Temozolomide and disease progression Patient Reports February 11, 2012

Temozolomide Side Effects Report #6090653-7
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Feb 15, 2009. Male patient, 41 years of age, weighting 170.2 lb, was diagnosed with neoplasm malignant and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, confusional state, disease progression, dyspnoea. Temozolomide dosage: 400 MG; QD; PO. During the same period patient was treated with VELCADE, DEXAMETHASONE, METHADONE, HYDROMORPHONE, MIRALAX, SENNA. Patient was hospitalized. Patient died on 12/15/2008.

Temozolomide Side Effects Report #5593400-8
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Jan 07, 2008. Male patient, 72 years of age, weighting 146.2 lb, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: activities of daily living impaired, alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, diastolic dysfunction, disease progression, dyspnoea, malaise. Temozolomide dosage: 280 MG. During the same period patient was treated with RIFATEX. Patient was hospitalized and became disabled. Patient recovered.

Temozolomide Side Effects Report #5804220-0
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on June 26, 2008. Male patient, 72 years of age, weighting 146.2 lb, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abdominal discomfort, alanine aminotransferase increased, anorexia, aspartate aminotransferase increased, blood lactate dehydrogenase increased, diastolic dysfunction, dilatation atrial, disease progression, dyspnoea. Temozolomide dosage: 280 MG. During the same period patient was treated with RIFATEX. Patient was hospitalized and became disabled. Patient recovered.

Temozolomide Side Effects Report #5723129-4
Temozolomide side effect was reported by a Physician from SWITZERLAND on Apr 18, 2008. Female patient, 63 years of age, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, infection , liver disorder. Temozolomide dosage: 240 MG; PO. During the same period patient was treated with BEVACIZUMAB. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #5563304-5
Temozolomide side effect was reported by a Physician from GERMANY on Nov 30, 2007. Female patient, 59 years of age, weighting 119.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, pancreatitis, x-ray gastrointestinal tract abnormal. Temozolomide dosage: 185 MG;. During the same period patient was treated with PANTOPRAZOLE, NORMOFUNDIN, FRAXIPARIN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5892297-6
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Sept 11, 2008. Male patient, 36 years of age, weighting 253.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, cough, decreased appetite, disease progression, failure to thrive, metastases to lung, nausea , oxygen saturation decreased, weight decreased. Temozolomide dosage: 100 MG; QD; PO, 60 MG; QD, PO, 15 MG; QD; PO. During the same period patient was treated with DECITABINE, OXYCONTIN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5118514-8
Temozolomide side effect was reported by a Physician from UNITED STATES on Sept 20, 2006. Male patient, 30 years of age, weighting 258.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anaemia haemolytic autoimmune, bone marrow failure, disease progression, ecchymosis, erythema, haematoma, pancytopenia, pyrexia, skin lesion. Temozolomide dosage: 360 MG;. During the same period patient was treated with ZOFRAN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5525162-4
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 13, 2007. Male patient, 66 years of age, was diagnosed with metastases to central nervous system and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anaemia, confusional state, disease progression, malaise, nausea . Temozolomide dosage: unknown. Patient died on 10/21/2007.

Temozolomide Side Effects Report #5345437-1
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on May 16, 2007. Female patient, 50 years of age, weighting 112.4 lb, was diagnosed with malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, disease progression, fall , thrombocytopenia. Temozolomide dosage: unknown. During the same period patient was treated with INTRON A, METOCLOPRAMIDE, ONDANSETRON. Patient was hospitalized. Patient died on 12/01/1998.


Temozolomide Side Effects Report #5519103-3
Temozolomide side effect was reported by a Physician from BRAZIL on Nov 08, 2007. Male patient, 47 years of age, weighting 185.2 lb, was diagnosed with malignant melanoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression. Temozolomide dosage: 300 MG;. Patient was hospitalized. Patient died on 09/13/2007.

