Temodal and respiratory failure Patient Reports February 12, 2012

Temodal Side Effects Report #5919053-4
Temodal side effect was reported by a Physician from JAPAN on Oct 06, 2008. Male patient, 63 years of age, weighting 156.5 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: convulsion, myelodysplastic syndrome, neoplasm progression, pneumonia , respiratory failure. Temodal dosage: unknown. During the same period patient was treated with DEPAKENE, TEGRETOL. Patient was hospitalized. Patient died on 11/27/2007.

Temodal Side Effects Report #4765606-9
Temodal side effect was reported by a Physician from FRANCE on Aug 26, 2005. Male patient was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: bronchiolitis, infection , no therapeutic response, respiratory failure. Temodal dosage: unknown. During the same period patient was treated with NATULAN CAPSULES. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #6123728-4
Temodal side effect was reported by a Physician from SPAIN on Mar 11, 2009. Female patient, 57 years of age, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: pancytopenia, respiratory failure. Temodal dosage: unknown. During the same period patient was treated with DEXAMETHASONE, PRIMPERAN, SEGURIL, SEPTRINTE, ZOFRAN. Patient died on 08/29/2007.

Temodal Side Effects Report #4776976-X
Temodal side effect was reported by a Physician from FRANCE on Sept 06, 2005. Male patient, 33 years of age, was diagnosed with malignant oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: bronchiolitis, respiratory failure. Temodal dosage: unknown. During the same period patient was treated with NATULAN. Patient was hospitalized. Patient recovered.


Temodal Side Effects Report #5811044-7
Temodal side effect was reported by a Consumer or non-health professional from JAPAN on July 07, 2008. Male patient, 59 years of age, weighting 110.2 lb, was diagnosed with malignant glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: cough, interstitial lung disease, respiratory failure. Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with NASEA, ALEVIATIN, MAGNESIUM OXIDE. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5429885-7
Temodal side effect was reported by a Physician from FRANCE on Aug 22, 2007. Female patient, 74 years of age, weighting 152.1 lb, was diagnosed with lymphoma  and was treated with Temodal. After drug was administered, patient experienced the following side effects: haematotoxicity, hypotension, respiratory failure, septic shock. Temodal dosage: 270 MG; QD; PO. During the same period patient was treated with METHOTREXATE. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5122750-4
Temodal side effect was reported by a Physician from GERMANY on Sept 08, 2006. Female patient, 75 years of age, weighting 132.3 lb, was diagnosed with gliosarcoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: cardiac failure, pancytopenia, pleural effusion, pneumonia , respiratory failure, subileus. Temodal dosage: 75 MG/M2; PO. Patient was hospitalized. Patient died on 09/09/2005.

Temodal Side Effects Report #4788290-7
Temodal side effect was reported by a Physician from GERMANY on Sept 23, 2005. Female patient, 75 years of age, weighting 132.3 lb, was diagnosed with gliosarcoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: cardiac failure, lung infiltration, pancytopenia, pleural effusion, pneumonia , respiratory failure, subileus. Temodal dosage: 75 MG/M^2 ORAL. Patient was hospitalized. Patient died on 09/09/2005.

Temodal Side Effects Report #5323105-X
Temodal side effect was reported by a Pharmacist from UNITED KINGDOM on Apr 10, 2007. Female patient, child 8 years of age, weighting 50.71 lb, was diagnosed with glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: aplastic anaemia, bone marrow failure, caecitis, pancytopenia, pneumonia , pseudomonas infection, pyelonephritis, respiratory failure. Temodal dosage: unknown. During the same period patient was treated with THALIDOMIDE, SEPTRIN. Patient died on 03/23/2007.


Temodal Side Effects Report #5199527-7
Temodal side effect was reported by a Consumer or non-health professional from JAPAN on Dec 25, 2006. Male patient, 83 years of age, was diagnosed with glioblastoma multiforme, neoplasm recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: anorexia, decreased activity, fungus serology test positive, interstitial lung disease, oral intake reduced, respiratory failure. Temodal dosage: 150 MG/M2; QD; PO. Patient died on 11/15/2006.

Temodal Side Effects Report #5477391-6
Temodal side effect was reported by a Physician from JAPAN on Sept 26, 2007. Male patient, 83 years of age, weighting 90.39 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: anorexia, decreased activity, fungal infection , opportunistic infection, oral intake reduced, pneumonia , respiratory failure. Temodal dosage: 150 MG/M2;QD;PO. During the same period patient was treated with PREDONINE, FAMOTIDINE, MUCOSTA, AMINO ACIDS, PENTCILLIN. Patient died on 11/15/2006.

