Temodal and condition aggravated Patient Reports February 12, 2012

Temodal Side Effects Report #5578567-X
Temodal side effect was reported by a Physician from JAPAN on Dec 21, 2007. Male patient, 69 years of age, weighting 108.0 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, disease progression, disseminated intravascular coagulation, malignant oligodendroglioma, melaena, multi-organ failure, shock, thrombocytopenia. Temodal dosage: 150 MG/M2; QD; PO. During the same period patient was treated with ONCOVIN, NATULAN, DEPAKENE, ZONISAMIDE. Patient died on 11/07/2006.

Temodal Side Effects Report #5086022-9
Temodal side effect was reported by a Health Professional from FRANCE on Aug 15, 2006. Male patient, 62 years of age, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: acute respiratory failure, adrenal disorder, bone marrow failure, bronchopulmonary aspergillosis, condition aggravated, coordination abnormal, cyanosis, cytomegalovirus infection , depressed level of consciousness. Temodal dosage: 205 MG QD ORAL. During the same period patient was treated with CARMUSTINE, VALPROATE. Patient was hospitalized. Patient died on 04/04/2006.

Temodal Side Effects Report #4996145-8
Temodal side effect was reported by a Health Professional from FRANCE on Apr 24, 2006. Male patient, 62 years of age, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: aspergillosis, bone marrow failure, bronchopulmonary aspergillosis, condition aggravated, coordination abnormal, cytomegalovirus infection , embolism, febrile neutropenia. Temodal dosage: 205 MG QD ORAL. During the same period patient was treated with CARMUSTINE, VALPROATE, FORTUM, MEDROL, MANNITOL. Patient was hospitalized. Patient died on 04/04/2006.

Temodal Side Effects Report #6008366-6
Temodal side effect was reported by a Physician from JAPAN on Dec 08, 2008. Male patient, 48 years of age, weighting 105.8 lb, was diagnosed with oligodendroglioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood chloride decreased, blood glucose increased, blood sodium decreased, condition aggravated, disease progression, disseminated intravascular coagulation, platelet count decreased, pneumonia , white blood cell count decreased. Temodal dosage: PO; 200 MG/M2;QD;PO; 200 MG/M2;QD;PO; 200 MG/M2;QD;PO. During the same period patient was treated with COTRIM, ZOFRAN, PRIMPERAN, LENDORMIN D, EXCEGRAN. Patient died on 03/06/2007.


Temodal Side Effects Report #5237960-5
Temodal side effect was reported by a Physician from SWEDEN on Feb 01, 2007. Female patient was diagnosed with neoplasm malignant and was treated with Temodal. After drug was administered, patient experienced the following side effects: cognitive disorder, condition aggravated, deafness. Temodal dosage: unknown. Patient recovered.

Temodal Side Effects Report #4749901-5
Temodal side effect was reported by a Physician from FRANCE on Aug 11, 2005. Male patient, 39 years of age, was diagnosed with mixed oligo-astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, diabetes mellitus, infection , neoplasm progression, pancytopenia, pyelonephritis, pyrexia, vomiting. Temodal dosage: unknown. Patient was hospitalized. Patient died on 09/08/2003.

Temodal Side Effects Report #5069033-9
Temodal side effect was reported by a Physician from SWEDEN on July 19, 2006. Male patient, 59 years of age, was diagnosed with metastases to central nervous system and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, deafness, hearing impaired, tinnitus . Temodal dosage: unknown. During the same period patient was treated with BETAPRED. Patient recovered.

Temodal Side Effects Report #4767738-8
Temodal side effect was reported by a Physician from GERMANY on Sept 02, 2005. Female patient, 70 years of age, weighting 123.5 lb, was diagnosed with glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: agranulocytosis, bacteria sputum identified, candidiasis, cardiac failure, condition aggravated, electrolyte imbalance, enterococcal infection, fungal infection , interstitial lung disease. Temodal dosage: 75 MG/M^2 ORAL. During the same period patient was treated with TAVOR, PANTOZOL, REMERGIL, FORTECORTIN. Patient was hospitalized. Patient died on 06/20/2005.

Temodal Side Effects Report #5305362-9
Temodal side effect was reported by a Physician from JAPAN on Apr 12, 2007. Male patient, 45 years of age, weighting 143.3 lb, was diagnosed with glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: c-reactive protein increased, condition aggravated, gamma-glutamyltransferase increased, glioma, hepatic function abnormal, liver disorder, lymphocyte count decreased, malignant neoplasm progression, pneumonia aspiration. Temodal dosage: 240 MG; 340 MG : QD; PO. During the same period patient was treated with NIDRAN, METHOTREXATE, IFOSFAMIDE, CISPLATIN, ETOPOSIDE, BAKTAR, EXCEGRAN. Patient died on 01/05/2007.


