Thalidomide and osteonecrosis Patient Reports February 10, 2012

Thalidomide Side Effects Report #4657587-3
Thalidomide side effect was reported by a Consumer or non-health professional from on Apr 20, 2005. Female patient, 84 years of age, was diagnosed with multiple myeloma , diabetes mellitus, hypertension and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: infection , osteomyelitis, osteonecrosis . Thalidomide dosage: 50 MG, QD. During the same period patient was treated with RADIATION, AREDIA, INSULIN, PREDNISONE, INDAPAMIDE, ATENOLOL, PROTONIX. Patient recovered.

Thalidomide Side Effects Report #5716164-3
Thalidomide side effect was reported by a Health Professional from UNITED STATES on Apr 17, 2008. Male patient, 81 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: osteonecrosis . Thalidomide dosage: unknown. During the same period patient was treated with DEXAMETHASONE, PAMIDRONATE DI. Patient recovered.

Thalidomide Side Effects Report #5717199-7
Thalidomide side effect was reported by a Health Professional from UNITED STATES on Apr 17, 2008. Male patient, 81 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: osteonecrosis . Thalidomide dosage: unknown. During the same period patient was treated with DEXAMETHASONE, PAMIDRONATE DI. Patient recovered.

Thalidomide Side Effects Report #4667128-2
Thalidomide side effect was reported by a Consumer or non-health professional from on Mar 22, 2004. Male patient, 79 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: abscess , abscess drainage, jaw disorder, osteonecrosis . Thalidomide dosage: 200 MG, QD. During the same period patient was treated with ZOMETA. Patient recovered.


Thalidomide Side Effects Report #4939284-X
Thalidomide side effect was reported by a Consumer or non-health professional from UNITED KINGDOM on Feb 27, 2006. Female patient, 74 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: osteonecrosis . Thalidomide dosage: 100MG/DAY. During the same period patient was treated with TRAMADOL, ZOMETA. Patient recovered.

Thalidomide Side Effects Report #5238218-0
Thalidomide side effect was reported by a Physician from AUSTRIA on Feb 02, 2007. Male patient, 71 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: balance disorder, concomitant disease progression, osteolysis, osteonecrosis , polyneuropathy. Thalidomide dosage: 100 MG, QD. During the same period patient was treated with INTRON A, ZOLEDRONATE. Patient was hospitalized. Patient recovered.

Thalidomide Side Effects Report #5256024-8
Thalidomide side effect was reported by a Physician from AUSTRIA on Feb 23, 2007. Male patient, 71 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: anaemia, balance disorder, concomitant disease progression, osteolysis, osteonecrosis , polyneuropathy, therapeutic procedure. Thalidomide dosage: 100 MG, QD. During the same period patient was treated with INTRON A, ZOLEDRONATE, PLAVIX, DIABETEX, PANTOPRAZOLE, AMARYL, ISOPTIN, ATACAND. Patient was hospitalized. Patient recovered.

Thalidomide Side Effects Report #5277070-4
Thalidomide side effect was reported by a Physician from AUSTRIA on Mar 16, 2007. Male patient, 71 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: anaemia, balance disorder, bone disorder, concomitant disease progression, oral intake reduced, oral surgery, osteolysis, osteonecrosis , pain . Thalidomide dosage: 100 MG, QD. During the same period patient was treated with INTRON A, ZOLEDRONATE, PLAVIX, DIABETEX, PANTOPRAZOLE, AMARYL, ISOPTIN, ATACAND. Patient was hospitalized. Patient recovered.

Thalidomide Side Effects Report #5198890-0
Thalidomide side effect was reported by a Consumer or non-health professional from SWITZERLAND on Dec 22, 2006. Female patient, 63 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: osteonecrosis , wound debridement. Thalidomide dosage: unknown. During the same period patient was treated with MELPHALAN, ZOMETA, DEXAMETHASONE, DOXORUBICIN, VINCRISTINE, HEMATOPOETIC PROGENITOR CELLS. Patient recovered.