Temodal Side Effects Report #6085257-6
Temodal side effect was reported by a Physician from JAPAN on Feb 10, 2009. Male patient, 72 years of age, weighting 110.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: cardiac failure, hyperkalaemia, interstitial lung disease, multi-organ failure, renal failure, respiratory failure, viral infection . Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with SIGMART, SELOKEN, NORVASC, CARDENALIN, MEVALOTIN, FRANDOL S, EXCEGRAN. Patient died on 01/22/2009.

Temodal Side Effects Report #4575931-2
Temodal side effect was reported by a Physician from on Jan 27, 2005. Male patient, 72 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: platelet count decreased, respiratory failure. Temodal dosage: 200MG/M2 QD ORAL. Patient died on 12/07/2004.

Temodal Side Effects Report #4592677-5
Temodal side effect was reported by a Physician from on Feb 10, 2005. Male patient, 72 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, neoplasm progression, respiratory failure, somnolence, thrombocytopenia. Temodal dosage: 400 MG QD ORAL; SEE IMAGE. During the same period patient was treated with GLIOBLASTOMAME, HAPARINECTABLE, METAMIZOLE. Patient was hospitalized. Patient died on 12/07/2004.


Temodal Side Effects Report #5535115-8
Temodal side effect was reported by a Physician from JAPAN on Nov 28, 2007. Male patient, 71 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, dysphagia, injury, intracranial tumour haemorrhage, pneumonia aspiration, pneumonia pneumococcal, respiratory failure, shock haemorrhagic. Temodal dosage: 150 MG/MD;QD;PO. During the same period patient was treated with BAKTAR, KYTRIL, GLYSENNID, ENTERONON, LOPEMIN, BUFFERIN. Patient was hospitalized and became disabled. Patient died on 04/24/2007.

Temodal Side Effects Report #5926310-4
Temodal side effect was reported by a Physician from JAPAN on Oct 15, 2008. Male patient, 71 years of age, weighting 105.8 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, dysphagia, intracranial tumour haemorrhage, pneumonia aspiration, pneumonia pneumococcal, respiratory failure, shock haemorrhagic, subarachnoid haemorrhage. Temodal dosage: 150 MG/M2;QD;PO, 150 MG/M2;QD;PO. During the same period patient was treated with COTRIM, KYTRIL, PURSENNID, ENTERONON, LOPEMIN, BUFFERIN. Patient was hospitalized and became disabled. Patient died on 04/24/2007.

Temodal Side Effects Report #5328642-X
Temodal side effect was reported by a Physician from JAPAN on May 07, 2007. Female patient, 70 years of age, weighting 92.59 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, cytomegalovirus infection , disseminated intravascular coagulation, hepatic function abnormal, interstitial lung disease, platelet count decreased, respiratory failure, sepsis . Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with FERON, BENAMBAX, PREDNISOLONE, NEO MINOPHAGEN C, LEBENIN, TANNALBIN, EXCEGRAN, VANCOMYCIN HYDROCHLORIDE. Patient died on 03/28/2007.

Temodal Side Effects Report #5928846-9
Temodal side effect was reported by a Physician from JAPAN on Oct 15, 2008. Female patient, 70 years of age, weighting 92.59 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, cytomegalovirus infection , disseminated intravascular coagulation, hepatic function abnormal, interstitial lung disease, respiratory failure, sepsis . Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with FERON, BENAMBAX, PREDNISOLONE, NEO MINOPHAGEN C, LEBENIN, TANNALBIN, EXCEGRAN, VANCOMYCIN HYDROCHLORIDE. Patient died on 03/28/2007.

Temodal Side Effects Report #5689813-6
Temodal side effect was reported by a Physician from JAPAN on Mar 24, 2008. Female patient, 67 years of age, weighting 101.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: altered state of consciousness, convulsion, disease progression, hydrocephalus , hypoproteinaemia, lymphocyte count decreased, pneumocystis jiroveci pneumonia, respiratory failure. Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with ZOFRAN, NIVADIL, SIMVASTATIN, CARDENALIN, GASTER D, ZONISAMIDE, WAKOBITAL, PREDNISOLONE. Patient was hospitalized. Patient died on 12/03/2007.


