Temozolomide and malignant neoplasm progression 
Temozolomide and malignant neoplasm progression Patient Reports February 11, 2012
Temozolomide Side Effects Report #5713624-6
Temozolomide side effect was reported by a Physician from SWITZERLAND on Apr 11, 2008. Female patient, 63 years of age, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: infection
, liver disorder, malignant neoplasm progression. Temozolomide dosage: 240 MG; ; PO. During the same period patient was treated with BEVACIZUMAB. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5469777-0
Temozolomide side effect was reported by a Physician from UNITED STATES on Sept 26, 2007. Female patient, 59 years of age, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: antinuclear antibody positive, aplastic anaemia, bone marrow failure, ecchymosis, malignant neoplasm progression, metastases to liver, metastases to soft tissue, metastases to spleen, skin haemorrhage. Temozolomide dosage: 140 MG DAILY PO. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5522153-4
Temozolomide side effect was reported by a Physician from GERMANY on Nov 07, 2007. Male patient, 58 years of age, weighting 180.8 lb, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: malignant neoplasm progression, metastases to liver, metastases to lung, pneumonia
, pulmonary oedema, surgical procedure repeated. Temozolomide dosage: 300 MG;QOW;PO. During the same period patient was treated with MORPHINE. Patient was hospitalized. Patient died on 07/04/2006.Temozolomide Side Effects Report #5901964-7
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Sept 24, 2008. Male patient, 36 years of age, weighting 253.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorexia, asthenia, cough, failure to thrive, flank pain, malignant neoplasm progression, metastatic malignant melanoma, nausea
, weight decreased. Temozolomide dosage: 100 MG;QD;PO, 60 MG;QD;PO,15 MG;QD;PO. During the same period patient was treated with DECITABINE, OXYCONTIN, DECADRON. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5672501-X
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Mar 18, 2008. Female patient, weighting 202.8 lb, was diagnosed with metastasis, sarcoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: atrial fibrillation
, atrial flutter, lung cancer metastatic, malignant neoplasm progression, pleural effusion. Temozolomide dosage: 28 MG X 5 MG 24 HR INFUSION IV. During the same period patient was treated with METHOXYAMINE, PAXIL, VYTORIN, TRICOR, COLACE, MAGOXIDE, OXYCODONE. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5306552-1
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Apr 10, 2007. Male patient, 62 years of age, was diagnosed with metastases to central nervous system and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: haemorrhage intracranial, malignant neoplasm progression, neutropenia, sepsis
, thrombocytopenia. Temozolomide dosage: 150 MG/M2; QD; PO. During the same period patient was treated with LOMUSTINE, LANSOPRAZOLE, LIQUID PARAFFIN, MAGNESIUM HYDROXIDE. Patient died on 12/09/2001.Temozolomide Side Effects Report #5972603-4
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 19, 2008. Male patient, 68 years of age, was diagnosed with malignant glioma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, dehydration, fall
, gait disturbance, malignant neoplasm progression. Temozolomide dosage: unknown. Patient was hospitalized. Patient died on 10/05/2008.Temozolomide Side Effects Report #5152979-0
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 10, 2006. Male patient, 19 years of age, weighting 132.3 lb, was diagnosed with gliomatosis cerebri, meningeal neoplasm and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: blood pressure increased, confusional state, gliomatosis cerebri, grand mal convulsion, headache
, intention tremor, malignant neoplasm progression, memory impairment, meningeal neoplasm. Temozolomide dosage: 250 MG DAILY FOR 5 DAYS BUCCAL. During the same period patient was treated with TEMOZOLOMIDE SCHERING. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5012359-5
Temozolomide side effect was reported by a Health Professional from UNITED STATES on May 25, 2006. Female patient, 57 years of age, weighting 116.8 lb, was diagnosed with glioma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: fall
, hemiparesis, hypoaesthesia, malignant neoplasm progression. Temozolomide dosage: 75 MG/M2 QD X 49 DAY CYCLE PO. During the same period patient was treated with DILANTIN, KEPPRA, KLONOPIN, PRILOSEC, ZOFRAN, BACTRIM DS, TRILEPTAL, DECADRON. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5223418-6
Temozolomide side effect was reported by a Physician from JAPAN on Jan 18, 2007. Female patient, 66 years of age, weighting 103.6 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abdominal distension, gastric cancer, malignant neoplasm progression. Temozolomide dosage: 75 MG/M2;QD;PO; SEE IMAGE. During the same period patient was treated with NASEA OD, GLIMICRON. Patient recovered.
