Temodal and disseminated intravascular coagulation Patient Reports February 12, 2012

Temodal Side Effects Report #5578567-X
Temodal side effect was reported by a Physician from JAPAN on Dec 21, 2007. Male patient, 69 years of age, weighting 108.0 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, disease progression, disseminated intravascular coagulation, malignant oligodendroglioma, melaena, multi-organ failure, shock, thrombocytopenia. Temodal dosage: 150 MG/M2; QD; PO. During the same period patient was treated with ONCOVIN, NATULAN, DEPAKENE, ZONISAMIDE. Patient died on 11/07/2006.

Temodal Side Effects Report #5766170-8
Temodal side effect was reported by a Physician from JAPAN on June 04, 2008. Male patient, 69 years of age, weighting 108.0 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, disseminated intravascular coagulation, loss of consciousness, melaena, multi-organ failure, oligodendroglioma, shock, thrombocytopenia. Temodal dosage: 150 MG/M2;QD;PO. During the same period patient was treated with ONCOVIN, NATULAN, DEPAKENE, EXCEGRAN. Patient died on 11/07/2006.

Temodal Side Effects Report #5494424-1
Temodal side effect was reported by a Physician from JAPAN on Oct 18, 2007. Male patient, 48 years of age, weighting 105.8 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood chloride decreased, blood glucose increased, blood sodium decreased, disseminated intravascular coagulation, neoplasm progression, pneumonia , white blood cell count decreased. Temodal dosage: PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with BAKTAR, ZOFRAN, PRIMPERAN, LENDORMIN D, EXCEGRAN. Patient died on 03/06/2007.

Temodal Side Effects Report #5818358-5
Temodal side effect was reported by a Physician from JAPAN on July 15, 2008. Male patient, 48 years of age, weighting 105.8 lb, was diagnosed with oligodendroglioma, disease recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood chloride decreased, blood glucose increased, blood sodium decreased, disease progression, disseminated intravascular coagulation, pneumonia , white blood cell count decreased. Temodal dosage: PO; 200 MG/M2; QD; PO. During the same period patient was treated with COTRIM, ZOFRAN, PRIMPERAN, LENDORMIN D, EXCEGRAN. Patient died on 03/06/2007.


Temodal Side Effects Report #6008366-6
Temodal side effect was reported by a Physician from JAPAN on Dec 08, 2008. Male patient, 48 years of age, weighting 105.8 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood chloride decreased, blood glucose increased, blood sodium decreased, condition aggravated, disease progression, disseminated intravascular coagulation, platelet count decreased, pneumonia , white blood cell count decreased. Temodal dosage: PO; 200 MG/M2;QD;PO; 200 MG/M2;QD;PO; 200 MG/M2;QD;PO. During the same period patient was treated with COTRIM, ZOFRAN, PRIMPERAN, LENDORMIN D, EXCEGRAN. Patient died on 03/06/2007.

Temodal Side Effects Report #5843888-X
Temodal side effect was reported by a Physician from JAPAN on Aug 04, 2008. Male patient, 46 years of age, weighting 123.5 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, disseminated intravascular coagulation, neoplasm progression, postoperative wound infection, pulmonary alveolar haemorrhage, shock. Temodal dosage: unknown. During the same period patient was treated with CARBOPLATIN, RIVOTRIL, EXCEGRIN. Patient was hospitalized. Patient died on 06/04/2007.

Temodal Side Effects Report #5408383-0
Temodal side effect was reported by a Physician from JAPAN on July 30, 2007. Male patient, 20 years of age, weighting 114.6 lb, was diagnosed with oligodendroglioma, disease recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, disease progression, disseminated intravascular coagulation, metastases to liver, metastases to lung, metastases to skin, platelet count decreased. Temodal dosage: PO, 150 MG/M2; QD; PO. During the same period patient was treated with BAKTAR, NASEA, BROCIN CODEINE, DECADRON, FAMOTIDINE, MAGMITT, PREDONINE. Patient died on 02/04/2007.

