 2007. Female patient, 72 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anorexia, blood pressure decreased, body temperature increased, confusional state, dehydration, dizziness , dysphagia, fatigue, fungal infection . Topotecan dosage: 3.2MG PER DAY. During the same period patient was treated with CISPLATIN, MAGNESIUM SULPHATE, METOCLOPRAMIDE, METHYLPREDNISOLONE SUCCINATE, POTASSIUM ACETATE. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5016610-7
Topotecan side effect was reported by a Physician from UNITED STATES on May 30, 2006. Male patient, 69 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: cardiac failure congestive, dyspnoea exacerbated, fatigue, oedema, pneumonia . Topotecan dosage: 6.1MG CYCLIC. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient died on 05/29/2006.

Topotecan Side Effects Report #5023511-7
Topotecan side effect was reported by a Physician from UNITED STATES on May 30, 2006. Male patient, 69 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: cardiac failure congestive, dyspnoea exacerbated, fatigue, malignant neoplasm progression, oedema, pneumonia . Topotecan dosage: 6.1MG CYCLIC. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient died on 05/29/2006.

Topotecan Side Effects Report #5376096-X
Topotecan side effect was reported by a Physician from HUNGARY on June 22, 2007. Female patient, 64 years of age, weighting 174.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, fatigue, leukopenia, neutropenia, pancytopenia, pyrexia, syncope, thrombocytopenia. Topotecan dosage: 1.1MGM2 PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5384177-X
Topotecan side effect was reported by a Physician from HUNGARY on July 06, 2007. Female patient, 64 years of age, weighting 174.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, bedridden, fatigue, impaired self-care, leukopenia, neutropenia, pancytopenia, pyrexia. Topotecan dosage: 4MG PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5574931-3
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 21, 2007. Male patient, 61 years of age, was diagnosed with blood pressure , nausea , pain  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, blood potassium decreased, blood sodium decreased, cardiac failure congestive, dyspnoea, fatigue, fluid overload, haematemesis, left ventricular hypertrophy. Topotecan dosage: 7.5MG WEEKLY. During the same period patient was treated with HYDROCORTISONE, FLUDROCORTISONE ACETATE, METOCLOPRAMIDE, HYDROMORPHONE, ARANESP, MAGNESIUM OXIDE, FENTANYL, ZOCOR. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5123876-1
Topotecan side effect was reported by a Physician from EGYPT on Oct 03, 2006. Male patient, 60 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: diabetic coma, fatigue. Topotecan dosage: 2.5MGM2 WEEKLY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4626341-0
Topotecan side effect was reported by a Physician from on Mar 30, 2005. Male patient, 58 years of age, weighting 152.8 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, dehydration, fatigue, weight decreased. Topotecan dosage: 7.8MG CYCLIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4634083-0
Topotecan side effect was reported by a Physician from on Mar 30, 2005. Male patient, 58 years of age, weighting 152.8 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, dehydration, fatigue, weight decreased. Topotecan dosage: 4MGM2 CYCLIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5563146-0
Topotecan side effect was reported by a Physician from GERMANY on Dec 07, 2007. Female patient, 30 years of age, weighting 121.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, fatigue, malnutrition. Topotecan dosage: 2.9MG WEEKLY. During the same period patient was treated with PACLITAXEL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5648676-5
Topotecan side effect was reported by a Physician from GERMANY on Feb 28, 2008. Female patient, 30 years of age, weighting 121.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, fatigue, malnutrition. Topotecan dosage: 2.9MG WEEKLY. During the same period patient was treated with PACLITAXEL, EPOGEN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5256262-4
Topotecan side effect was reported by a Health Professional from UNITED STATES on Mar 02, 2007. Male patient, weighting 238.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, disorientation, fatigue, mental status changes. Topotecan dosage: 3 MG/M2 D 1,8,15 Q28 IV. Patient recovered.

Topotecan Side Effects Report #5313391-4
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 27, 2007. Female patient, weighting 155.9 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain , fatigue, nausea . Topotecan dosage: 8.9 MG. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5333451-1
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on May 22, 2007. Female patient, weighting 155.9 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain , fatigue, haemoglobin abnormal, nausea . Topotecan dosage: 8.9 MG. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5153306-5
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 16, 2006. Female patient, weighting 233.7 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain , dehydration, fatigue, muscle spasms, pulmonary embolism . Topotecan dosage: 12.5 MG. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5486888-4
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 12, 2007. Female patient, weighting 158.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: activities of daily living impaired, decreased appetite, failure to thrive, fatigue, haemoglobin decreased, nausea , oral intake reduced, pyrexia. Topotecan dosage: 11 MG. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5587018-0
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 07, 2008. Female patient was diagnosed with pain  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: alanine aminotransferase abnormal, aspartate aminotransferase abnormal, asthenia, blood creatinine abnormal, decreased appetite, dysphonia, failure to thrive, fatigue, haemoglobin abnormal. Topotecan dosage: 3.3MG CYCLIC. During the same period patient was treated with BEVACIZUMAB, CISPLATIN, VERAPAMIL, HYDROCHLOROTHIAZIDE, METOPROLOL, PERCOCET, MORPHINE, ZOFRAN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5845226-5
Topotecan side effect was reported by a Physician from GERMANY on Aug 12, 2008. Female patient, weighting 154.3 lb, was diagnosed with hypertonia, bone pain and was treated with Topotecan. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, fatigue, mucosal inflammation, nausea . Topotecan dosage: unknown. During the same period patient was treated with ATENOLOL, BUPRENORPHINE, TRANSTEC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4627613-6
Topotecan side effect was reported by a Health Professional from on Apr 01, 2005. Male patient, weighting 152.8 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, dehydration, fatigue, weight decreased. Topotecan dosage: 7.8MG WEEKLY X3 INTRAVENOUS. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5027785-8
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 14, 2006. Female patient, weighting 104.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, bedridden, decreased appetite, dehydration, fatigue, haemoglobin decreased, hypomagnesaemia, hyponatraemia, nausea . Topotecan dosage: 12 MG. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5038669-3
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 27, 2006. Female patient, weighting 104.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abasia, anxiety , asthenia, bedridden, blood culture positive, decreased appetite, dehydration, fatigue, haemoglobin decreased. Topotecan dosage: 12 MG. Patient was hospitalized. Patient recovered.