Temozolomide Side Effects Report #5320858-1
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Apr 25, 2007. Male patient, 68 years of age, weighting 242.5 lb, was diagnosed with malignant glioma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: balance disorder, body temperature increased, confusional state, convulsion, disease progression, neutrophil count abnormal, oral intake reduced, platelet count decreased. Temozolomide dosage: 235 MG; QD; PO. During the same period patient was treated with DEXAMETHASONE, CARBAMAZEPINE. Patient was hospitalized. Patient died on 12/07/2006.

Temozolomide Side Effects Report #5957773-6
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 11, 2008. Male patient, 68 years of age, was diagnosed with malignant glioma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: dehydration, disease progression, fall , gait disturbance, haemorrhage. Temozolomide dosage: unknown. Patient was hospitalized. Patient died on 10/05/2008.

Temozolomide Side Effects Report #5978147-8
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 24, 2008. Male patient, 68 years of age, was diagnosed with malignant glioma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: dehydration, disease progression, fall , gait disturbance, intracranial tumour haemorrhage. Temozolomide dosage: unknown. Patient was hospitalized. Patient died on 10/05/2008.

Temozolomide Side Effects Report #5223602-1
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Jan 17, 2007. Male patient, 63 years of age, was diagnosed with malignant glioma, recurrent cancer and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: convulsion, disease progression, ill-defined disorder, infection , lower respiratory tract infection, platelet count decreased. Temozolomide dosage: 200 MG; QD; PO. During the same period patient was treated with PROCARBAZINE, VINCRISTINE. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #5530347-7
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Nov 27, 2007. Male patient, 57 years of age, weighting 220.5 lb, was diagnosed with gliosarcoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, dyspnoea, lethargy. Temozolomide dosage: 80MG/M2 PO DAILY. During the same period patient was treated with BEVACIZUMAB, LOTREL, LEXAPRO, DECADRON, MINOCYCLINE, ZOCOR, IMODIUM. Patient died on 09/17/2007.

Temozolomide Side Effects Report #5422609-9
Temozolomide side effect was reported by a Physician from UNITED STATES on Aug 10, 2007. Female patient, 79 years of age, weighting 157.6 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: atrial fibrillation , bone marrow failure, disease progression, pancytopenia, sick sinus syndrome. Temozolomide dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO; 200 MG/M2; QD; PO. Patient died on 07/15/2007.

Temozolomide Side Effects Report #5324186-X
Temozolomide side effect was reported by a Physician from ISRAEL on Apr 27, 2007. Male patient, 76 years of age, weighting 167.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: bacterial infection , confusional state, conjunctivitis, depressed level of consciousness, disease progression, meningitis viral, pyrexia, viral infection , vitreous detachment. Temozolomide dosage: 140 MG; QD; PO. During the same period patient was treated with DEXAMETHASONE, INSULIN, NORMITEN. Patient was hospitalized. Patient died on 03/10/2007.

Temozolomide Side Effects Report #5538349-1
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 29, 2007. Male patient, 75 years of age, weighting 153.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: brain oedema, confusional state, depressed level of consciousness, disease progression, infection , intestinal obstruction. Temozolomide dosage: 75 MG/M2; QD; PO. During the same period patient was treated with KEPPRA, RISPERDAL. Patient was hospitalized. Patient died on 11/21/2007.

