Temodar and diarrhoea Patient Reports February 11, 2012

Temodar Side Effects Report #6122092-4
Temodar side effect was reported by a Consumer or non-health professional from UNITED STATES on Mar 16, 2009. Female patient, 48 years of age, weighting 149.9 lb, was diagnosed with oligodendroglioma and was treated with Temodar. After drug was administered, patient experienced the following side effects: brain neoplasm, brain oedema, diarrhoea, febrile neutropenia, mental status changes, neoplasm progression, pancytopenia. Temodar dosage: 350MG PO X 5 DAYS Q28. During the same period patient was treated with TOPOTECAN, TEGRETOL, KEFLEX, ZOFRAN. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #6130549-5
Temodar side effect was reported by a Physician from UNITED STATES on Mar 13, 2009. Female patient, 48 years of age, was diagnosed with oligodendroglioma and was treated with Temodar. After drug was administered, patient experienced the following side effects: brain oedema, diarrhoea, disease progression, febrile neutropenia, mental status changes, pancytopenia. Temodar dosage: 350 MG; PO. During the same period patient was treated with TOPOTECAN, TEGRETOL, KEFLEX, ZOFRAN. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5861065-3
Temodar side effect was reported by a Physician from UNITED STATES on Aug 14, 2008. Female patient, 61 years of age, weighting 120.0 lb, was diagnosed with neuroendocrine tumour, off label use, prophylaxis and was treated with Temodar. After drug was administered, patient experienced the following side effects: acute sinusitis, aplastic anaemia, atrial septal defect, blood glucose increased, blood potassium decreased, constipation , coronary artery disease , diarrhoea, disease progression. Temodar dosage: 220 MG; QD; PO. During the same period patient was treated with BACTRIM DS, BENICAR, NEXIUM, TOPROL, ACTONEL, CALCIUM, VITAMIN D. Patient recovered.

Temodar Side Effects Report #4606933-5
Temodar side effect was reported by a Physician from on Feb 28, 2005. Male patient, 69 years of age, weighting 185.2 lb, was diagnosed with neuroendocrine carcinoma, neuroendocrine tumour and was treated with Temodar. After drug was administered, patient experienced the following side effects: asthenia, cd4 lymphocytes decreased, cd8 lymphocytes decreased, cytomegalovirus colitis, cytomegalovirus infection , diarrhoea, eating disorder , herpes zoster, lip pain. Temodar dosage: 150 MG/M2 ORAL. During the same period patient was treated with THALIDOMIDE, DOXORUBICIN, OCTREOTIDE, ZOFRAN. Patient was hospitalized. Patient died on 09/01/2004.


Temodar Side Effects Report #5199996-2
Temodar side effect was reported by a Health Professional from UNITED STATES on Dec 21, 2006. Female patient, 77 years of age, weighting 218.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: anorexia, asthenia, colitis, condition aggravated, dehydration, diarrhoea, diverticulum intestinal, dry mouth, fatigue. Temodar dosage: 315 MG; QOW; PO; SEE IMAGE. During the same period patient was treated with SUTENT, SKELAXIN, DIOVAN, CLARINEX. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5209188-6
Temodar side effect was reported by a Health Professional from UNITED STATES on Jan 03, 2007. Female patient, 77 years of age, weighting 218.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: anorexia, asthenia, colitis, condition aggravated, dehydration, diarrhoea, diverticulum intestinal, dry mouth, fatigue. Temodar dosage: unknown. During the same period patient was treated with SUTENT, SKELAXIN, DIOVAN, CLARINEX, MOBIC. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5084298-5
Temodar side effect was reported by a Health Professional from UNITED STATES on Aug 08, 2006. Female patient, 77 years of age, weighting 218.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: anorexia, asthenia, colitis, dehydration, diarrhoea, diverticulum intestinal, dry mouth, fatigue, hypovolaemia. Temodar dosage: 315MGQDX7Q ORAL. During the same period patient was treated with SUNITINIB MALATE, SKELAXIN, DIOVAN, CLARINEX, MOBIC, NEXIUM, INDAPAMIDE, PEPCID. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5130527-9
Temodar side effect was reported by a Health Professional from UNITED STATES on Oct 09, 2006. Female patient, 77 years of age, weighting 218.0 lb, was diagnosed with metastatic malignant melanoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: anorexia, asthenia, colitis, condition aggravated, dehydration, diarrhoea, diverticulum intestinal, dry mouth, fatigue. Temodar dosage: unknown. During the same period patient was treated with SUTENT, SKELAXIN, DIOVAN, CLARINEX, MOBIC. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #4947931-1
Temodar side effect was reported by a Health Professional from UNITED STATES on Mar 17, 2006. Female patient, weighting 249.1 lb, was diagnosed with malignant oligodendroglioma and was treated with Temodar. After drug was administered, patient experienced the following side effects: diarrhoea, fatigue, malignant neoplasm progression, malignant oligodendroglioma, nausea , viral infection . Temodar dosage: 470MG PO QD FOR 5 DAYS. During the same period patient was treated with GLEEVEC, DECADRON SRC, KEPPRA, ZOCOR, LEXAPRO, PROTONIX. Patient was hospitalized. Patient recovered.


