Topotecan and dyspnoea Patient Reports February 11, 2012

Topotecan Side Effects Report #4827081-5
Topotecan side effect was reported by a Physician from CANADA on Dec 09, 2004. Female patient, 63 years of age, weighting 119.0 lb, was diagnosed with squamous cell carcinoma of the cervix, constipation  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, constipation , disease progression, dyspnoea, hypertension, leukopenia, neutropenic sepsis, respiratory arrest, sinus arrhythmia. Topotecan dosage: 1.4MG PER DAY. During the same period patient was treated with FRAGMIN, LACTULOSE, DILAUDID, LOSEC, NORTRIPTYLINE, NORMAL SALINE. Patient was hospitalized. Patient died on 12/09/2004.

Topotecan Side Effects Report #4761488-X
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 30, 2005. Female patient, 37 years of age, weighting 240.3 lb, was diagnosed with squamous cell carcinoma of the cervix and was treated with Topotecan. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, dyspnoea, neutropenia, pallor, pneumococcal infection, pulmonary embolism , respiratory disorder. Topotecan dosage: .75MGM2 CYCLIC. During the same period patient was treated with CISPLATIN, LEVAQUIN, PREMPRO, NEUPOGEN. Patient was hospitalized. Patient died on 03/05/2001.

Topotecan Side Effects Report #4752170-3
Topotecan side effect was reported by a Health Professional from UNITED STATES on Aug 24, 2005. Female patient, 74 years of age, weighting 161.0 lb, was diagnosed with small cell lung cancer metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea. Topotecan dosage: 7 MG Q WK. During the same period patient was treated with GLUCOTROL, ACCUPRIL, PREVACID, ALBUTEROL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5179332-8
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 15, 2006. Male patient, 66 years of age, weighting 150.4 lb, was diagnosed with small cell lung cancer metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, heart rate increased, lymphadenopathy, pleural effusion, pulmonary mass, tachypnoea. Topotecan dosage: 3MGM2 CYCLIC. During the same period patient was treated with BORTEZOMIB. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5922025-7
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 15, 2008. Male patient, 77 years of age, weighting 182.3 lb, was diagnosed with small cell lung cancer extensive stage, asthma  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, dyspnoea, neutropenia, pyrexia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, FEXOFENADINE, THEOPHYLLINE, AZELASTINE, ALBUTEROL, FLUTICASONE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5950199-0
Topotecan side effect was reported by a Physician from UNITED STATES on Nov 06, 2008. Male patient, 77 years of age, weighting 182.3 lb, was diagnosed with small cell lung cancer extensive stage, asthma  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: confusional state, dyspnoea, neutropenia, pyrexia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, FEXOFENADINE, THEOPHYLLINE, AZELASTINE, ALBUTEROL, FLUTICASONE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5923694-8
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 13, 2008. Female patient, 65 years of age, weighting 181.2 lb, was diagnosed with ovarian cancer recurrent, hypertension, hypothyroidism, restless legs syndrome, therapeutic procedure and was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain lower, chest pain , coronary artery stenosis, dyspnoea, haematemesis, haemorrhage, haemorrhagic anaemia, hyperhidrosis, hypotension. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with BEVACIZUMAB, NORVASC, ATENOLOL, LEVOTHYROXINE, CARBIDOPA AND LEVODOPA, ONDANSETRON, LORAZEPAM. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5975846-9
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 02, 2008. Female patient, 60 years of age, weighting 160.1 lb, was diagnosed with ovarian cancer recurrent and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cough, dizziness , dyspnoea, fatigue, pleural effusion, pneumonitis. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with BEVACIZUMAB, LEVOFLOXACIN, FEXOFENADINE, LORAZEPAM, DEXAMETHASONE, PRILOSEC, SUDAFED, TYLENOL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4577334-3
Topotecan side effect was reported by a Physician from on Jan 28, 2005. Female patient, 79 years of age, weighting 210.5 lb, was diagnosed with ovarian cancer, prophylaxis and was treated with Topotecan. After drug was administered, patient experienced the following side effects: atrial fibrillation , dyspnoea, rash . Topotecan dosage: 1MGM2 CYCLIC. During the same period patient was treated with TAXOL, CARBOPLATIN, ZOFRAN, DECADRON, BENADRYL, CIMETIDINE. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5879393-4
Topotecan side effect was reported by a Physician from FRANCE on Sept 04, 2008. Female patient, 76 years of age, weighting 127.9 lb, was diagnosed with ovarian cancer, vomiting, abdominal pain upper, oedema peripheral, intestinal obstruction and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anorexia, dyspnoea, intestinal obstruction, ovarian cancer, pleural effusion. Topotecan dosage: 5.3MG PER DAY. During the same period patient was treated with LAPATINIB, ANTIEMETICS, ESOMEPRAZOLE, SPIRONOLACTONE, OCTREOTIDE ACETATE, MORPHINE. Patient was hospitalized. Patient died on 09/02/2008.