Thalidomide Side Effects Report #6122102-4
Thalidomide side effect was reported by a Physician from AUSTRALIA on Mar 09, 2009. Male patient, 62 years of age, was diagnosed with multiple myeloma , herpes zoster and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: ankle fracture, femur fracture, fistula , neuropathy peripheral, osteonecrosis , rib fracture, sepsis , septic shock, tibia fracture. Thalidomide dosage: unknown. During the same period patient was treated with PAMIDRONATE DI, ZOLEDRONIC ACID, PREDNISOLONE, CYCLOPHOSPHAMIDE, MELPHALAN, VALACYCLOVIR. Patient was hospitalized and became disabled. Patient died on 01/01/2007.

Thalidomide Side Effects Report #5032882-7
Thalidomide side effect was reported by a Consumer or non-health professional from UNITED STATES on May 17, 2006. Male patient, 61 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: anaemia of malignant disease, deep vein thrombosis , dental treatment, erythema, local swelling, oral pain, osteonecrosis , tooth abscess, tooth extraction. Thalidomide dosage: 100 MG, DAILY. During the same period patient was treated with VELCADE, MELPHALAN, REVLIMID, DEXAMETHASONE, PREDNISONE, ZOMETA. Patient recovered.

Thalidomide Side Effects Report #5040459-2
Thalidomide side effect was reported by a Consumer or non-health professional from UNITED STATES on May 17, 2006. Male patient, 61 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: anaemia of malignant disease, bone disorder, deep vein thrombosis , dental prosthesis placement, enanthema, local swelling, oral pain, osteonecrosis , tooth abscess. Thalidomide dosage: 100 MG, DAILY. During the same period patient was treated with VELCADE, MELPHALAN, REVLIMID, DEXAMETHASONE, PREDNISONE, ZOMETA. Patient recovered.

Thalidomide Side Effects Report #5113901-6
Thalidomide side effect was reported by a Physician from UNITED STATES on Sept 18, 2006. Female patient, 56 years of age, weighting 112.0 lb, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: deep vein thrombosis , fall , head injury, osteonecrosis , spinal fracture, spondylolisthesis. Thalidomide dosage: unknown. During the same period patient was treated with DEXAMETHASONE, DILAUDID, MS CONTIN, XANAX, SYNTHROID, PLAQEUNIL. Patient was hospitalized. Patient recovered.

Thalidomide Side Effects Report #5153919-0
Thalidomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 05, 2006. Female patient was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: abscess drainage, osteonecrosis . Thalidomide dosage: 200 MG, QD. During the same period patient was treated with DEXAMETHASONE, ZOMETA. Patient recovered.


Thalidomide Side Effects Report #5245381-4
Thalidomide side effect was reported by a Health Professional from CHILE on Feb 13, 2007. Male patient, 84 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: anaemia, bone disorder, excessive granulation tissue, gait disturbance, muscle fatigue, osteonecrosis , tooth disorder , tooth extraction. Thalidomide dosage: 100 MG/D. During the same period patient was treated with DEXAMETHASONE, TRANSFUSIONS, EPOGEN, ZOLEDRONIC ACID. Patient recovered.

Thalidomide Side Effects Report #4971494-8
Thalidomide side effect was reported by a Physician from UNITED STATES on Mar 10, 2006. Female patient, 78 years of age, was diagnosed with metastases to bone and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: oral soft tissue disorder, osteonecrosis . Thalidomide dosage: unknown. During the same period patient was treated with DECADRON, ZOMETA. Patient recovered.

Thalidomide Side Effects Report #4821564-X
Thalidomide side effect was reported by a Physician from FRANCE on July 22, 2005. Female patient, 75 years of age, weighting 110.2 lb, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: osteonecrosis , surgery , tooth extraction, tooth infection. Thalidomide dosage: unknown. During the same period patient was treated with ZOMETA. Patient recovered.

Thalidomide Side Effects Report #5703682-7
Thalidomide side effect was reported by a Consumer or non-health professional from FRANCE on Apr 04, 2008. Male patient, 73 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: bone disorder, debridement, impaired healing, osteonecrosis . Thalidomide dosage: unknown. During the same period patient was treated with CORTICOSTEROIDS, ZOMETA. Patient was hospitalized. Patient recovered.