Temodal Side Effects Report #5455181-8
Temodal side effect was reported by a Physician from FRANCE on Sept 04, 2007. Female patient, 39 years of age, weighting 167.6 lb, was diagnosed with glioma and was treated with Temodal. After drug was administered, patient experienced the following side effects: asthenia, balance disorder, condition aggravated, deafness neurosensory, hypoacusis. Temodal dosage: 320 MG;QD;PO. During the same period patient was treated with LEVOTHYROX, ASPEGIC, TEGRETOL, ALEPSAL, GARDAN, KEPPRA. Patient recovered.

Temodal Side Effects Report #5957357-X
Temodal side effect was reported by a Physician from JAPAN on Nov 12, 2008. Male patient, 83 years of age, weighting 90.39 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: anorexia, condition aggravated, decreased activity, eating disorder , fungal infection , haematotoxicity, immunodeficiency, interstitial lung disease, lymphocyte count decreased. Temodal dosage: 150 MG/M2;QD;PO. During the same period patient was treated with PREDONINE, GASTER D, MUCOSTA, AMINO ACIDS. Patient died on 11/15/2006.

Temodal Side Effects Report #5951494-1
Temodal side effect was reported by a Physician from JAPAN on Nov 05, 2008. Male patient, 80 years of age, weighting 85.98 lb, was diagnosed with glioblastoma multiforme, hypertension and was treated with Temodal. After drug was administered, patient experienced the following side effects: acarodermatitis, aspiration, condition aggravated, disseminated intravascular coagulation, gastric ulcer, guttate psoriasis, hepatic function abnormal, neutrophil count increased, pneumonia . Temodal dosage: 150 MG/M2;QD;PO 200 MG/M2;QD;PO 200 MG/M2;QD;PO. During the same period patient was treated with BASEN, NATEGLINIDE, PREDONINE, PARULEON, MAGNESIUM OXIDE, DEPAS. Patient died on 04/20/2007.

Temodal Side Effects Report #5301272-1
Temodal side effect was reported by a Physician from JAPAN on Mar 30, 2007. Male patient, 75 years of age, weighting 108.0 lb, was diagnosed with glioblastoma multiforme, malignant neoplasm progression and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood glucose increased, cerebral haemorrhage, condition aggravated, infection , intracranial tumour haemorrhage. Temodal dosage: 300 MG; QD; PO. During the same period patient was treated with RINDERON, DEPAKENE, ACINON, NASEA OD. Patient was hospitalized. Patient died on 01/18/2007.

Temodal Side Effects Report #5445942-3
Temodal side effect was reported by a Physician from JAPAN on Aug 28, 2007. Male patient, 71 years of age, weighting 121.3 lb, was diagnosed with glioblastoma multiforme, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: c-reactive protein increased, condition aggravated, delirium, disease progression, enterocolitis bacterial, escherichia infection, glioblastoma multiforme, hydrocephalus , infection in an immunocompromised host. Temodal dosage: unknown. During the same period patient was treated with RINDERON, PHENOBARBITAL. Patient was hospitalized. Patient died on 12/02/2006.


Temodal Side Effects Report #5878587-1
Temodal side effect was reported by a Physician from JAPAN on Sept 03, 2008. Male patient, 70 years of age, weighting 127.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, depressed level of consciousness, hypophagia, neoplasm progression, oedema. Temodal dosage: 72 MG/M2; QD; PO, 150 MG/M2; QD; PO. During the same period patient was treated with COTRIM, PHENOBARBITAL, FAMOTIDINE, CHLORIDE, MAGNESIUM OXIDE. Patient recovered.

Temodal Side Effects Report #5776194-2
Temodal side effect was reported by a Physician from JAPAN on June 09, 2008. Female patient, 69 years of age, weighting 130.1 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: bone marrow failure, c-reactive protein increased, condition aggravated, depressed level of consciousness, gastric ulcer, hepatic function abnormal, melaena, neoplasm progression, pneumonia . Temodal dosage: 150 MG/M2;QD; PO. During the same period patient was treated with BAKTAR, DEPAKENE, BETAMETHASONE, TAGAMET, ZYPREXA. Patient died on 01/19/2007.

Temodal Side Effects Report #5292610-7
Temodal side effect was reported by a Physician from JAPAN on Jan 24, 2007. Male patient, 68 years of age, weighting 105.8 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: bronchopulmonary aspergillosis, condition aggravated, immunodeficiency, no therapeutic response. Temodal dosage: 75 MG/M2; QD; PO. During the same period patient was treated with DECADRON, DEPAKENE, PERDIPINE, NEW LECICARBON. Patient died on 11/12/2006.