Topotecan Side Effects Report #4725529-8
Topotecan side effect was reported by a Pharmacist from UNITED STATES on July 22, 2005. Female patient, 76 years of age, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, haematocrit decreased, haemoglobin decreased, international normalised ratio increased, petechiae, platelet count decreased. Topotecan dosage: unknown. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5011259-4
Topotecan side effect was reported by a Health Professional from UNITED STATES on May 23, 2006. Female patient, 76 years of age, weighting 207.2 lb, was diagnosed with ovarian cancer, recurrent cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: ascites, dyspnoea, fluid retention, platelet count decreased, stent placement. Topotecan dosage: 4.95 MG, Q 1WK, IV. During the same period patient was treated with LOVENOX, TYLENOL. Patient was hospitalized. Patient died on 03/20/2006.

Topotecan Side Effects Report #5908737-X
Topotecan side effect was reported by a Physician from FRANCE on Sept 26, 2008. Female patient, 58 years of age, weighting 97.00 lb, was diagnosed with ovarian cancer, anxiety  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: aspiration, dyspnoea, vomiting. Topotecan dosage: 3.2MGM2 PER DAY. During the same period patient was treated with LAPATINIB, LEXOMIL, ATARAX. Patient died on 09/13/2008.

Topotecan Side Effects Report #5248099-7
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 26, 2007. Female patient, 57 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chest pain , decreased appetite, dehydration, dyspnoea, nausea , pyrexia. Topotecan dosage: 2.16MG CYCLIC. During the same period patient was treated with ERLOTINIB, ATIVAN, ANZEMET, ARANESP. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5253103-6
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 28, 2007. Female patient, 57 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chest pain , condition aggravated, decreased appetite, dehydration, diarrhoea, dyspnoea, haematocrit decreased, haemoglobin decreased, heart rate increased. Topotecan dosage: 2.16MG CYCLIC. During the same period patient was treated with ERLOTINIB, ATIVAN, ANZEMET, ARANESP. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5253109-7
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 26, 2007. Female patient, 57 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chest pain , decreased appetite, dehydration, dyspnoea, nausea , pyrexia. Topotecan dosage: 2.16MG CYCLIC. During the same period patient was treated with ERLOTINIB, ATIVAN, ANZEMET, ARANESP. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5286596-9
Topotecan side effect was reported by a Physician from UNITED STATES on Mar 28, 2007. Female patient, 57 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chest pain , decreased appetite, dehydration, diarrhoea, dyspnoea, nausea , pleural effusion, pyrexia. Topotecan dosage: 2.16MG CYCLIC. During the same period patient was treated with ERLOTINIB, ATIVAN, ANZEMET, ARANESP. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5148041-3
Topotecan side effect was reported by a Physician from GERMANY on Nov 06, 2006. Female patient, 53 years of age, weighting 116.8 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood glucose increased, dyspnoea. Topotecan dosage: 6.16MG WEEKLY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5150503-X
Topotecan side effect was reported by a Physician from GERMANY on Nov 08, 2006. Female patient, 53 years of age, weighting 116.8 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: diabetes mellitus inadequate control, dyspnoea, gastrointestinal haemorrhage, shock haemorrhagic. Topotecan dosage: 4MGM2 WEEKLY. During the same period patient was treated with DEXAMETHASONE, CARBOPLATIN, PACLITAXEL, GEMCITABINE. Patient was hospitalized. Patient died on 11/04/2006.