Temodal Side Effects Report #5588097-7
Temodal side effect was reported by a Physician from JAPAN on Dec 28, 2007. Male patient, 20 years of age, weighting 114.6 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, gastric perforation, hepatic function abnormal, meningeal disorder, metastases to liver, metastases to lung, metastases to skin. Temodal dosage: PO ; 150 MG/M2; QD PO. During the same period patient was treated with BAKTAR, NASEA, DECADRON, GASTER, MAGMITT, PREDONINE, METHOTREXATE. Patient died on 02/04/2007.

Temodal Side Effects Report #5226221-6
Temodal side effect was reported by a Physician from JAPAN on Jan 22, 2007. Male patient, 69 years of age, weighting 108.0 lb, was diagnosed with neoplasm recurrence, oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: disease progression, disseminated intravascular coagulation, melaena, multi-organ failure, shock, thrombocytopenia. Temodal dosage: 150 MG/M2; QD; PO. During the same period patient was treated with ACNU, ONCOVIN, NATULAN. Patient died on 11/07/2006.


Temodal Side Effects Report #5339418-1
Temodal side effect was reported by a Pharmacist from JAPAN on May 18, 2007. Female patient, 59 years of age, weighting 105.8 lb, was diagnosed with mixed oligo-astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: aspiration, brain neoplasm, disseminated intravascular coagulation, electrolyte imbalance, neoplasm progression, pancytopenia, pneumonia , renal failure acute. Temodal dosage: unknown. During the same period patient was treated with BAKTAR, BENAMBAX, RADEN, RITALIN, CHOLINE, PREDNISOLONE. Patient was hospitalized and became disabled. Patient recovered.

Temodal Side Effects Report #5959324-9
Temodal side effect was reported by a Physician from JAPAN on Nov 13, 2008. Male patient, 46 years of age, weighting 123.5 lb, was diagnosed with malignant oligodendroglioma, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory failure, bone marrow failure, disseminated intravascular coagulation, infection , malignant neoplasm progression, malignant oligodendroglioma, postoperative wound infection, pulmonary alveolar haemorrhage, shock. Temodal dosage: 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. Patient was hospitalized. Patient died on 06/04/2007.

Temodal Side Effects Report #5477438-7
Temodal side effect was reported by a Pharmacist from JAPAN on Sept 25, 2007. Female patient, 59 years of age, weighting 105.8 lb, was diagnosed with lymphoma  and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, electrolyte imbalance, enterococcal infection, neoplasm progression, pancytopenia, pneumonia bacterial, renal failure acute, staphylococcal infection . Temodal dosage: 75 MG/M2;QD;PO; 150 MG/M2;QD;PO. During the same period patient was treated with BAKTAR, BENAMBAX, RADEN, RITALIN, CHOLINE, PREDNISOLONE, GLYCYRON. Patient was hospitalized. Patient died on 06/27/2007.

Temodal Side Effects Report #5710504-7
Temodal side effect was reported by a Pharmacist from JAPAN on Apr 08, 2008. Female patient, 59 years of age, weighting 105.8 lb, was diagnosed with lymphoma  and was treated with Temodal. After drug was administered, patient experienced the following side effects: aspiration, disease progression, disseminated intravascular coagulation, electrolyte imbalance, enterococcal infection, ill-defined disorder, lymphoma , pancytopenia, pneumonia bacterial. Temodal dosage: 75 MG/M2,QD.PO; 150 MG/M2;QD;PO. During the same period patient was treated with BAKTAR, BENAMBAX, RADEN, RITALIN, CHOLINE, PREDNISOLONE. Patient was hospitalized. Patient died on 06/27/2007.

Temodal Side Effects Report #5458136-2
Temodal side effect was reported by a Physician from JAPAN on Sept 07, 2007. Male patient, 67 years of age, weighting 165.3 lb, was diagnosed with gliosarcoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: arterial stenosis limb, cardiac arrest , cellulitis , disseminated intravascular coagulation, epidermal necrosis, haemodialysis, palpitations, renal failure, septic shock. Temodal dosage: 75 MG/M2;QD;PO : 200 MG/M2;QD;PO. During the same period patient was treated with PREDNISOLONE, RHEUMATREX. Patient recovered.


