Timoptic and metastases to lymph nodes Patient Reports February 12, 2012

Timoptic Side Effects Report #5078287-4
Timoptic side effect was reported by a Physician from JAPAN on May 18, 2006. Female patient, 56 years of age, weighting 108.0 lb, was diagnosed with intraocular pressure increased, conjunctival hyperaemia, conjunctivitis and was treated with Timoptic. After drug was administered, patient experienced the following side effects: breast cancer metastatic, cataract nuclear, cataract subcapsular, keratopathy, metastases to central nervous system, metastases to lymph nodes, vocal cord paralysis. Timoptic dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, FLUMETHOLON. Patient was hospitalized. Patient died on 10/12/2005.

Timoptic Side Effects Report #5011982-1
Timoptic side effect was reported by a Physician from JAPAN on May 18, 2006. Female patient, 56 years of age, was treated with Timoptic. After drug was administered, patient experienced the following side effects: cataract nuclear, cataract subcapsular, corneal disorder, keratopathy, metastases to lymph nodes, vocal cord paralysis. Timoptic dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, FLUOROMETHOLONE, BRINZOLAMIDE, HYALURONATE. Patient recovered.

Timoptic Side Effects Report #5017270-1
Timoptic side effect was reported by a Physician from JAPAN on May 18, 2006. Female patient, 56 years of age, was treated with Timoptic. After drug was administered, patient experienced the following side effects: cataract nuclear, cataract subcapsular, corneal disorder, dysphonia, keratopathy, metastases to lymph nodes, somnolence, treatment noncompliance, vocal cord paralysis. Timoptic dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, FLUOROMETHOLONE, BRINZOLAMIDE, HYALURONATE. Patient recovered.

Timoptic Side Effects Report #5028532-6
Timoptic side effect was reported by a Physician from JAPAN on May 18, 2006. Female patient, 56 years of age, was treated with Timoptic. After drug was administered, patient experienced the following side effects: asthenia, cataract nuclear, cataract subcapsular, hypersomnia, keratitis, keratopathy, metastases to central nervous system, metastases to lymph nodes, oral intake reduced. Timoptic dosage: unknown. During the same period patient was treated with LEVOFLOXACIN, FLUOROMETHOLONE, BRINZOLAMIDE, HYALURONATE. Patient recovered.