Topotecan Side Effects Report #5150505-3
Topotecan side effect was reported by a Physician from GERMANY on Nov 06, 2006. Female patient, 53 years of age, weighting 116.8 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood glucose increased, dyspnoea. Topotecan dosage: 6.16MG WEEKLY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5157525-3
Topotecan side effect was reported by a Physician from GERMANY on Nov 08, 2006. Female patient, 53 years of age, weighting 116.8 lb, was diagnosed with ovarian cancer, nausea  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: diabetes mellitus inadequate control, disease progression, dyspnoea, gastrointestinal carcinoma, gastrointestinal haemorrhage, shock haemorrhagic. Topotecan dosage: 4MGM2 WEEKLY. During the same period patient was treated with DEXAMETHASONE, CARBOPLATIN, PACLITAXEL, GEMCITABINE. Patient was hospitalized. Patient died on 11/04/2006.

Topotecan Side Effects Report #5453892-1
Topotecan side effect was reported by a Physician from GERMANY on Sept 12, 2007. Female patient, weighting 271.2 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: agitation, dyspnoea, erythema, hypersensitivity. Topotecan dosage: 1.5MG PER DAY. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5463220-3
Topotecan side effect was reported by a Physician from GERMANY on Sept 17, 2007. Female patient, weighting 271.2 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: agitation, dyspnoea, erythema, flushing, hypersensitivity. Topotecan dosage: 1.5MG PER DAY. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5468357-0
Topotecan side effect was reported by a Physician from GERMANY on Sept 20, 2007. Female patient, weighting 271.2 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: agitation, dyspnoea, erythema, flushing, hypersensitivity. Topotecan dosage: 1.5MG PER DAY. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4927882-9
Topotecan side effect was reported by a Physician from GERMANY on Feb 17, 2006. Female patient, weighting 169.8 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: condition aggravated, dyspnoea, pleural effusion. Topotecan dosage: 7.72MG WEEKLY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4742818-1
Topotecan side effect was reported by a Physician from POLAND on Apr 18, 2005. Male patient, 73 years of age, was diagnosed with non-small cell lung cancer, cardiac failure and was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood pressure decreased, dyspnoea, shock. Topotecan dosage: 3.5MGM2 SEE TEXT. During the same period patient was treated with TAXOTERE, DIGOXIN, FUROSEMIDE, SEREVENT, ATROVENT, MORPHINE, LACTULOSE, KETONAL. Patient died on 04/11/2005.

Topotecan Side Effects Report #4821484-0
Topotecan side effect was reported by a Physician from CANADA on Oct 26, 2005. Male patient, 66 years of age, was diagnosed with non-small cell lung cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain lower, abscess intestinal, diverticulum, dyspnoea, intestinal perforation, nausea , peritonitis. Topotecan dosage: 3.5MGM2 CYCLIC. During the same period patient was treated with TAXOTERE, LEVAQUIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4768706-2
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 02, 2005. Female patient, 65 years of age, weighting 170.4 lb, was diagnosed with non-small cell lung cancer, urinary tract infection  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chest pain , chronic obstructive pulmonary disease, dyspnoea, electrocardiogram t wave inversion, gastrointestinal haemorrhage, pancytopenia, urinary tract infection . Topotecan dosage: 1.5MG CYCLIC. During the same period patient was treated with LEVAQUIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5620216-6
Topotecan side effect was reported by a Physician from CANADA on Jan 28, 2008. Female patient, 63 years of age, weighting 162.3 lb, was diagnosed with non-small cell lung cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, dyspnoea, hyperglycaemia, lethargy. Topotecan dosage: unknown. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4976753-0
Topotecan side effect was reported by a Physician from CANADA on Aug 25, 2005. Female patient, 54 years of age, was diagnosed with non-small cell lung cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: cardiovascular disorder, confusional state, depressed level of consciousness, dyspnoea, muscle twitching, oedema peripheral, pyrexia. Topotecan dosage: unknown. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient died on 09/07/2005.