Temodar Side Effects Report #5521521-4
Temodar side effect was reported by a Health Professional from UNITED STATES on Nov 16, 2007. Female patient, weighting 129.0 lb, was diagnosed with malignant melanoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: abdominal pain , diarrhoea, disease recurrence, diverticulitis, nausea , pancytopenia. Temodar dosage: unknown. During the same period patient was treated with SUTENT, ZOFRAN, LOTREL, METAMUCIL. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5331669-5
Temodar side effect was reported by a Physician from UNITED STATES on May 11, 2007. Male patient, 72 years of age, weighting 257.5 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: asthenia, cerebral haemorrhage, diarrhoea, dyspnoea, lung infiltration, melaena, musculoskeletal pain, neutrophil count decreased, oedema peripheral. Temodar dosage: 170 MG; QD; PO. During the same period patient was treated with HUMALOG, LASIX, ZOCOR, COZAAR, GLUCOPHAGE, ADVIL. Patient was hospitalized. Patient died on 05/02/2007.

Temodar Side Effects Report #5618933-7
Temodar side effect was reported by a Physician from UNITED STATES on Feb 01, 2008. Female patient, 71 years of age, weighting 121.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, gastroenteritis viral, hypomagnesaemia, hyponatraemia, hypotension, mental disorder, renal failure acute, vomiting. Temodar dosage: 115 MG; QD; PO. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5662383-4
Temodar side effect was reported by a Physician from UNITED STATES on Feb 29, 2008. Female patient, 71 years of age, weighting 121.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, gastroenteritis viral, hypomagnesaemia, hyponatraemia, hypotension, lymphopenia, renal failure acute, vomiting. Temodar dosage: 115 MG; QD; PO. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5725814-7
Temodar side effect was reported by a Physician from UNITED STATES on Apr 24, 2008. Female patient, 71 years of age, weighting 121.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: dehydration, diarrhoea, gastroenteritis viral, hypomagnesaemia, hyponatraemia, hypotension, lymphopenia, renal failure acute, vomiting. Temodar dosage: 115 MG;QD;PO. Patient was hospitalized. Patient recovered.


Temodar Side Effects Report #5414758-6
Temodar side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 08, 2007. Male patient, 68 years of age, weighting 218.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: adrenal insufficiency, arrhythmia supraventricular, asthenia, atrial fibrillation , dehydration, diarrhoea, hyperglycaemia, hypotension, neutropenia. Temodar dosage: 200 MG/M2;QD;PO. During the same period patient was treated with IRINOTECAN, COUMADIN, LOTREL, LASIX, TOPROL, DECADRON SRC, LIPITOR. Patient was hospitalized. Patient died on 08/02/2007.