Temozolomide Side Effects Report #5229077-0
Temozolomide side effect was reported by a Physician from UNITED STATES on Jan 24, 2007. Female patient, 74 years of age, weighting 135.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorexia, atelectasis, disease progression, hyperglycaemia, hypoalbuminaemia, muscular weakness. Temozolomide dosage: 125 MG; QD; PO. During the same period patient was treated with RADIATION, ZIAC, PROTONIX, AVANDIA, PRANDIN, PHENYTOIN, BACTRIM, XOPENEX. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #5242592-9
Temozolomide side effect was reported by a Physician from UNITED STATES on Feb 07, 2007. Female patient, 74 years of age, weighting 135.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorexia, atelectasis, cognitive disorder, disease progression, dysphagia, haemoglobin decreased, hemiparesis, herpes zoster. Temozolomide dosage: 125 MG;QD; PO. During the same period patient was treated with RADIATION, ZIAC, PROTONIX, AVANDIA, PRANDIN, PHENYTOIN, BACTRIM, XOPONEX. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5257049-9
Temozolomide side effect was reported by a Physician from UNITED STATES on Feb 26, 2007. Female patient, 74 years of age, weighting 135.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorexia, aphagia, atelectasis, cognitive disorder, disease progression, haemoglobin decreased, hemiparesis, herpes zoster. Temozolomide dosage: 125 MG;QD;PO. During the same period patient was treated with RADIATION, ZIAC, PROTONIX, AVANDIA, PRANDIN, PHENYTOIN, BACTRIM, XOPENEX. Patient was hospitalized. Patient died on 02/12/2007.

Temozolomide Side Effects Report #5225097-0
Temozolomide side effect was reported by a Physician from JAPAN on Jan 23, 2007. Male patient, 66 years of age, weighting 103.6 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, gastric cancer stage ii, gastric ulcer, pyloric stenosis, reflux oesophagitis. Temozolomide dosage: 75 MG/M2; QD; PO, SEE IMAGE. During the same period patient was treated with NASEA OD. Patient recovered.

Temozolomide Side Effects Report #5694089-X
Temozolomide side effect was reported by a Physician from UNITED STATES on Mar 24, 2008. Male patient, 52 years of age, weighting 192.4 lb, was diagnosed with glioblastoma multiforme, antifungal prophylaxis and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abasia, chest x-ray abnormal, cholelithiasis, confusional state, disease progression, gait disturbance, hepatitis , hypotension. Temozolomide dosage: 75 MG/M2; PO. During the same period patient was treated with PENTAMIDINE ISETHIONATE, NEURONTIN, PEPCID, ZOFRAN, TYLENOL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5353174-2
Temozolomide side effect was reported by a Health Professional from UNITED STATES on June 01, 2007. Male patient, 51 years of age, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression. Temozolomide dosage: 120 MG;HS;PO. Patient died on 05/01/2007.


Temozolomide Side Effects Report #5525159-4
Temozolomide side effect was reported by a Physician from UNITED STATES on Nov 09, 2007. Male patient, 44 years of age, weighting 242.5 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abdominal pain , abdominal pain upper, cholelithiasis, disease progression, hyperglycaemia, hypertension, nausea , pancreatitis acute. Temozolomide dosage: 50 MG/M2; QD; PO, 50 MG/M2; QD; PO. During the same period patient was treated with BEVACIZUMAB, HYDROCHLOROTHIAZIDE, NEXIUM, XANAX. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5530499-9
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Nov 27, 2007. Male patient, 37 years of age, weighting 167.6 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abasia, activities of daily living impaired, disease progression, glioblastoma, pancytopenia, post procedural haemorrhage, recurrent cancer. Temozolomide dosage: 50MG/M2 PO DAILY. During the same period patient was treated with BEVACIZUMAB, LOVENOX, NEXIUM, RITALIN, KEPPRA, DEPAKOTE, DEXAMETHASONE, TESTOSTERONE. Patient died on 10/08/2007.