Topotecan Side Effects Report #4988533-0
Topotecan side effect was reported by a Physician from CANADA on Aug 25, 2005. Female patient, 54 years of age, was diagnosed with non-small cell lung cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: cardiovascular disorder, confusional state, depressed level of consciousness, dyspnoea, muscle twitching, oedema peripheral, pneumonia , pyrexia. Topotecan dosage: 3.5MGM2 CYCLIC. During the same period patient was treated with TAXOTERE. Patient was hospitalized. Patient died on 09/07/2005.

Topotecan Side Effects Report #4821280-4
Topotecan side effect was reported by a Health Professional from UNITED STATES on Nov 04, 2005. Female patient, weighting 170.0 lb, was diagnosed with neoplasm recurrence, ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chest pain , chronic obstructive pulmonary disease, dyspnoea, metastases to lung, pleural effusion, restrictive pulmonary disease. Topotecan dosage: 3.32 MG WEEKLY IV. During the same period patient was treated with TOPOTECAN GLAXOSMITHKLINE, LOTENSIN, CALCIUM GLUCONATE, SENNA, ACYCLOVIR, PROVENTIL, ACT AEROSOL, ZOFRAN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5557618-2
Topotecan side effect was reported by a Physician from GERMANY on Dec 06, 2007. Female patient, weighting 183.0 lb, was diagnosed with neoplasm malignant, vomiting and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, pulmonary embolism . Topotecan dosage: 7.6MG WEEKLY. During the same period patient was treated with ZOFRAN, FORTECORTIN. Patient died on 11/28/2007.

Topotecan Side Effects Report #5479643-2
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 02, 2007. Male patient, 45 years of age, was diagnosed with ewing's sarcoma metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: bronchospasm, cough, dehydration, diarrhoea, dyspnoea, hypotension, hypoxia, nausea , pneumonia . Topotecan dosage: 1.8MG CYCLIC. During the same period patient was treated with TARCEVA, ASPIRIN, BUPROPION, DILTIAZEM, FLUTICASONE PROPIONATE, HYDROCODONE, LYRICA, MUCINEX. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5482356-4
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 05, 2007. Male patient, 45 years of age, was diagnosed with ewing's sarcoma metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: bronchospasm, cough, dehydration, diarrhoea, dyspnoea, hypotension, hypoxia, nausea , pneumonia . Topotecan dosage: 1.8MG CYCLIC. During the same period patient was treated with TARCEVA, ASPIRIN, BUPROPION, DILTIAZEM, FLUTICASONE PROPIONATE, HYDROCODONE, LYRICA, MUCINEX. Patient was hospitalized. Patient died on 10/03/2007.

Topotecan Side Effects Report #5835504-8
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 04, 2008. Female patient, 67 years of age, weighting 208.3 lb, was diagnosed with endometrial cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, metastatic uterine cancer, rectal haemorrhage. Topotecan dosage: 3MGM2 CYCLIC. During the same period patient was treated with COUMADIN. Patient was hospitalized. Patient died on 11/13/2005.

Topotecan Side Effects Report #4841308-5
Topotecan side effect was reported by a Physician from UNITED STATES on Nov 09, 2005. Female patient, 67 years of age, weighting 208.3 lb, was diagnosed with endometrial cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, rectal haemorrhage, renal failure. Topotecan dosage: 3MGM2 CYCLIC. During the same period patient was treated with COUMADIN. Patient was hospitalized. Patient died.