Temodal Side Effects Report #5634212-6
Temodal side effect was reported by a Physician from JAPAN on Dec 14, 2007. Male patient, 67 years of age, weighting 165.3 lb, was diagnosed with gliosarcoma, rheumatoid arthritis  and was treated with Temodal. After drug was administered, patient experienced the following side effects: arrhythmia , cardiac arrest , cellulitis , decreased appetite, disseminated intravascular coagulation, epidermal necrosis, haemodialysis, hypoproteinaemia, oedema peripheral. Temodal dosage: 120 MG;QD; PO; 260 MG/M2;QD; PO; 340 MG/M2;QD;PO; 340 MG/M2;QD;PO; 360 MG/M2;QD;PO; 340 MG/M2;QD;PO. During the same period patient was treated with PREDNISOLONE, RHEUMATREX, DEPAKENE. Patient was hospitalized and became disabled. Patient recovered.

Temodal Side Effects Report #5755760-4
Temodal side effect was reported by a Physician from JAPAN on May 21, 2008. Male patient, 84 years of age, weighting 130.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: anaemia, anorexia, ascites, blood pressure decreased, diarrhoea, disseminated intravascular coagulation, electrolyte imbalance, gastrointestinal disorder. Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with OPALMON, TERNELIN, EXCEGRAN, FAMOTIDINE, PANTOSIN, MAGMITT. Patient recovered.

Temodal Side Effects Report #5762013-7
Temodal side effect was reported by a Physician from JAPAN on May 29, 2008. Male patient, 84 years of age, weighting 130.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: anaemia, anorexia, ascites, blood beta-d-glucan increased, blood pressure decreased, diarrhoea, disseminated intravascular coagulation, electrolyte imbalance, gastrointestinal disorder. Temodal dosage: 120 MG;QD;PO. During the same period patient was treated with OPALMON, TERNELIN, EXCEGRAN, FAMOTIDINE, PANTOSIN, MAGMITT. Patient died on 05/25/2008.

Temodal Side Effects Report #5825791-4
Temodal side effect was reported by a Consumer or non-health professional from JAPAN on July 18, 2008. Male patient, 84 years of age, weighting 130.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: anaemia, anorexia, ascites, blood beta-d-glucan increased, blood pressure decreased, diarrhoea, disseminated intravascular coagulation, electrolyte imbalance, gastrointestinal disorder. Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with OPALMON, TERNELIN, EXCEGRAN, GASTER D, PANTOSIN, MAGMITT. Patient died on 05/25/2008.

Temodal Side Effects Report #5309223-0
Temodal side effect was reported by a Physician from JAPAN on Apr 13, 2007. Male patient, 80 years of age, weighting 85.98 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, guttate psoriasis, platelet count decreased, pneumonia . Temodal dosage: unknown. During the same period patient was treated with PREDONINE, BASEN, STARSIS, PARULEON, MAGNESIUM OXIDE, DEPAS. Patient recovered.


Temodal Side Effects Report #5451914-5
Temodal side effect was reported by a Physician from JAPAN on Sept 06, 2007. Male patient, 80 years of age, weighting 85.98 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acarodermatitis, disseminated intravascular coagulation, guttate psoriasis, neutrophil count increased, platelet count decreased, pneumonia aspiration, renal impairment, urinary retention. Temodal dosage: unknown. During the same period patient was treated with PREDONINE, BASEN, STARSIS, PARULEON, MAGNESIUM OXIDE, DEPAS. Patient recovered.

Temodal Side Effects Report #5663867-5
Temodal side effect was reported by a Physician from JAPAN on Mar 05, 2008. Male patient, 80 years of age, weighting 85.98 lb, was diagnosed with glioblastoma multiforme, hypertension and was treated with Temodal. After drug was administered, patient experienced the following side effects: aspiration, disseminated intravascular coagulation, gastric ulcer, guttate psoriasis, hepatic function abnormal, neutrophil count increased, platelet count decreased, pneumonia , urinary retention. Temodal dosage: 150 MG/M2; QD; PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with BASEN, NATEGLINIDE, PREDNISONE, PARULEON, MAGNESIUM OXIDE, DEPAS. Patient recovered.