Temodal Side Effects Report #5582800-8
Temodal side effect was reported by a Physician from JAPAN on Dec 21, 2007. Female patient, 65 years of age, weighting 119.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: anaemia, blood albumin decreased, blood alkaline phosphatase increased, blood beta-d-glucan increased, cardiac failure, condition aggravated, disease progression, gastrointestinal haemorrhage, hyperkalaemia. Temodal dosage: 75 MG/M2;QD;PO. During the same period patient was treated with BETAMETHASONE, DEPAKENE R, TAGAMET, NASEA, DOGMATYL, MAALOX, MAGLAX, GLYSENNID. Patient died on 05/09/2007.

Temodal Side Effects Report #5859194-3
Temodal side effect was reported by a Physician from JAPAN on Aug 21, 2008. Female patient, 60 years of age, weighting 167.6 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, disease progression, hydrocephalus . Temodal dosage: 75 MG/M2 QD PO ; 150 MG/M2 QD PO. During the same period patient was treated with COTRIM, KYTRIL, TEGRETOL, GASTER D. Patient died on 09/05/2007.


Temodal Side Effects Report #5698783-6
Temodal side effect was reported by a Physician from CANADA on Mar 28, 2008. Male patient, 58 years of age, weighting 174.2 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, hydrocephalus , neurological symptom. Temodal dosage: 200 MG/M2; QD; PO. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5445957-5
Temodal side effect was reported by a Physician from JAPAN on Aug 28, 2007. Male patient, 56 years of age, weighting 147.7 lb, was diagnosed with glioblastoma multiforme, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, condition aggravated, leukaemia, metastases to bone, metastases to bone marrow, metastases to liver, metastases to pleura, metastases to spine, metastases to spleen. Temodal dosage: 150 MG/M2; QD; PO, 200 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with LIPITOR, FAMOTIDINE, DEPAKENE. Patient was hospitalized. Patient died on 05/26/2007.

Temodal Side Effects Report #5286990-6
Temodal side effect was reported by a Physician from NETHERLANDS on Mar 21, 2007. Female patient, 55 years of age, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: abdominal pain , blood pressure decreased, bone marrow failure, condition aggravated, cushingoid, diverticulum, dyspnoea, febrile neutropenia, haematoma. Temodal dosage: 200 MG/M2; QM. During the same period patient was treated with DEXAMETHASONE. Patient was hospitalized. Patient died.

Temodal Side Effects Report #5428855-2
Temodal side effect was reported by a Physician from AUSTRALIA on Aug 21, 2007. Male patient, 43 years of age, weighting 186.3 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: asthenia, condition aggravated, dehydration, fatigue, mucosal inflammation, oesophageal candidiasis, oral fungal infection. Temodal dosage: 300 MG;QD;PO. During the same period patient was treated with CAELYX, AMLODIPINE, INDAPAMIDE, ASPIRIN, PERINDOPRIL ERBUMINE, DEXAMETHASONE. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5884629-X
Temodal side effect was reported by a Physician from JAPAN on Sept 09, 2008. Female patient, 32 years of age, weighting 127.9 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: candidiasis, condition aggravated, culture stool positive, dehydration, diarrhoea, disease progression, enteritis infectious, enterobacter infection, enterococcal infection. Temodal dosage: 75 MG/M2; QD; PO, 150 MG/M2; QD; PO, 200 MG/M2; QD; PO. During the same period patient was treated with DEPAKENE. Patient died on 09/17/2007.


Temodal Side Effects Report #4757206-1
Temodal side effect was reported by a Consumer or non-health professional from UNITED STATES on Aug 29, 2005. Female patient, weighting 140.0 lb, was diagnosed with glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: asthma , condition aggravated, haemoglobin decreased, nausea , pneumonia aspiration. Temodal dosage: unknown. During the same period patient was treated with RADIATION. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5874887-X
Temodal side effect was reported by a Physician from GERMANY on Aug 29, 2008. Male patient, 71 years of age, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: bone marrow failure, clostridial infection, condition aggravated, disease progression, epstein-barr virus infection, glioblastoma. Temodal dosage: MG; QD; PO. During the same period patient was treated with ZOFRAN, NOVALGIN, COTRIM, NEXIUM, DEXAMETHASONE. Patient was hospitalized. Patient died on 08/17/2008.

Temodal Side Effects Report #5729620-9
Temodal side effect was reported by a Physician from GERMANY on Apr 22, 2008. Male patient, 61 years of age, weighting 196.2 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: abscess , condition aggravated, diabetes mellitus, haematoma, haemoglobin decreased, postoperative wound complication. Temodal dosage: unknown. During the same period patient was treated with DOXORUBICIN. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5926316-5
Temodal side effect was reported by a Physician from GERMANY on Oct 08, 2008. Male patient, 57 years of age, weighting 131.0 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood product transfusion dependent, bone marrow failure, condition aggravated, febrile neutropenia, staphylococcal sepsis. Temodal dosage: 75 MG/M2;QD;PO. During the same period patient was treated with DEXAMETHASONE, METOCLOPRAMID. Patient was hospitalized. Patient died on 06/22/2008.