Topotecan Side Effects Report #5220861-6
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 23, 2007. Male patient, 64 years of age, weighting 162.3 lb, was diagnosed with colon cancer metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dehydration, dyspnoea, feeling hot and cold, sinus tachycardia. Topotecan dosage: unknown. During the same period patient was treated with ERLOTINIB, PAXIL, PERCOCET, PHENERGAN, ARANESP. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5286590-8
Topotecan side effect was reported by a Physician from UNITED STATES on Mar 28, 2007. Male patient, 64 years of age, weighting 162.3 lb, was diagnosed with colon cancer metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dehydration, dyspnoea, feeling hot and cold, sinus tachycardia. Topotecan dosage: 1MGM2 CYCLIC. During the same period patient was treated with ERLOTINIB, PAXIL, PERCOCET, PHENERGAN, ARANESP. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4967540-8
Topotecan side effect was reported by a Physician from SPAIN on Mar 15, 2006. Female patient, 34 years of age, weighting 116.8 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, erythema, oedema. Topotecan dosage: 3MGM2 SEE TEXT. During the same period patient was treated with PREDNISONE, IBUPROFEN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4882231-X
Topotecan side effect was reported by a Health Professional from UNITED STATES on Jan 13, 2006. Female patient, 79 years of age, weighting 122.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, lung infiltration, radiation pneumonitis. Topotecan dosage: 1.5 MG/M2 X 5 DAYS IV X 4 CYCLES. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4891171-1
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 13, 2006. Female patient, 79 years of age, weighting 122.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, hypoxia, radiation pneumonitis. Topotecan dosage: 1.5MGM2 CYCLIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4893705-X
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 13, 2006. Female patient, 79 years of age, weighting 122.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, hypoxia. Topotecan dosage: 1.5MGM2 CYCLIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4894706-8
Topotecan side effect was reported by a Health Professional from UNITED STATES on Jan 27, 2006. Female patient, 79 years of age, weighting 122.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, chills, dyspnoea, fatigue, hypoxia, lung infiltration. Topotecan dosage: 1.5MG/M2 X 5 DAYS IV 4 CYCLES. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5210677-9
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 15, 2007. Female patient, 78 years of age, weighting 167.3 lb, was diagnosed with hypertension, hypothyroidism, pollakiuria, gastrooesophageal reflux disease, arthritis , nutritional support  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: blood sodium decreased, dehydration, dyspnoea, neutropenia, pyrexia, thrombocytopenia, white blood cell count decreased. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, LOTREL, SYNTHROID, DETROL LA, TOPROL, NEXIUM, MOBIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5227188-7
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 02, 2007. Female patient, 78 years of age, weighting 167.3 lb, was diagnosed with hypertension, hypothyroidism, arthritis , nutritional support  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dehydration, dyspnoea, neutropenia, pyrexia, thrombocytopenia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, LOTREL, SYNTHROID, DETROL LA, TOPROL, NEXIUM, MOBIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5227189-9
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 02, 2007. Female patient, 78 years of age, weighting 167.3 lb, was diagnosed with hypertension, hypothyroidism, arthritis , nutritional support  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dehydration, dyspnoea, neutropenia, pyrexia, thrombocytopenia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, LOTREL, SYNTHROID, DETROL LA, TOPROL, NEXIUM, MOBIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5237746-1
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 12, 2007. Female patient, 78 years of age, weighting 167.3 lb, was diagnosed with hypertension, hypothyroidism, arthritis , nutritional support  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dehydration, dyspnoea, neutropenia, pyrexia, thrombocytopenia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, LOTREL, SYNTHROID, DETROL LA, TOPROL, NEXIUM, MOBIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5421056-3
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 16, 2007. Female patient, 78 years of age, weighting 140.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, arthralgia, dyspnoea, fall , gastrointestinal haemorrhage, haematuria, muscular weakness, platelet count decreased. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, NEULASTA. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5472847-4
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 27, 2007. Female patient, 78 years of age, weighting 140.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, arthralgia, dyspnoea, fall , gastrointestinal haemorrhage, haematuria, muscular weakness. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN, NEULASTA. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5168247-7
Topotecan side effect was reported by a Physician from JAPAN on Dec 07, 2006. Male patient, 76 years of age, was diagnosed with constipation , pain , gastritis, hypertension, insomnia and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, interstitial lung disease, oxygen saturation decreased. Topotecan dosage: 1.61MG PER DAY. During the same period patient was treated with PANTETHINE, MAGNESIUM OXIDE, LOXOPROFEN, TEPRENONE, BROMHEXINE HYDROCHLORIDE, NIFEDIPINE, ETIZOLAM. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5444895-1
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 04, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dyspnoea, tachycardia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5453813-1
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 12, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cardio-respiratory arrest, dyspnoea, tachycardia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 09/05/2007.