Temodal Side Effects Report #5951494-1
Temodal side effect was reported by a Physician from JAPAN on Nov 05, 2008. Male patient, 80 years of age, weighting 85.98 lb, was diagnosed with glioblastoma multiforme, hypertension and was treated with Temodal. After drug was administered, patient experienced the following side effects: acarodermatitis, aspiration, condition aggravated, disseminated intravascular coagulation, gastric ulcer, guttate psoriasis, hepatic function abnormal, neutrophil count increased, pneumonia . Temodal dosage: 150 MG/M2;QD;PO 200 MG/M2;QD;PO 200 MG/M2;QD;PO. During the same period patient was treated with BASEN, NATEGLINIDE, PREDONINE, PARULEON, MAGNESIUM OXIDE, DEPAS. Patient died on 04/20/2007.

Temodal Side Effects Report #5309224-2
Temodal side effect was reported by a Physician from JAPAN on Apr 18, 2007. Male patient, 71 years of age, weighting 101.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, glioblastoma multiforme, malignant neoplasm progression, pneumonia . Temodal dosage: unknown. During the same period patient was treated with GLYCEOL, PHENOBARBITAL, FLIVAS, DIGITOXIN, COVERSYL, DIOVAN, AMLODIN. Patient died on 01/15/2007.

Temodal Side Effects Report #5451955-8
Temodal side effect was reported by a Physician from JAPAN on Sept 05, 2007. Male patient, 71 years of age, weighting 101.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, hyponatraemia, lymphocyte count decreased, malignant neoplasm progression, pneumonia , pyrexia. Temodal dosage: 10 MG/M2;QD;PO; 200 MG/M2;QD;PO. During the same period patient was treated with PHENOBARBITAL, FLIVAS, DIGITOXIN, PERINDOPRIL ERBUMINE, DIOVAN, AMLODIPINE. Patient died on 01/15/2007.


Temodal Side Effects Report #5679742-6
Temodal side effect was reported by a Physician from JAPAN on Mar 19, 2008. Male patient, 71 years of age, weighting 101.4 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood alkaline phosphatase increased, brain neoplasm, disseminated intravascular coagulation, hyponatraemia, lymphocyte count decreased, neoplasm progression, pneumonia staphylococcal, sputum culture positive. Temodal dosage: 150 MG/M2; QD; PO; 200 MG/M2; QD; PO. During the same period patient was treated with PHENOBARBITAL, FLIVAS, DIGITOXIN, COVERSYL, DIOVAN, AMLODIN. Patient died on 01/15/2007.

Temodal Side Effects Report #5328642-X
Temodal side effect was reported by a Physician from JAPAN on May 07, 2007. Female patient, 70 years of age, weighting 92.59 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, cytomegalovirus infection , disseminated intravascular coagulation, hepatic function abnormal, interstitial lung disease, platelet count decreased, respiratory failure, sepsis . Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with FERON, BENAMBAX, PREDNISOLONE, NEO MINOPHAGEN C, LEBENIN, TANNALBIN, EXCEGRAN, VANCOMYCIN HYDROCHLORIDE. Patient died on 03/28/2007.

Temodal Side Effects Report #5754818-3
Temodal side effect was reported by a Physician from JAPAN on May 19, 2008. Female patient, 70 years of age, weighting 92.59 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, cytomegalovirus infection , disseminated intravascular coagulation, escherichia infection, hepatic function abnormal, interstitial lung disease, lymphocyte count decreased, platelet count decreased. Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with FERON, BENAMBAX, PREDNISOLONE, NEO MINOPHAGEN C, LEBENIN, TANNALBIN, EXCEGRAN, VANCOMYCIN HYDROCHLORIDE. Patient died on 03/28/2007.

Temodal Side Effects Report #5928846-9
Temodal side effect was reported by a Physician from JAPAN on Oct 15, 2008. Female patient, 70 years of age, weighting 92.59 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, anaemia, cytomegalovirus infection , disseminated intravascular coagulation, hepatic function abnormal, interstitial lung disease, respiratory failure, sepsis . Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with FERON, BENAMBAX, PREDNISOLONE, NEO MINOPHAGEN C, LEBENIN, TANNALBIN, EXCEGRAN, VANCOMYCIN HYDROCHLORIDE. Patient died on 03/28/2007.

Temodal Side Effects Report #5570153-0
Temodal side effect was reported by a Physician from JAPAN on Dec 13, 2007. Female patient, 65 years of age, weighting 121.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: altered state of consciousness, brain oedema, disseminated intravascular coagulation, pulmonary embolism , pulmonary infarction, white blood cell count decreased. Temodal dosage: 75 MG/M2; QD; PO; 150 MG/M2; QD; PO. During the same period patient was treated with DECADRON, BAKTAR, GLYCEOL, LOXONIN. Patient was hospitalized. Patient died on 01/30/2007.