Temozolomide Side Effects Report #5988997-X
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 09, 2008. Male patient, weighting 141.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, disease progression, neuropathy peripheral. Temozolomide dosage: 85MG DAILY X 28 DAYS PO. During the same period patient was treated with BEVACIZUMAB, LAMICTAL, KEPPRA, VALTREX, COLACE, METAMUCIL, DECADRON, LISINOPRIL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #4752194-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 24, 2005. Male patient, weighting 211.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abasia, asthenia, condition aggravated, convulsion, deep vein thrombosis , difficulty in walking, disease progression, disorientation, fatigue. Temozolomide dosage: unknown. During the same period patient was treated with IRINOTECAN, RADIATION, LISINOPRIL, PEPCID, PRAVACHOL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #4752255-1
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 23, 2005. Male patient, weighting 211.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abasia, asthenia, convulsion, deep vein thrombosis , disease progression, disorientation, fatigue, headache . Temozolomide dosage: unknown. During the same period patient was treated with RADIATION, IRINOTECAN, LISINOPRIL, PEPCID. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #4991344-3
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on May 01, 2006. Female patient, weighting 217.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, dysphagia, neurological symptom, vomiting. Temozolomide dosage: 150 MG. Patient was hospitalized. Patient died.

Temozolomide Side Effects Report #5656217-1
Temozolomide side effect was reported by a Physician from GERMANY on Feb 27, 2008. Female patient, 75 years of age, weighting 156.5 lb, was diagnosed with glioblastoma, glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: brain oedema, confusional state, disease progression, disorientation, increased appetite, neutropenia, pneumonia , thrombocytopenia. Temozolomide dosage: 130 MG; QD; PO. During the same period patient was treated with DEXAMETHASONE, CONTRIMTE, L THYROXIN, REMERGIL, TAVOR, RISPERDAL. Patient was hospitalized. Patient died on 02/10/2008.

Temozolomide Side Effects Report #5669985-X
Temozolomide side effect was reported by a Physician from GERMANY on Mar 04, 2008. Female patient, 75 years of age, weighting 156.5 lb, was diagnosed with glioblastoma, glioblastoma multiforme and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: apathy, brain oedema, confusional state, disease progression, neutropenia, pneumonia , pyrexia, thrombocytopenia. Temozolomide dosage: 130 MG; QD; PO. During the same period patient was treated with DEXAMETHASONE, CONTRIMTE, L THYROXIN, REMERGIL, TAVOR, RISPERDAL. Patient was hospitalized. Patient died on 02/10/2008.

Temozolomide Side Effects Report #5454994-6
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Sept 03, 2007. Male patient, 63 years of age, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, pancytopenia. Temozolomide dosage: 75 MG/M2; PO. During the same period patient was treated with DEXAMETHASONE, OMEPRAZOLE. Patient was hospitalized and became disabled. Patient died.

Temozolomide Side Effects Report #5834944-0
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on July 29, 2008. Male patient, 63 years of age, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, pancytopenia. Temozolomide dosage: 75 MG/M2; PO. During the same period patient was treated with DEXAMETHASONE, OMEPRAZOLE. Patient was hospitalized and became disabled. Patient died.


Temozolomide Side Effects Report #4715620-4
Temozolomide side effect was reported by a Physician from SOUTH AFRICA on July 05, 2005. Male patient, 46 years of age, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, pneumonia primary atypical, pneumonitis. Temozolomide dosage: unknown. Patient recovered.

Temozolomide Side Effects Report #5920399-4
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Oct 03, 2008. Female patient, 29 years of age, weighting 165.3 lb, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: central nervous system infection, culture positive, device related infection, disease progression, enterobacter infection, escherichia infection, intraventricular haemorrhage, leukopenia, medical device complication. Temozolomide dosage: unknown. During the same period patient was treated with TEGRETOL, GABAPENTIN, OMEPRAZOLE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5070165-X
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Aug 02, 2006. Male patient was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, pancytopenia. Temozolomide dosage: PO 360 MG (DAY1) 45MG (. During the same period patient was treated with ADVAIR DISCUS, DECADRON, PREVACID, TEGRETOL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5401832-3
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on July 18, 2007. Male patient was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, pancytopenia. Temozolomide dosage: 75 MG;. Patient died.