Topotecan Side Effects Report #5475788-1
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 02, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cardio-respiratory arrest, dyspnoea, tachycardia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 09/05/2007.

Topotecan Side Effects Report #5506508-X
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 31, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cardio-respiratory arrest, dyspnoea, tachycardia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 09/05/2007.

Topotecan Side Effects Report #5838685-5
Topotecan side effect was reported by a Physician from HUNGARY on Aug 03, 2008. Female patient, 72 years of age, weighting 119.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, bronchial secretion retention, dyspnoea, febrile neutropenia, pulmonary thrombosis, thrombocytopenia. Topotecan dosage: 1.75MG PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient died on 08/02/2008.

Topotecan Side Effects Report #5865092-1
Topotecan side effect was reported by a Physician from HUNGARY on Aug 22, 2008. Female patient, 72 years of age, weighting 119.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, bronchial obstruction, bronchial secretion retention, dyspnoea, febrile neutropenia, pulmonary thrombosis, respiratory tract haemorrhage, respiratory tract infection. Topotecan dosage: 1.75MG PER DAY. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient died on 08/02/2008.

Topotecan Side Effects Report #4945464-X
Topotecan side effect was reported by a Physician from JAPAN on Feb 24, 2006. Male patient, 70 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, interstitial lung disease, neutrophil count decreased, pneumocystis jiroveci pneumonia, pyrexia. Topotecan dosage: 1.1MG PER DAY. During the same period patient was treated with CEFEPIME DIHYDROCHLORIDE, REBAMIPIDE, MAGNESIUM OXIDE, BETAMETASONE, ISOSORBIDE. Patient died on 03/03/2006.

Topotecan Side Effects Report #5934191-8
Topotecan side effect was reported by a Physician from GERMANY on Oct 27, 2008. Female patient, 67 years of age, weighting 160.9 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dizziness , dyspnoea. Topotecan dosage: 1.305MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5951823-9
Topotecan side effect was reported by a Physician from GERMANY on Nov 10, 2008. Female patient, 67 years of age, weighting 160.9 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dizziness , dyspnoea. Topotecan dosage: 1.305MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5955053-6
Topotecan side effect was reported by a Physician from GERMANY on Nov 14, 2008. Female patient, 67 years of age, weighting 165.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dizziness , dyspnoea, haemoglobin. Topotecan dosage: 1.305MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5968723-0
Topotecan side effect was reported by a Physician from GERMANY on Nov 18, 2008. Female patient, 67 years of age, weighting 165.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dizziness , dyspnoea, haemoglobin. Topotecan dosage: 1.305MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5046443-7
Topotecan side effect was reported by a Physician from GERMANY on Apr 10, 2006. Male patient, 65 years of age, was diagnosed with supraventricular tachycardia and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, embolism, pain in extremity, peripheral coldness, pulmonary embolism . Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, BELOC ZOK. Patient recovered.

Topotecan Side Effects Report #5013625-X
Topotecan side effect was reported by a Physician from GERMANY on Apr 10, 2006. Male patient, 65 years of age, was diagnosed with supraventricular tachycardia and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, embolism, pain in extremity, peripheral coldness, pulmonary embolism . Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, BELOC ZOK. Patient recovered.

