Temodar and bone marrow failure 
Temodar and bone marrow failure Patient Reports February 11, 2012
Temodar Side Effects Report #5201882-6
Temodar side effect was reported by a Physician from UNITED STATES on Aug 15, 2005. Female patient, 42 years of age, was diagnosed with metastatic malignant melanoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: 150 MG/M^2 ORAL; 1 CYCLE (S). During the same period patient was treated with DILANTIN. Patient recovered.
Temodar Side Effects Report #5422608-7
Temodar side effect was reported by a Physician from UNITED STATES on Aug 10, 2007. Female patient, 79 years of age, weighting 173.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, atrial fibrillation
, bone marrow failure, dyspnoea, nodal arrhythmia, palpitations, pancytopenia, sick sinus syndrome, urinary tract infection . Temodar dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with VITAMIN CAP. Patient was hospitalized. Patient died on 07/15/2007.Temodar Side Effects Report #5428479-7
Temodar side effect was reported by a Physician from UNITED STATES on Aug 22, 2007. Female patient, 79 years of age, weighting 173.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, atrial fibrillation
, bone marrow failure, dyspnoea, nodal arrhythmia, palpitations, pancytopenia, sick sinus syndrome, urinary tract infection . Temodar dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with VITAMIN CAP. Patient was hospitalized. Patient died on 07/15/2007.Temodar Side Effects Report #5651812-8
Temodar side effect was reported by a Physician from UNITED STATES on Feb 25, 2008. Female patient, 79 years of age, weighting 173.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: arrhythmia supraventricular, atrial fibrillation
, bone marrow failure, sick sinus syndrome, urinary tract infection . Temodar dosage: 75 MG/M2;QD;PO; 150 MG/M2;QD;PO;200 MG/M2;QD;PO. During the same period patient was treated with VITAMIN CAP. Patient was hospitalized. Patient died on 07/15/2007.Temodar Side Effects Report #5945759-7
Temodar side effect was reported by a Physician from UNITED STATES on Nov 03, 2008. Female patient, 76 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: aplasia, aspergilloma, bone marrow failure, neutropenia, pancytopenia. Temodar dosage: 75 MG/M2;PO. During the same period patient was treated with ZOLOFT, DECADRON, SYNTHROID, AMBIEN, NORVASC. Patient died on 09/01/2008.
Temodar Side Effects Report #5663503-8
Temodar side effect was reported by a Physician from UNITED STATES on Mar 03, 2008. Male patient, 75 years of age, weighting 146.6 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure, fatigue, idiopathic thrombocytopenic purpura. Temodar dosage: 130 MG; QD; PO. During the same period patient was treated with DILANTIN, FAMOTIDINE, DECADRON. Patient was hospitalized. Patient recovered.
Temodar Side Effects Report #4792044-5
Temodar side effect was reported by a Health Professional from UNITED STATES on Sept 26, 2005. Female patient, 67 years of age, weighting 154.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, decubitus ulcer, deep vein thrombosis
, diabetes mellitus non-insulin-dependent, ecchymosis, febrile neutropenia, fluid retention, herpes simplex . Temodar dosage: 140 MG QD ORAL. During the same period patient was treated with LASIX, KEPPRA, PROTONIX, POTASSIUM CHLORIDE, GLUCOPHAGE, DECADRON, TYLENOL, METOCLOPRAMIDE. Patient was hospitalized. Patient recovered.Temodar Side Effects Report #5756939-8
Temodar side effect was reported by a Physician from UNITED STATES on May 23, 2008. Female patient, 59 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: blood creatinine increased, bone marrow failure, dehydration, febrile neutropenia, hyperglycaemia, hypokalaemia, hypophosphataemia, oxygen saturation decreased, pancytopenia. Temodar dosage: 130 MG;QD;PO. During the same period patient was treated with TRILEPTAL, DECADRON, PERCOCET, NIZORAL, ENJUVIA, ZOFRAN. Patient was hospitalized. Patient died on 05/17/2008.
Temodar Side Effects Report #5776004-3
Temodar side effect was reported by a Consumer or non-health professional from UNITED STATES on June 10, 2008. Female patient, 59 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: blood culture positive, blood pressure decreased, bone marrow failure, dehydration, febrile neutropenia, heart rate increased, hyperglycaemia, hypokalaemia. Temodar dosage: 130 MG; QD; PO. During the same period patient was treated with TRILEPTAL, DECADRON, PERCOCET, NIZORAL, ENJUVIA, ZOFRAN, PROTONIX, NYSTATIN. Patient was hospitalized. Patient died on 05/17/2008.