Temozolomide Side Effects Report #5474120-7
Temozolomide side effect was reported by a Health Professional from UNITED STATES on Sept 27, 2007. Male patient, weighting 154.3 lb, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: deep vein thrombosis , disease progression. Temozolomide dosage: PO 140MG (DAY1). During the same period patient was treated with EFFEXOR, PEPCID, DEXAMETHASONE, POTASSIUM CHLORIDE, KEPPRA, TRAZODONE, PROVIGIL. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #6030767-0
Temozolomide side effect was reported by a Physician from SPAIN on Dec 23, 2008. Male patient, weighting 185.2 lb, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: abdominal pain , bacteria urine, disease progression, febrile neutropenia, gastritis, hemiparesis, thrombocytopenia, vomiting. Temozolomide dosage: 35 MG;Q8H;PO. During the same period patient was treated with DEXAMETHASONE, IRINOTECAN, OMEPRAZOLE, ONDANSETRON. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #6050192-6
Temozolomide side effect was reported by a Physician from SPAIN on Jan 13, 2009. Male patient, weighting 185.2 lb, was diagnosed with glioblastoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: bacteria urine identified, disease progression, febrile neutropenia, gastritis, glioblastoma, hemiparesis, hypokinesia, thrombocytopenia. Temozolomide dosage: 35 MG;Q8H;PO. During the same period patient was treated with DEXAMETHASONE POSPHATE, IRINOTECAN, OMEPRAZOLE, ONDASETRON. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5528398-1
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Nov 14, 2007. Male patient, 61 years of age, weighting 149.9 lb, was diagnosed with gastrointestinal carcinoma, malignant respiratory tract neoplasm and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: atrial fibrillation , disease progression, pulmonary oedema. Temozolomide dosage: 270 MG; QD; PO. During the same period patient was treated with LOSEC, PENICILLIN G, DEXAMETHASONE, ORAMORPH, NUROFEN. Patient was hospitalized. Patient died on 11/05/2007.

Temozolomide Side Effects Report #5714320-1
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Apr 11, 2008. Male patient, 60 years of age, weighting 177.0 lb, was diagnosed with colorectal cancer metastatic and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, haemoptysis, metastases to lung, pulmonary haemorrhage. Temozolomide dosage: 300 MG;QD;PO. During the same period patient was treated with ATENOLOL, AMLODIPINE, ASPIRIN, BENDROFLUAZIDE, LANSOPRAZOLE, SIMVASTATIN, PERINDOPRIL ERBUMINE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5632265-2
Temozolomide side effect was reported by a Physician from UNITED KINGDOM on Feb 06, 2008. Female patient, 71 years of age, weighting 96.34 lb, was diagnosed with colorectal cancer  and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression. Temozolomide dosage: 210 MG; QD; PO. Patient died on 11/05/2007.

Temozolomide Side Effects Report #5725128-5
Temozolomide side effect was reported by a Physician from on Apr 22, 2008. Male patient, 46 years of age, weighting 206.6 lb, was diagnosed with colorectal cancer  and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, dehydration, disease progression, dizziness , renal impairment, vomiting. Temozolomide dosage: 250 MG; QD; PO, 250 MG; QD; PO. During the same period patient was treated with GABAPENTIN, OLANZAPINE, VENLAFAXINE, TRAMADOL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5730341-7
Temozolomide side effect was reported by a Physician from MEXICO on Apr 29, 2008. Male patient, 46 years of age, weighting 206.6 lb, was diagnosed with colorectal cancer  and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, dehydration, disease progression, dizziness , refusal of treatment by patient, renal impairment, vomiting. Temozolomide dosage: 250 MG; QD; PO; 250 MG; QD; PO. During the same period patient was treated with GABAPENTIN, OLANZAPINE, VENLAFAXINE, TRAMADOL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5733176-4
Temozolomide side effect was reported by a Physician from MEXICO on May 05, 2008. Male patient, 46 years of age, weighting 206.6 lb, was diagnosed with colorectal cancer  and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, blood creatine increased, blood glucose increased, blood urea increased, dehydration, disease progression, dizziness , renal function test abnormal, vomiting. Temozolomide dosage: 250 MG, QD, PO. During the same period patient was treated with GABAPENTIN, OLANZAPINE, VENLAFAXINE, TRAMADOL. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #6010134-6
Temozolomide side effect was reported by a Physician from MEXICO on Dec 10, 2008. Male patient, 46 years of age, weighting 206.6 lb, was diagnosed with colorectal cancer  and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, blood creatinine increased, blood urea increased, dehydration, disease progression, dizziness , vomiting. Temozolomide dosage: 250 MG; QD; PO. During the same period patient was treated with GABAPENTIN, OLANZAPINE, VENLAFAZINE, TRAMADOL. Patient was hospitalized. Patient died on 07/18/2008.

