Topotecan and asthenia Patient Reports February 11, 2012

Topotecan Side Effects Report #5975846-9
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 02, 2008. Female patient, 60 years of age, weighting 160.1 lb, was diagnosed with ovarian cancer recurrent and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cough, dizziness , dyspnoea, fatigue, pleural effusion, pneumonitis. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with BEVACIZUMAB, LEVOFLOXACIN, FEXOFENADINE, LORAZEPAM, DEXAMETHASONE, PRILOSEC, SUDAFED, TYLENOL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4728740-5
Topotecan side effect was reported by a Physician from CANADA on July 25, 2005. Female patient, 71 years of age, weighting 160.3 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, fatigue, intestinal perforation, neutropenia, pyrexia, sepsis , urinary tract infection . Topotecan dosage: .75MGM2 CYCLIC. During the same period patient was treated with CISPLATIN. Patient was hospitalized. Patient died on 07/21/2005.

Topotecan Side Effects Report #4753832-4
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 23, 2005. Female patient, 64 years of age, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, ear discomfort, febrile neutropenia, pancytopenia, pharyngolaryngeal pain. Topotecan dosage: unknown. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4773801-8
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 23, 2005. Female patient, 64 years of age, weighting 174.4 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, dysphonia, ear discomfort, febrile neutropenia, flatulence, hypomagnesaemia, nasopharyngitis, pancytopenia, pharyngolaryngeal pain. Topotecan dosage: 2.2MG SEE TEXT. During the same period patient was treated with THALIDOMIDE, TENORMIN, ASPIRIN, MAGNESIUM, AMILORIDE. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5219159-1
Topotecan side effect was reported by a Physician from GERMANY on Jan 19, 2007. Female patient, 59 years of age, weighting 141.1 lb, was diagnosed with ovarian cancer and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, condition aggravated, fatigue, feeling abnormal, ileus. Topotecan dosage: 6.92MG WEEKLY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #6032972-6
Topotecan side effect was reported by a Physician from UNITED STATES on Dec 30, 2008. Male patient, 70 years of age, weighting 159.8 lb, was diagnosed with neoplasm and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, decreased appetite, dehydration, diarrhoea, dizziness , eating disorder , hypotension, nausea . Topotecan dosage: 2.3MGM2 PER DAY. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5853904-7
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 15, 2008. Male patient, 66 years of age, weighting 180.3 lb, was diagnosed with glioblastoma multiforme and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, cognitive disorder, feeling abnormal, mental status changes. Topotecan dosage: .2MLH CONTINUOUS. During the same period patient was treated with ZOLOFT, DAPSONE, COZAAR, SPIRIVA, KEPPRA, ADVAIR DISKUS, DEXAMETHASONE, DIAZEPAM. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5867005-5
Topotecan side effect was reported by a Physician from UNITED STATES on Aug 27, 2008. Male patient, 66 years of age, weighting 180.3 lb, was diagnosed with glioblastoma multiforme and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, cognitive disorder, feeling abnormal, gait disturbance, mental status changes. Topotecan dosage: .2MLH CONTINUOUS. During the same period patient was treated with ZOLOFT, DAPSONE, COZAAR, SPIRIVA, KEPPRA, ADVAIR DISKUS, DEXAMETHASONE, DIAZEPAM. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4685362-2
Topotecan side effect was reported by a Physician from on June 02, 2005. Female patient, 69 years of age, weighting 131.6 lb, was diagnosed with endometrial cancer stage iv and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dehydration, disease progression, nausea , rectal haemorrhage. Topotecan dosage: 3.5MGM2 CYCLIC. During the same period patient was treated with TAXOTERE, FENTANYL, VICODIN, REGLAN, ARANESP, COMPAZINE, MORPHINE. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #4821271-3
Topotecan side effect was reported by a Health Professional from UNITED STATES on Nov 04, 2005. Female patient, 23 years of age, weighting 153.7 lb, was diagnosed with cervix carcinoma stage ii and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, back pain , blood creatinine increased, fatigue, hydronephrosis, respiratory rate increased. Topotecan dosage: 0.15 MG/M2 CONT IV. During the same period patient was treated with CISPLATIN, BENADRYL, PERCOCET. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5530651-2
Topotecan side effect was reported by a Physician from GERMANY on Nov 23, 2007. Female patient, 30 years of age, weighting 121.3 lb, was diagnosed with cervix carcinoma and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, fatigue, malnutrition. Topotecan dosage: 2.9MG WEEKLY. During the same period patient was treated with PACLITAXEL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5587010-6
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 08, 2008. Male patient, 79 years of age, weighting 119.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, anorexia, asthenia, dehydration, neutropenia, orthostatic hypotension, pyrexia. Topotecan dosage: 6.5MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5618470-X
Topotecan side effect was reported by a Physician from UNITED STATES on Feb 01, 2008. Male patient, 79 years of age, weighting 118.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain upper, asthenia, dehydration, diarrhoea, hypotension, neutropenia, syncope, thrombocytopenia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5700287-9
Topotecan side effect was reported by a Physician from UNITED STATES on Apr 08, 2008. Male patient, 79 years of age, weighting 119.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, anorexia, asthenia, dehydration, neutropenia, orthostatic hypotension, pyrexia. Topotecan dosage: 6.5MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5712828-6
Topotecan side effect was reported by a Physician from UNITED STATES on Apr 21, 2008. Male patient, 79 years of age, weighting 119.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, anorexia, asthenia, dehydration, neutropenia, orthostatic hypotension, platelet count decreased, pyrexia, white blood cell count decreased. Topotecan dosage: 6.5MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5571725-X
Topotecan side effect was reported by a Physician from POLAND on Dec 18, 2007. Male patient, 75 years of age, weighting 143.3 lb, was diagnosed with infection prophylaxis, oral candidiasis and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, leukopenia, oral candidiasis, platelet count decreased. Topotecan dosage: unknown. During the same period patient was treated with RADIATION, DEXAVEN, CYCLONAMINE, AUGMENTIN, MICONAZOLE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5588685-8
Topotecan side effect was reported by a Physician from POLAND on Jan 06, 2008. Male patient, 75 years of age, weighting 143.3 lb, was diagnosed with infection prophylaxis, oral candidiasis and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, disease progression, leukopenia, oral candidiasis, platelet count decreased. Topotecan dosage: 1.1MGM2 PER DAY. During the same period patient was treated with RADIATION, DEXAVEN, CYCLONAMINE, AUGMENTIN, MICONAZOLE. Patient was hospitalized. Patient died on 01/02/2007.

