Topotecan and diarrhoea Patient Reports February 11, 2012

Topotecan Side Effects Report #4597339-6
Topotecan side effect was reported by a Health Professional from on Feb 28, 2005. Female patient, weighting 125.0 lb, was diagnosed with small cell lung cancer extensive stage and was treated with Topotecan. After drug was administered, patient experienced the following side effects: diarrhoea, nausea , neutropenia. Topotecan dosage: 3 MG/ DAY ORAL. During the same period patient was treated with CARBOPLATIN, OXYCODONE, HYDROCODONE BITARTRATE, PROMETHAZINE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5819155-7
Topotecan side effect was reported by a Physician from UNITED STATES on July 15, 2008. Female patient, 65 years of age, weighting 155.9 lb, was diagnosed with ovarian cancer recurrent and was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain , anaemia, diarrhoea, disease progression, gastrooesophageal reflux disease, haematemesis, nausea , upper gastrointestinal haemorrhage. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with BEVACIZUMAB, FEXOFENADINE, METHYLCELLULOSE, EQUITAM, OMEPRAZOLE, ESOMEPRAZOLE MAGNESIUM, TYLENOL PM. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5822958-6
Topotecan side effect was reported by a Physician from UNITED STATES on July 18, 2008. Female patient, 65 years of age, weighting 155.9 lb, was diagnosed with ovarian cancer recurrent and was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain , anaemia, diarrhoea, disease progression, gastrooesophageal reflux disease, haematemesis, nausea , upper gastrointestinal haemorrhage. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with BEVACIZUMAB, FEXOFENADINE, METHYLCELLULOSE, EQUITAM, OMEPRAZOLE, ESOMEPRAZOLE, TYLENOL PM. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5518298-5
Topotecan side effect was reported by a Health Professional from UNITED STATES on Nov 13, 2007. Female patient, weighting 137.8 lb, was diagnosed with ovarian cancer metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal mass, anaemia, anorexia, condition aggravated, depression , diarrhoea, disease progression, nausea , pelvic mass. Topotecan dosage: 3 MG/M2 D1,8,15 Q 21 D IV. During the same period patient was treated with VELCADE. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5628665-7
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 14, 2008. Female patient, 76 years of age, weighting 155.9 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain , diarrhoea, nausea . Topotecan dosage: 6.96MG WEEKLY IV. During the same period patient was treated with BEVACIZUMAB. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4742817-X
Topotecan side effect was reported by a Physician from SOUTH AFRICA on Aug 08, 2005. Female patient, 67 years of age, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, nausea , syncope, urinary tract infection . Topotecan dosage: 1.25MGM2 PER DAY. During the same period patient was treated with CIPROFLOXACIN, IMODIUM, PROCHLOROPERAZINE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5253103-6
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 28, 2007. Female patient, 57 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chest pain , condition aggravated, decreased appetite, dehydration, diarrhoea, dyspnoea, haematocrit decreased, haemoglobin decreased, heart rate increased. Topotecan dosage: 2.16MG CYCLIC. During the same period patient was treated with ERLOTINIB, ATIVAN, ANZEMET, ARANESP. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5286596-9
Topotecan side effect was reported by a Physician from UNITED STATES on Mar 28, 2007. Female patient, 57 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chest pain , decreased appetite, dehydration, diarrhoea, dyspnoea, nausea , pleural effusion, pyrexia. Topotecan dosage: 2.16MG CYCLIC. During the same period patient was treated with ERLOTINIB, ATIVAN, ANZEMET, ARANESP. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4599691-4
Topotecan side effect was reported by a Physician from on Feb 18, 2005. Male patient, 65 years of age, weighting 152.1 lb, was diagnosed with non-small cell lung cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, neutropenia, thrombocytopenia. Topotecan dosage: 3.5MGM2 PER DAY. During the same period patient was treated with TAXOTERE, DEXAMETHASONE, THEOVENT. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5849527-6
Topotecan side effect was reported by a Physician from GERMANY on Aug 14, 2008. Female patient, weighting 132.3 lb, was diagnosed with neoplasm malignant and was treated with Topotecan. After drug was administered, patient experienced the following side effects: c-reactive protein increased, dehydration, diarrhoea, infection , pyrexia, thrombocytopenia. Topotecan dosage: 1.3MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4794278-2
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 29, 2005. Female patient was diagnosed with neoplasm malignant and was treated with Topotecan. After drug was administered, patient experienced the following side effects: diarrhoea, nausea , neutropenia, renal failure, sepsis . Topotecan dosage: .4MGM2 PER DAY. During the same period patient was treated with DOXIL. Patient recovered.

