Tacrolimus and renal impairment Patient Reports February 12, 2012

Tacrolimus Side Effects Report #4950834-X
Tacrolimus side effect was reported by a Pharmacist from JAPAN on Nov 24, 2005. Male patient, 27 years of age, was diagnosed with stem cell transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: convulsion, encephalitis viral, encephalopathy, graft versus host disease, herpes simplex , renal impairment. Tacrolimus dosage: unknown. During the same period patient was treated with SANDIMMUNE. Patient died on 01/31/2006.

Tacrolimus Side Effects Report #4955361-1
Tacrolimus side effect was reported by a Pharmacist from JAPAN on Nov 24, 2005. Male patient, 27 years of age, was diagnosed with stem cell transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: convulsion, encephalitis viral, graft versus host disease, herpes simplex , renal impairment. Tacrolimus dosage: unknown. During the same period patient was treated with SANDIMMUNE. Patient died on 01/31/2006.

Tacrolimus Side Effects Report #5483021-X
Tacrolimus side effect was reported by a Physician from JAPAN on Sept 18, 2007. Male patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: refusal of treatment by patient, renal impairment, shock. Tacrolimus dosage: 1.5 MG, ORAL. During the same period patient was treated with BASEN, KINEDAK, AMARYL, FUROSEMIDE, SALOBELLET, PREDNISOLONE, LOXONIN. Patient died on 02/10/2007.

Tacrolimus Side Effects Report #5487493-6
Tacrolimus side effect was reported by a Physician from JAPAN on Sept 28, 2007. Male patient, 74 years of age, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: refusal of treatment by relative, renal impairment, shock. Tacrolimus dosage: 1.5 MG, /D, ORAL. During the same period patient was treated with BASEN, KINEDAK, AMARYL, FUROSEMIDE, SALOBEL, PREDNISONE, LOXONIN. Patient died on 02/10/2007.


Tacrolimus Side Effects Report #5201712-2
Tacrolimus side effect was reported by a Physician from JAPAN on Dec 20, 2006. Female patient, 71 years of age, weighting 88.18 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: bronchiectasis, herpes simplex , hyperglycaemia, renal impairment. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, PREDNISOLONE, METHOTREXATE, MOBIC, VOLTAREN. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5239142-X
Tacrolimus side effect was reported by a Physician from JAPAN on Jan 25, 2007. Female patient, 71 years of age, weighting 88.18 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: bronchitis , herpes simplex , hyperglycaemia, renal impairment. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, PREDNISOLONE, METHOTREXATE, MOBIC, VOLTAREN. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5015754-3
Tacrolimus side effect was reported by a Physician from JAPAN on May 11, 2006. Male patient, 57 years of age, weighting 123.5 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: diabetes mellitus inadequate control, glucose urine present, hepatic function abnormal, interstitial lung disease, renal impairment. Tacrolimus dosage: 3MG, UID/QD; ORAL. During the same period patient was treated with PREDNISOLONE, LOXONIN, RHEUMATREX. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5207326-2
Tacrolimus side effect was reported by a Physician from JAPAN on Dec 27, 2006. Female patient, 48 years of age, weighting 90.39 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: hyperkalaemia, renal impairment, viral pericarditis. Tacrolimus dosage: 3 MG, ORAL; SEE IMAGE. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, PREDNISOLONE, SULFAMETHOXAZOLE, DIFLUCAN, LANSOPRAZOLE, ISODINE, FUNGIZONE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5230401-3
Tacrolimus side effect was reported by a Physician from JAPAN on Jan 19, 2007. Female patient, 48 years of age, weighting 90.39 lb, was diagnosed with rheumatoid arthritis  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: arthralgia, electrocardiogram st segment elevation, hyperkalaemia, pharyngolaryngeal pain, pleural effusion, renal impairment, upper respiratory tract inflammation, viral pericarditis. Tacrolimus dosage: unknown. During the same period patient was treated with TACROLIMUS CAPSULES, TACROLIMUS CAPSULES, PREDNISOLONE, BAKTAR, DIFLUCAN, LANSOPRAZOLE, ISODINE, FUNGIZONE. Patient was hospitalized. Patient recovered.


