Thymoglobulin and multi-organ failure Patient Reports February 12, 2012

Thymoglobulin Side Effects Report #5794502-3
Thymoglobulin side effect was reported by a Physician from NETHERLANDS on June 06, 2008. Male patient, 61 years of age, weighting 183.0 lb, was diagnosed with stem cell transplant, t-cell depletion and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , epstein-barr virus infection, multi-organ failure, pneumonia cytomegaloviral. Thymoglobulin dosage: 175 MG, QD, INTRAVENOUS. During the same period patient was treated with BUSULFAN, FLUDARABINE PHOSPHATE, CAMPATH. Patient was hospitalized. Patient died on 03/08/2008.

Thymoglobulin Side Effects Report #4629569-9
Thymoglobulin side effect was reported by a Physician from on Mar 17, 2005. Male patient, 56 years of age, weighting 213.8 lb, was diagnosed with stem cell transplant and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Thymoglobulin dosage: 175 MG QD IV. During the same period patient was treated with TREOSULFAN, FLUDARABIN. Patient died on 01/07/2005.

Thymoglobulin Side Effects Report #4656057-6
Thymoglobulin side effect was reported by a Physician from on Apr 21, 2005. Male patient, 56 years of age, weighting 213.8 lb, was diagnosed with stem cell transplant and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Thymoglobulin dosage: 175 MG QD IV. During the same period patient was treated with TREOSULFAN, FLUDARABIN. Patient died on 01/07/2005.

Thymoglobulin Side Effects Report #4629569-9
Thymoglobulin side effect was reported by a Physician from GERMANY on Mar 17, 2005. Male patient, 56 years of age, weighting 213.8 lb, was diagnosed with stem cell transplant and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: multi-organ failure, sepsis . Thymoglobulin dosage: 175 MG QD IV. During the same period patient was treated with TREOSULFAN, FLUDARABIN. Patient died on 01/07/2005.


Thymoglobulin Side Effects Report #5794500-X
Thymoglobulin side effect was reported by a Physician from NETHERLANDS on June 06, 2008. Female patient, 46 years of age, weighting 114.6 lb, was diagnosed with stem cell transplant, t-cell depletion, cytomegalovirus infection  and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , epstein-barr virus infection, liver disorder, multi-organ failure, pancytopenia, post transplant lymphoproliferative disorder, spleen disorder. Thymoglobulin dosage: 300 MG, QD, INTRAVENOUS. During the same period patient was treated with FLUDARABINE, BUSULPHAN, CAMPATH, GANCICLOVIR. Patient was hospitalized. Patient died on 05/25/2007.

Thymoglobulin Side Effects Report #5794498-4
Thymoglobulin side effect was reported by a Physician from NETHERLANDS on June 06, 2008. Female patient, 32 years of age, weighting 127.9 lb, was diagnosed with stem cell transplant, t-cell depletion and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: bone marrow transplant rejection, bronchopulmonary aspergillosis, epstein-barr virus infection, multi-organ failure, post transplant lymphoproliferative disorder. Thymoglobulin dosage: 175 MG, QD, INTRAVENOUS. During the same period patient was treated with BUSULPHAN, FLUDARABINE, CAMPATH. Patient was hospitalized. Patient died on 09/29/2007.

Thymoglobulin Side Effects Report #5531289-3
Thymoglobulin side effect was reported by a Physician from GERMANY on Oct 26, 2007. Male patient, 57 years of age, was diagnosed with renal transplant and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , kidney transplant rejection, leukopenia, multi-organ failure, pneumocystis jiroveci pneumonia, pneumonia primary atypical, septic shock, urinary tract infection . Thymoglobulin dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient died on 09/18/2007.

Thymoglobulin Side Effects Report #4690820-0
Thymoglobulin side effect was reported by a Health Professional from on May 27, 2005. Male patient, 60 years of age, weighting 187.8 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: bone marrow depression, hepatic failure, multi-organ failure, pneumonia fungal, transplant rejection. Thymoglobulin dosage: 0.5 MG/KG QD IV. During the same period patient was treated with FLUDARABINE PHOSPHATE, BUSULFAN. Patient died on 05/25/2005.

Thymoglobulin Side Effects Report #4690821-2
Thymoglobulin side effect was reported by a Health Professional from on May 27, 2005. Male patient, 60 years of age, weighting 187.8 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: hyperbilirubinaemia, multi-organ failure, pleural effusion, pneumonia fungal, zygomycosis. Thymoglobulin dosage: 0.5 MG/KG QD IV. Patient was hospitalized. Patient died on 05/25/2005.