Temozolomide Side Effects Report #5379845-X
Temozolomide side effect was reported by a Health Professional from JAPAN on June 25, 2007. Male patient, 65 years of age, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: convulsion, glioblastoma multiforme, malignant neoplasm progression, necrosis, radiation injury. Temozolomide dosage: unknown. Patient died on 06/08/2007.
Temozolomide Side Effects Report #5501311-9
Temozolomide side effect was reported by a Physician from UNITED STATES on Oct 19, 2007. Female patient, 59 years of age, weighting 194.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, candidiasis, cushing's syndrome, glioblastoma multiforme, lymphopenia, malignant neoplasm progression. Temozolomide dosage: 75 MG/M2;QD;PO. During the same period patient was treated with BACTRIM DS, DECADRON, KEPPRA. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5514826-4
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 05, 2007. Female patient, 59 years of age, weighting 194.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: cushing's syndrome, glioblastoma multiforme, lymphopenia, malignant neoplasm progression, opportunistic infection, oral candidiasis. Temozolomide dosage: 75 MG/M2;QD;PO ; 1450 MG; PO. During the same period patient was treated with BACTRIM DS, DECADRON, KEPPRA. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5527445-0
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 19, 2007. Female patient, 59 years of age, weighting 194.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: cushing's syndrome, glioblastoma multiforme, lymphopenia, malignant neoplasm progression, oral candidiasis. Temozolomide dosage: 75 MG/M2; QD; PO; 1450 MG; PO. During the same period patient was treated with BACTRIM DS, DECADRON, KEPPRA. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5532369-9
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 20, 2007. Female patient, 59 years of age, weighting 194.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, cushing's syndrome, glioblastoma multiforme, lymphopenia, malignant neoplasm progression, oral candidiasis. Temozolomide dosage: 75 MG/M2;QD;PO ; 1450 MG;PO. During the same period patient was treated with BACTRIM DS, DECADRON, KEPPRA. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5403510-3
Temozolomide side effect was reported by a Physician from JAPAN on July 26, 2007. Female patient, 57 years of age, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: altered state of consciousness, cardiac arrest
, hydrocephalus , lymphocyte count decreased, malignant neoplasm progression, pupillary reflex impaired, respiratory arrest. Temozolomide dosage: 110 MG; QD; PO, 200 MG; QD; PO. Patient died on 07/14/2007.Temozolomide Side Effects Report #5530346-5
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Nov 27, 2007. Male patient, 55 years of age, weighting 185.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: amnesia, glioblastoma multiforme, hemiparesis, malignant neoplasm progression. Temozolomide dosage: 50MG/M2 PO DAILY. During the same period patient was treated with BEVACIZUMAB, KEPPRA, DILANTIN, DECADRON, HYDROCHLOROTHIAZIDE, ZANTAC, METFORMIN. Patient died on 10/16/2007.
Temozolomide Side Effects Report #5372538-4
Temozolomide side effect was reported by a Health Professional from UNITED STATES on June 18, 2007. Male patient, 51 years of age, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: malignant neoplasm progression, no therapeutic response. Temozolomide dosage: 120 MG; HS; PO. Patient died on 05/01/2007.
