Temodar and dyspnoea Patient Reports February 11, 2012

Temodar Side Effects Report #5508496-9
Temodar side effect was reported by a Health Professional from UNITED STATES on Oct 31, 2007. Male patient, 79 years of age, weighting 154.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, dyspnoea, neutrophil count abnormal, oral herpes, pneumonia mycoplasmal, pyrexia, respiratory failure. Temodar dosage: 300 MG; QD; PO. During the same period patient was treated with THALIMIDE, TAGAMET, MIRALAX. Patient was hospitalized. Patient died on 10/18/2007.

Temodar Side Effects Report #5388900-X
Temodar side effect was reported by a Health Professional from UNITED STATES on July 13, 2007. Female patient, weighting 237.0 lb, was diagnosed with metastases to central nervous system and was treated with Temodar. After drug was administered, patient experienced the following side effects: dyspnoea, glioblastoma multiforme, nausea , presyncope, pulmonary embolism . Temodar dosage: unknown. During the same period patient was treated with PROCARDIA, VICODIN ES, ZOCOR, NITRO, LOPRESSOR, VOLTAREN, FLEXERIL. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5201893-0
Temodar side effect was reported by a Physician from UNITED STATES on Nov 16, 2005. Female patient, 77 years of age, weighting 119.0 lb, was diagnosed with malignant melanoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: disease progression, dyspnoea, fatigue, pancytopenia, urinary tract infection . Temodar dosage: 220 MG QD ORAL. During the same period patient was treated with ZOFRAN, LEVOTHYROXINE, GLUCOSAMINE, CENTRUM, CALCIUM. Patient was hospitalized. Patient died on 02/01/2006.

Temodar Side Effects Report #4641736-7
Temodar side effect was reported by a Physician from on Apr 11, 2005. Female patient, 47 years of age, was diagnosed with haemangiopericytoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: dyspnoea, neutropenia, septic shock. Temodar dosage: 100MG 5D/WK ORAL. Patient was hospitalized. Patient died on 02/18/2005.


Temodar Side Effects Report #5819987-5
Temodar side effect was reported by a Physician from UNITED STATES on July 16, 2008. Male patient, 62 years of age, was diagnosed with glioma and was treated with Temodar. After drug was administered, patient experienced the following side effects: asthenia, cough, disease progression, dyspnoea, pneumonia , pyrexia, sepsis , syncope. Temodar dosage: 140 MG; PO. During the same period patient was treated with DEXAMETHASONE, PRILOSEC, KYTRIL, SEPTRA DS, ACETAMINOPHEN, ALBUTEROL, ALUMINUM HYDROXIDE. Patient was hospitalized. Patient died on 12/07/2007.

Temodar Side Effects Report #4910444-7
Temodar side effect was reported by a Physician from UNITED STATES on Jan 31, 2006. Female patient, 56 years of age, was diagnosed with glioma and was treated with Temodar. After drug was administered, patient experienced the following side effects: dyspnoea, headache , hypoventilation, lethargy, nausea . Temodar dosage: 150 MG/M^2 ORAL. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5422608-7
Temodar side effect was reported by a Physician from UNITED STATES on Aug 10, 2007. Female patient, 79 years of age, weighting 173.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, atrial fibrillation , bone marrow failure, dyspnoea, nodal arrhythmia, palpitations, pancytopenia, sick sinus syndrome, urinary tract infection . Temodar dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with VITAMIN CAP. Patient was hospitalized. Patient died on 07/15/2007.

Temodar Side Effects Report #5428479-7
Temodar side effect was reported by a Physician from UNITED STATES on Aug 22, 2007. Female patient, 79 years of age, weighting 173.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, atrial fibrillation , bone marrow failure, dyspnoea, nodal arrhythmia, palpitations, pancytopenia, sick sinus syndrome, urinary tract infection . Temodar dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with VITAMIN CAP. Patient was hospitalized. Patient died on 07/15/2007.

