Temodal and neoplasm progression Patient Reports February 12, 2012

Temodal Side Effects Report #5919053-4
Temodal side effect was reported by a Physician from JAPAN on Oct 06, 2008. Male patient, 63 years of age, weighting 156.5 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: convulsion, myelodysplastic syndrome, neoplasm progression, pneumonia , respiratory failure. Temodal dosage: unknown. During the same period patient was treated with DEPAKENE, TEGRETOL. Patient was hospitalized. Patient died on 11/27/2007.

Temodal Side Effects Report #5494424-1
Temodal side effect was reported by a Physician from JAPAN on Oct 18, 2007. Male patient, 48 years of age, weighting 105.8 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood chloride decreased, blood glucose increased, blood sodium decreased, disseminated intravascular coagulation, neoplasm progression, pneumonia , white blood cell count decreased. Temodal dosage: PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with BAKTAR, ZOFRAN, PRIMPERAN, LENDORMIN D, EXCEGRAN. Patient died on 03/06/2007.

Temodal Side Effects Report #5843888-X
Temodal side effect was reported by a Physician from JAPAN on Aug 04, 2008. Male patient, 46 years of age, weighting 123.5 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, disseminated intravascular coagulation, neoplasm progression, postoperative wound infection, pulmonary alveolar haemorrhage, shock. Temodal dosage: unknown. During the same period patient was treated with CARBOPLATIN, RIVOTRIL, EXCEGRIN. Patient was hospitalized. Patient died on 06/04/2007.

Temodal Side Effects Report #4672360-8
Temodal side effect was reported by a Physician from on May 11, 2005. Female patient, 24 years of age, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: cerebral haemorrhage, contusion, convulsion, hypoaesthesia, malignant neoplasm progression, oligodendroglioma, paraesthesia. Temodal dosage: 200 MGQDX5D ORAL. Patient was hospitalized. Patient recovered.


Temodal Side Effects Report #5339418-1
Temodal side effect was reported by a Pharmacist from JAPAN on May 18, 2007. Female patient, 59 years of age, weighting 105.8 lb, was diagnosed with mixed oligo-astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: aspiration, brain neoplasm, disseminated intravascular coagulation, electrolyte imbalance, neoplasm progression, pancytopenia, pneumonia , renal failure acute. Temodal dosage: unknown. During the same period patient was treated with BAKTAR, BENAMBAX, RADEN, RITALIN, CHOLINE, PREDNISOLONE. Patient was hospitalized and became disabled. Patient recovered.

Temodal Side Effects Report #4978892-7
Temodal side effect was reported by a Physician from CANADA on Apr 06, 2006. Male patient, 58 years of age, was diagnosed with mixed oligo-astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: glioma, myopathy, neoplasm progression. Temodal dosage: 400 MG QD ORAL. During the same period patient was treated with DECADRON, CLOBAZAM, TEGRETOL. Patient died on 04/03/2006.

Temodal Side Effects Report #4749901-5
Temodal side effect was reported by a Physician from FRANCE on Aug 11, 2005. Male patient, 39 years of age, was diagnosed with mixed oligo-astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, diabetes mellitus, infection , neoplasm progression, pancytopenia, pyelonephritis, pyrexia, vomiting. Temodal dosage: unknown. Patient was hospitalized. Patient died on 09/08/2003.

Temodal Side Effects Report #5741407-X
Temodal side effect was reported by a Consumer or non-health professional from CANADA on May 09, 2008. Male patient, 38 years of age, was diagnosed with metastatic malignant melanoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: metastases to rectum, metastatic malignant melanoma, nasopharyngitis, neoplasm progression, neutropenia, pneumonia . Temodal dosage: 170 MG; QD; 125 MG; QD. During the same period patient was treated with DEXAMETHASONE, DILANTIN. Patient was hospitalized. Patient died on 05/06/2008.

Temodal Side Effects Report #5133890-8
Temodal side effect was reported by a Physician from SWITZERLAND on Oct 06, 2006. Female patient, 76 years of age, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: diverticular perforation, diverticulitis, neoplasm progression, pneumoperitoneum, thrombocytopenia. Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with PANTOPRAZOL, DEXAMETHASONE, FLUCONAZOLE, BACTRIMTE, CEFTRIAXONE, METRONIDAZOLE. Patient was hospitalized. Patient died on 12/03/2005.


Temodal Side Effects Report #5134276-2
Temodal side effect was reported by a Physician from SWITZERLAND on Oct 06, 2006. Female patient, 76 years of age, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: diverticulitis, intestinal perforation, neoplasm progression, thrombocytopenia. Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with PANTOPRAZOL, DEXAMETHASONE, FLUCONAZOLE, BACTRIMTE, CEFTRIAXONE, METRONIDAZOLE. Patient was hospitalized. Patient died on 12/03/2005.