Topotecan Side Effects Report #5574931-3
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 21, 2007. Male patient, 61 years of age, was diagnosed with blood pressure , nausea , pain  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, blood potassium decreased, blood sodium decreased, cardiac failure congestive, dyspnoea, fatigue, fluid overload, haematemesis, left ventricular hypertrophy. Topotecan dosage: 7.5MG WEEKLY. During the same period patient was treated with HYDROCORTISONE, FLUDROCORTISONE ACETATE, METOCLOPRAMIDE, HYDROMORPHONE, ARANESP, MAGNESIUM OXIDE, FENTANYL, ZOCOR. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5959835-6
Topotecan side effect was reported by a Consumer or non-health professional from KOREA, REPUBLIC OF on Nov 10, 2008. Male patient, 58 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, dyspnoea, haematocrit decreased, heart rate increased, hypotension, hypoxia, lung neoplasm, metabolic acidosis, pulmonary toxicity. Topotecan dosage: 1.5MGM2 PER DAY. During the same period patient was treated with FOLINIC ACID, FLUOROURACIL, IRINOTECAN HYDROCHLORIDE, PREDNISOLONE. Patient died.

Topotecan Side Effects Report #5006595-1
Topotecan side effect was reported by a Physician from UNITED STATES on May 15, 2006. Male patient, 57 years of age, weighting 176.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: atrioventricular block complete, cardiac arrest , cardio-respiratory arrest, conduction disorder, dyspnoea. Topotecan dosage: 3MGM2 WEEKLY. During the same period patient was treated with VELCADE. Patient died on 05/06/2006.

Topotecan Side Effects Report #4954104-5
Topotecan side effect was reported by a Physician from SPAIN on Mar 15, 2006. Female patient, 34 years of age, weighting 116.8 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, erythema, oedema. Topotecan dosage: 3MGM2 SEE TEXT. During the same period patient was treated with PREDNISONE, IBUPROFEN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5181066-0
Topotecan side effect was reported by a Health Professional from UNITED STATES on Dec 18, 2006. Male patient, weighting 150.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, heart rate increased, lymphadenopathy, malaise, pleural effusion, pulmonary mass, tachypnoea. Topotecan dosage: 3MG/M2 D 1, 8, 15 Q28 IV. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5532059-2
Topotecan side effect was reported by a Physician from GERMANY on Nov 29, 2007. Female patient, weighting 183.0 lb, was diagnosed with vomiting and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, pulmonary embolism . Topotecan dosage: 7.6MG WEEKLY. During the same period patient was treated with ZOFRAN, FORTECORTIN. Patient died on 11/28/2007.

Topotecan Side Effects Report #5537399-9
Topotecan side effect was reported by a Physician from GERMANY on Nov 30, 2007. Female patient, weighting 183.0 lb, was diagnosed with vomiting and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, pulmonary embolism . Topotecan dosage: 7.6MG WEEKLY. During the same period patient was treated with ZOFRAN, FORTECORTIN. Patient died on 11/28/2007.

Topotecan Side Effects Report #5566806-0
Topotecan side effect was reported by a Physician from GERMANY on Dec 13, 2007. Female patient, weighting 183.0 lb, was diagnosed with vomiting and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, pulmonary embolism . Topotecan dosage: 7.6MG WEEKLY. During the same period patient was treated with ZOFRAN, FORTECORTIN. Patient died on 11/28/2007.

Topotecan Side Effects Report #5739175-0
Topotecan side effect was reported by a Physician from GERMANY on May 14, 2008. Female patient was diagnosed with pain  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: ascites, dyspnoea, pain . Topotecan dosage: 4MG WEEKLY. During the same period patient was treated with ALBUMIN, TRAMAL LONG, HALOPERIDOL, NOVALDIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5759771-4
Topotecan side effect was reported by a Physician from GERMANY on May 26, 2008. Female patient was diagnosed with pain  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: ascites, dyspnoea, pain . Topotecan dosage: 4MG WEEKLY. During the same period patient was treated with ALBUMIN, TRAMAL LONG, HALOPERIDOL, NOVALDIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5759789-1
Topotecan side effect was reported by a Physician from GERMANY on May 29, 2008. Female patient, weighting 153.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaphylactic shock, blood pressure immeasurable, circulatory collapse, convulsion, depressed level of consciousness, dyspnoea, muscle spasms. Topotecan dosage: 1.3MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient recovered.