Topotecan Side Effects Report #6017980-3
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 19, 2008. Male patient, 70 years of age, weighting 159.8 lb, was diagnosed with neoplasm and was treated with Topotecan. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, hypotension, nausea . Topotecan dosage: 2.3MGM2 PER DAY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #6032972-6
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 30, 2008. Male patient, 70 years of age, weighting 159.8 lb, was diagnosed with neoplasm and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, decreased appetite, dehydration, diarrhoea, dizziness , eating disorder , hypotension, nausea . Topotecan dosage: 2.3MGM2 PER DAY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5479643-2
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 02, 2007. Male patient, 45 years of age, was diagnosed with ewing's sarcoma metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: bronchospasm, cough, dehydration, diarrhoea, dyspnoea, hypotension, hypoxia, nausea , pneumonia . Topotecan dosage: 1.8MG CYCLIC. During the same period patient was treated with TARCEVA, ASPIRIN, BUPROPION, DILTIAZEM, FLUTICASONE PROPIONATE, HYDROCODONE, LYRICA, MUCINEX. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5482356-4
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 05, 2007. Male patient, 45 years of age, was diagnosed with ewing's sarcoma metastatic and was treated with Topotecan. After drug was administered, patient experienced the following side effects: bronchospasm, cough, dehydration, diarrhoea, dyspnoea, hypotension, hypoxia, nausea , pneumonia . Topotecan dosage: 1.8MG CYCLIC. During the same period patient was treated with TARCEVA, ASPIRIN, BUPROPION, DILTIAZEM, FLUTICASONE PROPIONATE, HYDROCODONE, LYRICA, MUCINEX. Patient was hospitalized. Patient died on 10/03/2007.

Topotecan Side Effects Report #4853285-1
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 06, 2005. Female patient, 48 years of age, weighting 220.5 lb, was diagnosed with cervix carcinoma recurrent and was treated with Topotecan. After drug was administered, patient experienced the following side effects: clostridial infection, culture stool positive, diarrhoea, nausea . Topotecan dosage: 1.5MG PER DAY. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5115266-2
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 28, 2006. Female patient, 54 years of age, weighting 97.00 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: diarrhoea, eating disorder , hyperkalaemia, hyponatraemia, nausea , neutropenia, pancytopenia, sepsis . Topotecan dosage: 2MGM2 WEEKLY. During the same period patient was treated with CISPLATIN, FENTANYL, DARVOCET, LOMOTIL, BACTRIM DS. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5094334-8
Topotecan side effect was reported by a Health Professional from UNITED STATES on Aug 30, 2006. Female patient, weighting 97.00 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: diarrhoea, hyperkalaemia, hyponatraemia, nausea . Topotecan dosage: 2 MG/M2 WKLY IV. During the same period patient was treated with CISPLATIN, FENTANYL, DARVOCET, LOMOTIL, BACTRIM DS. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4774446-6
Topotecan side effect was reported by a Health Professional from UNITED STATES on Sept 19, 2005. Female patient, weighting 128.0 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, diarrhoea, escherichia urinary tract infection, pyelonephritis. Topotecan dosage: 0.62 MG DAILY X 14D IV. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4916835-2
Topotecan side effect was reported by a Health Professional from UNITED STATES on Feb 16, 2006. Female patient, weighting 158.7 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: chills, cold sweat, constipation , decreased appetite, diarrhoea, dysuria, febrile neutropenia, haemorrhoids, micturition urgency. Topotecan dosage: 2 MG/M2 IV. During the same period patient was treated with CISPLATIN, MYSTATIN CREASM, LOMOTIL DIPHENOXYLATE AND ATROPINE SULPHATELET, COMPAZINE, ACETAMINOPHEN, DIBUCAINE OINT, AQUAPHOR HYDROPHILILIC PETROLATUM OINT, PYRIDIUM PHENAZOPYRIDINE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5618470-X
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 01, 2008. Male patient, 79 years of age, weighting 118.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain upper, asthenia, dehydration, diarrhoea, hypotension, neutropenia, syncope, thrombocytopenia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4744832-9
Topotecan side effect was reported by a Physician from GERMANY on Apr 21, 2004. Male patient, 75 years of age, weighting 132.3 lb, was diagnosed with sleep disorder  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, blood creatine increased, blood potassium increased, bone marrow depression, diarrhoea, inflammation, klebsiella infection. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CARBOPLATIN, XIMOVAN. Patient was hospitalized. Patient died on 03/13/2004.