Temodal Side Effects Report #5139654-3
Temodal side effect was reported by a Physician from SWITZERLAND on Oct 06, 2006. Female patient, 76 years of age, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: abdominal pain , constipation , diverticulitis, neoplasm progression, pneumoperitoneum, thrombocytopenia. Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with PANTOPRAZOLE, DEXAMETHASONE, FLUCONAZOLE, BACTRIM DS, CEFTRIAXONE, METRONIDAZOLE. Patient was hospitalized. Patient died on 12/03/2005.

Temodal Side Effects Report #4854314-1
Temodal side effect was reported by a Physician from SWITZERLAND on Dec 06, 2005. Female patient, 76 years of age, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: diverticulitis, neoplasm progression, pneumoperitoneum, thrombocytopenia. Temodal dosage: 120MG OD PO ORAL. During the same period patient was treated with PANTOPRAZOL, DEXAMETHASONE, FLUCONAZOLE, BACTRIM DS, CEFTRIAXONE, METRONIDAZOLE. Patient was hospitalized. Patient died on 12/03/2005.

Temodal Side Effects Report #4712393-6
Temodal side effect was reported by a Physician from GERMANY on June 30, 2005. Female patient, 60 years of age, weighting 145.5 lb, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: female genital-digestive tract fistula, haemoglobin decreased, haemorrhage, neoplasm progression, thrombocytopenia. Temodal dosage: 90 MG QD. Patient died on 04/11/2005.

Temodal Side Effects Report #4788288-9
Temodal side effect was reported by a Physician from GERMANY on Sept 22, 2005. Female patient, 60 years of age, weighting 145.5 lb, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: female genital tract fistula, gastrointestinal haemorrhage, haemoglobin decreased, neoplasm progression, thrombocytopenia. Temodal dosage: 90 MG QD. Patient died on 04/11/2005.


Temodal Side Effects Report #4791839-1
Temodal side effect was reported by a Physician from GERMANY on Sept 22, 2005. Female patient, 60 years of age, weighting 145.5 lb, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: female genital tract fistula, genital haemorrhage, haemoglobin decreased, neoplasm progression, thrombocytopenia. Temodal dosage: 90 MG QD. Patient died on 04/11/2005.

Temodal Side Effects Report #5527909-X
Temodal side effect was reported by a Physician from JAPAN on Nov 20, 2007. Male patient, 24 years of age, weighting 94.80 lb, was diagnosed with medulloblastoma recurrent and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, neoplasm progression, pneumonia , respiratory disorder, staphylococcal infection . Temodal dosage: PO; 200 MG/M2;QD; PO. During the same period patient was treated with RANIMUSTINE, METHOTREXATE, IFOSFAMIDE, LOXONIN, PREDNISOLONE. Patient was hospitalized. Patient died on 02/21/2007.

Temodal Side Effects Report #5477438-7
Temodal side effect was reported by a Pharmacist from JAPAN on Sept 25, 2007. Female patient, 59 years of age, weighting 105.8 lb, was diagnosed with lymphoma  and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, electrolyte imbalance, enterococcal infection, neoplasm progression, pancytopenia, pneumonia bacterial, renal failure acute, staphylococcal infection . Temodal dosage: 75 MG/M2;QD;PO; 150 MG/M2;QD;PO. During the same period patient was treated with BAKTAR, BENAMBAX, RADEN, RITALIN, CHOLINE, PREDNISOLONE, GLYCYRON. Patient was hospitalized. Patient died on 06/27/2007.

Temodal Side Effects Report #5162009-2
Temodal side effect was reported by a Physician from GERMANY on Nov 14, 2006. Male patient, 69 years of age, weighting 187.4 lb, was diagnosed with glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: angiopathy, cardiac failure, disturbance in attention, epilepsy , neoplasm progression. Temodal dosage: 205 MG;QD;PO. Patient was hospitalized. Patient died on 03/27/2006.

Temodal Side Effects Report #4989782-8
Temodal side effect was reported by a Physician from GERMANY on Apr 20, 2006. Female patient, 50 years of age, weighting 154.3 lb, was diagnosed with glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: neoplasm progression. Temodal dosage: 270 MG QDX5D ORAL. Patient was hospitalized. Patient died on 10/01/2005.


Temodal Side Effects Report #5003637-4
Temodal side effect was reported by a Physician from GERMANY on May 03, 2006. Female patient, 50 years of age, weighting 154.3 lb, was diagnosed with glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: neoplasm progression. Temodal dosage: 270 MG QDX5D ORAL. Patient was hospitalized. Patient died on 10/26/2005.