Topotecan Side Effects Report #5208979-5
Topotecan side effect was reported by a Physician from GERMANY on Jan 12, 2007. Male patient, 74 years of age, weighting 187.4 lb, was diagnosed with hypertension and was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, c-reactive protein increased, cough, haemoglobin decreased, hypokalaemia, nausea , platelet count decreased, productive cough. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, FENTANYL TRANSDERMAL SYSTEM, CAPTOPRIL, PRAVASTATIN, THEOPHYLLINE, ALLOPURINOL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5040418-X
Topotecan side effect was reported by a Physician from GERMANY on June 21, 2006. Male patient, 74 years of age, weighting 187.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, cough, productive cough, pyrexia. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, FENTANYL TRANSDERMAL SYSTEM, CAPTOPRIL, PRAVASTATIN, THEOPHYLLINE, ALLOPURINOL. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5444895-1
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 04, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dyspnoea, tachycardia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5453813-1
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 12, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cardio-respiratory arrest, dyspnoea, tachycardia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 09/05/2007.

Topotecan Side Effects Report #5474746-0
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 27, 2007. Female patient, 72 years of age, weighting 101.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abdominal pain , asthenia, back pain , dehydration, hyponatraemia, nausea , pneumonia . Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5475788-1
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 02, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cardio-respiratory arrest, dyspnoea, tachycardia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 09/05/2007.

Topotecan Side Effects Report #5506508-X
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 31, 2007. Female patient, 72 years of age, weighting 92.15 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, cardio-respiratory arrest, dyspnoea, tachycardia. Topotecan dosage: 4MGM2 CYCLIC. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient died on 09/05/2007.


Topotecan Side Effects Report #6128309-4
Topotecan side effect was reported by a Physician from UNITED STATES on Mar 20, 2009. Female patient, 69 years of age, weighting 213.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: accidental overdose, anaemia, asthenia, condition aggravated, confusional state, fall , leukopenia, lung cancer metastatic, sepsis . Topotecan dosage: 2.3MGM2 PER DAY. During the same period patient was treated with RADIATION, STEROID. Patient was hospitalized. Patient died on 03/08/2009.