Topotecan Side Effects Report #4554299-1
Topotecan side effect was reported by a Physician from on Jan 03, 2005. Male patient, 73 years of age, weighting 202.8 lb, was diagnosed with bone pain, prophylaxis and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anorexia, blood creatinine increased, blood potassium decreased, dehydration, diarrhoea, enterocolitis viral, hepatic enzyme increased, neutropenia. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, DICLOFENAC, CIPROFLOXACIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4645203-6
Topotecan side effect was reported by a Physician from on Apr 19, 2005. Female patient, 67 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal distension, abdominal pain upper, alopecia, back pain , chest pain , constipation , diarrhoea, dysgeusia, dyspepsia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with INSULIN, SYNTHROID, ALUMINUM HYDROXIDE AND MAGNESIUM TRISILICATE, METOPROLOL TARTRATE, ASPIRIN, NITROGLYCERIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4850895-2
Topotecan side effect was reported by a Physician from GERMANY on Nov 29, 2005. Female patient, 66 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: diarrhoea, dizziness , hypotension. Topotecan dosage: unknown. During the same period patient was treated with CISPLATIN, PRESOMEN, CIPRAMIL, STANGYL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #6041624-8
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 16, 2009. Female patient, 64 years of age, weighting 192.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: diarrhoea. Topotecan dosage: 4.5MG CYCLIC. During the same period patient was treated with BEVACIZUMAB. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4686261-2
Topotecan side effect was reported by a Physician from on May 30, 2005. Male patient, 59 years of age, weighting 172.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: angina pectoris, cardiac disorder, diarrhoea, hypovolaemia, vomiting. Topotecan dosage: unknown. During the same period patient was treated with CISPLATIN, CONCOR, DIPYRONE, PANTOPRAZOLE, ENALAPRIL MALEATE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4696020-2
Topotecan side effect was reported by a Physician from on May 30, 2005. Male patient, 59 years of age, weighting 172.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: angina pectoris, cardiac disorder, diarrhoea, hypovolaemia, vomiting. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, CONCOR, DIPYRONE, METOCLOPRAMIDE HYDROCHLORIDE, PANTOPRAZOLE, ENALAPRIL MALEATE, CEFOTIAM HYDROCHLORIDE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4773822-5
Topotecan side effect was reported by a Physician from GERMANY on May 30, 2005. Male patient, 59 years of age, weighting 172.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: angina pectoris, cardiac disorder, diarrhoea, hypovolaemia, pancreatitis necrotising, vomiting. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, CONCOR, NOVALGIN, PASPERTIN, PANTOZOL, ENALAPRIL, CEFOTIAM HYDROCHLORIDE. Patient was hospitalized. Patient died on 08/17/2005.


Topotecan Side Effects Report #4785569-X
Topotecan side effect was reported by a Physician from GERMANY on May 30, 2005. Male patient, 59 years of age, weighting 172.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: angina pectoris, blood potassium decreased, cardiac disorder, diarrhoea, haemoglobin decreased, hypovolaemia, pancreatitis, vomiting. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, CONCOR, NOVALGIN, PASPERTIN, PANTOZOL, ENALAPRIL, CEFOTIAM HYDROCHLORIDE. Patient was hospitalized. Patient died on 08/17/2005.

Topotecan Side Effects Report #5095974-2
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 28, 2006. Female patient, 54 years of age, weighting 97.00 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: diarrhoea, eating disorder , hyperkalaemia, hyponatraemia, nausea . Topotecan dosage: 2MGM2 WEEKLY. During the same period patient was treated with CISPLATIN, FENTANYL, DARVOCET, LOMOTIL, BACTRIM DS. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5098742-0
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 28, 2006. Female patient, 54 years of age, weighting 97.00 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: diarrhoea, eating disorder , hyperkalaemia, hyponatraemia, nausea , sepsis . Topotecan dosage: 2MGM2 WEEKLY. During the same period patient was treated with CISPLATIN, FENTANYL, DARVOCET, LOMOTIL, BACTRIM DS. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5313388-4
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 27, 2007. Female patient, weighting 155.9 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal distension, anaemia, blood alkaline phosphatase increased, diarrhoea, nausea , pain , thrombocytopenia. Topotecan dosage: 8.9 MG. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5409431-4
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 07, 2007. Female patient, weighting 134.1 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain lower, culture urine positive, diarrhoea, flank pain, ill-defined disorder, trichosporon infection. Topotecan dosage: 15.9 MG. During the same period patient was treated with CIPRO, FENTANYL, LOVENOX, NICODERM, PERCOCET, PHENERGAN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5409691-X
Topotecan side effect was reported by a Health Professional from UNITED STATES on Aug 08, 2007. Female patient, weighting 134.1 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: bacteria urine identified, diarrhoea, flank pain, frequent bowel movements, trichosporon infection. Topotecan dosage: unknown. During the same period patient was treated with LOVENOX, CIPRO, FENTANYL, FLAGYL, NICODERM, PERCOCET, PHENERGAN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5836860-7
Topotecan side effect was reported by a Physician from GERMANY on July 31, 2008. Female patient, weighting 132.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: c-reactive protein increased, dehydration, diarrhoea, infection , thrombocytopenia. Topotecan dosage: 1.3MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5862974-1
Topotecan side effect was reported by a Physician from GERMANY on Aug 22, 2008. Female patient, weighting 132.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: c-reactive protein increased, dehydration, diarrhoea, infection , pyrexia, thrombocytopenia. Topotecan dosage: 1.3MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5978586-5
Topotecan side effect was reported by a Physician from GERMANY on Dec 02, 2008. Female patient, weighting 132.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: c-reactive protein increased, dehydration, diarrhoea, infection , platelet count, pyrexia, thrombocytopenia. Topotecan dosage: 1.3MG CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #6003543-2
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 12, 2008. Female patient, weighting 240.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain , back pain , blood glucose increased, diarrhoea, dyspnoea exertional, faecal incontinence, hypokalaemia, melaena, nausea . Topotecan dosage: 24 MG. Patient was hospitalized. Patient recovered.