Temozolomide Side Effects Report #5756584-4
Temozolomide side effect was reported by a Physician from UNITED STATES on May 16, 2008. Female patient, 61 years of age, weighting 172.2 lb, was diagnosed with colon cancer metastatic and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorexia, bacteraemia, blood culture positive, decreased appetite, disease progression, nausea , pain , pyrexia, staphylococcal infection . Temozolomide dosage: unknown. During the same period patient was treated with ALBUTEROL, LOVENOX, METOPROLOL, NORCO, ZOFRAN, COMPAZINE. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #5757973-4
Temozolomide side effect was reported by a Physician from UNITED STATES on May 22, 2008. Female patient, 61 years of age, weighting 172.2 lb, was diagnosed with colon cancer metastatic and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anorexia, arthralgia, decreased appetite, dehydration, disease progression, hypotension, nausea , pain , peripheral sensory neuropathy. Temozolomide dosage: 270 MG; QD; PO. During the same period patient was treated with ALBUTEROL, LOVENOX, METOPROLOL, NORCO, ZOFRAN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #6136316-0
Temozolomide side effect was reported by a Physician from UNITED STATES on Mar 16, 2009. Female patient, 49 years of age, was diagnosed with breast cancer metastatic and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: chest pain , constipation , decreased appetite, dehydration, disease progression, dyspnoea, flatulence, headache , hypoaesthesia. Temozolomide dosage: 250 MG;. During the same period patient was treated with TOPOTECAN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #4642184-6
Temozolomide side effect was reported by a Physician from on Apr 21, 2005. Male patient, weighting 50.93 lb, was diagnosed with brain stem glioma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: coordination abnormal, cough, depressed level of consciousness, disease progression, drooling, dysphagia, dyspnoea, headache , heart rate increased. Temozolomide dosage: 85 MG PO Q DAY. During the same period patient was treated with DECADRON. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5321375-5
Temozolomide side effect was reported by a Physician from UNITED STATES on Apr 25, 2007. Male patient, 59 years of age, weighting 233.7 lb, was diagnosed with astrocytoma, low grade and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, cerebrovascular accident, confusional state, convulsion, coordination abnormal, disease progression, encephalomalacia, haemorrhage, hydrocephalus . Temozolomide dosage: unknown. During the same period patient was treated with AVASTIN. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5836205-2
Temozolomide side effect was reported by a Physician from UNITED STATES on July 30, 2008. Male patient, 33 years of age, was diagnosed with anaplastic astrocytoma and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: balance disorder, blood creatinine increased, blood culture positive, confusional state, deafness unilateral, diplopia, disease progression, disorientation, dizziness . Temozolomide dosage: 200 MG/M2; QD; PO,; PO. During the same period patient was treated with DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5001706-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on May 12, 2006. Female patient, weighting 89.95 lb, was diagnosed with acute myeloid leukaemia and was treated with Temozolomide. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, disease progression. Temozolomide dosage: 1600 MG. Patient died.