Temodar Side Effects Report #5331669-5
Temodar side effect was reported by a Physician from UNITED STATES on May 11, 2007. Male patient, 72 years of age, weighting 257.5 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: asthenia, cerebral haemorrhage, diarrhoea, dyspnoea, lung infiltration, melaena, musculoskeletal pain, neutrophil count decreased, oedema peripheral. Temodar dosage: 170 MG; QD; PO. During the same period patient was treated with HUMALOG, LASIX, ZOCOR, COZAAR, GLUCOPHAGE, ADVIL. Patient was hospitalized. Patient died on 05/02/2007.


Temodar Side Effects Report #5973895-8
Temodar side effect was reported by a Physician from UNITED STATES on Nov 14, 2008. Male patient, 66 years of age, weighting 250.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: asthenia, dyspnoea, hyperhidrosis, lactic acidosis, supraventricular extrasystoles, supraventricular tachycardia. Temodar dosage: unknown. During the same period patient was treated with KEPPRA, DECADRON. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5974359-8
Temodar side effect was reported by a Physician from UNITED STATES on Nov 21, 2008. Male patient, 66 years of age, weighting 250.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: arrhythmia , asthenia, dyspnoea, hyperhidrosis, intracranial pressure increased, lactic acidosis, left ventricular dysfunction, supraventricular extrasystoles, supraventricular tachycardia. Temodar dosage: unknown. During the same period patient was treated with KEPPRA, DECADRON. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #4580066-9
Temodar side effect was reported by a Physician from on Feb 01, 2005. Male patient, 66 years of age, weighting 197.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: asthenia, dyspnoea, glioblastoma multiforme, influenza like illness, malignant neoplasm progression, movement disorder , pyrexia. Temodar dosage: 400 MG QDX5D ORAL. During the same period patient was treated with DECADRON, TEGRETOL, ZANTAC, ENALAPRIL. Patient died on 09/29/2004.

Temodar Side Effects Report #5527188-3
Temodar side effect was reported by a Physician from UNITED STATES on Nov 15, 2007. Female patient, 63 years of age, weighting 217.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: dyspnoea, platelet count decreased. Temodar dosage: unknown. Patient was hospitalized. Patient died on 11/08/2007.

Temodar Side Effects Report #5645997-7
Temodar side effect was reported by a Physician from UNITED STATES on Feb 19, 2008. Female patient, 63 years of age, weighting 217.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: disease progression, dyspnoea, febrile neutropenia, mental status changes, platelet count decreased. Temodar dosage: unknown. Patient was hospitalized. Patient died on 11/08/2007.


Temodar Side Effects Report #4718747-6
Temodar side effect was reported by a Physician from UNITED STATES on July 08, 2005. Male patient, 50 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, blood pressure decreased, dialysis , dyspnoea, hepatic enzyme increased, hypoxia, malaise, multi-organ failure, nausea . Temodar dosage: 150MG QD; ORAL. During the same period patient was treated with GLIOBLASTOMAME, LAMICTAL, ALLEGRA, BACTRIM TIW. Patient was hospitalized. Patient died on 05/27/2005.

Temodar Side Effects Report #5494550-7
Temodar side effect was reported by a Physician from UNITED STATES on Oct 16, 2007. Male patient, weighting 264.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: cough, dyspnoea, nausea . Temodar dosage: 75 MG/M2; QD; PO. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5534984-5
Temodar side effect was reported by a Physician from UNITED STATES on Nov 28, 2007. Male patient, weighting 195.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: aortic valve incompetence, arrhythmia , atrial fibrillation , cardiac failure congestive, chronic obstructive pulmonary disease, condition aggravated, dyspnoea, ejection fraction decreased, hyperglycaemia. Temodar dosage: 155 MG;QD;PO. Patient was hospitalized. Patient died on 11/05/2007.

Temodar Side Effects Report #4687477-1
Temodar side effect was reported by a Consumer or non-health professional from on June 09, 2005. Female patient, weighting 137.8 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: dyspnoea, pulmonary embolism . Temodar dosage: 75 MG/M2. During the same period patient was treated with CPT, RADIATION. Patient recovered.