Thymoglobulin Side Effects Report #5548918-0
Thymoglobulin side effect was reported by a Physician from GERMANY on Nov 19, 2007. Male patient, 57 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , haemodialysis, leukopenia, multi-organ failure, no therapeutic response, pneumocystis jiroveci pneumonia, pneumonia primary atypical, septic shock, transplant rejection. Thymoglobulin dosage: 25 MG QD IV. During the same period patient was treated with CYCLOSPORINE, MYCOPHENOLATE MOFETIL, URBASON, CYTOTECT. Patient was hospitalized. Patient died on 09/18/2007.

Thymoglobulin Side Effects Report #6092079-9
Thymoglobulin side effect was reported by a Physician from JAPAN on Jan 31, 2009. Male patient, 54 years of age, weighting 132.3 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: cardiac arrest , depressed level of consciousness, disease progression, infection , lymphoma , multi-organ failure, pyrexia, renal failure, transplant failure. Thymoglobulin dosage: 2.5 MG/KG, QD, INTRAVENOUS. During the same period patient was treated with FLUDARABINE PHOSPHATE, MELPHALAN. Patient died on 01/03/2009.

Thymoglobulin Side Effects Report #4976845-6
Thymoglobulin side effect was reported by a Physician from UNITED STATES on Mar 22, 2006. Male patient, 47 years of age, weighting 230.2 lb, was diagnosed with non-hodgkin's lymphoma and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: collapse of lung, depressed level of consciousness, diarrhoea, disease progression, haemolysis, infection , multi-organ failure, renal failure. Thymoglobulin dosage: 1.5 MG/KG QOD IV. During the same period patient was treated with ACYCLOVIR, FLAGYL, VANCOMYCIN, CASPOFUNGIN, GRANULOCYTE, LEVAQUIN, AZTREONAM. Patient died on 01/21/2006.

Thymoglobulin Side Effects Report #5751711-7
Thymoglobulin side effect was reported by a Physician from UNITED STATES on May 12, 2008. Male patient, 54 years of age, weighting 163.8 lb, was diagnosed with myeloid leukaemia and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, hyperbilirubinaemia, mucosal inflammation, multi-organ failure, renal failure acute, respiratory distress, staphylococcal infection . Thymoglobulin dosage: 1, 2.5 MG/M2 QD. During the same period patient was treated with CLOFARABINE, CYTARABINE, CEFEPIME, DEXAMETHASONE, NEXIUM, FAMOTIDINE, SINGULAIR. Patient died on 04/28/2008.

Thymoglobulin Side Effects Report #5781210-8
Thymoglobulin side effect was reported by a Consumer or non-health professional from UNITED STATES on May 28, 2008. Male patient, 54 years of age, weighting 163.8 lb, was diagnosed with myeloid leukaemia and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, blood culture positive, blood sodium increased, hyperbilirubinaemia, mucosal inflammation, multi-organ failure, renal failure acute. Thymoglobulin dosage: 1 MG/M2 QD,; 2.5 MG/M2, QD. During the same period patient was treated with CLOFARABINE, CYTARABINE, CEFEPIME, DEXAMETHASONE, NEXIUM, FAMOTIDINE, SINGULAIR. Patient died on 04/28/2008.


Thymoglobulin Side Effects Report #5014697-9
Thymoglobulin side effect was reported by a Physician from GERMANY on May 08, 2006. Male patient, 65 years of age, weighting 194.0 lb, was diagnosed with liver transplant  and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: bile duct necrosis, complications of transplanted liver, lung infection pseudomonal, multi-organ failure, prothrombin time prolonged, sepsis , systemic inflammatory response syndrome. Thymoglobulin dosage: 1.5 MG/KG ONCE IV. During the same period patient was treated with FLUCONAZOLE, CASPOFUNGIN, LINEZOLID, FUROSEMIDE. Patient was hospitalized. Patient died on 01/23/2006.

Thymoglobulin Side Effects Report #5424014-8
Thymoglobulin side effect was reported by a Physician from FRANCE on Oct 05, 2006. Male patient, 62 years of age, weighting 235.9 lb, was diagnosed with liver transplant  and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: hepatic function abnormal, intra-abdominal haemorrhage, multi-organ failure, post procedural haemorrhage, renal failure acute. Thymoglobulin dosage: 1.5 MG/KG QOD IV. During the same period patient was treated with MOPRAL, TAZOCILLINE, NORADRENALINE, CYCLOSPORINE, TACAROLIMUS. Patient was hospitalized. Patient died on 12/21/2005.