Temodal Side Effects Report #5748749-2
Temodal side effect was reported by a Physician from JAPAN on May 16, 2008. Female patient, 36 years of age, weighting 101.4 lb, was diagnosed with glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, dysphagia, eating disorder , malnutrition, neoplasm progression, paralysis , pneumonia aspiration. Temodal dosage: 150 MG/M2; QD; PO. During the same period patient was treated with MUCOSTA, MAGNESIUM OXIDE, DEPAKENE, SP TROCHE, GLYSENNID. Patient died on 02/08/2007.

Temodal Side Effects Report #5739564-4
Temodal side effect was reported by a Physician from JAPAN on May 08, 2008. Female patient, 79 years of age, weighting 105.8 lb, was diagnosed with glioblastoma multiforme, convulsion and was treated with Temodal. After drug was administered, patient experienced the following side effects: hepatic function abnormal, metastases to central nervous system, neoplasm progression, neutrophil count decreased, white blood cell count decreased. Temodal dosage: unknown. During the same period patient was treated with DEPAKENE, SEROQUEL, NAVOBAN. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #4592677-5
Temodal side effect was reported by a Physician from on Feb 10, 2005. Male patient, 72 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, neoplasm progression, respiratory failure, somnolence, thrombocytopenia. Temodal dosage: 400 MG QD ORAL; SEE IMAGE. During the same period patient was treated with GLIOBLASTOMAME, HAPARINECTABLE, METAMIZOLE. Patient was hospitalized. Patient died on 12/07/2004.

Temodal Side Effects Report #5451955-8
Temodal side effect was reported by a Physician from JAPAN on Sept 05, 2007. Male patient, 71 years of age, weighting 101.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, hyponatraemia, lymphocyte count decreased, malignant neoplasm progression, pneumonia , pyrexia. Temodal dosage: 10 MG/M2;QD;PO; 200 MG/M2;QD;PO. During the same period patient was treated with PHENOBARBITAL, FLIVAS, DIGITOXIN, PERINDOPRIL ERBUMINE, DIOVAN, AMLODIPINE. Patient died on 01/15/2007.


Temodal Side Effects Report #5679742-6
Temodal side effect was reported by a Physician from JAPAN on Mar 19, 2008. Male patient, 71 years of age, weighting 101.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, brain neoplasm, disseminated intravascular coagulation, hyponatraemia, lymphocyte count decreased, neoplasm progression, pneumonia staphylococcal, sputum culture positive. Temodal dosage: 150 MG/M2; QD; PO; 200 MG/M2; QD; PO. During the same period patient was treated with PHENOBARBITAL, FLIVAS, DIGITOXIN, COVERSYL, DIOVAN, AMLODIN. Patient died on 01/15/2007.

Temodal Side Effects Report #5878587-1
Temodal side effect was reported by a Physician from JAPAN on Sept 03, 2008. Male patient, 70 years of age, weighting 127.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, depressed level of consciousness, hypophagia, neoplasm progression, oedema. Temodal dosage: 72 MG/M2; QD; PO, 150 MG/M2; QD; PO. During the same period patient was treated with COTRIM, PHENOBARBITAL, FAMOTIDINE, CHLORIDE, MAGNESIUM OXIDE. Patient recovered.

Temodal Side Effects Report #5776194-2
Temodal side effect was reported by a Physician from JAPAN on June 09, 2008. Female patient, 69 years of age, weighting 130.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: bone marrow failure, c-reactive protein increased, condition aggravated, depressed level of consciousness, gastric ulcer, hepatic function abnormal, melaena, neoplasm progression, pneumonia . Temodal dosage: 150 MG/M2;QD; PO. During the same period patient was treated with BAKTAR, DEPAKENE, BETAMETHASONE, TAGAMET, ZYPREXA. Patient died on 01/19/2007.

Temodal Side Effects Report #5971753-6
Temodal side effect was reported by a Consumer or non-health professional from PORTUGAL on Nov 17, 2008. Female patient, 69 years of age, weighting 130.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: aplastic anaemia, clostridial infection, neoplasm progression, sepsis . Temodal dosage: 75 MG/M2;QD;PO. During the same period patient was treated with OMEPRAZOLE, CORTICOSTEROIUS, VALPROIC ACID, DEXAMETHASONE, VALPROATE, LEVOTHYROXINE . Patient was hospitalized. Patient died on 10/11/2008.