Tacrolimus Side Effects Report #4767124-0
Tacrolimus side effect was reported by a Physician from UNITED STATES on Aug 25, 2005. Female patient, 65 years of age, weighting 94.14 lb, was diagnosed with renal transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: abdominal pain lower, bk virus infection, kidney transplant rejection, polyomavirus interstitial nephritis, renal impairment. Tacrolimus dosage: 3.00 MG, ORAL. During the same period patient was treated with CELLCEPT, PREDNISONE, RAPAMUNE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #4767125-2
Tacrolimus side effect was reported by a Physician from UNITED STATES on Aug 25, 2005. Female patient, 65 years of age, weighting 94.14 lb, was diagnosed with renal transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: bk virus infection, kidney transplant rejection, polyomavirus interstitial nephritis, renal impairment. Tacrolimus dosage: 3.00 MG, ORAL. During the same period patient was treated with CELLCEPT, PREDNISONE, RAPAMUNE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #4567237-2
Tacrolimus side effect was reported by a Consumer or non-health professional from on Jan 26, 2005. Male patient, 56 years of age, was diagnosed with renal transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: cytomegalovirus viraemia, incision site haemorrhage, pleural effusion, renal impairment, wound infection staphylococcal. Tacrolimus dosage: unknown. During the same period patient was treated with CYCLOSPORINE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5982137-9
Tacrolimus side effect was reported by a Health Professional from UNITED KINGDOM on Nov 12, 2008. Female patient, 40 years of age, was diagnosed with renal transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: bladder transitional cell carcinoma, kidney transplant rejection, polyomavirus-associated nephropathy, renal impairment. Tacrolimus dosage: unknown. During the same period patient was treated with AZATHIOPRINE, CYCLOSPORINE, MYCOPHENOLATE MOFETIL, PREDNISOLONE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5616235-6
Tacrolimus side effect was reported by a Physician from SWITZERLAND on Nov 12, 2007. Female patient, 26 years of age, was diagnosed with renal transplant, migraine  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, kidney fibrosis, migraine , nephrolithiasis, renal arteriosclerosis, renal impairment, renal ischaemia. Tacrolimus dosage: 1.5 MG, BID,; 1.5 MG, UID/QD,. During the same period patient was treated with ZOLMITRIPTAN, MYCOPHENOLATE MOFETIL, PREDNISOLONE ACETATE, CONTRACEPTIVES NOS, MAGNESIUM. Patient recovered.


Tacrolimus Side Effects Report #5444333-9
Tacrolimus side effect was reported by a Physician from TUNISIA on Aug 16, 2007. Male patient, 14 years of age, was diagnosed with renal transplant and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: blood lactate dehydrogenase increased, haematocrit decreased, haemoglobin decreased, renal impairment, thrombotic microangiopathy, white blood cell count decreased. Tacrolimus dosage: unknown. During the same period patient was treated with PREDNISONE, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #4973102-9
Tacrolimus side effect was reported by a Physician from CZECH REPUBLIC on Mar 28, 2006. Female patient, 52 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: arteriosclerosis, cholelithiasis, metastases to liver, mitral valve calcification, renal impairment. Tacrolimus dosage: unknown. During the same period patient was treated with ISOSORBIDE DINITRATE, MOLSIDOMINE, WARFARIN, FAMOTIDINE, ALFACALCIDOL, CALCIUM CARBONATE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5158643-6
Tacrolimus side effect was reported by a Consumer or non-health professional from FRANCE on Nov 08, 2006. Male patient, 38 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: kidney transplant rejection, pyrexia, renal impairment, thrombotic microangiopathy. Tacrolimus dosage: 11 MG 1X PER 1 DAY; ORAL, 10 MG 1X PER 1 DAY; ORAL, 11 MG 1X PER 1 DAY; ORAL. During the same period patient was treated with CELLCEPT, MEDROL. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5041620-3
Tacrolimus side effect was reported by a Health Professional from GERMANY on June 20, 2006. Male patient, 32 years of age, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: complications of transplanted kidney, procedural complication, renal impairment, ultrasound kidney abnormal, urine output decreased. Tacrolimus dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, GLUCOCORTICOOIDS. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5594506-X
Tacrolimus side effect was reported by a Physician from GERMANY on Jan 16, 2008. Male patient, weighting 158.7 lb, was diagnosed with prophylaxis against transplant rejection and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: renal impairment. Tacrolimus dosage: unknown. During the same period patient was treated with GLUCOCORTICOIDS, MYCOPHENOLATE MOFETIL. Patient was hospitalized. Patient recovered.