Thymoglobulin Side Effects Report #5489005-X
Thymoglobulin side effect was reported by a Health Professional from FRANCE on Sept 21, 2007. Male patient, 49 years of age, weighting 187.4 lb, was diagnosed with liver transplant  and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: biliary anastomosis complication, multi-organ failure, pancreatitis acute, pancreatitis necrotising. Thymoglobulin dosage: 1.5 MG/KG QD IV. During the same period patient was treated with ZOPHREN, TRIATEC, PROGRAF, CELLCEPT. Patient died on 05/09/2007.

Thymoglobulin Side Effects Report #5507288-4
Thymoglobulin side effect was reported by a Health Professional from FRANCE on Oct 15, 2007. Male patient, 49 years of age, weighting 187.4 lb, was diagnosed with liver transplant  and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: biliary anastomosis complication, biliary dilatation, cholestasis, multi-organ failure, pancreatitis necrotising. Thymoglobulin dosage: 1.5 MG/KG QD IV. During the same period patient was treated with ZOPHREN, TRIATEC, PROGRAF, CELLCEPT. Patient died on 05/09/2007.

Thymoglobulin Side Effects Report #5136811-7
Thymoglobulin side effect was reported by a Physician from FRANCE on Oct 05, 2006. Female patient, 48 years of age, weighting 119.0 lb, was diagnosed with liver transplant  and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: atelectasis, disease recurrence, hepatitis c , hepatopulmonary syndrome, hypoxia, liver transplant rejection, multi-organ failure, respiratory failure. Thymoglobulin dosage: 1.5 MG/KG QD IV. During the same period patient was treated with OMEPRAZOLE, HYPNOVEL, PROGRAF, SUFENTA, METHYLPREDNISOLONE. Patient was hospitalized. Patient died on 08/17/2005.


Thymoglobulin Side Effects Report #5140624-X
Thymoglobulin side effect was reported by a Physician from FRANCE on Oct 05, 2006. Female patient, 48 years of age, weighting 119.0 lb, was diagnosed with liver transplant  and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: atelectasis, disease recurrence, hepatitis c , hepatopulmonary syndrome, liver transplant rejection, multi-organ failure, respiratory failure. Thymoglobulin dosage: 1.5 MG/KG QD IV. During the same period patient was treated with OMEPRAZOLE, HYPNOVEL, PROGRAF, SUFENTA, METHYLPREDNISOLONE. Patient was hospitalized. Patient died on 08/17/2005.

Thymoglobulin Side Effects Report #4838104-1
Thymoglobulin side effect was reported by a Physician from GERMANY on Nov 09, 2005. Male patient, 49 years of age, weighting 160.9 lb, was diagnosed with immunosuppression and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: adhesion , hepatic cirrhosis, hepatitis c virus, infection , multi-organ failure, peritonitis, portal vein thrombosis. Thymoglobulin dosage: 100 MG QD. Patient died on 09/22/2005.

Thymoglobulin Side Effects Report #4746348-2
Thymoglobulin side effect was reported by a Physician from ITALY on July 27, 2005. Male patient, 16 years of age, was diagnosed with graft versus host disease and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , multi-organ failure. Thymoglobulin dosage: 1.25 MG/KG QOD IV. During the same period patient was treated with PREDNISONE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, EXTRACORPOREAL PHOTOPHERESIS. Patient was hospitalized. Patient died.

Thymoglobulin Side Effects Report #4895249-8
Thymoglobulin side effect was reported by a Physician from ITALY on Jan 09, 2006. Male patient, 16 years of age, was diagnosed with graft versus host disease and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , disease recurrence, multi-organ failure. Thymoglobulin dosage: 1.25 MG/KG QOD IV. During the same period patient was treated with PREDNISONE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, EXTRACORPOREAL PHOTOPHERESIS. Patient was hospitalized. Patient died.

Thymoglobulin Side Effects Report #5491379-0
Thymoglobulin side effect was reported by a Physician from AUSTRALIA on Sept 28, 2007. Female patient was diagnosed with bone marrow transplant , immunosuppression and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: multi-organ failure, venoocclusive disease. Thymoglobulin dosage: 0.5 MG/KG QD. Patient died.