Temodal Side Effects Report #5353141-9
Temodal side effect was reported by a Physician from JAPAN on June 01, 2007. Male patient, 68 years of age, weighting 127.9 lb, was diagnosed with glioblastoma multiforme, antifungal prophylaxis and was treated with Temodal. After drug was administered, patient experienced the following side effects: convulsion, disease progression, hepatic function abnormal, neoplasm progression, performance status decreased, pyrexia, rash , vomiting. Temodal dosage: 75 MG/M2;QD;PO. During the same period patient was treated with BACTRIM, VALPROATE, FAMOTIDINE, GLYCEOL, DECADRON, PREDNISOLONE, WAKOBITAL, MAGMITT. Patient died on 05/15/2007.


Temodal Side Effects Report #5345434-6
Temodal side effect was reported by a Physician from JAPAN on May 24, 2007. Female patient, 67 years of age, weighting 101.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: c-reactive protein increased, convulsion, hydrocephalus , hypoproteinaemia, lymphocyte count decreased, neoplasm progression, pneumocystis jiroveci pneumonia. Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with ZOFRAN, NIVADIL, LIPOVAS, CARDENALIN, GASTER D, EXCEGRAN, WAKOBITAL. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5508658-0
Temodal side effect was reported by a Physician from JAPAN on Oct 30, 2007. Female patient, 67 years of age, weighting 101.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: altered state of consciousness, c-reactive protein increased, convulsion, hydrocephalus , hypoproteinaemia, lymphocyte count decreased, neoplasm progression, pneumocystis jiroveci pneumonia, respiratory failure. Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with ZOFRAN, NIVADIL, SIMVASTATIN, DOXAZOSIN MESYLATE, FAMOTIDINE, EXCEGRAN, WAKOBITAL, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5458130-1
Temodal side effect was reported by a Physician from JAPAN on Sept 11, 2007. Male patient, 66 years of age, weighting 114.6 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: altered state of consciousness, glioblastoma multiforme, neoplasm progression, oral intake reduced, platelet count decreased, pneumonia aspiration. Temodal dosage: ; PO : 200 MG/M2; QD; PO : 200 MG/M2; QD; PO : 200 MG/M2; QD; PO : 200 MG/M2; QD; PO. During the same period patient was treated with BAKTAR, FAMOTIDINE, HYDANTOL, SERMION. Patient recovered.

Temodal Side Effects Report #5885696-X
Temodal side effect was reported by a Physician from JAPAN on Sept 09, 2008. Male patient, 66 years of age, weighting 110.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: hypophagia, neoplasm progression, pneumonia haemophilus, pneumonia primary atypical. Temodal dosage: 150 MG/M2; QD; PO, 205 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with ZOFRAN ZYDIS. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5742367-8
Temodal side effect was reported by a Physician from JAPAN on May 08, 2008. Male patient, 59 years of age, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: dyspnoea, hemiplegia, mobility decreased, neoplasm progression, neoplasm recurrence, neutrophil count decreased, platelet count decreased, venous thrombosis, white blood cell count decreased. Temodal dosage: 75 MG/M2; QD; PO; 150 MG/M2; QD; PO; 200 MG/M2; QD; PO. Patient was hospitalized and became disabled. Patient recovered.


Temodal Side Effects Report #5917630-8
Temodal side effect was reported by a Physician from JAPAN on Oct 06, 2008. Male patient, 59 years of age, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: cough, dyspnoea, hemiplegia, mobility decreased, neoplasm progression, neoplasm recurrence, neutrophil count decreased, platelet count decreased, venous thrombosis. Temodal dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. Patient was hospitalized and became disabled. Patient died on 01/28/2008.

Temodal Side Effects Report #6121918-8
Temodal side effect was reported by a Physician from JAPAN on Mar 06, 2009. Male patient, 59 years of age, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: aphasia , dyspnoea, hemiplegia, neoplasm progression, neoplasm recurrence, neutrophil count decreased, platelet count decreased, venous thrombosis, white blood cell count decreased. Temodal dosage: unknown. Patient was hospitalized and became disabled. Patient died on 01/28/2008.

Temodal Side Effects Report #5317875-4
Temodal side effect was reported by a Physician from JAPAN on Apr 27, 2007. Male patient, 54 years of age, weighting 163.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: neoplasm progression. Temodal dosage: 75 MG/M2; 150 MG/M2 : QD: PO. During the same period patient was treated with EXCEGRAN, RINDERON, GASTER, PURSENNID. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #6068392-8
Temodal side effect was reported by a Physician from JAPAN on Jan 29, 2009. Male patient, 46 years of age, weighting 121.3 lb, was diagnosed with glioblastoma multiforme, neoplasm recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: multi-organ failure, neoplasm progression, neoplasm recurrence, sepsis . Temodal dosage: 150 MG/M2;QD;PO; 200 MG/M2;QD;PO. Patient died on 02/28/2008.