Topotecan Side Effects Report #5787931-5
Topotecan side effect was reported by a Physician from GERMANY on June 19, 2008. Female patient, weighting 153.2 lb, was diagnosed with hypertension and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaphylactic shock, blood pressure immeasurable, circulatory collapse, convulsion, depressed level of consciousness, dyspnoea, flushing, infusion related reaction, muscle spasms. Topotecan dosage: 1.3MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN, BISOPROLOL FUMARATE, RAMIPRIL. Patient recovered.

Topotecan Side Effects Report #5787933-9
Topotecan side effect was reported by a Physician from GERMANY on June 23, 2008. Female patient, weighting 131.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaphylactic reaction, dyspnoea, rash . Topotecan dosage: 1.25MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5803299-X
Topotecan side effect was reported by a Physician from GERMANY on July 04, 2008. Female patient, weighting 153.2 lb, was diagnosed with hypertension and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaphylactic shock, blood pressure immeasurable, circulatory collapse, convulsion, depressed level of consciousness, dyspnoea, flushing, infusion related reaction, muscle spasms. Topotecan dosage: 1.3MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN, BISOPROLOL FUMARATE, RAMIPRIL. Patient recovered.

Topotecan Side Effects Report #5815022-3
Topotecan side effect was reported by a Physician from GERMANY on July 14, 2008. Female patient, weighting 131.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaphylactic reaction, dyspnoea, rash . Topotecan dosage: 1.25MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5824471-9
Topotecan side effect was reported by a Physician from GERMANY on July 25, 2008. Female patient, weighting 284.4 lb, was diagnosed with hypertension, atrial fibrillation  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, cardiac failure, dyspnoea, renal failure, tachyarrhythmia. Topotecan dosage: 1.58MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN, TOREM, BISOPROLOL FUMARATE, LANITOP, SPIRONOLACTONE, MARCUMAR. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5932805-X
Topotecan side effect was reported by a Physician from GERMANY on Oct 22, 2008. Female patient, weighting 202.8 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, flushing. Topotecan dosage: unknown. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5937472-7
Topotecan side effect was reported by a Physician from GERMANY on Oct 30, 2008. Female patient, weighting 202.8 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: dyspnoea, flushing. Topotecan dosage: 1.46MG CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #6115052-0
Topotecan side effect was reported by a Physician from GERMANY on Mar 10, 2009. Female patient, weighting 284.4 lb, was diagnosed with hypertension, atrial fibrillation  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, cardiac failure, dyspnoea, haemoglobin abnormal, platelet count abnormal, renal failure, tachyarrhythmia. Topotecan dosage: 1.58MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN, TORSEMIDE, CONCOR, LANITOP, SPIRONOLACTONE, MARCUMAR. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #6133669-4
Topotecan side effect was reported by a Physician from GERMANY on Mar 19, 2009. Female patient, weighting 284.4 lb, was diagnosed with hypertension, atrial fibrillation  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, cardiac failure, dyspnoea, haemoglobin abnormal, platelet count abnormal, renal failure, tachyarrhythmia. Topotecan dosage: 1.58MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN, TOREM, BISOPROLOL FUMARATE, LANITOP, SPIRONOLACTONE, MARCUMAR. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4633863-5
Topotecan side effect was reported by a Consumer or non-health professional from on Apr 12, 2005. Female patient, weighting 106.9 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, dyspnoea, echocardiogram abnormal, mediastinal mass, tachyarrhythmia. Topotecan dosage: unknown. During the same period patient was treated with ETOPOSIDE, CISPLATIN, IRINOTECAN. Patient recovered.