Temodal Side Effects Report #5776553-8
Temodal side effect was reported by a Physician from JAPAN on June 09, 2008. Female patient, 65 years of age, weighting 121.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: altered state of consciousness, brain neoplasm, brain oedema, deep vein thrombosis , disseminated intravascular coagulation, headache , neutrophil count decreased, pulmonary embolism , pulmonary infarction. Temodal dosage: 75 MG/M2;QD;PO 150 MG/M2;QD;PO. During the same period patient was treated with DECADRON, BAKTAR, GLYCEOL, LOXONIN, FAMOTIDINE. Patient died on 01/30/2007.

Temodal Side Effects Report #6029387-3
Temodal side effect was reported by a Physician from JAPAN on Dec 25, 2008. Female patient, 65 years of age, weighting 121.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: altered state of consciousness, blood albumin decreased, blood creatinine increased, blood urea increased, blood uric acid increased, deep vein thrombosis , disseminated intravascular coagulation, lymphocyte count increased, monocyte count increased. Temodal dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO. During the same period patient was treated with DECADRON, COTRIM, GLYCEOL, LOXONIN, GASTER. Patient died on 01/30/2007.

Temodal Side Effects Report #5306619-8
Temodal side effect was reported by a Physician from JAPAN on Apr 10, 2007. Male patient, 60 years of age, weighting 147.7 lb, was diagnosed with glioblastoma multiforme, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, pneumonia aspiration, sepsis , vomiting. Temodal dosage: unknown. During the same period patient was treated with EXCERGRAN. Patient recovered.

Temodal Side Effects Report #5415381-X
Temodal side effect was reported by a Physician from JAPAN on Aug 08, 2007. Male patient, 60 years of age, weighting 147.7 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, platelet count decreased, pneumonia aspiration, sepsis , vomiting. Temodal dosage: 150 MG/M2; QD;PO; 100 MG/M2;QD;PO; 150 MG/M2;QD;PO; 150 MG/M2;QD;PO. During the same period patient was treated with EXCEGRAN, SELENICA, FAMOTIDINE, MYSTAN. Patient recovered.

Temodal Side Effects Report #5776555-1
Temodal side effect was reported by a Physician from JAPAN on June 11, 2008. Male patient, 60 years of age, weighting 147.7 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood pressure diastolic decreased, disease progression, disseminated intravascular coagulation, platelet count decreased, pneumonia aspiration, sepsis , vomiting, white blood cell count decreased. Temodal dosage: 150 MG/M2;QD;PO; 100 MG/M2;QD;PO. During the same period patient was treated with EXCEGRAN, SELENICA, FAMOTIDINE, MYSTAN. Patient died on 05/14/2008.


Temodal Side Effects Report #5313707-9
Temodal side effect was reported by a Physician from JAPAN on Apr 17, 2007. Male patient, 55 years of age, weighting 134.5 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, disseminated intravascular coagulation, herpes zoster disseminated, multi-organ failure, shock, staphylococcal sepsis. Temodal dosage: 120 MG;QD;PO. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5631962-2
Temodal side effect was reported by a Physician from JAPAN on Feb 07, 2008. Male patient, 55 years of age, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, disseminated intravascular coagulation, herpes virus infection, impetigo , multi-organ failure, shock, staphylococcal sepsis. Temodal dosage: 75 MG/M2;QD;PO; 100 MG/M2;QD;PO. During the same period patient was treated with BAKTAR, ALEVIATIN. Patient recovered.

Temodal Side Effects Report #5802840-0
Temodal side effect was reported by a Physician from JAPAN on June 30, 2008. Male patient, 55 years of age, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, basophil count increased, disseminated intravascular coagulation, hepatic function abnormal, herpes virus infection, hyperglycaemia, hypernatraemia, impetigo , lymphopenia. Temodal dosage: 75 MG/M2; QD; PO; 100 MG/M2; QD; PO. During the same period patient was treated with BAKTAR, ALEVIATIN. Patient recovered.