Temodal Side Effects Report #5603301-4
Temodal side effect was reported by a Physician from GERMANY on Jan 09, 2008. Female patient, 43 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: fall , hemiparesis, ischaemic cerebral infarction, neoplasm progression, no therapeutic response. Temodal dosage: 340 MG;, 340 MG;. During the same period patient was treated with LEVETIRACETAM. Patient was hospitalized. Patient recovered.


Temodal Side Effects Report #5634213-8
Temodal side effect was reported by a Physician from GERMANY on Feb 14, 2008. Female patient, 43 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: fall , ischaemic cerebral infarction, neoplasm progression. Temodal dosage: 340 MG; 340 MG; QD; PO. During the same period patient was treated with LEVETIRACETAM. Patient was hospitalized. Patient died on 01/22/2008.

Temodal Side Effects Report #5533795-4
Temodal side effect was reported by a Physician from JAPAN on Nov 26, 2007. Male patient, 33 years of age, weighting 132.3 lb, was diagnosed with glioblastoma multiforme, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, gastric cancer, neoplasm progression, platelet count decreased. Temodal dosage: 220 MG/M2;QD;PO; 340 MG/M2;QD;PO. During the same period patient was treated with BAKTAR. Patient died on 08/17/2007.

Temodal Side Effects Report #6024299-3
Temodal side effect was reported by a Physician from JAPAN on Dec 16, 2008. Female patient, weighting 138.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: altered state of consciousness, disease progression, hemiparesis, hepatic function abnormal, neoplasm progression, speech disorder. Temodal dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD;PO, 200 MG/M;QD/PO. Patient died on 01/20/2008.

Temodal Side Effects Report #5937799-9
Temodal side effect was reported by a Physician from GERMANY on Oct 20, 2008. Male patient, 71 years of age, weighting 194.0 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain oedema, neoplasm progression, pyrexia. Temodal dosage: 200 MG;QD;PO. During the same period patient was treated with FORTECORTIN, AMLODIPINE, RAMIPRIL, HYDROCHLOROTHIAZIDE. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5758856-6
Temodal side effect was reported by a Physician from AUSTRIA on May 28, 2008. Female patient, 64 years of age, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: haemorrhage, neoplasm progression, somnolence, thrombocytopenia, tumour necrosis, white blood cell count decreased. Temodal dosage: unknown. During the same period patient was treated with OMEPRAZOLE, FORTECORTIN, KEPPRA, FRISIUM, NORVASC, MOXONIBENE, SEREVENT, FLIXOTIDE. Patient was hospitalized. Patient died on 05/09/2008.

Temodal Side Effects Report #5766838-3
Temodal side effect was reported by a Physician from AUSTRIA on June 05, 2008. Female patient, 64 years of age, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: haemorrhage, neoplasm progression, somnolence, thrombocytopenia, tumour necrosis, white blood cell count decreased. Temodal dosage: unknown. During the same period patient was treated with OMEPRAZOLE, FORTECORTIN, KEPPRA, FRISIUM, NORVASC, MOXONIBENE, SEREVENT, FLIXOTIDE. Patient was hospitalized. Patient died on 05/09/2008.

Temodal Side Effects Report #4609331-3
Temodal side effect was reported by a Physician from on Mar 04, 2005. Female patient, 64 years of age, weighting 138.9 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: aplasia, bone marrow myelogram abnormal, brain neoplasm, intracranial pressure increased, neoplasm progression, thrombocytopenia. Temodal dosage: unknown. During the same period patient was treated with BACTRIM, CALCITRIOL, DEROXAT, ESTROGEN NOS. Patient died on 09/09/2004.

Temodal Side Effects Report #5506307-9
Temodal side effect was reported by a Physician from UNITED KINGDOM on Oct 23, 2007. Male patient, 58 years of age, weighting 215.2 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: fall , ill-defined disorder, lower respiratory tract infection, lung consolidation, musculoskeletal pain, neoplasm progression, pleural effusion, pulmonary embolism . Temodal dosage: 170 MG; QD; PO. During the same period patient was treated with AUGMENTIN, DEXAMETHASONE, PHENYTOIN, CODEINE SUL, PARACETAMOL, METOCLOPRAMIDE, MORPHINE, OROMORPH. Patient was hospitalized and became disabled. Patient recovered.