Temozolomide Side Effects Report #5519647-4
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 07, 2007. Male patient, 44 years of age, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: blood pressure increased, cholelithiasis, glioblastoma multiforme, hyperglycaemia, malignant neoplasm progression, pancreatitis acute. Temozolomide dosage: 50 MG/M2;QD;PO ; 50 MG/M2;QD;PO. During the same period patient was treated with BEVACIZUMAB, HYDROCHLOROTHIAZIDE, NEXIUM, XANAX. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5573913-5
Temozolomide side effect was reported by a Physician from UNITED STATES on Dec 13, 2007. Male patient, 39 years of age, weighting 141.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, glioblastoma multiforme, malignant neoplasm progression, oliguria. Temozolomide dosage: 50 MG/M2; PO; PO, ; PO. During the same period patient was treated with BEVACIZUMAB, LEXAPRO, KEPPRA, DEPAKOTE ER, LORAZEPAM, GABAPENTIN. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5137070-1
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 26, 2006. Male patient, weighting 137.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: convulsion, deep vein thrombosis
, headache , hemiplegia, malignant neoplasm progression, nervous system disorder. Temozolomide dosage: 135 MG. Patient recovered.Temozolomide Side Effects Report #5980945-1
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 02, 2008. Female patient, weighting 142.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: glioblastoma multiforme, malignant neoplasm progression. Temozolomide dosage: 85MG DAILY X 28 DAYS PO. During the same period patient was treated with BEVACIZUMAB, DEXAMETHASONE, KEPPRA, ZANTAC, LISINOPRIL. Patient died on 12/01/2008.
Temozolomide Side Effects Report #4831332-0
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Nov 16, 2005. Male patient, weighting 201.5 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: deep vein thrombosis
, malignant neoplasm progression, oedema peripheral. Temozolomide dosage: 420 MG PO DAILY X 5 DAYS Q 28 DAYS. During the same period patient was treated with TOPOTECAN, TRILEPTAL, ZANTAC. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5663902-4
Temozolomide side effect was reported by a Physician from ISRAEL on Mar 03, 2008. Male patient, 67 years of age, weighting 167.6 lb, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: convulsion, glioblastoma, malignant neoplasm progression, sepsis
, thrombocytopenia. Temozolomide dosage: QD;PO, 190 QD;PO, 140 MG. During the same period patient was treated with CONVERTIN, GLUCOPHAGE, GLIBETIC, EPANUTIN. Patient died on 11/24/2007.Temozolomide Side Effects Report #5397278-7
Temozolomide side effect was reported by a Physician from GERMANY on July 19, 2007. Male patient, 65 years of age, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: glioblastoma multiforme, malignant neoplasm progression, partial seizures, respiratory failure, status epilepticus. Temozolomide dosage: 75 MG/M2; 200 MG/M2; 200 MG/M2; 200 MG/M2;. Patient was hospitalized. Patient died on 05/07/2007.
Temozolomide Side Effects Report #5504575-0
Temozolomide side effect was reported by a Physician from GERMANY on Oct 25, 2007. Male patient, 63 years of age, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: ataxia
, glioblastoma, malignant neoplasm progression, neurogenic bladder, pneumococcal sepsis, somnolence, urinary tract infection . Temozolomide dosage: unknown. During the same period patient was treated with DOXORUBICIN HYDROCHLORIDE, CORTIZONE. Patient was hospitalized. Patient died on 05/17/2005.Temozolomide Side Effects Report #5248608-8
Temozolomide side effect was reported by a Physician from GERMANY on Feb 16, 2007. Male patient, 69 years of age, weighting 172.0 lb, was diagnosed with anaplastic astrocytoma, glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anaplastic astrocytoma, glioblastoma, malignant neoplasm progression. Temozolomide dosage: 400 MG;QD. During the same period patient was treated with FRISIUM, NEURONTIN. Patient died.
Temozolomide Side Effects Report #4645500-4
Temozolomide side effect was reported by a Physician from on Apr 14, 2005. Female patient, 44 years of age, was diagnosed with anaplastic astrocytoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: acute leukaemia, anaplastic astrocytoma, bone marrow depression, febrile neutropenia, malignant neoplasm progression, myelodysplastic syndrome, pancytopenia, refractory anaemia with an excess of blasts. Temozolomide dosage: unknown. Patient died.