Temozolomide Side Effects Report #5311092-X
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Apr 27, 2007. Male patient, weighting 233.7 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anaplastic astrocytoma, asthenia, cerebrovascular accident, confusional state, convulsion, coordination abnormal, disease progression, encephalomalacia, haemorrhage. Temozolomide dosage: 13410 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5324955-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on May 10, 2007. Female patient, weighting 167.6 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, dizziness , incoherent. Temozolomide dosage: 5940 MG. Patient was hospitalized. Patient died on 03/02/2007.

Temozolomide Side Effects Report #5109863-8
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 18, 2006. Male patient, weighting 200.4 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, platelet count decreased. Temozolomide dosage: 155 MG. Patient was hospitalized. Patient died on 09/01/2006.

Temozolomide Side Effects Report #5411940-9
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 10, 2007. Male patient, weighting 192.4 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: brain oedema, confusional state, convulsion, disease progression, postictal state, radiation injury, somnolence, tremor. Temozolomide dosage: 150 MG. During the same period patient was treated with HERBAL AGENTS. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #5411941-0
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 10, 2007. Male patient, weighting 192.4 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: brain oedema, confusional state, convulsion, disease progression, postictal state, radiation injury, somnolence, tremor. Temozolomide dosage: 150 MG. During the same period patient was treated with HERBAL AGENTS. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5416467-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 13, 2007. Female patient, weighting 157.6 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: bone marrow failure, disease progression, transfusion reaction. Temozolomide dosage: 1900 MG. Patient died on 07/15/2007.

Temozolomide Side Effects Report #5476984-X
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 03, 2007. Male patient, weighting 218.3 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: confusional state, disease progression, gait disturbance, hemiparesis, vision blurred. Temozolomide dosage: 3465 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5483842-3
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 09, 2007. Male patient, weighting 170.9 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: central nervous system neoplasm, disease progression, disease recurrence, necrosis, neutrophil count abnormal, oedema, platelet count abnormal, radiation injury, white blood cell count abnormal. Temozolomide dosage: 2050 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5490440-4
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Oct 17, 2007. Female patient, weighting 207.2 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: brain neoplasm, disease progression, necrosis, neutrophil count decreased, platelet count decreased, radiation injury, white blood cell count decreased. Temozolomide dosage: 2050 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5509756-8
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 07, 2007. Female patient, weighting 194.0 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: asthenia, candidiasis, cushing's syndrome, disease progression, glioblastoma multiforme, lymphopenia. Temozolomide dosage: 1450 MG. During the same period patient was treated with BACTRIM DS, DECADRON, KEPPRA. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5533316-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 29, 2007. Female patient, weighting 107.8 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: brain oedema, confusional state, disease progression, fall , speech disorder. Temozolomide dosage: 1100 MG. During the same period patient was treated with DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5534054-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 29, 2007. Female patient, weighting 156.6 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: candidiasis, disease progression, herpes zoster, nausea , neutrophil count decreased, platelet count decreased, white blood cell count decreased. Temozolomide dosage: 5320 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5534055-8
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Nov 29, 2007. Male patient, weighting 143.3 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: confusional state, disease progression, disorientation. Temozolomide dosage: 270 MG. During the same period patient was treated with STEROID. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5648018-5
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Feb 29, 2008. Female patient, weighting 157.6 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: bone marrow failure, disease progression, transfusion reaction. Temozolomide dosage: 1900 MG. Patient died on 07/15/2007.


Temozolomide Side Effects Report #5650468-8
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 04, 2008. Male patient, weighting 167.6 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: condition aggravated, convulsion, disease progression, glioblastoma, motor dysfunction, sepsis , thrombocytopenia. Temozolomide dosage: 570 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5657256-7
Temozolomide side effect was reported by a Physician from GERMANY on Mar 07, 2008. Female patient, weighting 156.5 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: apathy, brain oedema, confusional state, disease progression, disorientation, neutropenia, pain , pyrexia. Temozolomide dosage: 910 MG. During the same period patient was treated with FORTECORIN. Patient was hospitalized. Patient died on 02/10/2008.