Temodal Side Effects Report #6016829-2
Temodal side effect was reported by a Physician from JAPAN on Dec 17, 2008. Male patient, 55 years of age, weighting 143.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory distress syndrome, basophil count increased, catheter site infection, disseminated intravascular coagulation, hepatic function abnormal, herpes virus infection, herpes zoster disseminated, hyperglycaemia, hypernatraemia. Temodal dosage: 75 MG/M2;QD/PO : 100 MG/M2;QD;PO. During the same period patient was treated with COTRIM, ALEVIATIN. Patient recovered.

Temodal Side Effects Report #5597648-8
Temodal side effect was reported by a Physician from JAPAN on Jan 11, 2008. Female patient, 70 years of age, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: cytomegalovirus infection , disseminated intravascular coagulation, pneumocystis jiroveci pneumonia, respiratory disorder. Temodal dosage: 100 MG; QD; PO. During the same period patient was treated with ZONISAMIDE, GLYBURIDE, AMLODIPINE BESYLATE, TAKEPRON OD, NITRAZEPAM. Patient died on 12/13/2007.


Temodal Side Effects Report #5273290-3
Temodal side effect was reported by a Physician from JAPAN on Mar 12, 2007. Male patient, 69 years of age, weighting 108.0 lb, was diagnosed with disease recurrence, oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, malignant neoplasm progression, melaena, multi-organ failure, shock, thrombocytopenia. Temodal dosage: 150 MG/M2; QD; PO. During the same period patient was treated with ONCOVIN, NATULAN, DEPAKENE, EXCEGRAN. Patient died on 11/07/2006.

Temodal Side Effects Report #5567364-7
Temodal side effect was reported by a Physician from JAPAN on Dec 07, 2007. Male patient, 60 years of age, weighting 147.7 lb, was diagnosed with disease recurrence, glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: disseminated intravascular coagulation, neoplasm progression, pneumonia aspiration, sepsis , vomiting, white blood cell count decreased. Temodal dosage: 15 MG/M2; QD; PO; 100 MG/M2; QD; PO; 150 MG/M2; QD; PO; 150 MG/M2; PO. During the same period patient was treated with EXCEGRAN. Patient recovered.

Temodal Side Effects Report #5297484-6
Temodal side effect was reported by a Physician from JAPAN on Mar 29, 2007. Male patient, 61 years of age, weighting 121.3 lb, was diagnosed with anaplastic astrocytoma, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood culture positive, cardio-respiratory arrest, disseminated intravascular coagulation, shock, staphylococcal infection . Temodal dosage: unknown. During the same period patient was treated with DEPAKENE R, DAONIL, GLIMICRON. Patient recovered.

Temodal Side Effects Report #5515809-0
Temodal side effect was reported by a Physician from JAPAN on Nov 06, 2007. Male patient, 61 years of age, weighting 121.3 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, disseminated intravascular coagulation, septic shock, staphylococcal infection . Temodal dosage: 150 MG/M2; QD; PO, 150 MG/M2; QD; PO, 150 MG/M2; QD; PO. During the same period patient was treated with DEPAKENE, GLYBURIDE, GLIMICRON, ABILIT. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5807669-5
Temodal side effect was reported by a Physician from JAPAN on July 03, 2008. Male patient, 61 years of age, weighting 121.3 lb, was diagnosed with anaplastic astrocytoma, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, disseminated intravascular coagulation, hepatic failure, shock, staphylococcal infection . Temodal dosage: 150 MG/M2; QD; PO, 150 MG/M2; QD; PO, 150 MG/M2; QD; PO. During the same period patient was treated with DEPAKENE, DAONIL, GLIMICRON. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5924210-7
Temodal side effect was reported by a Physician from JAPAN on Oct 10, 2008. Male patient, 61 years of age, weighting 121.3 lb, was diagnosed with anaplastic astrocytoma, neoplasm recurrence and was treated with Temodal. After drug was administered, patient experienced the following side effects: cardio-respiratory arrest, disseminated intravascular coagulation, hepatic function abnormal, liver disorder, septic shock, staphylococcal sepsis. Temodal dosage: unknown. During the same period patient was treated with DEPAKENE, DAONIL, GLIMICRON. Patient was hospitalized. Patient recovered.