Thalidomide Side Effects Report #4881603-7
Thalidomide side effect was reported by a Physician from AUSTRALIA on Apr 20, 2005. Male patient, 69 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: dental operation, osteonecrosis , tooth loss, wound debridement. Thalidomide dosage: unknown. During the same period patient was treated with DEXAMETHASONE, AREDIA, ZOMETA. Patient recovered.


Thalidomide Side Effects Report #4667088-4
Thalidomide side effect was reported by a Physician from on Apr 12, 2005. Male patient, 67 years of age, was treated with Thalidomide. After drug was administered, patient experienced the following side effects: actinomycosis, osteitis, osteonecrosis , pain in jaw. Thalidomide dosage: unknown. During the same period patient was treated with DEXAMETHASONE, ZOMETA. Patient recovered.

Thalidomide Side Effects Report #4726110-7
Thalidomide side effect was reported by a Physician from BELGIUM on Apr 12, 2005. Male patient, 67 years of age, was treated with Thalidomide. After drug was administered, patient experienced the following side effects: actinomycosis, hypertension, osteitis, osteonecrosis , pain in jaw, proteinuria. Thalidomide dosage: unknown. During the same period patient was treated with DEXAMETHASONE, ZOMETA, AREDIA, BONEFOS. Patient recovered.

Thalidomide Side Effects Report #4667270-6
Thalidomide side effect was reported by a Physician from on Sept 07, 2004. Male patient, 66 years of age, was diagnosed with prostate cancer  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: endodontic procedure, impaired healing, jaw disorder, osteonecrosis , tooth extraction. Thalidomide dosage: unknown. During the same period patient was treated with TESTOSTERONE, CALCITRIOL, ESTINYL, PROSCAR, LEUKINE, BIAXIN, ANDROGENS, COUMADIN. Patient recovered.

Thalidomide Side Effects Report #5578596-6
Thalidomide side effect was reported by a Consumer or non-health professional from ITALY on Dec 24, 2007. Male patient, 64 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: osteonecrosis . Thalidomide dosage: 50 MG, UNK. During the same period patient was treated with GLYBURIDE AND METFORMIN, ASPIRIN, ZOMETA. Patient recovered.

Thalidomide Side Effects Report #4957667-9
Thalidomide side effect was reported by a Physician from AUSTRIA on Oct 04, 2005. Female patient, 63 years of age, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: bone trimming, osteomyelitis, osteonecrosis . Thalidomide dosage: 400 MG/D. During the same period patient was treated with ZOMETA. Patient was hospitalized. Patient recovered.


Thalidomide Side Effects Report #5672374-5
Thalidomide side effect was reported by a Physician from UNITED STATES on Mar 12, 2008. Female patient, 60 years of age, was diagnosed with hypercalcaemia of malignancy and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: gingival disorder, osteonecrosis , tooth extraction. Thalidomide dosage: unknown. During the same period patient was treated with DEXAMETHASONE, ZOMETA. Patient recovered.

Thalidomide Side Effects Report #4677703-7
Thalidomide side effect was reported by a Physician from on Feb 23, 2005. Female patient, 55 years of age, was diagnosed with light chain analysis increased and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: aseptic necrosis bone, bone infection, bone lesion, jaw disorder, osteonecrosis , pain in jaw, wound debridement. Thalidomide dosage: unknown. During the same period patient was treated with MAGNESIUM, TENORMIN, ZOMETA, AREDIA. Patient recovered.

Thalidomide Side Effects Report #5031425-1
Thalidomide side effect was reported by a Physician from FRANCE on June 09, 2006. Female patient, weighting 158.7 lb, was diagnosed with multiple myeloma  and was treated with Thalidomide. After drug was administered, patient experienced the following side effects: open wound, osteonecrosis , tooth extraction. Thalidomide dosage: unknown. During the same period patient was treated with ZOMETA. Patient recovered.