Temodar Side Effects Report #5933431-9
Temodar side effect was reported by a Physician from UNITED STATES on Oct 17, 2008. Male patient, 68 years of age, weighting 218.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: adrenal insufficiency, arrhythmia supraventricular, atrial fibrillation , coronary artery disease , dehydration, diarrhoea, hyperglycaemia, hypotension, neutropenia. Temodar dosage: 200 MG/M2;QD;PO. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, IRINOTECAN HYDROCHLORIDE, COUMADIN, LOTREL, LASIX, TOPROL, LIPITOR, DECADRON. Patient was hospitalized. Patient died on 08/02/2007.

Temodar Side Effects Report #5957774-8
Temodar side effect was reported by a Physician from UNITED STATES on Nov 11, 2008. Male patient, 68 years of age, weighting 218.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: adrenal insufficiency, arrhythmia supraventricular, atrial fibrillation , clostridial infection, dehydration, diarrhoea, hyperglycaemia, pancytopenia, renal failure acute. Temodar dosage: 200 MG/M2;QD;PO. During the same period patient was treated with IRINOTECAN HYDROCHLORIDE, IRINOTECAN HYDROCHLORIDE, DECADRON, COUMADIN, LOTREL, LASIX, TOPROL, LIPITOR. Patient was hospitalized. Patient died on 08/02/2007.

Temodar Side Effects Report #5135844-4
Temodar side effect was reported by a Physician from UNITED STATES on Oct 06, 2006. Male patient, 53 years of age, weighting 160.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: acne , alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, bone marrow failure, confusional state, diarrhoea, disease progression, incorrect dose administered. Temodar dosage: 2750 MG; QD; PO. Patient was hospitalized. Patient died on 09/10/2005.

Temodar Side Effects Report #5508511-2
Temodar side effect was reported by a Physician from UNITED STATES on Oct 31, 2007. Female patient, 52 years of age, weighting 173.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: abdominal discomfort, chest discomfort, decreased appetite, diabetic ketoacidosis, diarrhoea, disease recurrence, dizziness , febrile neutropenia, herpes zoster. Temodar dosage: 140 MG; QD; PO. During the same period patient was treated with BACTRIM DS, DEXAMETHASONE. Patient was hospitalized. Patient recovered.


Temodar Side Effects Report #4688647-9
Temodar side effect was reported by a Consumer or non-health professional from on June 10, 2005. Female patient, weighting 205.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: asthenia, diarrhoea, difficulty in walking, dizziness , fall , haemoglobin decreased, headache , hypothyroidism, infection . Temodar dosage: 75 MG/M2 PO X 6 WEEKS DURING RT, FOLLOWED BY 150 MG/M2/DAY PO DAYS 1-5 Q 28 DAYS. During the same period patient was treated with RADIATION. Patient recovered.

Temodar Side Effects Report #5761923-4
Temodar side effect was reported by a Physician from UNITED STATES on May 27, 2008. Female patient, 79 years of age, weighting 118.2 lb, was diagnosed with acute myeloid leukaemia and was treated with Temodar. After drug was administered, patient experienced the following side effects: abdominal pain upper, blood sodium decreased, diarrhoea, dyspnoea, hyperhidrosis, nausea , night sweats, petechiae, platelet count decreased. Temodar dosage: 160 MG; QD; PO, 320 MG; QD; PO. During the same period patient was treated with LISINOPRIL, CIPRO, FLAGYL. Patient was hospitalized. Patient recovered.

Temodar Side Effects Report #5765897-1
Temodar side effect was reported by a Physician from UNITED STATES on June 02, 2008. Female patient, 79 years of age, weighting 118.2 lb, was diagnosed with acute myeloid leukaemia and was treated with Temodar. After drug was administered, patient experienced the following side effects: abdominal pain , atelectasis, coagulopathy, diarrhoea, diverticulum, effusion, hepatosplenomegaly, hyponatraemia, infection . Temodar dosage: 160 MG; QD; PO, 320 MG; QD; PO. During the same period patient was treated with LISINOPRIL, CIPRO, FLAGYL. Patient was hospitalized. Patient recovered.