Tacrolimus Side Effects Report #5698791-5
Tacrolimus side effect was reported by a Physician from JAPAN on Jan 11, 2008. Female patient, 55 years of age, weighting 109.8 lb, was diagnosed with lupus nephritis and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: diabetes mellitus, glycosylated haemoglobin increased, lung infection, nephritis interstitial, pleural effusion, pyrexia, renal impairment, underdose. Tacrolimus dosage: unknown. During the same period patient was treated with PREDNISOLONE, LIPITOR, LANSOPRAZOLE, ASPIRIN, ALFAROL. Patient was hospitalized and became disabled. Patient recovered.

Tacrolimus Side Effects Report #5578688-1
Tacrolimus side effect was reported by a Physician from GERMANY on Dec 11, 2007. Female patient, 26 years of age, was diagnosed with lung transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: hypokalaemia, myocardial ischaemia, nephropathy toxic, pulmonary function test decreased, renal impairment. Tacrolimus dosage: unknown. During the same period patient was treated with MYCOPHENOLATE MOFETIL, CORTICOSTEROIDS. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #4570310-6
Tacrolimus side effect was reported by a Pharmacist from on Jan 27, 2005. Male patient, 20 years of age, weighting 108.2 lb, was diagnosed with lung transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, lung transplant rejection, renal impairment, thrombocytopenia. Tacrolimus dosage: 3MG TWO TIMES/DAY ORAL. During the same period patient was treated with PHYTONADIONE, FAMOTIDINE, DILTIAZEM, GANCICLOVIR, DOCUSATE, SULFAMETHOXAZOLE, CLONIDINE, FERROUS SULPHATE. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5314704-X
Tacrolimus side effect was reported by a Health Professional from BELGIUM on Apr 13, 2007. Female patient, 49 years of age, was diagnosed with liver transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: congenital cystic kidney disease, dialysis , renal impairment. Tacrolimus dosage: 2 MG, BID, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, DACLIZUMAB, METHYLPREDNISOLONE, AMPICILLIN, CEFOTAXIME, TOBRAMYCIN. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5325849-2
Tacrolimus side effect was reported by a Health Professional from BELGIUM on Apr 26, 2007. Female patient, 49 years of age, was diagnosed with liver transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: condition aggravated, congenital cystic kidney disease, dialysis , renal impairment. Tacrolimus dosage: 2 MG, BID, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, DACLIZUMAB, METHYLPREDNISOLONE, AMPICILLIN, CEFOTAXIME, TOBRAMYCIN. Patient was hospitalized. Patient recovered.


Tacrolimus Side Effects Report #5330590-6
Tacrolimus side effect was reported by a Health Professional from BELGIUM on Apr 30, 2007. Female patient, 49 years of age, was diagnosed with liver transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: congenital cystic kidney disease, dialysis , renal impairment. Tacrolimus dosage: 2 MG, BID, ORAL. During the same period patient was treated with MYCOPHENOLATE MOFETIL, MYCOPHENOLATE MOFETIL, DACLIZUMAB, METHYLPREDNISOLONE, AMPICILLIN, CEFOTAXIME, TOBRAMYCIN. Patient was hospitalized. Patient recovered.

Tacrolimus Side Effects Report #5407349-4
Tacrolimus side effect was reported by a Health Professional from FRANCE on July 20, 2007. Female patient, child 3 years of age, weighting 39.68 lb, was diagnosed with liver transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: lung disorder, renal impairment, sepsis , thrombocytopenia. Tacrolimus dosage: 0.8 MG, BID; 1 MG, BID. During the same period patient was treated with SIMULECT. Patient died.

Tacrolimus Side Effects Report #5664394-1
Tacrolimus side effect was reported by a Pharmacist from UNITED STATES on Mar 11, 2008. Male patient, 28 years of age, weighting 145.5 lb, was diagnosed with heart transplant  and was treated with Tacrolimus. After drug was administered, patient experienced the following side effects: convulsion, renal impairment. Tacrolimus dosage: 2 MG BID PO. During the same period patient was treated with VALGANCYCLOVIR. Patient was hospitalized. Patient recovered.