Temodar Side Effects Report #6030858-4
Temodar side effect was reported by a Consumer or non-health professional from UNITED STATES on Dec 24, 2008. Female patient, 59 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: bacteroides infection, blood culture positive, bone marrow failure, candidiasis, escherichia infection, febrile neutropenia, platelet count decreased, staphylococcal infection
, white blood cell count decreased. Temodar dosage: unknown. During the same period patient was treated with VITAMIN K, IMIPENEM, VANCOMYCIN HYDROCHLORIDE, NEUPOGEN, DECADRON, PROTONIX, INSULIN, ALBUTEROL. Patient was hospitalized. Patient died on 05/17/2008.Temodar Side Effects Report #5135844-4
Temodar side effect was reported by a Physician from UNITED STATES on Oct 06, 2006. Male patient, 53 years of age, weighting 160.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: acne
, alanine aminotransferase increased, aspartate aminotransferase increased, blood alkaline phosphatase increased, bone marrow failure, confusional state, diarrhoea, disease progression, incorrect dose administered. Temodar dosage: 2750 MG; QD; PO. Patient was hospitalized. Patient died on 09/10/2005.Temodar Side Effects Report #5232620-9
Temodar side effect was reported by a Physician from UNITED STATES on Jan 29, 2007. Female patient, 47 years of age, weighting 151.5 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: anorectal cellulitis, aplastic anaemia, bone marrow failure, febrile neutropenia, glioblastoma multiforme, haemorrhoids, leukopenia, malignant neoplasm progression, thrombocytopenia. Temodar dosage: 75 MG/M2; QD; PO. During the same period patient was treated with BACTRIM DS, DEXAMETHASONE, KEPPRA, PREMPRO, ZOFRAN, RUTOVIT C, LYCOPENE. Patient was hospitalized. Patient recovered.
Temodar Side Effects Report #5483531-5
Temodar side effect was reported by a Physician from UNITED STATES on Oct 04, 2007. Female patient, 47 years of age, weighting 151.5 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: aplastic anaemia, bone marrow failure, cellulitis
, febrile neutropenia, haemorrhoids, lymphopenia, thrombocytopenia, white blood cell count decreased. Temodar dosage: 75 MG/M2; QD; PO. During the same period patient was treated with BACTRIM DS, DEXAMETHASONE, KEPPRA, PREMPRO, ZOFRAN, RUTOVIT C, LYCOPENE. Patient was hospitalized. Patient recovered.Temodar Side Effects Report #5140512-9
Temodar side effect was reported by a Physician from UNITED STATES on Oct 11, 2006. Male patient, 45 years of age, weighting 162.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure, lymphocyte count decreased, neutrophil count decreased, pneumocystis jiroveci pneumonia. Temodar dosage: unknown. During the same period patient was treated with CELECOXIB, ACCUTANE. Patient was hospitalized. Patient died on 09/22/2006.
Temodar Side Effects Report #5028155-9
Temodar side effect was reported by a Physician from UNITED STATES on May 31, 2006. Male patient, 45 years of age, weighting 165.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: aplastic anaemia, bone marrow failure, cytomegalovirus viraemia, malaise, myelitis transverse, pancytopenia, paraplegia, weight decreased. Temodar dosage: unknown. During the same period patient was treated with DILANTIN, TEGRETOL, PEPCID, ATIVAN, ZOFRAN. Patient was hospitalized. Patient died.
Temodar Side Effects Report #4796431-0
Temodar side effect was reported by a Physician from UNITED STATES on Aug 24, 2004. Male patient, 40 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: 65 MG/M2 ORAL, 2 CYCLE(S). Patient recovered.
Temodar Side Effects Report #5201886-3
Temodar side effect was reported by a Health Professional from UNITED STATES on Aug 24, 2005. Female patient was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: unknown. Patient recovered.