Temodal Side Effects Report #5232451-X
Temodal side effect was reported by a Physician from JAPAN on Feb 01, 2007. Male patient, 64 years of age, weighting 112.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: bacterial infection , pneumocystis jiroveci pneumonia, respiratory failure. Temodal dosage: 150 MG/M2; QD; PO; SEE IMAGE. During the same period patient was treated with RINDERON, EXCEGRAN. Patient died on 01/12/2007.

Temodal Side Effects Report #5258673-X
Temodal side effect was reported by a Physician from JAPAN on Feb 27, 2007. Male patient, 64 years of age, weighting 112.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: bronchitis bacterial, lymphocyte count decreased, pneumocystis jiroveci pneumonia, respiratory failure. Temodal dosage: 150 MG/M2;QD;PO; 200 MG/M2;QD;PO. During the same period patient was treated with RINDERON, EXCEGRAN. Patient died on 01/12/2007.

Temodal Side Effects Report #5468008-5
Temodal side effect was reported by a Physician from JAPAN on Sept 20, 2007. Male patient, 64 years of age, weighting 112.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: bronchitis bacterial, lymphocyte count decreased, pneumocystis jiroveci pneumonia, respiratory failure. Temodal dosage: 150 MG/M2; QD; PO; 200 MG/M2; QD;PO. During the same period patient was treated with RINDERON, EXCEGRAN. Patient died on 01/12/2007.

Temodal Side Effects Report #5808036-0
Temodal side effect was reported by a Physician from JAPAN on June 30, 2008. Male patient, 64 years of age, weighting 112.4 lb, was diagnosed with glioblastoma multiforme, disease recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: bronchitis bacterial, decubitus ulcer, depressed level of consciousness, lymphocyte count decreased, pneumocystis jiroveci pneumonia, pneumonia cytomegaloviral, respiratory failure, sputum retention. Temodal dosage: 150 MG/M2; QD; PO; 200 MG/M2; QD; PO. During the same period patient was treated with BETAMETHASONE, EXCEGRAN, PHENOBARBITAL. Patient died on 01/12/2007.

Temodal Side Effects Report #6016908-X
Temodal side effect was reported by a Physician from JAPAN on Dec 17, 2008. Male patient, 64 years of age, weighting 112.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: bacterial infection , bronchitis bacterial, decubitus ulcer, lymphocyte count decreased, pneumocystis jiroveci pneumonia, pneumonia cytomegaloviral, respiratory failure, sputum retention. Temodal dosage: 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with BETAMETHASONE, EXCEGRAN, PHENOBARBITAL. Patient died on 01/12/2007.


Temodal Side Effects Report #5317860-2
Temodal side effect was reported by a Physician from JAPAN on Apr 26, 2007. Male patient, 63 years of age, weighting 119.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, lung disorder, meningioma malignant, platelet count decreased, pneumonia , respiratory failure, shock, white blood cell count decreased. Temodal dosage: unknown. During the same period patient was treated with FERON, CYMERIN, TEGRETOL, EXCEGRAN, PENTCILLIN, SULPERAZON. Patient died on 10/14/2006.

Temodal Side Effects Report #5429903-6
Temodal side effect was reported by a Physician from JAPAN on Aug 21, 2007. Male patient, 63 years of age, weighting 119.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, lung disorder, platelet count decreased, pneumonia , respiratory failure, shock, white blood cell count decreased. Temodal dosage: 250 MG; QD; PO, 250 MG; QD; PO, 150 MG/M2; QD; PO. During the same period patient was treated with FERON, CYMERIN, TEGRETOL, EXCEGRAN, PENTCILLIN, SULPERAZON. Patient died on 10/14/2006.

Temodal Side Effects Report #4929507-5
Temodal side effect was reported by a Physician from SPAIN on Feb 15, 2006. Female patient, 54 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: bone marrow failure, pyrexia, respiratory failure, subdural haematoma. Temodal dosage: 75 MG/M2 QD ORAL. During the same period patient was treated with FORTECORTIN, DAONIL. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5306418-7
Temodal side effect was reported by a Physician from JAPAN on Apr 13, 2007. Female patient was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, cytomegalovirus infection , interstitial lung disease, lymphocyte count decreased, respiratory failure. Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with FERON, STEROID. Patient died on 03/28/2007.

Temodal Side Effects Report #5757742-5
Temodal side effect was reported by a Consumer or non-health professional from AUSTRIA on May 23, 2008. Female patient, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: alveolitis, apparent life threatening event, oedema mucosal, pneumocystis jiroveci infection, pneumonitis, respiratory failure. Temodal dosage: unknown. During the same period patient was treated with OMEPRAZOLE, FLUOXETINE, VALPROAT, LEVETIRACETAM. Patient was hospitalized. Patient recovered.