Temodal Side Effects Report #5507376-2
Temodal side effect was reported by a Physician from UNITED KINGDOM on Oct 25, 2007. Male patient, 58 years of age, weighting 215.2 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: fall , lung consolidation, musculoskeletal pain, neoplasm progression, platelet count decreased, pleural effusion, pulmonary embolism . Temodal dosage: 170 MG;QD;PO. During the same period patient was treated with AUGMENTIN, DEXAMETHASONE, PHENYTOIN, CODEINE SUL, PARACETAMOL, METOCLOPRAMIDE, MORPHINE, OROMORPH. Patient was hospitalized and became disabled. Patient recovered.

Temodal Side Effects Report #5710666-1
Temodal side effect was reported by a Physician from SWEDEN on Apr 08, 2008. Male patient, 58 years of age, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: agranulocytosis, neoplasm progression, sepsis , thrombocytopenia. Temodal dosage: 360 MG; QD; PO. During the same period patient was treated with BETAPRED. Patient was hospitalized. Patient died.


Temodal Side Effects Report #5390030-8
Temodal side effect was reported by a Physician from GERMANY on July 06, 2007. Female patient was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: deep vein thrombosis , neoplasm progression, pulmonary embolism . Temodal dosage: 150 MC/M2; 200 MG/M2; 150 MG/M2. During the same period patient was treated with FORTECORTIN, NEXIUM. Patient died on 05/22/2006.

Temodal Side Effects Report #5483208-6
Temodal side effect was reported by a Physician from GERMANY on Oct 01, 2007. Female patient was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain oedema, disturbance in attention, lethargy, neoplasm progression, somnolence. Temodal dosage: unknown. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5500165-4
Temodal side effect was reported by a Physician from GERMANY on Oct 18, 2007. Female patient was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain oedema, neoplasm progression. Temodal dosage: unknown. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5905982-4
Temodal side effect was reported by a Physician from JAPAN on Sept 25, 2008. Female patient, 59 years of age, weighting 115.7 lb, was diagnosed with ependymoma malignant, neoplasm recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: activities of daily living impaired, hydrocephalus , nausea , neoplasm progression. Temodal dosage: 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with DEPAKENE, PRIMPERAN, NAVOBAN. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5567364-7
Temodal side effect was reported by a Physician from JAPAN on Dec 07, 2007. Male patient, 60 years of age, weighting 147.7 lb, was diagnosed with disease recurrence, glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, neoplasm progression, pneumonia aspiration, sepsis , vomiting, white blood cell count decreased. Temodal dosage: 15 MG/M2; QD; PO; 100 MG/M2; QD; PO; 150 MG/M2; QD; PO; 150 MG/M2; PO. During the same period patient was treated with EXCEGRAN. Patient recovered.

Temodal Side Effects Report #6094984-6
Temodal side effect was reported by a Physician from JAPAN on Feb 23, 2009. Male patient, 43 years of age, weighting 180.8 lb, was diagnosed with disease recurrence, glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, cerebral infarction, condition aggravated, disease progression, neoplasm progression, paralysis . Temodal dosage: 150 MG/M2;QD;PO; 150 MG/M2;QD;PO; 150 MG/M2;QD;PO; 150 MG/M2;QD;PO. During the same period patient was treated with KYTRIL. Patient died.

Temodal Side Effects Report #5483215-3
Temodal side effect was reported by a Physician from JAPAN on Oct 03, 2007. Male patient, child 6 years of age, weighting 35.27 lb, was diagnosed with brain neoplasm and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood urea increased, bone marrow failure, hypernatraemia, infection , lymphocyte count decreased, neoplasm progression, neutrophil count decreased, platelet count decreased, pneumonia bacterial. Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with VEPESID, BAKTAR, LASTET S, NASEA, PRIMPERAN, DECADRON, MANNITOL, BUPRENORPHINE. Patient died on 10/26/2006.

Temodal Side Effects Report #5318438-7
Temodal side effect was reported by a Physician from DENMARK on Apr 20, 2007. Male patient, 59 years of age, was diagnosed with brain neoplasm and was treated with Temodal. After drug was administered, patient experienced the following side effects: impaired work ability, neoplasm progression, polyneuropathy. Temodal dosage: 410 MG; QD; PO. During the same period patient was treated with PREDNISOLON, LAMICTAL, KEPPRA, LANSOPRAZOLE. Patient recovered.

Temodal Side Effects Report #5371234-7
Temodal side effect was reported by a Physician from DENMARK on June 14, 2007. Male patient, 59 years of age, was diagnosed with brain neoplasm and was treated with Temodal. After drug was administered, patient experienced the following side effects: gait disturbance, impaired work ability, neoplasm progression, pain in extremity, polyneuropathy. Temodal dosage: 410 MG; QD; PO. During the same period patient was treated with PREDNISOLON, LAMICTAL, KEPPRA, LANSOPRAZOLE. Patient recovered.