Temodar Side Effects Report #4830504-9
Temodar side effect was reported by a Health Professional from UNITED STATES on Nov 02, 2005. Male patient was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure, contusion, full blood count decreased, haemorrhage, incorrect dose administered, pneumonia
, renal failure. Temodar dosage: 140-180MG QD ORAL; 140 MG QD ORAL; 140 MG QD ORAL; 180 MG QD ORAL. Patient was hospitalized. Patient died on 09/03/2005.Temodar Side Effects Report #4861020-6
Temodar side effect was reported by a Health Professional from UNITED STATES on Dec 07, 2005. Male patient was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: abasia, activities of daily living impaired, bone marrow failure, contusion, lymphocyte count decreased, platelet count decreased, pneumonia
, puncture site haemorrhage. Temodar dosage: 140-180MG* QD ORAL. Patient was hospitalized. Patient died on 09/03/2005.Temodar Side Effects Report #4881920-0
Temodar side effect was reported by a Health Professional from UNITED STATES on Jan 03, 2006. Male patient, weighting 170.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: abasia, activities of daily living impaired, asthenia, bone marrow failure, contusion, incorrect dose administered, pneumonia
, post procedural haemorrhage. Temodar dosage: unknown. Patient was hospitalized. Patient died on 09/03/2005.Temodar Side Effects Report #4896245-7
Temodar side effect was reported by a Health Professional from UNITED STATES on Jan 18, 2006. Male patient, weighting 170.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: abasia, activities of daily living impaired, asthenia, bone marrow failure, contusion, haemorrhage, pneumonia
, renal failure. Temodar dosage: 140-180MG* QD ORAL. Patient was hospitalized. Patient died on 09/03/2005.Temodar Side Effects Report #5066726-4
Temodar side effect was reported by a Physician from UNITED STATES on July 18, 2006. Female patient, 74 years of age, was diagnosed with glioblastoma, glioblastoma multiforme and was treated with Temodar. After drug was administered, patient experienced the following side effects: aplastic anaemia, atrial fibrillation
, bone marrow failure, escherichia infection, hypotension, hypoventilation, hypoxia, ischaemic hepatitis, liver function test abnormal. Temodar dosage: 75 MG/M2 ORAL. Patient was hospitalized. Patient recovered.Temodar Side Effects Report #5720669-9
Temodar side effect was reported by a Physician from UNITED STATES on Apr 17, 2008. Male patient, 34 years of age, was diagnosed with glioblastoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: aplastic anaemia, bone marrow failure, epistaxis, pancytopenia, petechiae, pneumonia fungal. Temodar dosage: 140 MG;QD;PO. During the same period patient was treated with BACTRIM DS, DEXAMETHASONE, KEPPRA, PROMETHAZINE, ZOLOFT. Patient was hospitalized. Patient recovered.
Temodar Side Effects Report #5933992-X
Temodar side effect was reported by a Physician from UNITED STATES on Oct 12, 2007. Male patient, 22 years of age, was diagnosed with brain neoplasm and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: unknown. Patient recovered.
Temodar Side Effects Report #5326894-3
Temodar side effect was reported by a Physician from IRELAND on May 02, 2007. Male patient was diagnosed with brain neoplasm and was treated with Temodar. After drug was administered, patient experienced the following side effects: blood bilirubin increased, bone marrow failure, hepatotoxicity, immunosuppression, liver function test abnormal, pneumonia
. Temodar dosage: 75 MG;. Patient was hospitalized. Patient died.Temodar Side Effects Report #5494145-5
Temodar side effect was reported by a Physician from UNITED STATES on Oct 12, 2007. Male patient was diagnosed with brain neoplasm and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure, petechiae. Temodar dosage: unknown. Patient recovered.
Temodar Side Effects Report #5950967-5
Temodar side effect was reported by a Physician from UNITED STATES on Nov 03, 2008. Male patient, 52 years of age, weighting 205.0 lb, was diagnosed with astrocytoma, gout
and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure, nephrolithiasis. Temodar dosage: 140 MG;QD;PO. During the same period patient was treated with ALLOPURINOL, KEPPRA, PROTONIX, DILANTIN, TOPROL, LIPITOR, ASPIRIN. Patient was hospitalized and became disabled. Patient died on 10/02/2006.Temodar Side Effects Report #5621639-1
Temodar side effect was reported by a Physician from UNITED STATES on Feb 01, 2008. Female patient, 78 years of age, weighting 189.0 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure, pancytopenia. Temodar dosage: 140 MG; QD; PO. Patient died on 12/26/2007.
Temodar Side Effects Report #5201883-8
Temodar side effect was reported by a Health Professional from UNITED STATES on Aug 24, 2005. Female patient was diagnosed with anaplastic astrocytoma and was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: unknown. Patient recovered.
Temodar Side Effects Report #4796476-0
Temodar side effect was reported by a Physician from UNITED STATES on June 29, 2005. Female patient, 50 years of age, was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: unknown. Patient was hospitalized. Patient recovered.
Temodar Side Effects Report #5914461-X
Temodar side effect was reported by a Physician from UNITED STATES on Oct 02, 2008. Female patient was treated with Temodar. After drug was administered, patient experienced the following side effects: aspergilloma, bone marrow failure. Temodar dosage: unknown. Patient died on 09/01/2008.
Temodar Side Effects Report #4796470-X
Temodar side effect was reported by a Health Professional from UNITED STATES on May 10, 2005. Male patient was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: unknown. Patient recovered.
Temodar Side Effects Report #4928885-0
Temodar side effect was reported by a Physician from UNITED STATES on Feb 14, 2006. Male patient was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: 75MG/M^2 ORAL. Patient died on 01/01/2006.
Temodar Side Effects Report #4957365-1
Temodar side effect was reported by a Physician from UNITED STATES on Mar 22, 2006. Male patient was treated with Temodar. After drug was administered, patient experienced the following side effects: bone marrow failure. Temodar dosage: 75MG/M^2 ORAL. Patient died on 01/01/2006.