Temodar Side Effects Report #4712849-6
Temodar side effect was reported by a Consumer or non-health professional from UNITED STATES on July 12, 2005. Female patient, weighting 153.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: convulsion, cough, dyspnoea, interstitial lung disease, leukopenia, lymphopenia, pneumocystis jiroveci pneumonia, pulmonary oedema, pyrexia. Temodar dosage: unknown. During the same period patient was treated with RADITIATION. Patient recovered.


Temodar Side Effects Report #6105711-8
Temodar side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 04, 2009. Male patient, 26 years of age, weighting 407.9 lb, was diagnosed with glioblastoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: dysphagia, dyspnoea, epiglottitis, haemoglobin decreased, respiratory tract infection. Temodar dosage: 590MG PO X 5 DAYS Q28. During the same period patient was treated with TOPOTECAN, PROTONIX, KEPPRA, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5730970-0
Temodar side effect was reported by a Physician from UNITED STATES on Apr 28, 2008. Male patient, 79 years of age, weighting 200.6 lb, was diagnosed with acute myeloid leukaemia and was treated with Temodar. After drug was administered, patient experienced the following side effects: blood creatinine increased, blood urea increased, cardiac arrest , cardiovascular disorder, disseminated intravascular coagulation, dyspnoea, fungal oesophagitis, hyperkalaemia. Temodar dosage: 100 MG/M2; QD; PO; 200 MG/M2; QD; PO. During the same period patient was treated with ENALAPRIL MALEATE, PROTONIX, ACTOS, PRAVASTATIN, DILTIAZEM, PREDNISONE, OXYGEN. Patient was hospitalized. Patient died on 04/26/2008.

Temodar Side Effects Report #5761923-4
Temodar side effect was reported by a Physician from UNITED STATES on May 27, 2008. Female patient, 79 years of age, weighting 118.2 lb, was diagnosed with acute myeloid leukaemia and was treated with Temodar. After drug was administered, patient experienced the following side effects: abdominal pain upper, blood sodium decreased, diarrhoea, dyspnoea, hyperhidrosis, nausea , night sweats, petechiae, platelet count decreased. Temodar dosage: 160 MG; QD; PO, 320 MG; QD; PO. During the same period patient was treated with LISINOPRIL, CIPRO, FLAGYL. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5836207-6
Temodar side effect was reported by a Physician from UNITED STATES on July 28, 2008. Male patient, 77 years of age, weighting 205.0 lb, was diagnosed with acute myeloid leukaemia and was treated with Temodar. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, asthenia, cardiomegaly, dyspnoea, febrile neutropenia, haematocrit decreased, haemoglobin decreased, malignant neoplasm progression, no therapeutic response. Temodar dosage: 100 MG/M2; QD; PO, 420 MG; QD; PO. During the same period patient was treated with COREG, OMEPRAZOLE, AVODART, VYTORIN, ALLOPURINOL. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5860595-8
Temodar side effect was reported by a Health Professional from UNITED STATES on Aug 18, 2008. Male patient, 77 years of age, weighting 205.0 lb, was treated with Temodar. After drug was administered, patient experienced the following side effects: acute myeloid leukaemia, cardiomegaly, dyspnoea, febrile neutropenia, hyperhidrosis, infection , malignant neoplasm progression, oedema peripheral. Temodar dosage: 100 MG/M2;QD; PO; 420 ;PO. During the same period patient was treated with COREG, OMEPRAZOLE, AVODART, VYTORIN, ALLOPURINOL. Patient was hospitalized. Patient recovered.


Temodar Side Effects Report #5883722-5
Temodar side effect was reported by a Physician from UNITED STATES on Sept 05, 2008. Female patient was treated with Temodar. After drug was administered, patient experienced the following side effects: asthenia, dyspnoea, oedema, palpitations, thrombosis. Temodar dosage: unknown. Patient recovered.

Temodar Side Effects Report #4636485-5
Temodar side effect was reported by a Consumer or non-health professional from on Apr 14, 2005. Female patient, weighting 209.4 lb, was treated with Temodar. After drug was administered, patient experienced the following side effects: chest pain , dyspnoea. Temodar dosage: unknown. During the same period patient was treated with IRINOTECAN. Patient recovered.