Temodal Side Effects Report #5928848-2
Temodal side effect was reported by a Consumer or non-health professional from BRAZIL on Oct 14, 2008. Male patient, 42 years of age, was diagnosed with brain neoplasm and was treated with Temodal. After drug was administered, patient experienced the following side effects: neoplasm progression, pneumonia bacterial. Temodal dosage: 100 MG; QD; PO. Patient died on 09/18/2008.


Temodal Side Effects Report #5085363-9
Temodal side effect was reported by a Physician from CANADA on Aug 09, 2006. Male patient, weighting 152.1 lb, was diagnosed with brain neoplasm and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain oedema, computerised tomogram abnormal, dysphasia, grand mal convulsion, neoplasm progression. Temodal dosage: 105 MG QD ORAL. During the same period patient was treated with WARFARIN, ATIVAN, DECADRON, KEPPRA. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5132748-8
Temodal side effect was reported by a Physician from CANADA on Oct 03, 2006. Male patient, weighting 152.1 lb, was diagnosed with brain neoplasm and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, dysphasia, dystrophic calcification, grand mal convulsion, neoplasm progression. Temodal dosage: 105 MG; QD; PO. During the same period patient was treated with WARFARIN, ATIVAN, DECADRON, KEPPRA. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5740229-3
Temodal side effect was reported by a Physician from JAPAN on May 08, 2008. Female patient, 52 years of age, weighting 94.80 lb, was diagnosed with astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: cerebellar ataxia, insomnia, neoplasm progression, neutrophil count abnormal, platelet count abnormal, restlessness, white blood cell count abnormal. Temodal dosage: PO; 200 MG/M2; QD; PO. During the same period patient was treated with DEPAKENE, PROCARBAZINE HYDROCHLORIDE, SELBEX. Patient was hospitalized. Patient died on 01/07/2008.

Temodal Side Effects Report #5757741-3
Temodal side effect was reported by a Physician from JAPAN on May 27, 2008. Female patient, 52 years of age, weighting 94.80 lb, was diagnosed with astrocytoma, neoplasm recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: cerebellar ataxia, insomnia, neoplasm progression, neoplasm recurrence, neutrophil count decreased, platelet count decreased, restlessness, white blood cell count decreased. Temodal dosage: PO; 200 MG/M2; QD; PO. Patient was hospitalized. Patient died on 01/07/2008.

Temodal Side Effects Report #4758189-0
Temodal side effect was reported by a Physician from GERMANY on Aug 19, 2005. Female patient, 24 years of age, weighting 154.3 lb, was diagnosed with astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain oedema, convulsion, depressed level of consciousness, extensor plantar response, gaze palsy, mydriasis, neoplasm progression, petechiae, sepsis . Temodal dosage: 340 MG QS ORAL. During the same period patient was treated with PANTOZOL. Patient was hospitalized. Patient died on 08/12/2005.

Temodal Side Effects Report #5698381-4
Temodal side effect was reported by a Physician from CANADA on Mar 28, 2008. Male patient, 17 years of age, weighting 124.1 lb, was diagnosed with astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain oedema, intracranial tumour haemorrhage, neoplasm progression, photophobia. Temodal dosage: 285 MG; QD; PO; 290 MG; QD; PO. During the same period patient was treated with ETOPOSIDE, CODEINE, DIMENHYDRINATE, COTRIMOXAZOLE, ONDANSETRON. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5704485-X
Temodal side effect was reported by a Physician from CANADA on Apr 04, 2008. Male patient, 17 years of age, weighting 124.1 lb, was diagnosed with astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain oedema, headache , neoplasm progression, photophobia, tumour haemorrhage, tumour necrosis, visual disturbance. Temodal dosage: 285 MG;QD;PO, 290 MG,QD;PO. During the same period patient was treated with ETOPOSIDE, CODEINE SUL, DIMENHYDRINATE, COTRIMOXAZOLE, ONDANSETRON. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5216950-2
Temodal side effect was reported by a Physician from GERMANY on Jan 15, 2007. Male patient, 78 years of age, weighting 180.8 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: deep vein thrombosis , neoplasm progression. Temodal dosage: 250 MG; QD. During the same period patient was treated with ONDANSETRON, FORTECORTIN, PLANTOZOL, TEGRETAL, IMBUN, AMPHO, DOMPERIDONE MALEATE. Patient died on 12/29/2006.

Temodal Side Effects Report #5812215-6
Temodal side effect was reported by a Physician from JAPAN on July 07, 2008. Male patient, 67 years of age, weighting 132.3 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: lymphocyte count decreased, neoplasm progression, pneumonia aspiration. Temodal dosage: 260 MG/M2; QD;PO, 200 MG/M2; QD; PO. During the same period patient was treated with FAMOTIDINE, PREDNISOLONE, VOLTRAEN, OXYCONTIN. Patient died on 02/10/2007.