Topotecan Side Effects Report #5934191-8
Topotecan side effect was reported by a Physician from GERMANY on Oct 27, 2008. Female patient, 67 years of age, weighting 160.9 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dizziness , dyspnoea. Topotecan dosage: 1.305MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5951823-9
Topotecan side effect was reported by a Physician from GERMANY on Nov 10, 2008. Female patient, 67 years of age, weighting 160.9 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dizziness , dyspnoea. Topotecan dosage: 1.305MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5955053-6
Topotecan side effect was reported by a Physician from GERMANY on Nov 14, 2008. Female patient, 67 years of age, weighting 165.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dizziness , dyspnoea, haemoglobin. Topotecan dosage: 1.305MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5968723-0
Topotecan side effect was reported by a Physician from GERMANY on Nov 18, 2008. Female patient, 67 years of age, weighting 165.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, dizziness , dyspnoea, haemoglobin. Topotecan dosage: 1.305MG THREE TIMES PER WEEK. During the same period patient was treated with CARBOPLATIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5472860-7
Topotecan side effect was reported by a Physician from UNITED STATES on Sept 26, 2007. Male patient, 66 years of age, weighting 135.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, anorexia, asthenia, dehydration, dysgeusia, ill-defined disorder. Topotecan dosage: 3MGM2 CYCLIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5506511-X
Topotecan side effect was reported by a Physician from UNITED STATES on Oct 30, 2007. Male patient, 66 years of age, weighting 135.4 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, anorexia, asthenia, dehydration, dysgeusia, ill-defined disorder. Topotecan dosage: 3MGM2 CYCLIC. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4697159-8
Topotecan side effect was reported by a Health Professional from on June 21, 2005. Female patient, 64 years of age, weighting 171.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, ear discomfort, febrile neutropenia, increased upper airway secretion, pancytopenia, pharyngolaryngeal pain. Topotecan dosage: 1.25 MG/M2 D1-5 IV. During the same period patient was treated with TENORMIN, ASPIRIN, THALIDOMIDE, MAGNESIUM, AMILORIDE. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #4630551-6
Topotecan side effect was reported by a Physician from on Apr 05, 2005. Female patient, 55 years of age, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, cardiopulmonary failure, ill-defined disorder, septic shock, stomatitis. Topotecan dosage: 1MGM2 PER DAY. During the same period patient was treated with CISPLATIN, BETAISODONA, TRAMADOL, KLACID, PASPERTIN DROPS, NAVOBAN, DULCOLAX, CONCOR. Patient died on 04/01/2005.

Topotecan Side Effects Report #4917395-2
Topotecan side effect was reported by a Physician from GERMANY on Feb 09, 2006. Female patient, 47 years of age, weighting 72.75 lb, was diagnosed with prophylaxis and was treated with Topotecan. After drug was administered, patient experienced the following side effects: anaemia, asthenia, bronchitis , dehydration, depressed level of consciousness, hyponatraemia, pyrexia, sepsis , sputum purulent. Topotecan dosage: 11.3MG CUMULATIVE DOSE. During the same period patient was treated with CISPLATIN, SULTANOL, ATROVENT, LASIX, TAZOBAC, ENOXAPARIN, VERGENTAN, FORTECORTIN. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5563146-0
Topotecan side effect was reported by a Physician from GERMANY on Dec 07, 2007. Female patient, 30 years of age, weighting 121.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, fatigue, malnutrition. Topotecan dosage: 2.9MG WEEKLY. During the same period patient was treated with PACLITAXEL. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5648676-5
Topotecan side effect was reported by a Physician from GERMANY on Feb 28, 2008. Female patient, 30 years of age, weighting 121.3 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, fatigue, malnutrition. Topotecan dosage: 2.9MG WEEKLY. During the same period patient was treated with PACLITAXEL, EPOGEN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5283006-2
Topotecan side effect was reported by a Health Professional from UNITED STATES on Mar 29, 2007. Female patient, weighting 102.0 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, balance disorder, disease progression, platelet count decreased. Topotecan dosage: 3MG/M2 D 1,8,15 Q28 IV. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5587018-0
Topotecan side effect was reported by a Physician from UNITED STATES on Jan 07, 2008. Female patient was diagnosed with pain  and was treated with Topotecan. After drug was administered, patient experienced the following side effects: alanine aminotransferase abnormal, aspartate aminotransferase abnormal, asthenia, blood creatinine abnormal, decreased appetite, dysphonia, failure to thrive, fatigue, haemoglobin abnormal. Topotecan dosage: 3.3MG CYCLIC. During the same period patient was treated with BEVACIZUMAB, CISPLATIN, VERAPAMIL, HYDROCHLOROTHIAZIDE, METOPROLOL, PERCOCET, MORPHINE, ZOFRAN. Patient was hospitalized. Patient recovered.

Topotecan Side Effects Report #5027785-8
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 14, 2006. Female patient, weighting 104.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: asthenia, bedridden, decreased appetite, dehydration, fatigue, haemoglobin decreased, hypomagnesaemia, hyponatraemia, nausea . Topotecan dosage: 12 MG. Patient was hospitalized. Patient recovered.


Topotecan Side Effects Report #5038669-3
Topotecan side effect was reported by a Consumer or non-health professional from UNITED STATES on June 27, 2006. Female patient, weighting 104.2 lb, was treated with Topotecan. After drug was administered, patient experienced the following side effects: abasia, anxiety , asthenia, bedridden, blood culture positive, decreased appetite, dehydration, fatigue, haemoglobin decreased. Topotecan dosage: 12 MG. Patient was hospitalized. Patient recovered.