Temozolomide Side Effects Report #5758691-9
Temozolomide side effect was reported by a Health Professional from UNITED STATES on June 03, 2008. Female patient, weighting 118.2 lb, was diagnosed with acute myeloid leukaemia and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, atrial fibrillation
, cardio-respiratory arrest, malignant neoplasm progression, renal infarct, splenic infarction, thrombocytopenia. Temozolomide dosage: 100 MG/M2 (160 MG) QD PO. During the same period patient was treated with ATIVAN, HALDOL, ACETAMINOPHEN, HYDROXYPROPYL METHYLCELLULOSE, SALIVA SUBSTITUTE, ATROPINE, GLYCOPYRROLATE. Patient died on 06/01/2008.Temozolomide Side Effects Report #5763464-7
Temozolomide side effect was reported by a Health Professional from UNITED STATES on June 04, 2008. Female patient, weighting 118.2 lb, was diagnosed with acute myeloid leukaemia and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abdominal pain
, atrial fibrillation , cardio-respiratory arrest, embolism, lethargy, leukostasis, lung infection, malignant neoplasm progression, no therapeutic response. Temozolomide dosage: 100 MG/M2 (160 MG) QD PO. During the same period patient was treated with ATIVAN, HALDOL, ACETAMINOPHEN, HYDROXYPROPYL METHYLCELLULOSE, SALIVA SUBSTITUTE ORAL SOLUTION, ATROPINE, GLYCOPYRROLATE. Patient died on 05/31/2008.Temozolomide Side Effects Report #4744650-1
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 12, 2005. Male patient, 54 years of age, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: decreased appetite, fatigue, malignant neoplasm progression, nausea
, necrosis, oral intake reduced, radiation injury. Temozolomide dosage: unknown. During the same period patient was treated with IRINOTECAN. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5224677-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 29, 2007. Female patient, weighting 151.5 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorectal cellulitis, aplastic anaemia, bone marrow failure, febrile neutropenia, glioblastoma multiforme, haemorrhoids, malignant neoplasm progression, thrombocytopenia. Temozolomide dosage: 3640 MG. During the same period patient was treated with BACTRIM, DEXAMETHASONE, KEPPRA, QVC HERBS AND SUPPLEMENTS. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5146229-9
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 06, 2006. Female patient, weighting 151.5 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorectal cellulitis, aplastic anaemia, bone marrow failure, febrile neutropenia, glioblastoma multiforme, haemorrhoids, malignant neoplasm progression, thrombocytopenia. Temozolomide dosage: 3640 MG. During the same period patient was treated with BACTRIM, DEXAMETHASONE, KEPPRA. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5162374-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 27, 2006. Female patient, weighting 151.5 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorectal cellulitis, aplastic anaemia, bone marrow failure, febrile neutropenia, glioblastoma multiforme, haemorrhoids, malignant neoplasm progression, thrombocytopenia. Temozolomide dosage: 3640 MG. During the same period patient was treated with BACTRIM, DEXAMETHASONE, KEPPRA. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5523033-0
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 16, 2007. Female patient, weighting 151.5 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: aplastic anaemia, bone marrow failure, cellulitis
, haemorrhoids, lymphopenia, malignant neoplasm progression, proctalgia. Temozolomide dosage: 3640 MG. During the same period patient was treated with BACTRIM, DEXAMETHASONE, KEPPRA, OVC HERBS AND SUPPLEMENTS. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5530432-X
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 27, 2007. Female patient, weighting 194.0 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, candidiasis, cushing's syndrome, glioblastoma multiforme, lymphopenia, malignant neoplasm progression. Temozolomide dosage: 1450 MG. During the same period patient was treated with BACTRIM DS, DECADRON, KEPPRA. Patient was hospitalized. Patient recovered.
Temozolomide Side Effects Report #5591135-9
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Jan 10, 2008. Female patient, weighting 134.3 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: dizziness
, glioblastoma, malignant neoplasm progression, tremor. Temozolomide dosage: 5720 MG. During the same period patient was treated with DECADRON. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5637985-1
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 22, 2008. Male patient, weighting 225.3 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abdominal pain
, convulsion, glioblastoma multiforme, malignant neoplasm progression, procedural complication, pulmonary embolism , status epilepticus. Temozolomide dosage: 4620 MG. Patient was hospitalized. Patient recovered.Temozolomide Side Effects Report #5695827-2
Temozolomide side effect was reported by a Physician from ISRAEL on Apr 04, 2008. Male patient, weighting 167.6 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: convulsion, glioblastoma, malignant neoplasm progression, motor dysfunction, nervous system disorder, organ failure, sepsis
. Temozolomide dosage: 570 MG. Patient recovered.Temozolomide Side Effects Report #5893258-3
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 22, 2008. Male patient, weighting 226.2 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: lymphopenia, malignant neoplasm progression. Temozolomide dosage: 2250 MG. Patient recovered.