Temodal Side Effects Report #5728552-X
Temodal side effect was reported by a Physician from JAPAN on Apr 24, 2008. Female patient, 56 years of age, weighting 141.1 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: activities of daily living impaired, hydrocephalus , nausea , neoplasm progression. Temodal dosage: 75 MG/M2; QD; PO ; 200 MG/M2; QD; PO ; 200 MG/M2; QD; PO. During the same period patient was treated with DEPAKENE, ZOFRAN ZYDIS, PRIMPERAN, NAVOBAN, NAUZELIN, PHENOBAL. Patient was hospitalized. Patient recovered.


Temodal Side Effects Report #5736891-1
Temodal side effect was reported by a Physician from JAPAN on May 07, 2008. Female patient, 56 years of age, weighting 115.7 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: activities of daily living impaired, hydrocephalus , nausea , neoplasm progression. Temodal dosage: 150 MG/M2; QD; PO; 200 MG/M2; QD; PO; 200 MG/M2; QD; PO. During the same period patient was treated with DEPAKENE, PRIMPERAN, NAVOBAN, NAUZELIN, PHENOBAL, MAGNESIUM OXIDE. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5940373-1
Temodal side effect was reported by a Physician from JAPAN on Oct 27, 2008. Male patient, 54 years of age, weighting 154.3 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain neoplasm, neoplasm progression, oedema peripheral, paralysis , pulmonary embolism . Temodal dosage: 150 MG/M2; QD; PO; 200 MG/M2; QD; PO. During the same period patient was treated with PHENOBARBITAL, ALEVIATIN, GASTER D, CELESTONE. Patient died on 04/10/2007.

Temodal Side Effects Report #5281137-4
Temodal side effect was reported by a Physician from JAPAN on Mar 13, 2007. Male patient, 53 years of age, weighting 125.7 lb, was diagnosed with anaplastic astrocytoma, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: deep vein thrombosis , dehydration, intracranial tumour haemorrhage, neoplasm progression, pneumonia . Temodal dosage: 150 MG/M2; QD; PO. During the same period patient was treated with SELBEX, LEXIN, SELENICA, PROTECADIN, MAGNESIUM OXIDE, RINDERON. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5506239-6
Temodal side effect was reported by a Physician from JAPAN on Oct 25, 2007. Male patient, 53 years of age, weighting 125.7 lb, was diagnosed with anaplastic astrocytoma, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood fibrinogen increased, deep vein thrombosis , dehydration, fibrin degradation products increased, intracranial tumour haemorrhage, neoplasm progression, pneumonia . Temodal dosage: 150 MG/M2; QD; PO. During the same period patient was treated with SELBEX, LEXIN, SELENICA, PROTECADIN, MAGNESIUM OXIDE, RINDERON. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5449481-5
Temodal side effect was reported by a Physician from JAPAN on Aug 31, 2007. Female patient, 38 years of age, weighting 110.2 lb, was diagnosed with anaplastic astrocytoma, disease recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: dehydration, headache , muscle spasms, nausea , neoplasm progression, neutrophil count decreased, platelet count decreased, pyrexia. Temodal dosage: ; PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5742497-0
Temodal side effect was reported by a Physician from JAPAN on May 08, 2008. Female patient, 38 years of age, weighting 110.2 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: convulsion, dehydration, headache , nausea , neoplasm progression, neutrophil count decreased, platelet count decreased, pyrexia. Temodal dosage: unknown. During the same period patient was treated with PHENOBARBITAL, BAKTAR, RINDERON. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5683550-X
Temodal side effect was reported by a Physician from JAPAN on Mar 21, 2008. Male patient, 22 years of age, weighting 149.9 lb, was diagnosed with anaplastic astrocytoma, convulsion and was treated with Temodal. After drug was administered, patient experienced the following side effects: altered state of consciousness, brain oedema, convulsion, disease progression, hemiplegia, hepatic function abnormal, neoplasm progression, platelet count decreased. Temodal dosage: unknown. During the same period patient was treated with DEPAKENE, TEGRETOL. Patient was hospitalized. Patient died on 06/24/2007.

Temodal Side Effects Report #5567453-7
Temodal side effect was reported by a Consumer or non-health professional from SPAIN on Dec 03, 2007. Male patient was treated with Temodal. After drug was administered, patient experienced the following side effects: dementia alzheimer's type, ejaculation failure, erectile dysfunction , neoplasm progression, vision blurred. Temodal dosage: 250 MG;. Patient recovered.