Temodal Side Effects Report #5766792-4
Temodal side effect was reported by a Consumer or non-health professional from AUSTRIA on June 04, 2008. Female patient, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: alveolitis, pneumocystis jiroveci infection, pneumonitis, respiratory failure. Temodal dosage: unknown. During the same period patient was treated with OMEPRAZOLE, FLUOXETINE, VALPROAT, LEVETIRACETAM. Patient was hospitalized. Patient died on 06/03/2008.

Temodal Side Effects Report #5786686-8
Temodal side effect was reported by a Consumer or non-health professional from AUSTRIA on June 16, 2008. Female patient, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: alveolitis, bronchial disorder, oedema mucosal, pneumocystis jiroveci infection, pneumonitis, respiratory failure. Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with OMEPRAZOL, FLUOXETIN, VALPROAT, LEVETIRACETAM, SELOKEN, CONVULEX, KEPPRA, FORTECORTIN. Patient was hospitalized. Patient died on 06/03/2008.

Temodal Side Effects Report #5839517-1
Temodal side effect was reported by a Health Professional from AUSTRIA on July 31, 2008. Female patient, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: alveolitis, bronchial oedema, pneumocystis jiroveci infection, pneumonitis, pulmonary oedema, respiratory failure. Temodal dosage: 75 MG/M2;QD;PO. During the same period patient was treated with OMEPRAZOLE, FLUOXETINE, VALPROAT, LEVETIRACETAM, SELOKEN, CONVULEX, KEPPRA, FORTECORTIN. Patient was hospitalized. Patient died on 06/03/2008.

Temodal Side Effects Report #5215556-9
Temodal side effect was reported by a Physician from JAPAN on Jan 09, 2007. Female patient, 65 years of age, weighting 114.6 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, depressed level of consciousness, leukopenia, no therapeutic response, pneumocystis jiroveci pneumonia, respiratory failure. Temodal dosage: unknown. During the same period patient was treated with DEPAKENE, DOGMATYL, ZYLORIC, TRANSAMIN, BLOPRESS, COMELIAN. Patient was hospitalized. Patient died on 11/08/2006.

Temodal Side Effects Report #5225202-6
Temodal side effect was reported by a Physician from JAPAN on Jan 24, 2007. Female patient, 65 years of age, weighting 114.6 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, blood beta-d-glucan increased, depressed level of consciousness, no therapeutic response, platelet count decreased, pneumocystis jiroveci pneumonia, respiratory failure, white blood cell count decreased. Temodal dosage: unknown. During the same period patient was treated with DEPAKENE, DOGMATYL, ZYLORIC, TRANSAMIN, BLOPRESS, COMELIAN. Patient was hospitalized. Patient died on 11/08/2006.


Temodal Side Effects Report #5378518-7
Temodal side effect was reported by a Physician from JAPAN on June 29, 2007. Female patient, 65 years of age, weighting 114.6 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, depressed level of consciousness, leukopenia, platelet count decreased, pneumocystis jiroveci pneumonia, respiratory failure. Temodal dosage: unknown. During the same period patient was treated with DEPAKENE, DOGMATYL, ALLOPURINOL, TRANSAMIN, BLOPRESS, COMELIAN. Patient was hospitalized. Patient died on 11/08/2006.

Temodal Side Effects Report #5888702-1
Temodal side effect was reported by a Physician from FRANCE on Sept 12, 2008. Male patient, 74 years of age, weighting 152.1 lb, was diagnosed with central nervous system lymphoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: cardiac disorder, hyperthermia, lung disorder, pulmonary congestion, respiratory distress, respiratory failure. Temodal dosage: 270 MG; QD; PO; PO. During the same period patient was treated with METHOTREXATE. Patient was hospitalized. Patient died on 03/24/2008.

Temodal Side Effects Report #5982117-3
Temodal side effect was reported by a Consumer or non-health professional from JAPAN on Nov 27, 2008. Male patient, 59 years of age, weighting 110.2 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: interstitial lung disease, respiratory failure. Temodal dosage: 75 MG;QD;PO 150 MG;QD;PO. During the same period patient was treated with NASEA, ALEVIATIN, MAGNESIUM OXIDE. Patient was hospitalized. Patient recovered.