Temodal Side Effects Report #5500162-9
Temodal side effect was reported by a Physician from GERMANY on Oct 15, 2007. Male patient, 45 years of age, weighting 176.4 lb, was diagnosed with glioblastoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: anorexia, brain oedema, catheter related complication, complex partial seizures, computerised tomogram abnormal, condition aggravated, dizziness , hemiparesis. Temodal dosage: 200 MG/M2; QD; PO. During the same period patient was treated with DOXORUBICIN. Patient was hospitalized. Patient recovered.


Temodal Side Effects Report #5614235-3
Temodal side effect was reported by a Physician from JAPAN on Jan 25, 2008. Female patient, 71 years of age, weighting 114.6 lb, was diagnosed with ependymoma malignant and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, hepatic function abnormal, hydronephrosis, neurogenic bladder, platelet count decreased, pyelonephritis, urinary retention, urinary tract infection , white blood cell count decreased. Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with PREDONINE, ONEALFA, GLAKAY, ALENDRONATE, TAKEPRON OD, FASTIC. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #6094984-6
Temodal side effect was reported by a Physician from JAPAN on Feb 23, 2009. Male patient, 43 years of age, weighting 180.8 lb, was diagnosed with disease recurrence, glioblastoma multiforme and was treated with Temodal. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, cerebral infarction, condition aggravated, disease progression, neoplasm progression, paralysis . Temodal dosage: 150 MG/M2;QD;PO; 150 MG/M2;QD;PO; 150 MG/M2;QD;PO; 150 MG/M2;QD;PO. During the same period patient was treated with KYTRIL. Patient died.

Temodal Side Effects Report #5225703-0
Temodal side effect was reported by a Physician from JAPAN on Jan 22, 2007. Male patient, 63 years of age, weighting 127.9 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: alanine aminotransferase increased, aspartate aminotransferase increased, condition aggravated, hepatitis b , rash . Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with EXCEGRAN, DECADRON, SELBEX, NAUZELIN, NEO MINOPHAGEN C. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5402794-5
Temodal side effect was reported by a Physician from JAPAN on July 23, 2007. Male patient, 63 years of age, weighting 58.00 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, hepatitis , hepatitis b , rash , steroid withdrawal syndrome. Temodal dosage: 120 MG; QD; PO. During the same period patient was treated with ZONISAMIDE, DECADRON, SELBEX, NAUZELIN, NEO MINOPHAGEN C. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5844662-0
Temodal side effect was reported by a Physician from JAPAN on Aug 05, 2008. Male patient, 63 years of age, weighting 127.9 lb, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, hepatitis , hepatitis b , rash . Temodal dosage: 120 MG/M2; QD; PO. During the same period patient was treated with ZONISAMIDE, DECADRON, SELBEX, NAUZELIN, NEO MINOPHAGEN C. Patient was hospitalized. Patient recovered.


Temodal Side Effects Report #5797257-1
Temodal side effect was reported by a Physician from JAPAN on June 20, 2008. Female patient, 57 years of age, weighting 121.3 lb, was diagnosed with anaplastic astrocytoma, recurrent cancer and was treated with Temodal. After drug was administered, patient experienced the following side effects: brain oedema, condition aggravated, hyponatraemia. Temodal dosage: 150 MG/M2; QD; PO; 200 MG/M2; QD; PO; 200 MG/M2; QD; PO; 200 MG/M2; QD; PO; 200 MG/M2; QD; PO; 200 M. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #4729964-3
Temodal side effect was reported by a Physician from HONG KONG on July 19, 2005. Female patient, 49 years of age, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, renal impairment. Temodal dosage: 300MG X5DAYS* ORAL. Patient recovered.

Temodal Side Effects Report #4766958-6
Temodal side effect was reported by a Physician from HONG KONG on Aug 31, 2005. Female patient, 49 years of age, was diagnosed with anaplastic astrocytoma and was treated with Temodal. After drug was administered, patient experienced the following side effects: blood creatinine increased, condition aggravated, renal disorder, renal impairment. Temodal dosage: 300MG X5DAYS ORAL. Patient recovered.

Temodal Side Effects Report #5863869-X
Temodal side effect was reported by a Physician from FRANCE on Aug 22, 2008. Female patient, 69 years of age, was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, febrile neutropenia, neoplasm malignant. Temodal dosage: unknown. Patient was hospitalized. Patient recovered.

Temodal Side Effects Report #5888698-2
Temodal side effect was reported by a Physician from FRANCE on Sept 12, 2008. Female patient, 69 years of age, was treated with Temodal. After drug was administered, patient experienced the following side effects: condition aggravated, febrile neutropenia, neoplasm malignant. Temodal dosage: unknown. Patient was hospitalized. Patient died.