Thymoglobulin Side Effects Report #4873290-9
Thymoglobulin side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 13, 2005. Female patient, 35 years of age, was diagnosed with bone marrow conditioning regimen and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: epstein-barr virus infection, graft versus host disease in skin, lymphoproliferative disorder, multi-organ failure. Thymoglobulin dosage: 10 MG/KG QD; IV. During the same period patient was treated with CYCLOPHOSPHAMIDE. Patient died.

Thymoglobulin Side Effects Report #6081323-X
Thymoglobulin side effect was reported by a Physician from JAPAN on Jan 28, 2009. Male patient, 24 years of age, was diagnosed with aplastic anaemia and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood creatine phosphokinase increased, blood lactate dehydrogenase increased, haemorrhagic diathesis, herpes virus infection, multi-organ failure. Thymoglobulin dosage: 3.2 MG/KG, QD, INTRAVENOUS. During the same period patient was treated with CYCLOSPORINE, ACYCLOVIR, FENTANYL CITRATE, PLASMA. Patient died on 01/01/2009.

Thymoglobulin Side Effects Report #5751718-X
Thymoglobulin side effect was reported by a Physician from UNITED STATES on May 02, 2008. Male patient, 54 years of age, weighting 163.8 lb, was diagnosed with acute myeloid leukaemia and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: dyspnoea, hyperbilirubinaemia, mucosal inflammation, multi-organ failure, renal failure acute, toxic epidermal necrolysis. Thymoglobulin dosage: 1 MG/M2, QD,; 2.5 MG/M2, QD,. During the same period patient was treated with CLOFARABINE, CYTARABINE, CEFEPIME, DEXAMETHASONE, NEXIUM, FAMOTIDINE, SINGULAIR. Patient died on 04/28/2008.

Thymoglobulin Side Effects Report #5873076-2
Thymoglobulin side effect was reported by a Physician from UNITED STATES on Aug 14, 2008. Male patient, 54 years of age, weighting 163.8 lb, was diagnosed with acute myeloid leukaemia and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: blood culture positive, bone marrow transplant , fungal infection , hyperbilirubinaemia, mucosal inflammation, multi-organ failure, renal failure acute, respiratory distress, staphylococcal infection . Thymoglobulin dosage: 1 MG/M2, QD, UNK, 2.5 MG/M2, QD UNK. During the same period patient was treated with CLOFARABINE, CYTARABINE, CEFEPIME, DEXAMETHASONE, NEXIUM, FAMOTIDINE, SINGULAIR. Patient died on 04/28/2008.

Thymoglobulin Side Effects Report #5922396-1
Thymoglobulin side effect was reported by a Physician from UNITED STATES on Sept 05, 2008. Male patient, 54 years of age, weighting 163.8 lb, was diagnosed with acute myeloid leukaemia and was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: blood chloride increased, blood culture positive, blood sodium increased, communication disorder, mucosal inflammation, multi-organ failure, oedema, renal failure acute, respiratory distress. Thymoglobulin dosage: 1 MG/KG, QD, INTRAVENOUS; 2.5 MG/KG, QD, INTRAVENOUS. During the same period patient was treated with CLOFARABINE, CYTARABINE, CEFEPIME, DEXAMETHASONE, NEXIUM, FAMOTIDINE, SINGULAIR. Patient died on 04/28/2008.


Thymoglobulin Side Effects Report #4688885-5
Thymoglobulin side effect was reported by a Physician from on May 18, 2005. Male patient, 70 years of age, was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: mucormycosis, multi-organ failure. Thymoglobulin dosage: unknown. Patient died on 05/04/2005.

Thymoglobulin Side Effects Report #5873081-6
Thymoglobulin side effect was reported by a Physician from UNITED STATES on Aug 11, 2008. Female patient was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: abo incompatibility, haemolysis, multi-organ failure. Thymoglobulin dosage: unknown. Patient recovered.

Thymoglobulin Side Effects Report #5936749-9
Thymoglobulin side effect was reported by a Physician from UNITED STATES on Oct 09, 2008. Female patient was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: haemolysis, multi-organ failure. Thymoglobulin dosage: unknown. Patient recovered.

Thymoglobulin Side Effects Report #5944287-2
Thymoglobulin side effect was reported by a Physician from UNITED STATES on Oct 22, 2008. Female patient was treated with Thymoglobulin. After drug was administered, patient experienced the following side effects: haemolysis, multi-organ failure. Thymoglobulin dosage: unknown. Patient recovered.