Temozolomide Side Effects Report #5730212-6
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on May 05, 2008. Female patient, weighting 117.7 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, glaucoma , headache , hemiparesis, nausea , nervous system disorder, oedema, radiation injury. Temozolomide dosage: 4830 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5786101-4
Temozolomide side effect was reported by a Physician from ISRAEL on June 20, 2008. Male patient, weighting 167.6 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: convulsion, disease progression, feeling hot, organ failure, platelet count decreased, sepsis . Temozolomide dosage: 570 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5818926-0
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on July 21, 2008. Male patient, weighting 188.0 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: arrhythmia , disease progression, fall , gait disturbance, gastrointestinal haemorrhage, hip fracture, post procedural complication, postoperative renal failure, procedural hypotension. Temozolomide dosage: unknown. Patient was hospitalized. Patient died on 07/15/2008.

Temozolomide Side Effects Report #5871841-9
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Sept 04, 2008. Female patient, weighting 122.1 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, leukopenia, pneumonia . Temozolomide dosage: 4920 MG. Patient was hospitalized. Patient died on 06/19/2006.

Temozolomide Side Effects Report #5934248-1
Temozolomide side effect was reported by a Consumer or non-health professional from SWITZERLAND on Oct 28, 2008. Female patient, weighting 228.2 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: brain compression, brain oedema, c-reactive protein increased, disease progression, electroencephalogram abnormal, fall , fatigue, neoplasm progression, partial seizures. Temozolomide dosage: 4640 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #5948015-6
Temozolomide side effect was reported by a Physician from ISRAEL on Nov 10, 2008. Male patient, weighting 167.6 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: anaemia, convulsion, disease progression, leukopenia, organ failure, sepsis , thrombocytopenia. Temozolomide dosage: 570 MG. Patient recovered.

Temozolomide Side Effects Report #5962735-9
Temozolomide side effect was reported by a Consumer or non-health professional from CANADA on Nov 19, 2008. Male patient, weighting 156.3 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: bacterial sepsis, disease progression, enterocolitis, feeling abnormal, intestinal ischaemia, loss of consciousness, mental status changes, performance status decreased. Temozolomide dosage: 3640 MG. Patient was hospitalized. Patient died on 06/28/2008.

Temozolomide Side Effects Report #5983784-0
Temozolomide side effect was reported by a Physician from SWITZERLAND on Dec 05, 2008. Female patient, weighting 134.9 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: aphasia , brain oedema, central nervous system lesion, disease progression, motor dysfunction. Temozolomide dosage: 3360 MG. Patient was hospitalized. Patient recovered.


Temozolomide Side Effects Report #6013554-9
Temozolomide side effect was reported by a Consumer or non-health professional from SWITZERLAND on Dec 18, 2008. Female patient, weighting 134.9 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: aphasia , cranial neuropathy, disease progression, motor neurone disease, oedema, speech disorder. Temozolomide dosage: 3360 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #6105158-4
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 04, 2009. Female patient, weighting 140.0 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: cd4 lymphocytes decreased, disease progression. Temozolomide dosage: 165 MG. Patient was hospitalized. Patient recovered.

Temozolomide Side Effects Report #4650589-2
Temozolomide side effect was reported by a Consumer or non-health professional from on Apr 29, 2005. Male patient, weighting 53.79 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, dysphagia, dyspnoea, loss of consciousness, oral intake reduced, posturing, speech disorder, unresponsive to verbal stimuli. Temozolomide dosage: 90 MG/M2/DAY (85 MG PER DAY). Patient recovered.

Temozolomide Side Effects Report #5032555-0
Temozolomide side effect was reported by a Consumer or non-health professional from UNITED STATES on June 21, 2006. Female patient, weighting 122.1 lb, was treated with Temozolomide. After drug was administered, patient experienced the following side effects: disease progression, leukopenia, pneumonia , pyrexia. Temozolomide dosage: 4920 MG. Patient was hospitalized. Patient died on 06/19/2006.